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Items: 1 to 50 of 142

1.

The Protective Value of Maternal Group B Streptococcus Antibodies: Quantitative and Functional Analysis of Naturally Acquired Responses to Capsular Polysaccharides and Pilus Proteins in European Maternal Sera.

Fabbrini M, Rigat F, Rinaudo CD, Passalaqua I, Khacheh S, Creti R, Baldassarri L, Carboni F, Anderloni G, Rosini R, Maione D, Grandi G, Telford JL, Margarit I.

Clin Infect Dis. 2016 Sep 15;63(6):746-753. doi: 10.1093/cid/ciw377. Epub 2016 Jul 11.

PMID:
27402816
2.

Expression and Characterization of Recombinant, Tetrameric and Enzymatically Active Influenza Neuraminidase for the Setup of an Enzyme-Linked Lectin-Based Assay.

Prevato M, Ferlenghi I, Bonci A, Uematsu Y, Anselmi G, Giusti F, Bertholet S, Legay F, Telford JL, Settembre EC, Maione D, Cozzi R.

PLoS One. 2015 Aug 17;10(8):e0135474. doi: 10.1371/journal.pone.0135474. eCollection 2015.

3.

Corrigendum: Streptococcus agalactiae clones infecting humans were selected and fixed through the extensive use of tetracycline.

Da Cunha V, Davies MR, Douarre PE, Rosinski-Chupin I, Margarit I, Spinali S, Perkins T, Lechat P, Dmytruk N, Sauvage E, Ma L, Romi B, Tichit M, Lopez-Sanchez MJ, Descorps-Declere S, Souche E, Buchrieser C, Trieu-Cuot P, Moszer I, Clermont D, Maione D, Bouchier C, McMillan DJ, Parkhill J, Telford JL, Dougan G, Walker MJ, Holden MT, Poyart C, Glaser P.

Nat Commun. 2015 Jan 28;6:6108. doi: 10.1038/ncomms7108. No abstract available.

4.

Streptococcus agalactiae clones infecting humans were selected and fixed through the extensive use of tetracycline.

Da Cunha V, Davies MR, Douarre PE, Rosinski-Chupin I, Margarit I, Spinali S, Perkins T, Lechat P, Dmytruk N, Sauvage E, Ma L, Romi B, Tichit M, Lopez-Sanchez MJ, Descorps-Declere S, Souche E, Buchrieser C, Trieu-Cuot P, Moszer I, Clermont D, Maione D, Bouchier C, McMillan DJ, Parkhill J, Telford JL, Dougan G, Walker MJ; DEVANI Consortium, Holden MTG, Poyart C, Glaser P.

Nat Commun. 2014 Aug 4;5:4544. doi: 10.1038/ncomms5544. Erratum in: Nat Commun. 2015;6:6108.

5.

Acidic pH strongly enhances in vitro biofilm formation by a subset of hypervirulent ST-17 Streptococcus agalactiae strains.

D'Urzo N, Martinelli M, Pezzicoli A, De Cesare V, Pinto V, Margarit I, Telford JL, Maione D; Members of the DEVANI Study Group.

Appl Environ Microbiol. 2014 Apr;80(7):2176-85. doi: 10.1128/AEM.03627-13. Epub 2014 Jan 31.

6.

Understanding the molecular determinants driving the immunological specificity of the protective pilus 2a backbone protein of group B streptococcus.

Nuccitelli A, Rinaudo CD, Brogioni B, Cozzi R, Ferrer-Navarro M, Yero D, Telford JL, Grandi G, Daura X, Zacharias M, Maione D.

PLoS Comput Biol. 2013;9(6):e1003115. doi: 10.1371/journal.pcbi.1003115. Epub 2013 Jun 27.

7.

Group B Streptococcus pilus sortase regulation: a single mutation in the lid region induces pilin protein polymerization in vitro.

Cozzi R, Zerbini F, Assfalg M, D'Onofrio M, Biagini M, Martinelli M, Nuccitelli A, Norais N, Telford JL, Maione D, Rinaudo CD.

