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Nitrite Improves Heart Regeneration in Zebrafish.

Rochon ER, Missinato MA, Xue J, Tejero J, Tsang M, Gladwin MT, Corti P.

Antioxid Redox Signal. 2019 Dec 12. doi: 10.1089/ars.2018.7687. [Epub ahead of print]


The Châtelperronian Neanderthals of Cova Foradada (Calafell, Spain) used imperial eagle phalanges for symbolic purposes.

Rodríguez-Hidalgo A, Morales JI, Cebrià A, Courtenay LA, Fernández-Marchena JL, García-Argudo G, Marín J, Saladié P, Soto M, Tejero JM, Fullola JM.

Sci Adv. 2019 Nov 1;5(11):eaax1984. doi: 10.1126/sciadv.aax1984. eCollection 2019 Nov.


Carbonic Anhydrase II Does Not Regulate Nitrite Dependent Nitric Oxide Formation and Vasodilation.

Wang L, Sparacino-Watkins CE, Wang J, Wajih N, Varano P, Xu Q, Cecco E, Tejero J, Soleimani M, Kim-Shapiro DB, Gladwin MT.

Br J Pharmacol. 2019 Oct 28. doi: 10.1111/bph.14887. [Epub ahead of print]


The Zebrafish Cytochrome b5/Cytochrome b5 Reductase/NADH System Efficiently Reduces Cytoglobins 1 and 2: Conserved Activity of Cytochrome b5/Cytochrome b5 Reductases during Vertebrate Evolution.

Amdahl MB, Petersen EE, Bocian K, Kaliszuk SJ, DeMartino AW, Tiwari S, Sparacino-Watkins CE, Corti P, Rose JJ, Gladwin MT, Fago A, Tejero J.

Biochemistry. 2019 Jul 23;58(29):3212-3223. doi: 10.1021/acs.biochem.9b00406. Epub 2019 Jul 10.


The Middle-to-Upper Paleolithic transition occupations from Cova Foradada (Calafell, NE Iberia).

Morales JI, Cebrià A, Burguet-Coca A, Fernández-Marchena JL, García-Argudo G, Rodríguez-Hidalgo A, Soto M, Talamo S, Tejero JM, Vallverdú J, Fullola JM.

PLoS One. 2019 May 16;14(5):e0215832. doi: 10.1371/journal.pone.0215832. eCollection 2019.


Mechanism and regulation of ferrous heme-nitric oxide (NO) oxidation in NO synthases.

Tejero J, Hunt AP, Santolini J, Lehnert N, Stuehr DJ.

J Biol Chem. 2019 May 10;294(19):7904-7916. doi: 10.1074/jbc.RA119.007810. Epub 2019 Mar 29.


Sources of Vascular Nitric Oxide and Reactive Oxygen Species and Their Regulation

Tejero J, Shiva S, Gladwin MT.

Physiol Rev. 2019 Jan 1;99(1):311-379. doi: 10.1152/physrev.00036.2017. Review.


Nitrosyl Myoglobins and Their Nitrite Precursors: Crystal Structural and Quantum Mechanics and Molecular Mechanics Theoretical Investigations of Preferred Fe -NO Ligand Orientations in Myoglobin Distal Pockets.

Wang B, Shi Y, Tejero J, Powell SM, Thomas LM, Gladwin MT, Shiva S, Zhang Y, Richter-Addo GB.

Biochemistry. 2018 Aug 14;57(32):4788-4802. doi: 10.1021/acs.biochem.8b00542. Epub 2018 Jul 27.


Cigarette smoke extract acts directly on CD4 T cells to enhance Th1 polarization and reduce memory potential.

Tejero JD, Armand NC, Finn CM, Dhume K, Strutt TM, Chai KX, Chen LM, McKinstry KK.

Cell Immunol. 2018 Sep;331:121-129. doi: 10.1016/j.cellimm.2018.06.005. Epub 2018 Jun 18.


