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Items: 1 to 50 of 64

1.

Long-term efficacy of docosahexaenoic acid (DHA) for Spinocerebellar Ataxia 38 (SCA38) treatment: An open label extension study.

Manes M, Alberici A, Di Gregorio E, Boccone L, Premi E, Mitro N, Pasolini MP, Pani C, Paghera B, Orsi L, Costanzi C, Ferrero M, Tempia F, Caruso D, Padovani A, Brusco A, Borroni B.

Parkinsonism Relat Disord. 2019 Jun;63:191-194. doi: 10.1016/j.parkreldis.2019.02.040. Epub 2019 Mar 7.

PMID:
30862453
2.

The Emerging Role of Altered Cerebellar Synaptic Processing in Alzheimer's Disease.

Hoxha E, Lippiello P, Zurlo F, Balbo I, Santamaria R, Tempia F, Miniaci MC.

Front Aging Neurosci. 2018 Nov 27;10:396. doi: 10.3389/fnagi.2018.00396. eCollection 2018. Review.

3.

Mice harbouring a SCA28 patient mutation in AFG3L2 develop late-onset ataxia associated with enhanced mitochondrial proteotoxicity.

Mancini C, Hoxha E, Iommarini L, Brussino A, Richter U, Montarolo F, Cagnoli C, Parolisi R, Gondor Morosini DI, Nicolò V, Maltecca F, Muratori L, Ronchi G, Geuna S, Arnaboldi F, Donetti E, Giorgio E, Cavalieri S, Di Gregorio E, Pozzi E, Ferrero M, Riberi E, Casari G, Altruda F, Turco E, Gasparre G, Battersby BJ, Porcelli AM, Ferrero E, Brusco A, Tempia F.

Neurobiol Dis. 2019 Apr;124:14-28. doi: 10.1016/j.nbd.2018.10.018. Epub 2018 Oct 30.

PMID:
30389403
4.

Emerging roles of Fgf14 in behavioral control.

Hoxha E, Marcinnò A, Montarolo F, Masante L, Balbo I, Ravera F, Laezza F, Tempia F.

Behav Brain Res. 2019 Jan 1;356:257-265. doi: 10.1016/j.bbr.2018.08.034. Epub 2018 Sep 3.

PMID:
30189289
5.

Purkinje Cell Signaling Deficits in Animal Models of Ataxia.

Hoxha E, Balbo I, Miniaci MC, Tempia F.

Front Synaptic Neurosci. 2018 Apr 26;10:6. doi: 10.3389/fnsyn.2018.00006. eCollection 2018. Review.

6.

Sox2 conditional mutation in mouse causes ataxic symptoms, cerebellar vermis hypoplasia, and postnatal defects of Bergmann glia.

Cerrato V, Mercurio S, Leto K, Fucà E, Hoxha E, Bottes S, Pagin M, Milanese M, Ngan CY, Concina G, Ottolenghi S, Wei CL, Bonanno G, Pavesi G, Tempia F, Buffo A, Nicolis SK.

Glia. 2018 Sep;66(9):1929-1946. doi: 10.1002/glia.23448. Epub 2018 May 6.

7.

Motor Deficits and Cerebellar Atrophy in Elovl5 Knock Out Mice.

Hoxha E, Gabriele RMC, Balbo I, Ravera F, Masante L, Zambelli V, Albergo C, Mitro N, Caruso D, Di Gregorio E, Brusco A, Borroni B, Tempia F.

Front Cell Neurosci. 2017 Oct 30;11:343. doi: 10.3389/fncel.2017.00343. eCollection 2017.

8.

Docosahexaenoic acid is a beneficial replacement treatment for spinocerebellar ataxia 38.

Manes M, Alberici A, Di Gregorio E, Boccone L, Premi E, Mitro N, Pasolini MP, Pani C, Paghera B, Perani D, Orsi L, Costanzi C, Ferrero M, Zoppo A, Tempia F, Caruso D, Grassi M, Padovani A, Brusco A, Borroni B.

Ann Neurol. 2017 Oct;82(4):615-621. doi: 10.1002/ana.25059. Epub 2017 Oct 22.

9.

Maturation, Refinement, and Serotonergic Modulation of Cerebellar Cortical Circuits in Normal Development and in Murine Models of Autism.

Hoxha E, Lippiello P, Scelfo B, Tempia F, Ghirardi M, Miniaci MC.

Neural Plast. 2017;2017:6595740. doi: 10.1155/2017/6595740. Epub 2017 Aug 15. Review.