FASEB J. 2013 Aug;27(8):3144-54. doi: 10.1096/fj.13-227793. Epub 2013 Apr 30.

PMID:
23631841
8.

Adaptive response of Group B streptococcus to high glucose conditions: new insights on the CovRS regulation network.

Di Palo B, Rippa V, Santi I, Brettoni C, Muzzi A, Metruccio MM, Grifantini R, Telford JL, Paccani SR, Soriani M.

PLoS One. 2013 Apr 9;8(4):e61294. doi: 10.1371/journal.pone.0061294. Print 2013.

9.

High-level intracellular expression of heterologous proteins in Brevibacillus choshinensis SP3 under the control of a xylose inducible promoter.

D'Urzo N, Martinelli M, Nenci C, Brettoni C, Telford JL, Maione D.

Microb Cell Fact. 2013 Feb 1;12:12. doi: 10.1186/1475-2859-12-12.

10.

Capsular gene typing of Streptococcus agalactiae compared to serotyping by latex agglutination.

Yao K, Poulsen K, Maione D, Rinaudo CD, Baldassarri L, Telford JL, Sørensen UB; Members of the DEVANI Study Group, Kilian M.

J Clin Microbiol. 2013 Feb;51(2):503-7. doi: 10.1128/JCM.02417-12. Epub 2012 Nov 28.

11.

Structural basis for group B streptococcus pilus 1 sortases C regulation and specificity.

Cozzi R, Prigozhin D, Rosini R, Abate F, Bottomley MJ, Grandi G, Telford JL, Rinaudo CD, Maione D, Alber T.

PLoS One. 2012;7(11):e49048. doi: 10.1371/journal.pone.0049048. Epub 2012 Nov 8.

12.

Streptococcus pyogenes SpyCEP influences host-pathogen interactions during infection in a murine air pouch model.

Chiappini N, Seubert A, Telford JL, Grandi G, Serruto D, Margarit I, Janulczyk R.

PLoS One. 2012;7(7):e40411. doi: 10.1371/journal.pone.0040411. Epub 2012 Jul 27.

13.

Exogenous sialic acid transport contributes to group B streptococcus infection of mucosal surfaces.

Pezzicoli A, Ruggiero P, Amerighi F, Telford JL, Soriani M.

J Infect Dis. 2012 Sep 15;206(6):924-31. doi: 10.1093/infdis/jis451. Epub 2012 Jul 24.

PMID:
22829646
14.

Multi high-throughput approach for highly selective identification of vaccine candidates: the Group A Streptococcus case.

Bensi G, Mora M, Tuscano G, Biagini M, Chiarot E, Bombaci M, Capo S, Falugi F, Manetti AG, Donato P, Swennen E, Gallotta M, Garibaldi M, Pinto V, Chiappini N, Musser JM, Janulczyk R, Mariani M, Scarselli M, Telford JL, Grifantini R, Norais N, Margarit I, Grandi G.

Mol Cell Proteomics. 2012 Jun;11(6):M111.015693. doi: 10.1074/mcp.M111.015693. Epub 2012 Jan 27.

15.

New insights into the role of the glutamic acid of the E-box motif in group B Streptococcus pilus 2a assembly.

Cozzi R, Nuccitelli A, D'Onofrio M, Necchi F, Rosini R, Zerbini F, Biagini M, Norais N, Beier C, Telford JL, Grandi G, Assfalg M, Zacharias M, Maione D, Rinaudo CD.

FASEB J. 2012 May;26(5):2008-18. doi: 10.1096/fj.11-196378. Epub 2012 Jan 17.

PMID:
22253480
16.

Sortase A substrate specificity in GBS pilus 2a cell wall anchoring.

Necchi F, Nardi-Dei V, Biagini M, Assfalg M, Nuccitelli A, Cozzi R, Norais N, Telford JL, Rinaudo CD, Grandi G, Maione D.

