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HPV33+ HNSCC is associated with poor prognosis and has unique genomic and immunologic landscapes.

Chatfield-Reed K, Gui S, O'Neill WQ, Teknos TN, Pan Q.

Oral Oncol. 2019 Dec 10;100:104488. doi: 10.1016/j.oraloncology.2019.104488. [Epub ahead of print]


A Phase I/II Trial of Cetuximab in Combination with Interleukin-12 Administered to Patients with Unresectable Primary or Recurrent Head and Neck Squamous Cell Carcinoma.

McMichael EL, Benner B, Atwal LS, Courtney NB, Mo X, Davis ME, Campbell AR, Duggan MC, Williams K, Martin K, Levine K, Olaverria Salavaggione GN, Noel T, Ganju A, Uppati S, Paul B, Olencki T, Teknos TN, Savvides P, Tridandapani S, Byrd JC, Caligiuri MA, Liu SV, Carson WE 3rd.

Clin Cancer Res. 2019 Aug 15;25(16):4955-4965. doi: 10.1158/1078-0432.CCR-18-2108. Epub 2019 May 29.


LCL161, a SMAC-mimetic, Preferentially Radiosensitizes Human Papillomavirus-negative Head and Neck Squamous Cell Carcinoma.

Yang L, Kumar B, Shen C, Zhao S, Blakaj D, Li T, Romito M, Teknos TN, Williams TM.

Mol Cancer Ther. 2019 Jun;18(6):1025-1035. doi: 10.1158/1535-7163.MCT-18-1157. Epub 2019 Apr 23.


Risk Factors Associated With Postoperative Delirium in Patients Undergoing Head and Neck Free Flap Reconstruction.

Densky J, Eskander A, Kang S, Chan J, Tweel B, Sitapara J, Ozer E, Agrawal A, Carrau R, Rocco J, Teknos TN, Old M.

JAMA Otolaryngol Head Neck Surg. 2019 Mar 1;145(3):216-221. doi: 10.1001/jamaoto.2018.3820. Erratum in: JAMA Otolaryngol Head Neck Surg. 2019 Feb 28;:.


A phase 1 trial of Vorinostat in combination with concurrent chemoradiation therapy in the treatment of advanced staged head and neck squamous cell carcinoma.

Teknos TN, Grecula J, Agrawal A, Old MO, Ozer E, Carrau R, Kang S, Rocco J, Blakaj D, Diavolitsis V, Kumar B, Kumar P, Pan Q, Palettas M, Wei L, Baiocchi R, Savvides P.

Invest New Drugs. 2019 Aug;37(4):702-710. doi: 10.1007/s10637-018-0696-4. Epub 2018 Dec 19.


Predictors of gastrostomy tube dependence in surgically managed oropharyngeal squamous cell carcinoma.

Varma VR, Eskander A, Kang SY, Kumar B, Brown NV, Zhao S, Brock G, Agrawal A, Carrau RL, Old MO, Ozer E, Rocco JW, Schuller DE, Dziegielewski PT, Cipolla MJ, Teknos TN.

Laryngoscope. 2019 Feb;129(2):415-421. doi: 10.1002/lary.27290. Epub 2018 Sep 8.


The unique and valuable soft tissue free flap in head and neck reconstruction: Lateral arm.

Kang SY, Eskander A, Patel K, Teknos TN, Old MO.

Oral Oncol. 2018 Jul;82:100-107. doi: 10.1016/j.oraloncology.2018.05.006. Epub 2018 May 21.


Predictors of Complications in Patients Receiving Head and Neck Free Flap Reconstructive Procedures.

Eskander A, Kang S, Tweel B, Sitapara J, Old M, Ozer E, Agrawal A, Carrau R, Rocco JW, Teknos TN.

Otolaryngol Head Neck Surg. 2018 May;158(5):839-847. doi: 10.1177/0194599818757949. Epub 2018 Apr 3.


