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Items: 41

1.

Comparative pharmacokinetics and pharmacodynamics of intravenous artelinate versus artesunate in uncomplicated Plasmodium coatneyi-infected rhesus monkey model.

Teja-Isavadharm P, Siriyanonda D, Rasameesoraj M, Limsalakpeth A, Chanarat N, Komcharoen N, Weina PJ, Saunders DL, Gettayacamin M, Scott Miller R.

Malar J. 2016 Sep 6;15:453. doi: 10.1186/s12936-016-1456-6.

2.

Ex Vivo Drug Susceptibility Testing and Molecular Profiling of Clinical Plasmodium falciparum Isolates from Cambodia from 2008 to 2013 Suggest Emerging Piperaquine Resistance.

Chaorattanakawee S, Saunders DL, Sea D, Chanarat N, Yingyuen K, Sundrakes S, Saingam P, Buathong N, Sriwichai S, Chann S, Se Y, Yom Y, Heng TK, Kong N, Kuntawunginn W, Tangthongchaiwiriya K, Jacob C, Takala-Harrison S, Plowe C, Lin JT, Chuor CM, Prom S, Tyner SD, Gosi P, Teja-Isavadharm P, Lon C, Lanteri CA.

Antimicrob Agents Chemother. 2015 Aug;59(8):4631-43. doi: 10.1128/AAC.00366-15. Epub 2015 May 26.

3.

Dihydroartemisinin-piperaquine failure associated with a triple mutant including kelch13 C580Y in Cambodia: an observational cohort study.

Spring MD, Lin JT, Manning JE, Vanachayangkul P, Somethy S, Bun R, Se Y, Chann S, Ittiverakul M, Sia-ngam P, Kuntawunginn W, Arsanok M, Buathong N, Chaorattanakawee S, Gosi P, Ta-aksorn W, Chanarat N, Sundrakes S, Kong N, Heng TK, Nou S, Teja-isavadharm P, Pichyangkul S, Phann ST, Balasubramanian S, Juliano JJ, Meshnick SR, Chour CM, Prom S, Lanteri CA, Lon C, Saunders DL.

Lancet Infect Dis. 2015 Jun;15(6):683-91. doi: 10.1016/S1473-3099(15)70049-6. Epub 2015 Apr 12.

PMID:
25877962
4.

Anti-relapse activity of mirincamycin in the Plasmodium cynomolgi sporozoite-infected Rhesus monkey model.

Fracisco S, Teja-isavadharm P, Gettayacamin M, Berman J, Li Q, Melendez V, Saunders D, Xie L, Ohrt C.

Malar J. 2014 Oct 17;13:409. doi: 10.1186/1475-2875-13-409.

5.

Pharmacokinetics and pharmacodynamics of (+)-primaquine and (-)-primaquine enantiomers in rhesus macaques (Macaca mulatta).

Saunders D, Vanachayangkul P, Imerbsin R, Khemawoot P, Siripokasupkul R, Tekwani BL, Sampath A, Nanayakkara NP, Ohrt C, Lanteri C, Gettyacamin M, Teja-Isavadharm P, Walker L.

Antimicrob Agents Chemother. 2014 Dec;58(12):7283-91. doi: 10.1128/AAC.02576-13. Epub 2014 Sep 29.

6.

Randomized, double-blind, placebo-controlled clinical trial of a two-day regimen of dihydroartemisinin-piperaquine for malaria prevention halted for concern over prolonged corrected QT interval.

Manning J, Vanachayangkul P, Lon C, Spring M, So M, Sea D, Se Y, Somethy S, Phann ST, Chann S, Sriwichai S, Buathong N, Kuntawunginn W, Mitprasat M, Siripokasupkul R, Teja-Isavadharm P, Soh E, Timmermans A, Lanteri C, Kaewkungwal J, Auayporn M, Tang D, Chour CM, Prom S, Haigney M, Cantilena L, Saunders D.

Antimicrob Agents Chemother. 2014 Oct;58(10):6056-67. doi: 10.1128/AAC.02667-14. Epub 2014 Aug 4.

7.

Pharmacokinetic evaluation of intravenous artesunate in adults with uncomplicated falciparum malaria in Kenya: a phase II study.

Li Q, Remich S, Miller SR, Ogutu B, Otieno W, Melendez V, Teja-Isavadharm P, Weina PJ, Hickman MR, Smith B, Polhemus M.

Malar J. 2014 Jul 22;13:281. doi: 10.1186/1475-2875-13-281.

8.

Current status of artemisinin-resistant falciparum malaria in South Asia: a randomized controlled artesunate monotherapy trial in Bangladesh.

