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Items: 17

1.

DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation.

Godfrey L, Crump NT, Thorne R, Lau IJ, Repapi E, Dimou D, Smith AL, Harman JR, Telenius JM, Oudelaar AM, Downes DJ, Vyas P, Hughes JR, Milne TA.

Nat Commun. 2019 Jun 26;10(1):2803. doi: 10.1038/s41467-019-10844-3.

2.

High-Throughput Genotyping of CRISPR/Cas Edited Cells in 96-Well Plates.

Nussbaum L, Telenius JM, Hill S, Hirschfeld PP, Suciu MC; WIGWAM Consortium, Downes DJ, Hughes JR.

Methods Protoc. 2018 Aug 1;1(3). pii: E29. doi: 10.3390/mps1030029.

3.

Single-allele chromatin interactions identify regulatory hubs in dynamic compartmentalized domains.

Oudelaar AM, Davies JOJ, Hanssen LLP, Telenius JM, Schwessinger R, Liu Y, Brown JM, Downes DJ, Chiariello AM, Bianco S, Nicodemi M, Buckle VJ, Dekker J, Higgs DR, Hughes JR.

Nat Genet. 2018 Dec;50(12):1744-1751. doi: 10.1038/s41588-018-0253-2. Epub 2018 Oct 29.

4.

A tissue-specific self-interacting chromatin domain forms independently of enhancer-promoter interactions.

Brown JM, Roberts NA, Graham B, Waithe D, Lagerholm C, Telenius JM, De Ornellas S, Oudelaar AM, Scott C, Szczerbal I, Babbs C, Kassouf MT, Hughes JR, Higgs DR, Buckle VJ.

Nat Commun. 2018 Sep 21;9(1):3849. doi: 10.1038/s41467-018-06248-4.

5.

How to Tackle Challenging ChIP-Seq, with Long-Range Cross-Linking, Using ATRX as an Example.

Truch J, Telenius J, Higgs DR, Gibbons RJ.

Methods Mol Biol. 2018;1832:105-130. doi: 10.1007/978-1-4939-8663-7_6.

PMID:
30073524
6.

Sasquatch: predicting the impact of regulatory SNPs on transcription factor binding from cell- and tissue-specific DNase footprints.

Schwessinger R, Suciu MC, McGowan SJ, Telenius J, Taylor S, Higgs DR, Hughes JR.

Genome Res. 2017 Oct;27(10):1730-1742. doi: 10.1101/gr.220202.117. Epub 2017 Sep 13.

7.

Editing an α-globin enhancer in primary human hematopoietic stem cells as a treatment for β-thalassemia.

Mettananda S, Fisher CA, Hay D, Badat M, Quek L, Clark K, Hublitz P, Downes D, Kerry J, Gosden M, Telenius J, Sloane-Stanley JA, Faustino P, Coelho A, Doondeea J, Usukhbayar B, Sopp P, Sharpe JA, Hughes JR, Vyas P, Gibbons RJ, Higgs DR.

Nat Commun. 2017 Sep 4;8(1):424. doi: 10.1038/s41467-017-00479-7.

8.

DNA methylation of intragenic CpG islands depends on their transcriptional activity during differentiation and disease.

Jeziorska DM, Murray RJS, De Gobbi M, Gaentzsch R, Garrick D, Ayyub H, Chen T, Li E, Telenius J, Lynch M, Graham B, Smith AJH, Lund JN, Hughes JR, Higgs DR, Tufarelli C.

Proc Natl Acad Sci U S A. 2017 Sep 5;114(36):E7526-E7535. doi: 10.1073/pnas.1703087114. Epub 2017 Aug 21.

9.

Functional characterisation of cis-regulatory elements governing dynamic Eomes expression in the early mouse embryo.

Simon CS, Downes DJ, Gosden ME, Telenius J, Higgs DR, Hughes JR, Costello I, Bikoff EK, Robertson EJ.

Development. 2017 Apr 1;144(7):1249-1260. doi: 10.1242/dev.147322. Epub 2017 Feb 7.

10.

Genetic dissection of the α-globin super-enhancer in vivo.

Hay D, Hughes JR, Babbs C, Davies JOJ, Graham BJ, Hanssen L, Kassouf MT, Marieke Oudelaar AM, Sharpe JA, Suciu MC, Telenius J, Williams R, Rode C, Li PS, Pennacchio LA, Sloane-Stanley JA, Ayyub H, Butler S, Sauka-Spengler T, Gibbons RJ, Smith AJH, Wood WG, Higgs DR.

Nat Genet. 2016 Aug;48(8):895-903. doi: 10.1038/ng.3605. Epub 2016 Jul 4.

11.

Multiplexed analysis of chromosome conformation at vastly improved sensitivity.

Davies JO, Telenius JM, McGowan SJ, Roberts NA, Taylor S, Higgs DR, Hughes JR.

Nat Methods. 2016 Jan;13(1):74-80. doi: 10.1038/nmeth.3664. Epub 2015 Nov 23.

12.

Molecular dynamics simulations of the interactions of medicinal plant extracts and drugs with lipid bilayer membranes.

Kopeć W, Telenius J, Khandelia H.

FEBS J. 2013 Jun;280(12):2785-805. doi: 10.1111/febs.12286. Epub 2013 May 16. Review.

13.

Role of neutral lipids in tear fluid lipid layer: coarse-grained simulation study.

Telenius J, Koivuniemi A, Kulovesi P, Holopainen JM, Vattulainen I.

Langmuir. 2012 Dec 11;28(49):17092-100. doi: 10.1021/la304366d. Epub 2012 Nov 26.

PMID:
23151187
14.

Lessons from the biophysics of interfaces: lung surfactant and tear fluid.

Rantamäki AH, Telenius J, Koivuniemi A, Vattulainen I, Holopainen JM.

Prog Retin Eye Res. 2011 May;30(3):204-15. doi: 10.1016/j.preteyeres.2011.02.002. Epub 2011 Feb 23. Review.

PMID:
21352946
15.

Molecular organization of the tear fluid lipid layer.

Kulovesi P, Telenius J, Koivuniemi A, Brezesinski G, Rantamäki A, Viitala T, Puukilainen E, Ritala M, Wiedmer SK, Vattulainen I, Holopainen JM.

Biophys J. 2010 Oct 20;99(8):2559-67. doi: 10.1016/j.bpj.2010.08.001.

16.

Visualization of complex processes in lipid systems using computer simulations and molecular graphics.

Telenius J, Vattulainen I, Monticelli L.

Methods Mol Biol. 2009;580:317-38. doi: 10.1007/978-1-60761-325-1_18.

PMID:
19784608
17.

Structural basis of mechanochemical coupling in a hexameric molecular motor.

Kainov DE, Mancini EJ, Telenius J, Lísal J, Grimes JM, Bamford DH, Stuart DI, Tuma R.

J Biol Chem. 2008 Feb 8;283(6):3607-17. Epub 2007 Dec 5.

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