Supine positioning for the subscapular system of flaps: A pictorial essay.

Eskander A, Kang SY, Ozer E, Agrawal A, Carrau R, Rocco JW, Teknos TN, Old MO.

Head Neck. 2018 May;40(5):1068-1072. doi: 10.1002/hed.25051. Epub 2018 Feb 27. Review.


Salvage skull base reconstruction in the endoscopic era: Vastus lateralis free tissue transfer.

Kang SY, Eskander A, Hachem RA, Ozer E, Teknos TN, Old MO, Prevedello DM, Carrau RL.

Head Neck. 2018 Apr;40(4):E45-E52. doi: 10.1002/hed.25094. Epub 2018 Feb 6.


Quality Indicators: Measurement and Predictors in Head and Neck Cancer Free Flap Patients.

Eskander A, Kang SY, Tweel B, Sitapara J, Old M, Ozer E, Agrawal A, Carrau R, Rocco J, Teknos TN.

Otolaryngol Head Neck Surg. 2018 Feb;158(2):265-272. doi: 10.1177/0194599817742373. Epub 2018 Jan 2.


Appraisal of the AJCC 8th edition pathologic staging modifications for HPV-positive oropharyngeal cancer, a study of the National Cancer Data Base.

Zhan KY, Eskander A, Kang SY, Old MO, Ozer E, Agrawal AA, Carrau RL, Rocco JW, Teknos TN.

Oral Oncol. 2017 Oct;73:152-159. doi: 10.1016/j.oraloncology.2017.08.020. Epub 2017 Sep 7.


Transoral robotic surgery for tonsillar cancer: Addressing the contralateral tonsil.

Dziegielewski PT, Boyce BJ, Old M, Teknos TN, Agrawal A, Patwa H, Ozer E.

Head Neck. 2017 Nov;39(11):2224-2231. doi: 10.1002/hed.24887. Epub 2017 Aug 7.


Quality of life outcomes of transoral robotic surgery with or without adjuvant therapy for oropharyngeal cancer.

Sethia R, Yumusakhuylu AC, Ozbay I, Diavolitsis V, Brown NV, Zhao S, Wei L, Old M, Agrawal A, Teknos TN, Ozer E.

Laryngoscope. 2018 Feb;128(2):403-411. doi: 10.1002/lary.26796. Epub 2017 Aug 3.


A muscle-specific protein 'myoferlin' modulates IL-6/STAT3 signaling by chaperoning activated STAT3 to nucleus.

Yadav A, Kumar B, Lang JC, Teknos TN, Kumar P.

Oncogene. 2017 Nov 16;36(46):6374-6382. doi: 10.1038/onc.2017.245. Epub 2017 Jul 24.


Advances in midface reconstruction: beyond the reconstructive ladder.

Eskander A, Kang SY, Teknos TN, Old MO.

Curr Opin Otolaryngol Head Neck Surg. 2017 Oct;25(5):422-430. doi: 10.1097/MOO.0000000000000396. Review.


Digital otoscopy versus microscopy: How correct and confident are ear experts in their diagnoses?

Moberly AC, Zhang M, Yu L, Gurcan M, Senaras C, Teknos TN, Elmaraghy CA, Taj-Schaal N, Essig GF.

J Telemed Telecare. 2018 Aug;24(7):453-459. doi: 10.1177/1357633X17708531. Epub 2017 May 8.


DEK associates with tumor stage and outcome in HPV16 positive oropharyngeal squamous cell carcinoma.

Smith EA, Kumar B, Komurov K, Smith SM, Brown NV, Zhao S, Kumar P, Teknos TN, Wells SI.

Oncotarget. 2017 Apr 4;8(14):23414-23426. doi: 10.18632/oncotarget.15582.


NUT Midline Carcinoma of the Sublingual Gland: Clinical Presentation and Review.

Seim NB, Philips RHW, Schoenfield L, Teknos TN, Rocco JW, Agrawal A, Ozer E, Carrau RL, Kang SY, Old MO.

