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Items: 1 to 50 of 72

1.

Native serotonin 5-HT2C receptors are expressed as homodimers on the apical surface of choroid plexus epithelial cells.

Herrick-Davis K, Grinde E, Lindsley T, Teitler M, Mancia F, Cowan A, Mazurkiewicz JE.

Mol Pharmacol. 2015 Apr;87(4):660-73. doi: 10.1124/mol.114.096636. Epub 2015 Jan 21.

2.
3.

Distribution of 5-ht(1E) receptors in the mammalian brain and cerebral vasculature: an immunohistochemical and pharmacological study.

Klein MT, Teitler M.

Br J Pharmacol. 2012 Jun;166(4):1290-302. doi: 10.1111/j.1476-5381.2012.01868.x.

4.

A new approach for studying GPCR dimers: drug-induced inactivation and reactivation to reveal GPCR dimer function in vitro, in primary culture, and in vivo.

Teitler M, Klein MT.

Pharmacol Ther. 2012 Feb;133(2):205-17. doi: 10.1016/j.pharmthera.2011.10.007. Epub 2011 Nov 17. Review.

5.

Toward selective drug development for the human 5-hydroxytryptamine 1E receptor: a comparison of 5-hydroxytryptamine 1E and 1F receptor structure-affinity relationships.

Klein MT, Dukat M, Glennon RA, Teitler M.

J Pharmacol Exp Ther. 2011 Jun;337(3):860-7. doi: 10.1124/jpet.111.179606. Epub 2011 Mar 21.

6.
7.
8.

Clozapine and other competitive antagonists reactivate risperidone-inactivated h5-HT7 receptors: radioligand binding and functional evidence for GPCR homodimer protomer interactions.

Teitler M, Toohey N, Knight JA, Klein MT, Smith C.

Psychopharmacology (Berl). 2010 Dec;212(4):687-97. doi: 10.1007/s00213-010-2001-x. Epub 2010 Sep 9.

9.

Human 5-HT7 receptor-induced inactivation of forskolin-stimulated adenylate cyclase by risperidone, 9-OH-risperidone and other "inactivating antagonists".

Toohey N, Klein MT, Knight J, Smith C, Teitler M.

Mol Pharmacol. 2009 Sep;76(3):552-9. doi: 10.1124/mol.109.056283. Epub 2009 Jun 9.

10.

Guinea pig hippocampal 5-HT(1E) receptors: a tool for selective drug development.

Klein MT, Teitler M.

J Neurochem. 2009 Apr;109(1):268-74. doi: 10.1111/j.1471-4159.2009.05958.x. Epub 2009 Feb 5.

11.

Pharmacological analysis of the novel, rapid, and potent inactivation of the human 5-Hydroxytryptamine7 receptor by risperidone, 9-OH-Risperidone, and other inactivating antagonists.

Knight JA, Smith C, Toohey N, Klein MT, Teitler M.

Mol Pharmacol. 2009 Feb;75(2):374-80. doi: 10.1124/mol.108.052084. Epub 2008 Nov 7.

12.

Risperidone irreversibly binds to and inactivates the h5-HT7 serotonin receptor.

Smith C, Rahman T, Toohey N, Mazurkiewicz J, Herrick-Davis K, Teitler M.

Mol Pharmacol. 2006 Oct;70(4):1264-70. Epub 2006 Jul 26.

PMID:
16870886
13.

Stable expression of constitutively activated mutant h5HT6 and h5HT7 serotonin receptors: inverse agonist activity of antipsychotic drugs.

Purohit A, Smith C, Herrick-Davis K, Teitler M.

Psychopharmacology (Berl). 2005 May;179(2):461-9. Epub 2004 Dec 10.

PMID:
15821958
14.

Binding of tryptamine analogs at h5-HT1E receptors: a structure-affinity investigation.

Dukat M, Smith C, Herrick-Davis K, Teitler M, Glennon RA.

Bioorg Med Chem. 2004 May 15;12(10):2545-52.

PMID:
15110837
15.

Binding of beta-carbolines at 5-HT(2) serotonin receptors.

Grella B, Teitler M, Smith C, Herrick-Davis K, Glennon RA.

Bioorg Med Chem Lett. 2003 Dec 15;13(24):4421-5.

PMID:
14643338
16.

Arylguanidine and arylbiguanide binding at 5-HT3 serotonin receptors: a QSAR study.

Glennon RA, Daoud MK, Dukat M, Teitler M, Herrick-Davis K, Purohit A, Syed H.

Bioorg Med Chem. 2003 Oct 1;11(20):4449-54.

PMID:
13129581
17.

Behavioral characterization of 2-O-desmethyl and 5-O-desmethyl metabolites of the phenylethylamine hallucinogen DOM.