PLoS One. 2011;6(10):e25300. doi: 10.1371/journal.pone.0025300. Epub 2011 Oct 4.

17.

Structure-based approach to rationally design a chimeric protein for an effective vaccine against Group B Streptococcus infections.

Nuccitelli A, Cozzi R, Gourlay LJ, Donnarumma D, Necchi F, Norais N, Telford JL, Rappuoli R, Bolognesi M, Maione D, Grandi G, Rinaudo CD.

Proc Natl Acad Sci U S A. 2011 Jun 21;108(25):10278-83. doi: 10.1073/pnas.1106590108. Epub 2011 May 18.

18.

Shigella targets T cells.

Telford JL, Baldari CT.

Cell Host Microbe. 2011 Apr 21;9(4):253-4. doi: 10.1016/j.chom.2011.04.003.

19.

Structure analysis and site-directed mutagenesis of defined key residues and motives for pilus-related sortase C1 in group B Streptococcus.

Cozzi R, Malito E, Nuccitelli A, D'Onofrio M, Martinelli M, Ferlenghi I, Grandi G, Telford JL, Maione D, Rinaudo CD.

FASEB J. 2011 Jun;25(6):1874-86. doi: 10.1096/fj.10-174797. Epub 2011 Feb 25.

PMID:
21357525
20.

Vacuolating Cytotoxin.

Atherton JC, Cover TL, Papini E, Telford JL.

In: Mobley HLT, Mendz GL, Hazell SL, editors. Helicobacter pylori: Physiology and Genetics. Washington (DC): ASM Press; 2001. Chapter 9.

21.

Protein Export.

Ilver D, Rappuoli R, Telford JL.

In: Mobley HLT, Mendz GL, Hazell SL, editors. Helicobacter pylori: Physiology and Genetics. Washington (DC): ASM Press; 2001. Chapter 19.

22.

Simple sequence repeats and genome plasticity in Streptococcus agalactiae.

Janulczyk R, Masignani V, Maione D, Tettelin H, Grandi G, Telford JL.

J Bacteriol. 2010 Aug;192(15):3990-4000. doi: 10.1128/JB.01465-09. Epub 2010 May 21.

23.

Relevance of pili in pathogenic streptococci pathogenesis and vaccine development.

Soriani M, Telford JL.

Future Microbiol. 2010 May;5(5):735-47. doi: 10.2217/fmb.10.37. Review.

PMID:
20441546
24.

Specific involvement of pilus type 2a in biofilm formation in group B Streptococcus.

Rinaudo CD, Rosini R, Galeotti CL, Berti F, Necchi F, Reguzzi V, Ghezzo C, Telford JL, Grandi G, Maione D.

PLoS One. 2010 Feb 15;5(2):e9216. doi: 10.1371/journal.pone.0009216.

25.

Genome-based approaches to vaccine development.

Mora M, Telford JL.

J Mol Med (Berl). 2010 Feb;88(2):143-7. doi: 10.1007/s00109-009-0574-9. Review.

PMID:
20066390
26.

Toll-like receptor 2 dependent immunogenicity of glycoconjugate vaccines containing chemically derived zwitterionic polysaccharides.

Gallorini S, Berti F, Mancuso G, Cozzi R, Tortoli M, Volpini G, Telford JL, Beninati C, Maione D, Wack A.

Proc Natl Acad Sci U S A. 2009 Oct 13;106(41):17481-6. doi: 10.1073/pnas.0903313106. Epub 2009 Sep 29.

27.

Vaccinology in the genome era.

Rinaudo CD, Telford JL, Rappuoli R, Seib KL.

J Clin Invest. 2009 Sep;119(9):2515-25. doi: 10.1172/JCI38330. Review.

28.

BibA induces opsonizing antibodies conferring in vivo protection against group B Streptococcus.

Santi I, Maione D, Galeotti CL, Grandi G, Telford JL, Soriani M.

J Infect Dis. 2009 Aug 15;200(4):564-70. doi: 10.1086/603540.