Starzengruber P, Swoboda P, Fuehrer HP, Khan WA, Hofecker V, Siedl A, Fally M, Graf O, Teja-Isavadharm P, Haque R, Ringwald P, Noedl H.

PLoS One. 2012;7(12):e52236. doi: 10.1371/journal.pone.0052236. Epub 2012 Dec 18.

9.

Population pharmacokinetics of halofantrine in healthy volunteers and patients with symptomatic falciparum malaria.

Klein K, Aarons L, Ter Kuile FO, Nosten F, White NJ, Edstein MD, Teja-Isavadharm P.

J Pharm Pharmacol. 2012 Nov;64(11):1603-13. doi: 10.1111/j.2042-7158.2012.01554.x. Epub 2012 Jul 9.

PMID:
23058047
10.

Optimizing the HRP-2 in vitro malaria drug susceptibility assay using a reference clone to improve comparisons of Plasmodium falciparum field isolates.

Rutvisuttinunt W, Chaorattanakawee S, Tyner SD, Teja-Isavadharm P, Se Y, Yingyuen K, Chaichana P, Bethell D, Walsh DS, Lon C, Fukuda M, Socheat D, Noedl H, Schaecher K, Saunders DL.

Malar J. 2012 Sep 13;11:325. doi: 10.1186/1475-2875-11-325.

11.

Pharmacokinetics and pharmacodynamics of oral artesunate monotherapy in patients with uncomplicated Plasmodium falciparum malaria in western Cambodia.

Saunders D, Khemawoot P, Vanachayangkul P, Siripokasupkul R, Bethell D, Tyner S, Se Y, Rutvisuttinunt W, Sriwichai S, Chanthap L, Lin J, Timmermans A, Socheat D, Ringwald P, Noedl H, Smith B, Fukuda M, Teja-Isavadharm P.

Antimicrob Agents Chemother. 2012 Nov;56(11):5484-93. doi: 10.1128/AAC.00044-12. Epub 2012 Aug 6.

12.

A simplified intravenous artesunate regimen for severe malaria.

Kremsner PG, Taylor T, Issifou S, Kombila M, Chimalizeni Y, Kawaza K, Bouyou Akotet MK, Duscha M, Mordmüller B, Kösters K, Humberg A, Miller RS, Weina P, Duparc S, Möhrle J, Kun JF, Planche T, Teja-Isavadharm P, Simpson JA, Köhler C, Krishna S.

J Infect Dis. 2012 Jan 15;205(2):312-9. doi: 10.1093/infdis/jir724. Epub 2011 Dec 15.

PMID:
22180622
13.

Absolute bioavailability of cis-mirincamycin and trans-mirincamycin in healthy rhesus monkeys and ex vivo antimalarial activity against Plasmodium falciparum.

Khemawoot P, Saunders D, Rasameesoraj M, Melendez V, Imerbsin R, Ohrt C, Fracisco S, Teja-Isavadharm P.

Antimicrob Agents Chemother. 2011 Dec;55(12):5881-6. doi: 10.1128/AAC.01619-10. Epub 2011 Sep 26.

14.

Artesunate dose escalation for the treatment of uncomplicated malaria in a region of reported artemisinin resistance: a randomized clinical trial.

Bethell D, Se Y, Lon C, Tyner S, Saunders D, Sriwichai S, Darapiseth S, Teja-Isavadharm P, Khemawoot P, Schaecher K, Ruttvisutinunt W, Lin J, Kuntawungin W, Gosi P, Timmermans A, Smith B, Socheat D, Fukuda MM.

PLoS One. 2011;6(5):e19283. doi: 10.1371/journal.pone.0019283. Epub 2011 May 13.

15.

A simplified liquid chromatography-mass spectrometry assay for artesunate and dihydroartemisinin, its metabolite, in human plasma.

Teja-Isavadharm P, Siriyanonda D, Siripokasupkul R, Apinan R, Chanarat N, Lim A, Wannaying S, Saunders D, Fukuda MM, Miller RS, Weina PJ, Meléndez V.

Molecules. 2010 Dec 1;15(12):8747-68. doi: 10.3390/molecules15128747.

16.

Dose-dependent risk of neutropenia after 7-day courses of artesunate monotherapy in Cambodian patients with acute Plasmodium falciparum malaria.

Bethell D, Se Y, Lon C, Socheat D, Saunders D, Teja-Isavadharm P, Khemawoot P, Darapiseth S, Lin J, Sriwichai S, Kuntawungin W, Surasri S, Lee SJ, Sarim S, Tyner S, Smith B, Fukuda MM.