Head Neck Pathol. 2017 Dec;11(4):460-468. doi: 10.1007/s12105-017-0809-y. Epub 2017 Mar 27. Review.


Notch1 Overexpression Correlates to Improved Survival in Cancer of the Oropharynx.

Kaka AS, Nowacki NB, Kumar B, Zhao S, Old MO, Agrawal A, Ozer E, Carrau RL, Schuller DE, Kumar P, Teknos TN.

Otolaryngol Head Neck Surg. 2017 Apr;156(4):652-659. doi: 10.1177/0194599816688178. Epub 2017 Feb 14.


Lateral arm free tissue transfer for parotid reconstruction: A pictorial essay.

Kang SY, Old MO, Teknos TN.

Head Neck. 2017 May;39(5):1015-1019. doi: 10.1002/hed.24695. Epub 2017 Feb 7.


Survival Rates Using Individualized Bioselection Treatment Methods in Patients With Advanced Laryngeal Cancer.

Wolf GT, Bellile E, Eisbruch A, Urba S, Bradford CR, Peterson L, Prince ME, Teknos TN, Chepeha DB, Hogikyan ND, McLean SA, Moyer J, Taylor JMG, Worden FP.

JAMA Otolaryngol Head Neck Surg. 2017 Apr 1;143(4):355-366. doi: 10.1001/jamaoto.2016.3669.


Nuclear PRMT5, cyclin D1 and IL-6 are associated with poor outcome in oropharyngeal squamous cell carcinoma patients and is inversely associated with p16-status.

Kumar B, Yadav A, Brown NV, Zhao S, Cipolla MJ, Wakely PE, Schmitt AC, Baiocchi RA, Teknos TN, Old M, Kumar P.

Oncotarget. 2017 Feb 28;8(9):14847-14859. doi: 10.18632/oncotarget.14682.


Personalized Medicine Approach for an Exceptional Response to Multiple-recurrent and Metastatic HER2-positive Oropharyngeal Squamous Cell Carcinoma.

Seim NB, Kang SY, Bhandari M, Jones RG, Teknos TN.

Ann Otol Rhinol Laryngol. 2017 Apr;126(4):334-339. doi: 10.1177/0003489416687309. Epub 2017 Jan 6.


Differential mutation frequencies in metastatic cutaneous squamous cell carcinomas versus primary tumors.

Yilmaz AS, Ozer HG, Gillespie JL, Allain DC, Bernhardt MN, Furlan KC, Castro LT, Peters SB, Nagarajan P, Kang SY, Iwenofu OH, Olencki T, Teknos TN, Toland AE.

Cancer. 2017 Apr 1;123(7):1184-1193. doi: 10.1002/cncr.30459. Epub 2016 Dec 1.


Bazedoxifene enhances the anti-tumor effects of cisplatin and radiation treatment by blocking IL-6 signaling in head and neck cancer.

Yadav A, Kumar B, Teknos TN, Kumar P.

Oncotarget. 2016 Aug 22;8(40):66912-66924. doi: 10.18632/oncotarget.11464. eCollection 2017 Sep 15.


Hypoxic repression of pyruvate dehydrogenase activity is necessary for metabolic reprogramming and growth of model tumours.

Golias T, Papandreou I, Sun R, Kumar B, Brown NV, Swanson BJ, Pai R, Jaitin D, Le QT, Teknos TN, Denko NC.

Sci Rep. 2016 Aug 8;6:31146. doi: 10.1038/srep31146.


Novel therapeutics and emerging technologies in head and neck cancer.

Teknos TN.

World J Otorhinolaryngol Head Neck Surg. 2016 Jul 25;2(2):59. doi: 10.1016/j.wjorl.2016.06.001. eCollection 2016 Jun. No abstract available.


Interleukin-6 role in head and neck squamous cell carcinoma progression.