Symbolic emblems of the Levantine Aurignacians as a regional entity identifier (Hayonim Cave, Lower Galilee, Israel).

Tejero JM, Belfer-Cohen A, Bar-Yosef O, Gutkin V, Rabinovich R.

Proc Natl Acad Sci U S A. 2018 May 15;115(20):5145-5150. doi: 10.1073/pnas.1717145115. Epub 2018 Apr 30.


Detection of human cytomegalovirus in bronchoalveolar lavage of intensive care unit patients.

Vergara A, Cilloniz C, Luque N, Garcia-Vidal C, Tejero J, Perelló R, Lucena CM, Torres A, Marcos MA.

Eur Respir J. 2018 Feb 7;51(2). pii: 1701332. doi: 10.1183/13993003.01332-2017. Print 2018 Feb. No abstract available.


Thrombospondin-1 protects against pathogen-induced lung injury by limiting extracellular matrix proteolysis.

Qu Y, Olonisakin T, Bain W, Zupetic J, Brown R, Hulver M, Xiong Z, Tejero J, Shanks RM, Bomberger JM, Cooper VS, Zegans ME, Ryu H, Han J, Pilewski J, Ray A, Cheng Z, Ray P, Lee JS.

JCI Insight. 2018 Feb 8;3(3). pii: 96914. doi: 10.1172/jci.insight.96914. eCollection 2018 Feb 8.


A cross-domain charge interaction governs the activity of NO synthase.

Haque MM, Tejero J, Bayachou M, Kenney CT, Stuehr DJ.

J Biol Chem. 2018 Mar 23;293(12):4545-4554. doi: 10.1074/jbc.RA117.000635. Epub 2018 Feb 2.


Radiocarbon chronology of Manot Cave, Israel and Upper Paleolithic dispersals.

Alex B, Barzilai O, Hershkovitz I, Marder O, Berna F, Caracuta V, Abulafia T, Davis L, Goder-Goldberger M, Lavi R, Mintz E, Regev L, Bar-Yosef Mayer D, Tejero JM, Yeshurun R, Ayalon A, Bar-Matthews M, Yasur G, Frumkin A, Latimer B, Hans MG, Boaretto E.

Sci Adv. 2017 Nov 15;3(11):e1701450. doi: 10.1126/sciadv.1701450. eCollection 2017 Nov.


Cytoglobin at the Crossroads of Vascular Remodeling.

Amdahl MB, DeMartino AW, Tejero J, Gladwin MT.

Arterioscler Thromb Vasc Biol. 2017 Oct;37(10):1803-1805. doi: 10.1161/ATVBAHA.117.310058. No abstract available.


Efficient Reduction of Vertebrate Cytoglobins by the Cytochrome b5/Cytochrome b5 Reductase/NADH System.

Amdahl MB, Sparacino-Watkins CE, Corti P, Gladwin MT, Tejero J.

Biochemistry. 2017 Aug 1;56(30):3993-4004. doi: 10.1021/acs.biochem.7b00224. Epub 2017 Jul 19.


Antiretroviral Prescription and Viral Suppression in a Representative Sample of HIV-Infected Persons in Care in 4 Large Metropolitan Areas of the United States, Medical Monitoring Project, 2011-2013.

Wohl AR, Benbow N, Tejero J, Johnson C, Scheer S, Brady K, Gagner A, Hughes A, Eberhart M, Mattson C, Skarbinski J.

J Acquir Immune Defic Syndr. 2017 Oct 1;76(2):158-170. doi: 10.1097/QAI.0000000000001482.


Reply: Carbon Monoxide Exposure in Workplaces, Including Coffee Processing Facilities.

Rose JJ, Wang L, Xu Q, McTiernan CF, Shiva S, Tejero J, Gladwin MT.

Am J Respir Crit Care Med. 2017 Oct 15;196(8):1081-1082. doi: 10.1164/rccm.201704-0773LE. No abstract available.


