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Items: 21

1.

Development and Analytical Characterization of Pegunigalsidase Alfa, a Chemically Cross-Linked Plant Recombinant Human α-Galactosidase-A for Treatment of Fabry Disease.

Ruderfer I, Shulman A, Kizhner T, Azulay Y, Nataf Y, Tekoah Y, Shaaltiel Y.

Bioconjug Chem. 2018 May 16;29(5):1630-1639. doi: 10.1021/acs.bioconjchem.8b00133. Epub 2018 May 3.

PMID:
29698600
2.

Immunogenicity of glycans on biotherapeutic drugs produced in plant expression systems-The taliglucerase alfa story.

Rup B, Alon S, Amit-Cohen BC, Brill Almon E, Chertkoff R, Tekoah Y, Rudd PM.

PLoS One. 2017 Oct 31;12(10):e0186211. doi: 10.1371/journal.pone.0186211. eCollection 2017.

3.

Establishment of a tobacco BY2 cell line devoid of plant-specific xylose and fucose as a platform for the production of biotherapeutic proteins.

Hanania U, Ariel T, Tekoah Y, Fux L, Sheva M, Gubbay Y, Weiss M, Oz D, Azulay Y, Turbovski A, Forster Y, Shaaltiel Y.

Plant Biotechnol J. 2017 Sep;15(9):1120-1129. doi: 10.1111/pbi.12702. Epub 2017 Mar 3.

4.

Plant specific N-glycans do not have proven adverse effects in humans.

Shaaltiel Y, Tekoah Y.

Nat Biotechnol. 2016 Jul 12;34(7):706-8. doi: 10.1038/nbt.3556. No abstract available.

PMID:
27404878
5.

Insight into glucosidase II from the red marine microalga Porphyridium sp. (Rhodophyta).

Levy-Ontman O, Fisher M, Shotland Y, Tekoah Y, Malis Arad S.

J Phycol. 2015 Dec;51(6):1075-87. doi: 10.1111/jpy.12341. Epub 2015 Sep 13.

PMID:
26987003
6.

Large-scale production of pharmaceutical proteins in plant cell culture-the Protalix experience.

Tekoah Y, Shulman A, Kizhner T, Ruderfer I, Fux L, Nataf Y, Bartfeld D, Ariel T, Gingis-Velitski S, Hanania U, Shaaltiel Y.

Plant Biotechnol J. 2015 Oct;13(8):1199-208. doi: 10.1111/pbi.12428. Epub 2015 Jun 23. Review.

7.

Plant-based oral delivery of β-glucocerebrosidase as an enzyme replacement therapy for Gaucher's disease.

Shaaltiel Y, Gingis-Velitski S, Tzaban S, Fiks N, Tekoah Y, Aviezer D.

Plant Biotechnol J. 2015 Oct;13(8):1033-40. doi: 10.1111/pbi.12366. Epub 2015 Apr 1.

8.

Characterization of a chemically modified plant cell culture expressed human α-Galactosidase-A enzyme for treatment of Fabry disease.

Kizhner T, Azulay Y, Hainrichson M, Tekoah Y, Arvatz G, Shulman A, Ruderfer I, Aviezer D, Shaaltiel Y.

Mol Genet Metab. 2015 Feb;114(2):259-67. doi: 10.1016/j.ymgme.2014.08.002. Epub 2014 Aug 10.

9.

Genes involved in the endoplasmic reticulum N-glycosylation pathway of the red microalga Porphyridium sp.: a bioinformatic study.

Levy-Ontman O, Fisher M, Shotland Y, Weinstein Y, Tekoah Y, Arad SM.

Int J Mol Sci. 2014 Feb 7;15(2):2305-26. doi: 10.3390/ijms15022305.

10.

Glycosylation and functionality of recombinant β-glucocerebrosidase from various production systems.

Tekoah Y, Tzaban S, Kizhner T, Hainrichson M, Gantman A, Golembo M, Aviezer D, Shaaltiel Y.

Biosci Rep. 2013 Sep 25;33(5). pii: e00071. doi: 10.1042/BSR20130081.

11.

Unique N-glycan moieties of the 66-kDa cell wall glycoprotein from the red microalga Porphyridium sp.

Levy-Ontman O, Arad SM, Harvey DJ, Parsons TB, Fairbanks A, Tekoah Y.