Choudhary MM, France TJ, Teknos TN, Kumar P.

World J Otorhinolaryngol Head Neck Surg. 2016 Jul 20;2(2):90-97. doi: 10.1016/j.wjorl.2016.05.002. eCollection 2016 Jun. Review.


TriCurin, a novel formulation of curcumin, epicatechin gallate, and resveratrol, inhibits the tumorigenicity of human papillomavirus-positive head and neck squamous cell carcinoma.

Piao L, Mukherjee S, Chang Q, Xie X, Li H, Castellanos MR, Banerjee P, Iqbal H, Ivancic R, Wang X, Teknos TN, Pan Q.

Oncotarget. 2016 Jul 16;8(36):60025-60035. doi: 10.18632/oncotarget.10620. eCollection 2017 Sep 1.


Effect of surgical intervention on circulating tumor cells in patients with squamous cell carcinoma of the head and neck using a negative enrichment technology.

Jatana KR, Balasubramanian P, McMullen KP, Lang JC, Teknos TN, Chalmers JJ.

Head Neck. 2016 Dec;38(12):1799-1803. doi: 10.1002/hed.24519. Epub 2016 Jun 5.


Suberoylanilide hydroxamic acid inhibits growth of head and neck cancer cell lines by reactivation of tumor suppressor microRNAs.

Datta J, Islam M, Dutta S, Roy S, Pan Q, Teknos TN.

Oral Oncol. 2016 May;56:32-9. doi: 10.1016/j.oraloncology.2016.02.015. Epub 2016 Mar 19.


Contour and osteotomy of free fibula transplant using a ruler template.

Kang SY, Old MO, Teknos TN.

Laryngoscope. 2016 Oct;126(10):2288-90. doi: 10.1002/lary.25925. Epub 2016 Mar 12.


High expression of myoferlin is associated with poor outcome in oropharyngeal squamous cell carcinoma patients and is inversely associated with HPV-status.

Kumar B, Brown NV, Swanson BJ, Schmitt AC, Old M, Ozer E, Agrawal A, Schuller DE, Teknos TN, Kumar P.

Oncotarget. 2016 Apr 5;7(14):18665-77. doi: 10.18632/oncotarget.7625.


Diagnostic Challenges in the Fine Needle Aspiration Biopsy of Chronic Sclerosing Sialadenitis (Küttner's Tumor) in the Context of Head and Neck Malignancy: A Series of 4 Cases.

Leon ME, Santosh N, Agarwal A, Teknos TN, Ozer E, Iwenofu OH.

Head Neck Pathol. 2016 Sep;10(3):389-93. doi: 10.1007/s12105-016-0701-1. Epub 2016 Feb 24.


Surgical management of oropharyngeal squamous cell carcinoma: Survival and functional outcomes.

Kumar B, Cipolla MJ, Old MO, Brown NV, Kang SY, Dziegielewski PT, Durmus K, Ozer E, Agrawal A, Carrau RL, Schuller DE, Leon ME, Pan Q, Kumar P, Wood V, Burgers J, Wakely PE Jr, Teknos TN.

Head Neck. 2016 Apr;38 Suppl 1:E1794-802. doi: 10.1002/hed.24319. Epub 2015 Dec 23.


Tumor-Associated Endothelial Cells Promote Tumor Metastasis by Chaperoning Circulating Tumor Cells and Protecting Them from Anoikis.

Yadav A, Kumar B, Yu JG, Old M, Teknos TN, Kumar P.

PLoS One. 2015 Oct 28;10(10):e0141602. doi: 10.1371/journal.pone.0141602. eCollection 2015.


miR-124 Regulates the Epithelial-Restricted with Serine Box/Epidermal Growth Factor Receptor Signaling Axis in Head and Neck Squamous Cell Carcinoma.

Zhang M, Piao L, Datta J, Lang JC, Xie X, Teknos TN, Mapp AK, Pan Q.