Hemoglobin inhibits albumin uptake by proximal tubule cells: implications for sickle cell disease.

Eshbach ML, Kaur A, Rbaibi Y, Tejero J, Weisz OA.

Am J Physiol Cell Physiol. 2017 Jun 1;312(6):C733-C740. doi: 10.1152/ajpcell.00021.2017. Epub 2017 Mar 29.


Reply: Better Studies Are Needed to Guide Treatment of Carbon Monoxide Poisoning.

Rose JJ, Wang L, Xu Q, McTiernan CF, Shiva S, Tejero J, Gladwin MT.

Am J Respir Crit Care Med. 2017 Mar 1;195(5):694-695. doi: 10.1164/rccm.201612-2463LE. No abstract available.


Five-coordinate H64Q neuroglobin as a ligand-trap antidote for carbon monoxide poisoning.

Azarov I, Wang L, Rose JJ, Xu Q, Huang XN, Belanger A, Wang Y, Guo L, Liu C, Ucer KB, McTiernan CF, O'Donnell CP, Shiva S, Tejero J, Kim-Shapiro DB, Gladwin MT.

Sci Transl Med. 2016 Dec 7;8(368):368ra173.


Carbon Monoxide Poisoning: Pathogenesis, Management, and Future Directions of Therapy.

Rose JJ, Wang L, Xu Q, McTiernan CF, Shiva S, Tejero J, Gladwin MT.

Am J Respir Crit Care Med. 2017 Mar 1;195(5):596-606. doi: 10.1164/rccm.201606-1275CI. Review. Erratum in: Am J Respir Crit Care Med. 2017 Aug 1;196 (3):398-399.


Globin X is a six-coordinate globin that reduces nitrite to nitric oxide in fish red blood cells.

Corti P, Xue J, Tejero J, Wajih N, Sun M, Stolz DB, Tsang M, Kim-Shapiro DB, Gladwin MT.

Proc Natl Acad Sci U S A. 2016 Jul 26;113(30):8538-43. doi: 10.1073/pnas.1522670113. Epub 2016 Jul 12.


Effects of whole-body vibration after eccentric exercise on muscle soreness and muscle strength recovery.

Timon R, Tejero J, Brazo-Sayavera J, Crespo C, Olcina G.

J Phys Ther Sci. 2016 Jun;28(6):1781-5. doi: 10.1589/jpts.28.1781. Epub 2016 Jun 28.


Peroxidase activation of cytoglobin by anionic phospholipids: Mechanisms and consequences.

Tejero J, Kapralov AA, Baumgartner MP, Sparacino-Watkins CE, Anthonymutu TS, Vlasova II, Camacho CJ, Gladwin MT, Bayir H, Kagan VE.

Biochim Biophys Acta. 2016 May;1861(5):391-401. doi: 10.1016/j.bbalip.2016.02.022. Epub 2016 Feb 27.


Characterization of zebrafish neuroglobin and cytoglobins 1 and 2: Zebrafish cytoglobins provide insights into the transition from six-coordinate to five-coordinate globins.

Corti P, Ieraci M, Tejero J.

Nitric Oxide. 2016 Feb 29;53:22-34. doi: 10.1016/j.niox.2015.12.004. Epub 2015 Dec 22.


Correction to Exploring the Mechanisms of the Reductase Activity of Neuroglobin by Site-Directed Mutagenesis of the Heme Distal Pocket.

Tejero J, Sparacino-Watkins CE, Ragireddy V, Frizzell S, Gladwin MT.

Biochemistry. 2015 Jun 16;54(23):3716. doi: 10.1021/acs.biochem.5b00579. Epub 2015 Jun 8. No abstract available.


Inorganic nitrite improves components of the metabolic syndrome independent of weight change in a murine model of obesity and insulin resistance.