PMID:
19586417
29.

Surfome analysis as a fast track to vaccine discovery: identification of a novel protective antigen for Group B Streptococcus hypervirulent strain COH1.

Doro F, Liberatori S, Rodríguez-Ortega MJ, Rinaudo CD, Rosini R, Mora M, Scarselli M, Altindis E, D'Aurizio R, Stella M, Margarit I, Maione D, Telford JL, Norais N, Grandi G.

Mol Cell Proteomics. 2009 Jul;8(7):1728-37. doi: 10.1074/mcp.M800486-MCP200. Epub 2009 Apr 28.

30.

Preventing bacterial infections with pilus-based vaccines: the group B streptococcus paradigm.

Margarit I, Rinaudo CD, Galeotti CL, Maione D, Ghezzo C, Buttazzoni E, Rosini R, Runci Y, Mora M, Buccato S, Pagani M, Tresoldi E, Berardi A, Creti R, Baker CJ, Telford JL, Grandi G.

J Infect Dis. 2009 Jan 1;199(1):108-15. doi: 10.1086/595564.

PMID:
19086816
31.

Functional characterization of a newly identified group B Streptococcus pullulanase eliciting antibodies able to prevent alpha-glucans degradation.

Santi I, Pezzicoli A, Bosello M, Berti F, Mariani M, Telford JL, Grandi G, Soriani M.

PLoS One. 2008;3(11):e3787. doi: 10.1371/journal.pone.0003787. Epub 2008 Nov 21.

32.

Sequence variation in group A Streptococcus pili and association of pilus backbone types with lancefield T serotypes.

Falugi F, Zingaretti C, Pinto V, Mariani M, Amodeo L, Manetti AG, Capo S, Musser JM, Orefici G, Margarit I, Telford JL, Grandi G, Mora M.

J Infect Dis. 2008 Dec 15;198(12):1834-41. doi: 10.1086/593176.

PMID:
18928376
33.

Pilus backbone contributes to group B Streptococcus paracellular translocation through epithelial cells.

Pezzicoli A, Santi I, Lauer P, Rosini R, Rinaudo D, Grandi G, Telford JL, Soriani M.

J Infect Dis. 2008 Sep 15;198(6):890-8. doi: 10.1086/591182.

PMID:
18694342
34.

Sortase A utilizes an ancillary protein anchor for efficient cell wall anchoring of pili in Streptococcus agalactiae.

Nobbs AH, Rosini R, Rinaudo CD, Maione D, Grandi G, Telford JL.

Infect Immun. 2008 Aug;76(8):3550-60. doi: 10.1128/IAI.01613-07. Epub 2008 Jun 9.

35.

Bacterial genome variability and its impact on vaccine design.

Telford JL.

Cell Host Microbe. 2008 Jun 12;3(6):408-16. doi: 10.1016/j.chom.2008.05.004. Review.

36.

Scavenger receptor gp340 aggregates group A streptococci by binding pili.

Edwards AM, Manetti AG, Falugi F, Zingaretti C, Capo S, Buccato S, Bensi G, Telford JL, Margarit I, Grandi G.

Mol Microbiol. 2008 Jun;68(6):1378-94. doi: 10.1111/j.1365-2958.2008.06220.x. Epub 2008 Apr 29.

37.

Introduction of zwitterionic motifs into bacterial polysaccharides generates TLR2 agonists able to activate APCs.

Gallorini S, Berti F, Parente P, Baronio R, Aprea S, D'Oro U, Pizza M, Telford JL, Wack A.

J Immunol. 2007 Dec 15;179(12):8208-15.

38.

Mg(2+) signalling defines the group A streptococcal CsrRS (CovRS) regulon.

Gryllos I, Grifantini R, Colaprico A, Jiang S, Deforce E, Hakansson A, Telford JL, Grandi G, Wessels MR.

Mol Microbiol. 2007 Aug;65(3):671-83. Epub 2007 Jul 3.

39.