10.

Modulation, Plasticity and Pathophysiology of the Parallel Fiber-Purkinje Cell Synapse.

Hoxha E, Tempia F, Lippiello P, Miniaci MC.

Front Synaptic Neurosci. 2016 Nov 3;8:35. eCollection 2016. Review.

11.

Genetic deletion of fibroblast growth factor 14 recapitulates phenotypic alterations underlying cognitive impairment associated with schizophrenia.

Alshammari TK, Alshammari MA, Nenov MN, Hoxha E, Cambiaghi M, Marcinno A, James TF, Singh P, Labate D, Li J, Meltzer HY, Sacchetti B, Tempia F, Laezza F.

Transl Psychiatry. 2016 May 10;6:e806. doi: 10.1038/tp.2016.66.

12.

Clinical and neuroradiological features of spinocerebellar ataxia 38 (SCA38).

Borroni B, Di Gregorio E, Orsi L, Vaula G, Costanzi C, Tempia F, Mitro N, Caruso D, Manes M, Pinessi L, Padovani A, Brusco A, Boccone L.

Parkinsonism Relat Disord. 2016 Jul;28:80-6. doi: 10.1016/j.parkreldis.2016.04.030. Epub 2016 Apr 27.

13.

Propagation of Neuronal Damage to Embryonic Grafts Transplanted in the Hippocampus of Murine Models of Alzheimer's Disease.

Sadallah M, Labat-Gest V, Tempia F.

Rejuvenation Res. 2015 Dec;18(6):554-63. doi: 10.1089/rej.2015.1672. Epub 2015 Nov 5.

14.

Autistic-Like Traits and Cerebellar Dysfunction in Purkinje Cell PTEN Knock-Out Mice.

Cupolillo D, Hoxha E, Faralli A, De Luca A, Rossi F, Tempia F, Carulli D.

Neuropsychopharmacology. 2016 May;41(6):1457-66. doi: 10.1038/npp.2015.339. Epub 2015 Nov 5.

15.

The 5-HT7 receptor triggers cerebellar long-term synaptic depression via PKC-MAPK.

Lippiello P, Hoxha E, Speranza L, Volpicelli F, Ferraro A, Leopoldo M, Lacivita E, Perrone-Capano C, Tempia F, Miniaci MC.

Neuropharmacology. 2016 Feb;101:426-38. doi: 10.1016/j.neuropharm.2015.10.019. Epub 2015 Oct 23.

16.

Parallel fiber to Purkinje cell synaptic impairment in a mouse model of spinocerebellar ataxia type 27.

Tempia F, Hoxha E, Negro G, Alshammari MA, Alshammari TK, Panova-Elektronova N, Laezza F.

Front Cell Neurosci. 2015 Jun 4;9:205. doi: 10.3389/fncel.2015.00205. eCollection 2015.

17.

Peripheral adipose tissue insulin resistance alters lipid composition and function of hippocampal synapses.

Sallam HS, Tumurbaatar B, Zhang WR, Tuvdendorj D, Chandalia M, Tempia F, Laezza F, Taglialatela G, Abate N.

J Neurochem. 2015 Apr;133(1):125-33. doi: 10.1111/jnc.13043. Epub 2015 Feb 26.

18.

Impaired firing properties of dentate granule neurons in an Alzheimer's disease animal model are rescued by PPARγ agonism.

Nenov MN, Tempia F, Denner L, Dineley KT, Laezza F.

J Neurophysiol. 2015 Mar 15;113(6):1712-26. doi: 10.1152/jn.00419.2014. Epub 2014 Dec 24.

19.

Noradrenergic modulation of the parallel fiber-Purkinje cell synapse in mouse cerebellum.

Lippiello P, Hoxha E, Volpicelli F, Lo Duca G, Tempia F, Miniaci MC.

Neuropharmacology. 2015 Feb;89:33-42. doi: 10.1016/j.neuropharm.2014.08.016. Epub 2014 Sep 9.

20.

ELOVL5 mutations cause spinocerebellar ataxia 38.

Di Gregorio E, Borroni B, Giorgio E, Lacerenza D, Ferrero M, Lo Buono N, Ragusa N, Mancini C, Gaussen M, Calcia A, Mitro N, Hoxha E, Mura I, Coviello DA, Moon YA, Tesson C, Vaula G, Couarch P, Orsi L, Duregon E, Papotti MG, Deleuze JF, Imbert J, Costanzi C, Padovani A, Giunti P, Maillet-Vioud M, Durr A, Brice A, Tempia F, Funaro A, Boccone L, Caruso D, Stevanin G, Brusco A.