Singamsetty S, Watanabe Y, Guo L, Corey C, Wang Y, Tejero J, McVerry BJ, Gladwin MT, Shiva S, O'Donnell CP.

J Physiol. 2015 Jul 15;593(14):3135-45. doi: 10.1113/JP270386. Epub 2015 Jun 25.


Ebulin from dwarf elder (Sambucus ebulus L.): a mini-review.

Jiménez P, Tejero J, Cordoba-Diaz D, Quinto EJ, Garrosa M, Gayoso MJ, Girbés T.

Toxins (Basel). 2015 Feb 25;7(3):648-58. doi: 10.3390/toxins7030648. Review.


Toxicity of the anti-ribosomal Lectin Ebulin f in lungs and intestines in elderly mice.

Garrosa M, Jiménez P, Tejero J, Cabrero P, Cordoba-Diaz D, Quinto EJ, Gayoso MJ, Girbés T.

Toxins (Basel). 2015 Feb 2;7(2):367-79. doi: 10.3390/toxins7020367.


Elderberries: a source of ribosome-inactivating proteins with lectin activity.

Tejero J, Jiménez P, Quinto EJ, Cordoba-Diaz D, Garrosa M, Cordoba-Diaz M, Gayoso MJ, Girbés T.

Molecules. 2015 Jan 30;20(2):2364-87. doi: 10.3390/molecules20022364. Review.


Exploring the mechanisms of the reductase activity of neuroglobin by site-directed mutagenesis of the heme distal pocket.

Tejero J, Sparacino-Watkins CE, Ragireddy V, Frizzell S, Gladwin MT.

Biochemistry. 2015 Jan 27;54(3):722-33. doi: 10.1021/bi501196k. Epub 2015 Jan 16. Erratum in: Biochemistry. 2015 Jun 16;54(23):3716.


Low variability of growth parameters among six O157:H7 and non-O157:H7 Escherichia coli strains.

Fernández-Escudero I, Caro I, Mateo J, Tejero J, Quinto EJ.

J Food Prot. 2014 Nov;77(11):1988-91. doi: 10.4315/0362-028X.JFP-14-209.


Sulfite Oxidase Catalyzes Single-Electron Transfer at Molybdenum Domain to Reduce Nitrite to Nitric Oxide.

Wang J, Krizowski S, Fischer-Schrader K, Niks D, Tejero J, Sparacino-Watkins C, Wang L, Ragireddy V, Frizzell S, Kelley EE, Zhang Y, Basu P, Hille R, Schwarz G, Gladwin MT.

Antioxid Redox Signal. 2015 Aug 1;23(4):283-94. doi: 10.1089/ars.2013.5397. Epub 2014 Dec 11.


Effects of short-term heating on total polyphenols, anthocyanins, antioxidant activity and lectins of different parts of dwarf elder (Sambucus ebulus L.).

Jimenez P, Cabrero P, Basterrechea JE, Tejero J, Cordoba-Diaz D, Cordoba-Diaz M, Girbes T.

Plant Foods Hum Nutr. 2014 Jun;69(2):168-74. doi: 10.1007/s11130-014-0417-x.


An estimation of mercury concentrations in the local atmosphere of Almadén (Ciudad Real Province, South Central Spain) during the twentieth century.

Tejero J, Higueras PL, Garrido I, Esbrí JM, Oyarzun R, Español S.

Environ Sci Pollut Res Int. 2015 Apr;22(7):4833-41. doi: 10.1007/s11356-014-2860-5. Epub 2014 Apr 16.


Paneth cells are also target of the ribotoxic lectin nigrin b.

Jiménez P, Gayoso MJ, Garrosa M, Córdoba-Díaz D, Cabrero P, Tejero J, Aracil M, Girbés T.

Histol Histopathol. 2014 Aug;29(8):1057-63. doi: 10.14670/HH-29.1057. Epub 2014 Feb 24.