Clin Infect Dis. 2010 Dec 15;51(12):e105-14. doi: 10.1086/657402. Epub 2010 Nov 11.

PMID:
21070142
17.

Artemisinin resistance in Cambodia: a clinical trial designed to address an emerging problem in Southeast Asia.

Noedl H, Se Y, Sriwichai S, Schaecher K, Teja-Isavadharm P, Smith B, Rutvisuttinunt W, Bethell D, Surasri S, Fukuda MM, Socheat D, Chan Thap L.

Clin Infect Dis. 2010 Dec 1;51(11):e82-9. doi: 10.1086/657120. Epub 2010 Oct 28.

PMID:
21028985
18.

Nonisotopic, semiautomated plasmodium falciparum bioassay for measurement of antimalarial drug levels in serum or plasma.

Noedl H, Teja-Isavadharm P, Miller RS.

Antimicrob Agents Chemother. 2004 Nov;48(11):4485-7.

19.

Plasmodium falciparum-based bioassay for measurement of artemisinin derivatives in plasma or serum.

Teja-Isavadharm P, Peggins JO, Brewer TG, White NJ, Webster HK, Kyle DE.

Antimicrob Agents Chemother. 2004 Mar;48(3):954-60.

20.

Artemether bioavailability after oral or intramuscular administration in uncomplicated falciparum malaria.

Silamut K, Newton PN, Teja-Isavadharm P, Suputtamongkol Y, Siriyanonda D, Rasameesoraj M, Pukrittayakamee S, White NJ.

Antimicrob Agents Chemother. 2003 Dec;47(12):3795-8.

21.

Comparison of oral artesunate and dihydroartemisinin antimalarial bioavailabilities in acute falciparum malaria.

Newton PN, van Vugt M, Teja-Isavadharm P, Siriyanonda D, Rasameesoroj M, Teerapong P, Ruangveerayuth R, Slight T, Nosten F, Suputtamongkol Y, Looareesuwan S, White NJ.

Antimicrob Agents Chemother. 2002 Apr;46(4):1125-7.

22.

Comparative pharmacokinetics and effect kinetics of orally administered artesunate in healthy volunteers and patients with uncomplicated falciparum malaria.

Teja-Isavadharm P, Watt G, Eamsila C, Jongsakul K, Li Q, Keeratithakul G, Sirisopana N, Luesutthiviboon L, Brewer TG, Kyle DE.

Am J Trop Med Hyg. 2001 Dec;65(6):717-21.

PMID:
11791963
23.

A comparison of oral artesunate and artemether antimalarial bioactivities in acute falciparum malaria.

Suputtamongkol Y, Newton PN, Angus B, Teja-Isavadharm P, Keeratithakul D, Rasameesoraj M, Pukrittayakamee S, White NJ.

Br J Clin Pharmacol. 2001 Dec;52(6):655-61.

24.

Antimalarial bioavailability and disposition of artesunate in acute falciparum malaria.

Newton P, Suputtamongkol Y, Teja-Isavadharm P, Pukrittayakamee S, Navaratnam V, Bates I, White N.

Antimicrob Agents Chemother. 2000 Apr;44(4):972-7.

25.

Pharmacokinetics of quinine and 3-hydroxyquinine in severe falciparum malaria with acute renal failure.

Newton P, Keeratithakul D, Teja-Isavadharm P, Pukrittayakamee S, Kyle D, White N.

Trans R Soc Trop Med Hyg. 1999 Jan-Feb;93(1):69-72.

PMID:
10492795
26.

Pharmacokinetics and pharmacodynamics of qinghaosu derivatives: how do they impact on the choice of drug and the dosage regimens?

Kyle DE, Teja-Isavadharm P, Li Q, Leo K.

Med Trop (Mars). 1998;58(3 Suppl):38-44. Review.

PMID:
10212896
27.

Pustular eruption in a malaria patient treated with chloroquine.

Wilairatana P, Looareesuwan S, Riganti M, Teja-Isavadharm P, Keeratithakul D, Eickmeyer S, Walsh DS.

Int J Dermatol. 1998 Sep;37(9):713-4. No abstract available.

PMID:
9762829
28.

Lack of a significant adverse cardiovascular effect of combined quinine and mefloquine therapy for uncomplicated malaria.

Supanaranond W, Suputtamongkol Y, Davis TM, Pukrittayakamee S, Teja-Isavadharm P, Webster HK, White NJ.

Trans R Soc Trop Med Hyg. 1997 Nov-Dec;91(6):694-6.