Am J Hum Genet. 2014 Aug 7;95(2):209-17. doi: 10.1016/j.ajhg.2014.07.001. Epub 2014 Jul 24.

21.

Early enriched environment exposure protects spatial memory and accelerates amyloid plaque formation in APP(Swe)/PS1(L166P) mice.

Montarolo F, Parolisi R, Hoxha E, Boda E, Tempia F.

PLoS One. 2013 Jul 24;8(7):e69381. doi: 10.1371/journal.pone.0069381. Print 2013.

22.

A de novo X;8 translocation creates a PTK2-THOC2 gene fusion with THOC2 expression knockdown in a patient with psychomotor retardation and congenital cerebellar hypoplasia.

Di Gregorio E, Bianchi FT, Schiavi A, Chiotto AM, Rolando M, Verdun di Cantogno L, Grosso E, Cavalieri S, Calcia A, Lacerenza D, Zuffardi O, Retta SF, Stevanin G, Marelli C, Durr A, Forlani S, Chelly J, Montarolo F, Tempia F, Beggs HE, Reed R, Squadrone S, Abete MC, Brussino A, Ventura N, Di Cunto F, Brusco A.

J Med Genet. 2013 Aug;50(8):543-51. doi: 10.1136/jmedgenet-2013-101542. Epub 2013 Jun 7.

23.

Motor dysfunction and cerebellar Purkinje cell firing impairment in Ebf2 null mice.

Hoxha E, Tonini R, Montarolo F, Croci L, Consalez GG, Tempia F.

Mol Cell Neurosci. 2013 Jan;52:51-61. doi: 10.1016/j.mcn.2012.09.002. Epub 2012 Sep 18.

24.

Excitability and synaptic alterations in the cerebellum of APP/PS1 mice.

Hoxha E, Boda E, Montarolo F, Parolisi R, Tempia F.

PLoS One. 2012;7(4):e34726. doi: 10.1371/journal.pone.0034726. Epub 2012 Apr 12.

25.

The GPR17 receptor in NG2 expressing cells: focus on in vivo cell maturation and participation in acute trauma and chronic damage.

Boda E, Viganò F, Rosa P, Fumagalli M, Labat-Gest V, Tempia F, Abbracchio MP, Dimou L, Buffo A.

Glia. 2011 Dec;59(12):1958-73. doi: 10.1002/glia.21237. Epub 2011 Sep 28.

26.

Brain expression of Kv3 subunits during development, adulthood and aging and in a murine model of Alzheimer's disease.

Boda E, Hoxha E, Pini A, Montarolo F, Tempia F.

J Mol Neurosci. 2012 Mar;46(3):606-15. doi: 10.1007/s12031-011-9648-6. Epub 2011 Sep 13.

27.

The collagen chaperone HSP47 is a new interactor of APP that affects the levels of extracellular beta-amyloid peptides.

Bianchi FT, Camera P, Ala U, Imperiale D, Migheli A, Boda E, Tempia F, Berto G, Bosio Y, Oddo S, LaFerla FM, Taraglio S, Dotti CG, Di Cunto F.

PLoS One. 2011;6(7):e22370. doi: 10.1371/journal.pone.0022370. Epub 2011 Jul 28.

28.

Mouse brain expression patterns of Spg7, Afg3l1, and Afg3l2 transcripts, encoding for the mitochondrial m-AAA protease.

Sacco T, Boda E, Hoxha E, Pizzo R, Cagnoli C, Brusco A, Tempia F.

BMC Neurosci. 2010 Apr 28;11:55. doi: 10.1186/1471-2202-11-55.

29.

Mutations in the mitochondrial protease gene AFG3L2 cause dominant hereditary ataxia SCA28.

Di Bella D, Lazzaro F, Brusco A, Plumari M, Battaglia G, Pastore A, Finardi A, Cagnoli C, Tempia F, Frontali M, Veneziano L, Sacco T, Boda E, Brussino A, Bonn F, Castellotti B, Baratta S, Mariotti C, Gellera C, Fracasso V, Magri S, Langer T, Plevani P, Di Donato S, Muzi-Falconi M, Taroni F.

Nat Genet. 2010 Apr;42(4):313-21. doi: 10.1038/ng.544. Epub 2010 Mar 7.