J Biol Chem. 2011 Jun 17;286(24):21340-52. doi: 10.1074/jbc.M110.175042. Epub 2011 Apr 22.

12.

Serum apolipoproteins C-I and C-III are reduced in stomach cancer patients: results from MALDI-based peptidome and immuno-based clinical assays.

Cohen M, Yossef R, Erez T, Kugel A, Welt M, Karpasas MM, Bones J, Rudd PM, Taieb J, Boissin H, Harats D, Noy K, Tekoah Y, Lichtenstein RG, Rubin E, Porgador A.

PLoS One. 2011 Jan 18;6(1):e14540. doi: 10.1371/journal.pone.0014540.

13.

A pivotal role for the Streptococcus iniae extracellular polysaccharide in triggering proinflammatory cytokines transcription and inducing death in rainbow trout.

Eyngor M, Lublin A, Shapira R, Hurvitz A, Zlotkin A, Tekoah Y, Eldar A.

FEMS Microbiol Lett. 2010 Apr;305(2):109-20. doi: 10.1111/j.1574-6968.2010.01919.x. Epub 2010 Feb 3.

14.

NKp46 O-glycan sequences that are involved in the interaction with hemagglutinin type 1 of influenza virus.

Mendelson M, Tekoah Y, Zilka A, Gershoni-Yahalom O, Gazit R, Achdout H, Bovin NV, Meningher T, Mandelboim M, Mandelboim O, David A, Porgador A.

J Virol. 2010 Apr;84(8):3789-97. doi: 10.1128/JVI.01815-09. Epub 2010 Feb 10.

15.

Chemical characterization, antiproliferative and antiadhesive properties of polysaccharides extracted from Pleurotus pulmonarius mycelium and fruiting bodies.

Lavi I, Levinson D, Peri I, Tekoah Y, Hadar Y, Schwartz B.

Appl Microbiol Biotechnol. 2010 Feb;85(6):1977-90. doi: 10.1007/s00253-009-2296-x. Epub 2009 Oct 15.

PMID:
19830415
16.

Isolation and characterization of poly- and oligosaccharides from the red microalga Porphyridium sp.

Geresh S, Arad SM, Levy-Ontman O, Zhang W, Tekoah Y, Glaser R.

Carbohydr Res. 2009 Feb 17;344(3):343-9. doi: 10.1016/j.carres.2008.11.012. Epub 2008 Dec 6.

PMID:
19131048
17.

Emergence of novel Streptococcus iniae exopolysaccharide-producing strains following vaccination with nonproducing strains.

Eyngor M, Tekoah Y, Shapira R, Hurvitz A, Zlotkin A, Lublin A, Eldar A.

Appl Environ Microbiol. 2008 Nov;74(22):6892-7. doi: 10.1128/AEM.00853-08. Epub 2008 Sep 19.

18.

Altered glycosylation of recombinant NKp30 hampers binding to heparan sulfate: a lesson for the use of recombinant immunoreceptors as an immunological tool.

Hershkovitz O, Jarahian M, Zilka A, Bar-Ilan A, Landau G, Jivov S, Tekoah Y, Glicklis R, Gallagher JT, Hoffmann SC, Zer H, Mandelboim O, Watzl C, Momburg F, Porgador A.

Glycobiology. 2008 Jan;18(1):28-41. Epub 2007 Nov 15.

PMID:
18006589
19.

Effect of organic and inorganic nitrogenous compounds on RDX degradation and cytochrome P-450 expression in Rhodococcus strain YH1.

Nejidat A, Kafka L, Tekoah Y, Ronen Z.

Biodegradation. 2008 Jun;19(3):313-20. Epub 2007 Jul 5.

PMID:
17611801
20.

Controlled glycosylation of therapeutic antibodies in plants.

Tekoah Y, Ko K, Koprowski H, Harvey DJ, Wormald MR, Dwek RA, Rudd PM.

Arch Biochem Biophys. 2004 Jun 15;426(2):266-78.

PMID:
15158677
21.

Function and glycosylation of plant-derived antiviral monoclonal antibody.

Ko K, Tekoah Y, Rudd PM, Harvey DJ, Dwek RA, Spitsin S, Hanlon CA, Rupprecht C, Dietzschold B, Golovkin M, Koprowski H.

Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):8013-8. Epub 2003 Jun 10.

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