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Items: 23

1.

A Massively Parallel Selection of Small Molecule-RNA Motif Binding Partners Informs Design of an Antiviral from Sequence.

Childs-Disney JL, Tran T, Vummidi BR, Velagapudi SP, Haniff HS, Matsumoto Y, Crynen G, Southern MR, Biswas A, Wang ZF, Tellinghuisen TL, Disney MD.

Chem. 2018 Oct 11;4(10):2384-2404. doi: 10.1016/j.chempr.2018.08.003. Epub 2018 Sep 13.

2.

Transmission genetics of drug-resistant hepatitis C virus.

van Buuren N, Tellinghuisen TL, Richardson CD, Kirkegaard K.

Elife. 2018 Mar 28;7. pii: e32579. doi: 10.7554/eLife.32579.

3.

Interaction between Nonstructural Proteins NS4B and NS5A Is Essential for Proper NS5A Localization and Hepatitis C Virus RNA Replication.

Biswas A, Treadaway J, Tellinghuisen TL.

J Virol. 2016 Jul 27;90(16):7205-7218. doi: 10.1128/JVI.00037-16. Print 2016 Aug 15.

4.

A hepatitis C virus NS5A phosphorylation site that regulates RNA replication.

Lemay KL, Treadaway J, Angulo I, Tellinghuisen TL.

J Virol. 2013 Jan;87(2):1255-60. doi: 10.1128/JVI.02154-12. Epub 2012 Oct 31.

5.

Neutralizing antibody-resistant hepatitis C virus cell-to-cell transmission.

Brimacombe CL, Grove J, Meredith LW, Hu K, Syder AJ, Flores MV, Timpe JM, Krieger SE, Baumert TF, Tellinghuisen TL, Wong-Staal F, Balfe P, McKeating JA.

J Virol. 2011 Jan;85(1):596-605. doi: 10.1128/JVI.01592-10. Epub 2010 Oct 20.

6.

Development of novel therapies for hepatitis C.

Lemon SM, McKeating JA, Pietschmann T, Frick DN, Glenn JS, Tellinghuisen TL, Symons J, Furman PA.

Antiviral Res. 2010 Apr;86(1):79-92. doi: 10.1016/j.antiviral.2010.02.003. Review.

PMID:
20417376
7.

Molecular and contextual markers of hepatitis C virus and drug abuse.

Shapshak P, Somboonwit C, Drumright LN, Frost SD, Commins D, Tellinghuisen TL, Scott WK, Duncan R, McCoy C, Page JB, Giunta B, Fernandez F, Singer E, Levine A, Minagar A, Oluwadara O, Kotila T, Chiappelli F, Sinnott JT.

Mol Diagn Ther. 2009;13(3):153-79. doi: 10.2165/01250444-200913030-00002. Review.

8.

Reverse transcription PCR-based sequence analysis of hepatitis C virus replicon RNA.

Tellinghuisen TL, Lindenbach BD.

Methods Mol Biol. 2009;510:165-75. doi: 10.1007/978-1-59745-394-3_12.

PMID:
19009260
9.

Regulation of hepatitis C virion production via phosphorylation of the NS5A protein.

Tellinghuisen TL, Foss KL, Treadaway J.

PLoS Pathog. 2008 Mar 21;4(3):e1000032. doi: 10.1371/journal.ppat.1000032.

10.

Identification of residues required for RNA replication in domains II and III of the hepatitis C virus NS5A protein.

Tellinghuisen TL, Foss KL, Treadaway JC, Rice CM.

J Virol. 2008 Feb;82(3):1073-83. Epub 2007 Nov 21.

11.

Cellular cofactors affecting hepatitis C virus infection and replication.

Randall G, Panis M, Cooper JD, Tellinghuisen TL, Sukhodolets KE, Pfeffer S, Landthaler M, Landgraf P, Kan S, Lindenbach BD, Chien M, Weir DB, Russo JJ, Ju J, Brownstein MJ, Sheridan R, Sander C, Zavolan M, Tuschl T, Rice CM.

Proc Natl Acad Sci U S A. 2007 Jul 31;104(31):12884-9. Epub 2007 Jul 6.

12.

Studying hepatitis C virus: making the best of a bad virus.

Tellinghuisen TL, Evans MJ, von Hahn T, You S, Rice CM.

J Virol. 2007 Sep;81(17):8853-67. Epub 2007 May 23. Review. No abstract available.

14.

Complete replication of hepatitis C virus in cell culture.

Lindenbach BD, Evans MJ, Syder AJ, Wölk B, Tellinghuisen TL, Liu CC, Maruyama T, Hynes RO, Burton DR, McKeating JA, Rice CM.

Science. 2005 Jul 22;309(5734):623-6. Epub 2005 Jun 9.

15.

Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase.

Tellinghuisen TL, Marcotrigiano J, Rice CM.

Nature. 2005 May 19;435(7040):374-9.

16.

Association of sindbis virus capsid protein with phospholipid membranes and the E2 glycoprotein: implications for alphavirus assembly.

Wilkinson TA, Tellinghuisen TL, Kuhn RJ, Post CB.

Biochemistry. 2005 Mar 1;44(8):2800-10.

PMID:
15723524
17.

The NS5A protein of hepatitis C virus is a zinc metalloprotein.

Tellinghuisen TL, Marcotrigiano J, Gorbalenya AE, Rice CM.

J Biol Chem. 2004 Nov 19;279(47):48576-87. Epub 2004 Aug 31.

18.

Interaction between hepatitis C virus proteins and host cell factors.

Tellinghuisen TL, Rice CM.

Curr Opin Microbiol. 2002 Aug;5(4):419-27. Review.

PMID:
12160863
19.

Genetic and biochemical studies on the assembly of an enveloped virus.

Tellinghuisen TL, Perera R, Kuhn RJ.

Genet Eng (N Y). 2001;23:83-112. Review. No abstract available.

PMID:
11570108
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22.

Alphavirus nucleocapsid protein contains a putative coiled coil alpha-helix important for core assembly.

Perera R, Owen KE, Tellinghuisen TL, Gorbalenya AE, Kuhn RJ.

J Virol. 2001 Jan;75(1):1-10.

23.

In vitro assembly of alphavirus cores by using nucleocapsid protein expressed in Escherichia coli.

Tellinghuisen TL, Hamburger AE, Fisher BR, Ostendorp R, Kuhn RJ.

J Virol. 1999 Jul;73(7):5309-19.

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