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Items: 8

1.

Gut and blood differ in constitutive blocks to HIV transcription, suggesting tissue-specific differences in the mechanisms that govern HIV latency.

Telwatte S, Lee S, Somsouk M, Hatano H, Baker C, Kaiser P, Kim P, Chen TH, Milush J, Hunt PW, Deeks SG, Wong JK, Yukl SA.

PLoS Pathog. 2018 Nov 15;14(11):e1007357. doi: 10.1371/journal.ppat.1007357. eCollection 2018 Nov.

2.

Molecular dissection of an inhibitor targeting the HIV integrase dependent preintegration complex nuclear import.

Wagstaff KM, Headey S, Telwatte S, Tyssen D, Hearps AC, Thomas DR, Tachedjian G, Jans DA.

Cell Microbiol. 2019 Jan;21(1):e12953. doi: 10.1111/cmi.12953. Epub 2018 Sep 27.

3.

HIV latency in isolated patient CD4+ T cells may be due to blocks in HIV transcriptional elongation, completion, and splicing.

Yukl SA, Kaiser P, Kim P, Telwatte S, Joshi SK, Vu M, Lampiris H, Wong JK.

Sci Transl Med. 2018 Feb 28;10(430). pii: eaap9927. doi: 10.1126/scitranslmed.aap9927.

4.

Differentiating Immune Cell Targets in Gut-Associated Lymphoid Tissue for HIV Cure.

Khan S, Telwatte S, Trapecar M, Yukl S, Sanjabi S.

AIDS Res Hum Retroviruses. 2017 Nov;33(S1):S40-S58. doi: 10.1089/AID.2017.0153. Review.

5.

An Optimized and Validated Method for Isolation and Characterization of Lymphocytes from HIV+ Human Gut Biopsies.

Trapecar M, Khan S, Roan NR, Chen TH, Telwatte S, Deswal M, Pao M, Somsouk M, Deeks SG, Hunt PW, Yukl S, Sanjabi S.

AIDS Res Hum Retroviruses. 2017 Nov;33(S1):S31-S39. doi: 10.1089/AID.2017.0208.

6.

Increasing prevalence of K65K and K66K in HIV-1 subtype B reverse transcriptase.

Telwatte S, Brumme CJ, Hearps AC, Latham CF, Hayward JA, Sonza S, Sluis-Cremer N, Harrigan PR, Tachedjian G.

AIDS. 2016 Nov 28;30(18):2787-2793.

PMID:
27677159
7.

Silent mutations at codons 65 and 66 in reverse transcriptase alleviate indel formation and restore fitness in subtype B HIV-1 containing D67N and K70R drug resistance mutations.

Telwatte S, Hearps AC, Johnson A, Latham CF, Moore K, Agius P, Tachedjian M, Sonza S, Sluis-Cremer N, Harrigan PR, Tachedjian G.

Nucleic Acids Res. 2015 Mar 31;43(6):3256-71. doi: 10.1093/nar/gkv128. Epub 2015 Mar 12.

8.

Virucidal activity of the dendrimer microbicide SPL7013 against HIV-1.

Telwatte S, Moore K, Johnson A, Tyssen D, Sterjovski J, Aldunate M, Gorry PR, Ramsland PA, Lewis GR, Paull JR, Sonza S, Tachedjian G.

Antiviral Res. 2011 Jun;90(3):195-9. doi: 10.1016/j.antiviral.2011.03.186. Epub 2011 Apr 1.

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