Eckler JR, Chang-Fong J, Rabin RA, Smith C, Teitler M, Glennon RA, Winter JC.

Pharmacol Biochem Behav. 2003 Jul;75(4):845-52.

PMID:
12957227
18.

Binding of tetrahydrocarboline derivatives at human 5-HT5A receptors.

Khorana N, Smith C, Herrick-Davis K, Purohit A, Teitler M, Grella B, Dukat M, Glennon RA.

J Med Chem. 2003 Aug 28;46(18):3930-7.

PMID:
12930153
19.

Conformationally-restricted analogues and partition coefficients of the 5-HT3 serotonin receptor ligands meta-chlorophenylbiguanide (mCPBG) and meta-chlorophenylguanidine (mCPG).

Rahman AA, Daoud MK, Dukat M, Herrick-Davis K, Purohit A, Teitler M, do Amaral AT, Malvezzi A, Glennon RA.

Bioorg Med Chem Lett. 2003 Mar 24;13(6):1119-23. Erratum in: Bioorg Med Chem Lett. 2012 Oct 15;22(20):6526.

PMID:
12643925
20.

gamma-Carbolines: binding at 5-HT5A serotonin receptors.

Khorana N, Purohit A, Herrick-Davis K, Teitler M, Glennon RA.

Bioorg Med Chem. 2003 Mar 6;11(5):717-22.

PMID:
12538001
21.
22.

Ketanserin and spiperone as templates for novel serotonin 5-HT(2A) antagonists.

Glennon RA, Metwally K, Dukat M, Ismaiel AM, De los Angeles J, Herndon J, Teitler M, Khorana N.

Curr Top Med Chem. 2002 Jun;2(6):539-58. Review.

PMID:
12052193
23.

Constitutive activity of G-protein coupled receptors: emphasis on serotonin receptors.

Teitler M, Herrick-Davis K, Purohit A.

Curr Top Med Chem. 2002 Jun;2(6):529-38. Review.

PMID:
12052192
24.

Evaluation of isotryptamine derivatives at 5-HT(2) serotonin receptors.

Chang-Fong J, Addo J, Dukat M, Smith C, Mitchell NA, Herrick-Davis K, Teitler M, Glennon RA.

Bioorg Med Chem Lett. 2002 Jan 21;12(2):155-8.

PMID:
11755343
25.

1-[2-methoxy-5-(3-phenylpropyl)]-2-aminopropane unexpectedly shows 5-HT(2A) serotonin receptor affinity and antagonist character.

Rangisetty JB, Dukat M, Dowd CS, Herrick-Davis K, DuPre A, Gadepalli S, Teitler M, Kelley CR, Sharif NA, Glennon RA.

J Med Chem. 2001 Sep 27;44(20):3283-91.

PMID:
11563927
26.

The binding of arylguanidines at 5-HT(3) serotonin receptors: a structure-affinity investigation.

Dukat M, Choi YN, Teitler M, Du Pre A, Herrick-Davis K, Smith C, Glennon RA.

Bioorg Med Chem Lett. 2001 Jun 18;11(12):1599-603.

PMID:
11412989
27.

Inverse agonist activity of atypical antipsychotic drugs at human 5-hydroxytryptamine2C receptors.

Herrick-Davis K, Grinde E, Teitler M.

J Pharmacol Exp Ther. 2000 Oct;295(1):226-32.

PMID:
10991983
28.

Behavioural sensitization to cocaine is dissociated from changes in striatal NMDA receptor levels.

Szumlinski KK, Herrick-Davis K, Teitler M, Maisonneuve IM, Glick SD.

Neuroreport. 2000 Aug 21;11(12):2785-8.

PMID:
10976963
29.

1-[4-(3-Phenylalkyl)phenyl]-2-aminopropanes as 5-HT(2A) partial agonists.

Dowd CS, Herrick-Davis K, Egan C, DuPre A, Smith C, Teitler M, Glennon RA.

J Med Chem. 2000 Aug 10;43(16):3074-84.

PMID:
10956215
30.

Binding of beta-carbolines and related agents at serotonin (5-HT(2) and 5-HT(1A)), dopamine (D(2)) and benzodiazepine receptors.

Glennon RA, Dukat M, Grella B, Hong S, Costantino L, Teitler M, Smith C, Egan C, Davis K, Mattson MV.

Drug Alcohol Depend. 2000 Aug 1;60(2):121-32.

PMID:
10940539
31.

Agonist high and low affinity state ratios predict drug intrinsic activity and a revised ternary complex mechanism at serotonin 5-HT(2A) and 5-HT(2C) receptors.

Egan C, Grinde E, Dupre A, Roth BL, Hake M, Teitler M, Herrick-Davis K.

Synapse. 2000 Feb;35(2):144-50.

PMID:
10611640
32.

