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Items: 18


Regulatory Mechanism of the Atypical AP-1-Like Transcription Factor Yap1 in Cryptococcus neoformans.

So YS, Maeng S, Yang DH, Kim H, Lee KT, Yu SR, Tenor JL, Giri VK, Toffaletti DL, Arras S, Fraser JA, Perfect JR, Bahn YS.

mSphere. 2019 Nov 20;4(6). pii: e00785-19. doi: 10.1128/mSphere.00785-19.


Genotypic diversity and clinical outcome of cryptococcosis in renal transplant recipients in Brazil.

Ponzio V, Chen Y, Rodrigues AM, Tenor JL, Toffaletti DL, Medina-Pestana JO, Colombo AL, Perfect JR.

Emerg Microbes Infect. 2019;8(1):119-129. doi: 10.1080/22221751.2018.1562849.


In Vitro and In Vivo Evaluation of APX001A/APX001 and Other Gwt1 Inhibitors against Cryptococcus.

Shaw KJ, Schell WA, Covel J, Duboc G, Giamberardino C, Kapoor M, Moloney M, Soltow QA, Tenor JL, Toffaletti DL, Trzoss M, Webb P, Perfect JR.

Antimicrob Agents Chemother. 2018 Jul 27;62(8). pii: e00523-18. doi: 10.1128/AAC.00523-18. Print 2018 Aug.


Structural and In Vivo Studies on Trehalose-6-Phosphate Synthase from Pathogenic Fungi Provide Insights into Its Catalytic Mechanism, Biological Necessity, and Potential for Novel Antifungal Drug Design.

Miao Y, Tenor JL, Toffaletti DL, Maskarinec SA, Liu J, Lee RE, Perfect JR, Brennan RG.

MBio. 2017 Jul 25;8(4). pii: e00643-17. doi: 10.1128/mBio.00643-17.


Population genomics and the evolution of virulence in the fungal pathogen Cryptococcus neoformans.

Desjardins CA, Giamberardino C, Sykes SM, Yu CH, Tenor JL, Chen Y, Yang T, Jones AM, Sun S, Haverkamp MR, Heitman J, Litvintseva AP, Perfect JR, Cuomo CA.

Genome Res. 2017 Jul;27(7):1207-1219. doi: 10.1101/gr.218727.116.


Microevolution of Serial Clinical Isolates of Cryptococcus neoformans var. grubii and C. gattii.

Chen Y, Farrer RA, Giamberardino C, Sakthikumar S, Jones A, Yang T, Tenor JL, Wagih O, Van Wyk M, Govender NP, Mitchell TG, Litvintseva AP, Cuomo CA, Perfect JR.

MBio. 2017 Mar 7;8(2). pii: e00166-17. doi: 10.1128/mBio.00166-17.


Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis.

Miao Y, Tenor JL, Toffaletti DL, Washington EJ, Liu J, Shadrick WR, Schumacher MA, Lee RE, Perfect JR, Brennan RG.

Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):7148-53. doi: 10.1073/pnas.1601774113. Epub 2016 Jun 15.


Trehalose pathway as an antifungal target.

Perfect JR, Tenor JL, Miao Y, Brennan RG.

Virulence. 2017 Feb 17;8(2):143-149. doi: 10.1080/21505594.2016.1195529. Epub 2016 Jun 1. Review.


Live Imaging of Host-Parasite Interactions in a Zebrafish Infection Model Reveals Cryptococcal Determinants of Virulence and Central Nervous System Invasion.

Tenor JL, Oehlers SH, Yang JL, Tobin DM, Perfect JR.

MBio. 2015 Sep 29;6(5):e01425-15. doi: 10.1128/mBio.01425-15.


The Cryptococcus neoformans transcriptome at the site of human meningitis.

Chen Y, Toffaletti DL, Tenor JL, Litvintseva AP, Fang C, Mitchell TG, McDonald TR, Nielsen K, Boulware DR, Bicanic T, Perfect JR.

MBio. 2014 Feb 4;5(1):e01087-13. doi: 10.1128/mBio.01087-13.


Nitrogen source-dependent capsule induction in human-pathogenic cryptococcus species.

Frazzitta AE, Vora H, Price MS, Tenor JL, Betancourt-Quiroz M, Toffaletti DL, Cheng N, Perfect JR.

Eukaryot Cell. 2013 Nov;12(11):1439-50. doi: 10.1128/EC.00169-13. Epub 2013 Aug 23.


Pleiotropic effects of deubiquitinating enzyme Ubp5 on growth and pathogenesis of Cryptococcus neoformans.

Fang W, Price MS, Toffaletti DL, Tenor J, Betancourt-Quiroz M, Price JL, Pan WH, Liao WQ, Perfect JR.

PLoS One. 2012;7(6):e38326. doi: 10.1371/journal.pone.0038326. Epub 2012 Jun 14.


Survival defects of Cryptococcus neoformans mutants exposed to human cerebrospinal fluid result in attenuated virulence in an experimental model of meningitis.

Lee A, Toffaletti DL, Tenor J, Soderblom EJ, Thompson JW, Moseley MA, Price M, Perfect JR.

Infect Immun. 2010 Oct;78(10):4213-25. doi: 10.1128/IAI.00551-10. Epub 2010 Aug 9.


A conserved PMK-1/p38 MAPK is required in caenorhabditis elegans tissue-specific immune response to Yersinia pestis infection.

Bolz DD, Tenor JL, Aballay A.

J Biol Chem. 2010 Apr 2;285(14):10832-40. doi: 10.1074/jbc.M109.091629. Epub 2010 Feb 4.


A conserved Toll-like receptor is required for Caenorhabditis elegans innate immunity.

Tenor JL, Aballay A.

EMBO Rep. 2008 Jan;9(1):103-9. Epub 2007 Nov 2.


Colonial differentiation in Streptomyces coelicolor depends on translation of a specific codon within the adpA gene.

Nguyen KT, Tenor J, Stettler H, Nguyen LT, Nguyen LD, Thompson CJ.

J Bacteriol. 2003 Dec;185(24):7291-6.


A connection between stress and development in the multicellular prokaryote Streptomyces coelicolor A3(2).

Kelemen GH, Viollier PH, Tenor J, Marri L, Buttner MJ, Thompson CJ.

Mol Microbiol. 2001 May;40(4):804-14.

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