Streptococcus pyogenes pili promote pharyngeal cell adhesion and biofilm formation.

Manetti AG, Zingaretti C, Falugi F, Capo S, Bombaci M, Bagnoli F, Gambellini G, Bensi G, Mora M, Edwards AM, Musser JM, Graviss EA, Telford JL, Grandi G, Margarit I.

Mol Microbiol. 2007 May;64(4):968-83.

40.

Human gastric glycosphingolipids recognized by Helicobacter pylori vacuolating cytotoxin VacA.

Roche N, Ilver D, Angström J, Barone S, Telford JL, Teneberg S.

Microbes Infect. 2007 Apr;9(5):605-14. Epub 2007 Feb 20.

PMID:
17400502
41.

BibA: a novel immunogenic bacterial adhesin contributing to group B Streptococcus survival in human blood.

Santi I, Scarselli M, Mariani M, Pezzicoli A, Masignani V, Taddei A, Grandi G, Telford JL, Soriani M.

Mol Microbiol. 2007 Feb;63(3):754-67. Epub 2007 Jan 8.

42.

Transcriptional and proteomic profiles of group B Streptococcus type V reveal potential adherence proteins associated with high-level invasion.

Johri AK, Margarit I, Broenstrup M, Brettoni C, Hua L, Gygi SP, Telford JL, Grandi G, Paoletti LC.

Infect Immun. 2007 Mar;75(3):1473-83. Epub 2007 Jan 8.

43.

Use of Lactococcus lactis expressing pili from group B Streptococcus as a broad-coverage vaccine against streptococcal disease.

Buccato S, Maione D, Rinaudo CD, Volpini G, Taddei AR, Rosini R, Telford JL, Grandi G, Margarit I.

J Infect Dis. 2006 Aug 1;194(3):331-40. Epub 2006 Jun 30.

PMID:
16826481
44.

Identification of novel genomic islands coding for antigenic pilus-like structures in Streptococcus agalactiae.

Rosini R, Rinaudo CD, Soriani M, Lauer P, Mora M, Maione D, Taddei A, Santi I, Ghezzo C, Brettoni C, Buccato S, Margarit I, Grandi G, Telford JL.

Mol Microbiol. 2006 Jul;61(1):126-41.

45.

Pili in gram-positive pathogens.

Telford JL, Barocchi MA, Margarit I, Rappuoli R, Grandi G.

Nat Rev Microbiol. 2006 Jul;4(7):509-19. Review.

PMID:
16778837
46.

A Helicobacter pylori vacuolating toxin mutant that fails to oligomerize has a dominant negative phenotype.

Genisset C, Galeotti CL, Lupetti P, Mercati D, Skibinski DA, Barone S, Battistutta R, de Bernard M, Telford JL.

Infect Immun. 2006 Mar;74(3):1786-94.

47.

Characterization and identification of vaccine candidate proteins through analysis of the group A Streptococcus surface proteome.

Rodríguez-Ortega MJ, Norais N, Bensi G, Liberatori S, Capo S, Mora M, Scarselli M, Doro F, Ferrari G, Garaguso I, Maggi T, Neumann A, Covre A, Telford JL, Grandi G.

Nat Biotechnol. 2006 Feb;24(2):191-7. Epub 2006 Jan 15.

PMID:
16415855
49.

Group B Streptococcus crosses human epithelial cells by a paracellular route.

Soriani M, Santi I, Taddei A, Rappuoli R, Grandi G, Telford JL.

J Infect Dis. 2006 Jan 15;193(2):241-50. Epub 2005 Dec 9.

PMID:
16362888
50.

Group A Streptococcus produce pilus-like structures containing protective antigens and Lancefield T antigens.

Mora M, Bensi G, Capo S, Falugi F, Zingaretti C, Manetti AG, Maggi T, Taddei AR, Grandi G, Telford JL.

Proc Natl Acad Sci U S A. 2005 Oct 25;102(43):15641-6. Epub 2005 Oct 13.

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