Beta-blocker selectivity at cloned human beta 1- and beta 2-adrenergic receptors.

Smith C, Teitler M.

Cardiovasc Drugs Ther. 1999 Apr;13(2):123-6.

PMID:
10372227
33.

Pharmacological characterization of the constitutively activated state of the serotonin 5-HT2C receptor.

Herrick-Davis K, Grinde E, Gauthier C, Teitler M.

Ann N Y Acad Sci. 1998 Dec 15;861:140-5.

PMID:
9928251
34.
35.

Spiperone: influence of spiro ring substituents on 5-HT2A serotonin receptor binding.

Metwally KA, Dukat M, Egan CT, Smith C, DuPre A, Gauthier CB, Herrick-Davis K, Teitler M, Glennon RA.

J Med Chem. 1998 Dec 3;41(25):5084-93.

PMID:
9836624
37.

Investigation of hallucinogenic and related beta-carbolines.

Grella B, Dukat M, Young R, Teitler M, Herrick-Davis K, Gauthier CB, Glennon RA.

Drug Alcohol Depend. 1998 Apr 1;50(2):99-107.

PMID:
9649961
38.

Benzylimidazolines as h5-HT1B/1D serotonin receptor ligands: a structure-affinity investigation.

Law H, Dukat M, Teitler M, Lee DK, Mazzocco L, Kamboj R, Rampersad V, Prisinzano T, Glennon RA.

J Med Chem. 1998 Jun 18;41(13):2243-51.

PMID:
9632357
39.

Agonist activity of LSD and lisuride at cloned 5HT2A and 5HT2C receptors.

Egan CT, Herrick-Davis K, Miller K, Glennon RA, Teitler M.

Psychopharmacology (Berl). 1998 Apr;136(4):409-14.

PMID:
9600588
40.

2-(1-Naphthyloxy)ethylamines with enhanced affinity for human 5-HT1D beta (h5-HT1B) serotonin receptors.

Ismaiel AM, Dukat M, Law H, Kamboj R, Fan E, Lee DK, Mazzocco L, Buekschkens D, Teitler M, Pierson ME, Glennon RA.

J Med Chem. 1997 Dec 19;40(26):4415-9.

PMID:
9435911
41.

Activating mutations of the serotonin 5-HT2C receptor.

Herrick-Davis K, Egan C, Teitler M.

J Neurochem. 1997 Sep;69(3):1138-44.

42.

Structure-activity relationships for the binding of arylpiperazines and arylbiguanides at 5-HT3 serotonin receptors.

Dukat M, Abdel-Rahman AA, Ismaiel AM, Ingher S, Teitler M, Gyermek L, Glennon RA.

J Med Chem. 1996 Sep 27;39(20):4017-26.

PMID:
8831767
43.

Binding of O-alkyl derivatives of serotonin at human 5-HT1D beta receptors.

Glennon RA, Hong SS, Bondarev M, Law H, Dukat M, Rakhi S, Power P, Fan E, Kinneau D, Kamboj R, Teitler M, Herrick-Davis K, Smith C.

J Med Chem. 1996 Jan 5;39(1):314-22.

PMID:
8568822
44.

Ketanserin analogues: the effect of structural modification on 5-HT2 serotonin receptor binding.

Ismaiel AM, Arruda K, Teitler M, Glennon RA.

J Med Chem. 1995 Mar 31;38(7):1196-202.

PMID:
7707322
45.

Radioligand-binding study of noribogaine, a likely metabolite of ibogaine.

Pearl SM, Herrick-Davis K, Teitler M, Glick SD.

Brain Res. 1995 Mar 27;675(1-2):342-4.

PMID:
7796150
46.

The development of beta 1-adrenoceptors in brown adipose tissue following prenatal alcohol exposure.

Zimmerberg B, Smith CD, Weider JM, Teitler M.

Alcohol. 1995 Jan-Feb;12(1):71-7.

PMID:
7748518
47.

5-(Nonyloxy)tryptamine: a novel high-affinity 5-HT1D beta serotonin receptor agonist.

Glennon RA, Hong SS, Dukat M, Teitler M, Davis K.

J Med Chem. 1994 Sep 2;37(18):2828-30. No abstract available.

PMID:
8071931
48.

Influence of amine substituents on 5-HT2A versus 5-HT2C binding of phenylalkyl- and indolylalkylamines.

Glennon RA, Dukat M, el-Bermawy M, Law H, De los Angeles J, Teitler M, King A, Herrick-Davis K.

J Med Chem. 1994 Jun 24;37(13):1929-35.

PMID:
8027974
50.

Multiple serotonin receptor subtypes: molecular cloning and functional expression.

Teitler M, Herrick-Davis K.

Crit Rev Neurobiol. 1994;8(3):175-88. Review.

PMID:
7923395

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