Nitrite reductase and nitric-oxide synthase activity of the mitochondrial molybdopterin enzymes mARC1 and mARC2.

Sparacino-Watkins CE, Tejero J, Sun B, Gauthier MC, Thomas J, Ragireddy V, Merchant BA, Wang J, Azarov I, Basu P, Gladwin MT.

J Biol Chem. 2014 Apr 11;289(15):10345-58. doi: 10.1074/jbc.M114.555177. Epub 2014 Feb 5.


The globin superfamily: functions in nitric oxide formation and decay.

Tejero J, Gladwin MT.

Biol Chem. 2014 Jun;395(6):631-9. doi: 10.1515/hsz-2013-0289. Review.


Isolation and molecular characterization of two lectins from dwarf elder (Sambucus ebulus L.) blossoms related to the Sam n1 allergen.

Jimenez P, Cabrero P, Basterrechea JE, Tejero J, Cordoba-Diaz D, Girbes T.

Toxins (Basel). 2013 Oct 14;5(10):1767-79. doi: 10.3390/toxins5101767.


Thermodynamic characterization of five key kinetic parameters that define neuronal nitric oxide synthase catalysis.

Haque MM, Tejero J, Bayachou M, Wang ZQ, Fadlalla M, Stuehr DJ.

FEBS J. 2013 Sep;280(18):4439-53. doi: 10.1111/febs.12404. Epub 2013 Jul 15.


Direct sGC activation bypasses NO scavenging reactions of intravascular free oxy-hemoglobin and limits vasoconstriction.

Raat NJ, Tabima DM, Specht PA, Tejero J, Champion HC, Kim-Shapiro DB, Baust J, Mik EG, Hildesheim M, Stasch JP, Becker EM, Truebel H, Gladwin MT.

Antioxid Redox Signal. 2013 Dec 20;19(18):2232-43. doi: 10.1089/ars.2013.5181. Epub 2013 Jul 9.


Mechanisms for cellular NO oxidation and nitrite formation in lung epithelial cells.

Zhao XJ, Wang L, Shiva S, Tejero J, Myerburg MM, Wang J, Frizzell S, Gladwin MT.

Free Radic Biol Med. 2013 Aug;61:428-37. doi: 10.1016/j.freeradbiomed.2013.04.031. Epub 2013 Apr 30.


Tetrahydrobiopterin in nitric oxide synthase.

Tejero J, Stuehr D.

IUBMB Life. 2013 Apr;65(4):358-65. doi: 10.1002/iub.1136. Epub 2013 Feb 26. Review.


Toxicity in mice of lectin ebulin f present in dwarf Elderberry (Sambucus ebulus L.).

Jiménez P, Gayoso M, Tejero J, Cabrero P, Córdoba-Díaz D, Basterrechea JE, Girbés T.

Toxicon. 2013 Jan;61:26-9. doi: 10.1016/j.toxicon.2012.10.009. Epub 2012 Nov 8.


Differential sensitivity of D-galactose-binding lectins from fruits of dwarf elder (Sambucus ebulus L.) to a simulated gastric fluid.

Jimenez P, Tejero J, Cabrero P, Cordoba-Diaz D, Girbes T.

Food Chem. 2013 Jan 15;136(2):794-802. doi: 10.1016/j.foodchem.2012.09.011. Epub 2012 Sep 17.


Regional differences among HIV patients in care: California medical monitoring project sites, 2007-2008.

Scheer S, Hughes AJ, Tejero J, Damesyn MA, Mark KE, Arguello TM, Wohl AR.

Open AIDS J. 2012;6:188-95. doi: 10.2174/1874613601206010188. Epub 2012 Sep 7.


Nitrite reductase activity of nonsymbiotic hemoglobins from Arabidopsis thaliana.

Tiso M, Tejero J, Kenney C, Frizzell S, Gladwin MT.

Biochemistry. 2012 Jul 3;51(26):5285-92. Epub 2012 Jun 20.

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