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Items: 11


Insulin Signaling Regulates Oocyte Quality Maintenance with Age via Cathepsin B Activity.

Templeman NM, Luo S, Kaletsky R, Shi C, Ashraf J, Keyes W, Murphy CT.

Curr Biol. 2018 Mar 5;28(5):753-760.e4. doi: 10.1016/j.cub.2018.01.052. Epub 2018 Feb 22.


Regulation of reproduction and longevity by nutrient-sensing pathways.

Templeman NM, Murphy CT.

J Cell Biol. 2018 Jan 2;217(1):93-106. doi: 10.1083/jcb.201707168. Epub 2017 Oct 26. Review.


Reduced Circulating Insulin Enhances Insulin Sensitivity in Old Mice and Extends Lifespan.

Templeman NM, Flibotte S, Chik JHL, Sinha S, Lim GE, Foster LJ, Nislow C, Johnson JD.

Cell Rep. 2017 Jul 11;20(2):451-463. doi: 10.1016/j.celrep.2017.06.048.


A causal role for hyperinsulinemia in obesity.

Templeman NM, Skovsø S, Page MM, Lim GE, Johnson JD.

J Endocrinol. 2017 Mar;232(3):R173-R183. doi: 10.1530/JOE-16-0449. Epub 2017 Jan 4. Review.


Caloric Restriction Paradoxically Increases Adiposity in Mice With Genetically Reduced Insulin.

Dionne DA, Skovsø S, Templeman NM, Clee SM, Johnson JD.

Endocrinology. 2016 Jul;157(7):2724-34. doi: 10.1210/en.2016-1102. Epub 2016 May 4.


Hyper-Variability in Circulating Insulin, High Fat Feeding Outcomes, and Effects of Reducing Ins2 Dosage in Male Ins1-Null Mice in a Specific Pathogen-Free Facility.

Templeman NM, Mehran AE, Johnson JD.

PLoS One. 2016 Apr 7;11(4):e0153280. doi: 10.1371/journal.pone.0153280. eCollection 2016.


Suppression of hyperinsulinaemia in growing female mice provides long-term protection against obesity.

Templeman NM, Clee SM, Johnson JD.

Diabetologia. 2015 Oct;58(10):2392-402. doi: 10.1007/s00125-015-3676-7. Epub 2015 Jul 9.


Linking physiological and cellular responses to thermal stress: β-adrenergic blockade reduces the heat shock response in fish.

Templeman NM, LeBlanc S, Perry SF, Currie S.

J Comp Physiol B. 2014 Aug;184(6):719-28. doi: 10.1007/s00360-014-0831-2. Epub 2014 Apr 24.


Hyperinsulinemia drives diet-induced obesity independently of brain insulin production.

Mehran AE, Templeman NM, Brigidi GS, Lim GE, Chu KY, Hu X, Botezelli JD, Asadi A, Hoffman BG, Kieffer TJ, Bamji SX, Clee SM, Johnson JD.

Cell Metab. 2012 Dec 5;16(6):723-37. doi: 10.1016/j.cmet.2012.10.019.


Do mice bred selectively for high locomotor activity have a greater reliance on lipids to power submaximal aerobic exercise?

Templeman NM, Schutz H, Garland T Jr, McClelland GB.

Am J Physiol Regul Integr Comp Physiol. 2012 Jul 1;303(1):R101-11. doi: 10.1152/ajpregu.00511.2011. Epub 2012 May 9.


Chronic hypoxia- and cold-induced changes in cardiac enzyme and gene expression in CD-1 mice.

Templeman NM, Beaudry JL, Le Moine CM, McClelland GB.

Biochim Biophys Acta. 2010 Dec;1800(12):1248-55. doi: 10.1016/j.bbagen.2010.08.004. Epub 2010 Aug 27.


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