Mol Cancer Ther. 2015 Oct;14(10):2313-20. doi: 10.1158/1535-7163.MCT-14-1071. Epub 2015 Jul 30.


Safety and efficacy of concurrent neck dissection and transoral robotic surgery.

Kucur C, Durmus K, Gun R, Old MO, Agrawal A, Teknos TN, Ozer E.

Head Neck. 2016 Apr;38 Suppl 1:E519-23. doi: 10.1002/hed.24033. Epub 2015 Jul 6.


MicroRNA expression profiling in metastatic cutaneous squamous cell carcinoma.

Gillespie J, Skeeles LE, Allain DC, Kent MN, Peters SB, Nagarajan P, Yu L, Teknos TN, Olencki T, Toland AE.

J Eur Acad Dermatol Venereol. 2016 Jun;30(6):1043-5. doi: 10.1111/jdv.13098. Epub 2015 Mar 12. No abstract available.


Predictors and costs of readmissions at an academic head and neck surgery service.

Dziegielewski PT, Boyce B, Manning A, Agrawal A, Old M, Ozer E, Teknos TN.

Head Neck. 2016 Apr;38 Suppl 1:E502-10. doi: 10.1002/hed.24030. Epub 2015 Aug 25.


The impact of cancer treatment on the diets and food preferences of patients receiving outpatient treatment.

Coa KI, Epstein JB, Ettinger D, Jatoi A, McManus K, Platek ME, Price W, Stewart M, Teknos TN, Moskowitz B.

Nutr Cancer. 2015;67(2):339-53. doi: 10.1080/01635581.2015.990577. Epub 2015 Feb 9.


Management of complications and compromised free flaps following major head and neck surgery.

Kucur C, Durmus K, Uysal IO, Old M, Agrawal A, Arshad H, Teknos TN, Ozer E.

Eur Arch Otorhinolaryngol. 2016 Jan;273(1):209-13. doi: 10.1007/s00405-014-3489-1. Epub 2015 Jan 10.


ATN-224 enhances antitumor efficacy of oncolytic herpes virus against both local and metastatic head and neck squamous cell carcinoma.

Yoo JY, Yu JG, Kaka A, Pan Q, Kumar P, Kumar B, Zhang J, Mazar A, Teknos TN, Kaur B, Old MO.

Mol Ther Oncolytics. 2015 May 20;2:15008. doi: 10.1038/mto.2015.8. eCollection 2015.


Salivary gland cancer in BRCA-positive families: a retrospective review.

Shen TK, Teknos TN, Toland AE, Senter L, Nagy R.

JAMA Otolaryngol Head Neck Surg. 2014 Dec;140(12):1213-7. doi: 10.1001/jamaoto.2014.1998.


How often parapharyngeal space is encountered in TORS oropharynx cancer resection.

Kucur C, Durmus K, Teknos TN, Ozer E.

Eur Arch Otorhinolaryngol. 2015 Sep;272(9):2521-6. doi: 10.1007/s00405-014-3251-8. Epub 2014 Aug 21.


Are all cancer stem cells created equal?

Xie X, Teknos TN, Pan Q.

Stem Cells Transl Med. 2014 Oct;3(10):1111-5. doi: 10.5966/sctm.2014-0085. Epub 2014 Aug 13. Review.


Does body mass index matter while selecting the flap type for pharyngeal reconstructions?

Calli C, Teknos TN, Agrawal A, Schuller DE, Ozer E, Songu M.

J Craniofac Surg. 2014 May;25(3):780-2. doi: 10.1097/SCS.0000000000000827.


Functional and quality-of-life outcomes of transoral robotic surgery for carcinoma of unknown primary.

Durmus K, Patwa HS, Gokozan HN, Kucur C, Teknos TN, Agrawal A, Old MO, Ozer E.

Laryngoscope. 2014 Sep;124(9):2089-95. doi: 10.1002/lary.24705. Epub 2014 May 2.

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