PMID:
20208537
30.

Selection of reference genes for quantitative real-time RT-PCR studies in mouse brain.

Boda E, Pini A, Hoxha E, Parolisi R, Tempia F.

J Mol Neurosci. 2009 Mar;37(3):238-53. doi: 10.1007/s12031-008-9128-9. Epub 2008 Jul 8.

PMID:
18607772
31.

Properties and expression of Kv3 channels in cerebellar Purkinje cells.

Sacco T, De Luca A, Tempia F.

Mol Cell Neurosci. 2006 Oct;33(2):170-9. Epub 2006 Sep 1.

32.

Unravelling the Purkinje neuron.

Rossi F, Tempia F.

Cerebellum. 2006;5(2):75-6.

PMID:
16818381
33.

Resurgent current and voltage sensor trapping enhanced activation by a beta-scorpion toxin solely in Nav1.6 channel. Significance in mice Purkinje neurons.

Schiavon E, Sacco T, Cassulini RR, Gurrola G, Tempia F, Possani LD, Wanke E.

J Biol Chem. 2006 Jul 21;281(29):20326-37. Epub 2006 May 15.

34.

Membrane excitability and fear conditioning in cerebellar Purkinje cell.

Zhu L, Scelfo B, Tempia F, Sacchetti B, Strata P.

Neuroscience. 2006 Jul 7;140(3):801-10. Epub 2006 Mar 31.

PMID:
16580140
35.

Expression pattern of the ether-a-go-go-related (ERG) family proteins in the adult mouse central nervous system: evidence for coassembly of different subunits.

Guasti L, Cilia E, Crociani O, Hofmann G, Polvani S, Becchetti A, Wanke E, Tempia F, Arcangeli A.

J Comp Neurol. 2005 Oct 17;491(2):157-74.

PMID:
16127690
36.

Long-term synaptic changes induced in the cerebellar cortex by fear conditioning.

Sacchetti B, Scelfo B, Tempia F, Strata P.

Neuron. 2004 Jun 24;42(6):973-82.

38.

Functional roles of an ERG current isolated in cerebellar Purkinje neurons.

Sacco T, Bruno A, Wanke E, Tempia F.

J Neurophysiol. 2003 Sep;90(3):1817-28. Epub 2003 May 15.

39.
40.
41.
42.

Postsynaptic currents in deep cerebellar nuclei.

Anchisi D, Scelfo B, Tempia F.

J Neurophysiol. 2001 Jan;85(1):323-31.

43.

Elevation of intradendritic sodium concentration mediated by synaptic activation of metabotropic glutamate receptors in cerebellar Purkinje cells.

Knöpfel T, Anchisi D, Alojado ME, Tempia F, Strata P.

Eur J Neurosci. 2000 Jun;12(6):2199-204.

PMID:
10886360
44.

Atm-deficient mice Purkinje cells show age-dependent defects in calcium spike bursts and calcium currents.

Chiesa N, Barlow C, Wynshaw-Boris A, Strata P, Tempia F.

Neuroscience. 2000;96(3):575-83.

PMID:
10717437
45.

Postsynaptic current mediated by metabotropic glutamate receptors in cerebellar Purkinje cells.

Tempia F, Miniaci MC, Anchisi D, Strata P.

J Neurophysiol. 1998 Aug;80(2):520-8.

46.

A pacemaker current in dye-coupled hilar interneurons contributes to the generation of giant GABAergic potentials in developing hippocampus.

Strata F, Atzori M, Molnar M, Ugolini G, Tempia F, Cherubini E.

J Neurosci. 1997 Feb 15;17(4):1435-46.

47.

Reciprocal trophic interactions between climbing fibres and Purkinje cells in the rat cerebellum.

Strata P, Tempia F, Zagrebelsky M, Rossi F.

Prog Brain Res. 1997;114:263-82. Review.

PMID:
9193149
48.
49.

Fractional Ca2+ currents through somatic and dendritic glutamate receptor channels of rat hippocampal CA1 pyramidal neurones.

Garaschuk O, Schneggenburger R, Schirra C, Tempia F, Konnerth A.

J Physiol. 1996 Mar 15;491 ( Pt 3):757-72.

50.

Fractional calcium current through neuronal AMPA-receptor channels with a low calcium permeability.

Tempia F, Kano M, Schneggenburger R, Schirra C, Garaschuk O, Plant T, Konnerth A.

J Neurosci. 1996 Jan 15;16(2):456-66.

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