PMID:
9509182
29.

Comparative clinical trial of artesunate suppositories and oral artesunate in combination with mefloquine in the treatment of children with acute falciparum malaria.

Sabchareon A, Attanath P, Chanthavanich P, Phanuaksook P, Prarinyanupharb V, Poonpanich Y, Mookmanee D, Teja-Isavadharm P, Heppner DG, Brewer TG, Chongsuphajaisiddhi T.

Am J Trop Med Hyg. 1998 Jan;58(1):11-6.

PMID:
9452284
30.

Pustular eruption in a malaria patient treated with chloroquine.

Wilairatana P, Looareesuwan S, Riganti M, Teja-Isavadharm P, Keeratithakul D, Eickmeyer S, Walsh DS.

Int J Dermatol. 1997 Aug;36(8):634-5. No abstract available.

PMID:
9329900
31.

Pharmacokinetics of oral artesunate in children with moderately severe Plasmodium falciparum malaria.

Bethell DB, Teja-Isavadharm P, Cao XT, Pham TT, Ta TT, Tran TN, Nguyen TT, Pham TP, Kyle D, Day NP, White NJ.

Trans R Soc Trop Med Hyg. 1997 Mar-Apr;91(2):195-8.

PMID:
9196768
32.

A study of the factors affecting the metabolic clearance of quinine in malaria.

Pukrittayakamee S, Looareesuwan S, Keeratithakul D, Davis TM, Teja-Isavadharm P, Nagachinta B, Weber A, Smith AL, Kyle D, White NJ.

Eur J Clin Pharmacol. 1997;52(6):487-93.

PMID:
9342585
33.

Comparative bioavailability of oral, rectal, and intramuscular artemether in healthy subjects: use of simultaneous measurement by high performance liquid chromatography and bioassay.

Teja-Isavadharm P, Nosten F, Kyle DE, Luxemburger C, Ter Kuile F, Peggins JO, Brewer TG, White NJ.

Br J Clin Pharmacol. 1996 Nov;42(5):599-604.

34.

Scrub typhus infections poorly responsive to antibiotics in northern Thailand.

Watt G, Chouriyagune C, Ruangweerayud R, Watcharapichat P, Phulsuksombati D, Jongsakul K, Teja-Isavadharm P, Bhodhidatta D, Corcoran KD, Dasch GA, Strickman D.

Lancet. 1996 Jul 13;348(9020):86-9.

PMID:
8676722
35.

Pharmacokinetics of an extended-dose halofantrine regimen in patients with malaria and in healthy volunteers.

Ohrt C, Watt G, Teja-Isavadharm P, Keeratithakul D, Loesuttiviboon L, Webster HK, Schuster B, Fleckenstein L.

Clin Pharmacol Ther. 1995 May;57(5):525-32.

PMID:
7768075
36.

Oxidative activation of proguanil and dapsone acetylation in Thai soldiers.

Edstein MD, Shanks GD, Teja-Isavadharm P, Rieckmann KH, Webster HK.

Br J Clin Pharmacol. 1994 Jan;37(1):67-70.

37.

Pharmacokinetics, efficacy and toxicity of parenteral halofantrine in uncomplicated malaria.

Krishna S, ter Kuile F, Supanaranond W, Pukrittayakamee S, Teja-Isavadharm P, Kyle D, White NJ.

Br J Clin Pharmacol. 1993 Dec;36(6):585-91.

38.

Macrophage activation in vivax malaria: fever is associated with increased levels of neopterin and interferon-gamma.

Brown AE, Teja-Isavadharm P, Webster HK.

Parasite Immunol. 1991 Nov;13(6):673-9.

PMID:
1811217
39.

Measurement of ciprofloxacin in human plasma, whole blood, and erythrocytes by high-performance liquid chromatography.

Teja-Isavadharm P, Keeratithakul D, Watt G, Webster HK, Edstein MD.

Ther Drug Monit. 1991 May;13(3):263-7.

PMID:
1926283
40.

An improved high-performance liquid chromatographic method for the simultaneous measurement of halofantrine and desbutylhalofantrine in human serum.

Keeratithakul D, Teja-Isavadharm P, Shanks GD, Webster HK, Edstein MD.

Ther Drug Monit. 1991 Jan;13(1):64-8.

PMID:
2057994
41.

Macrophage activation in falciparum malaria as measured by neopterin and interferon-gamma.

Brown AE, Webster HK, Teja-Isavadharm P, Keeratithakul D.

Clin Exp Immunol. 1990 Oct;82(1):97-101.

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