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Items: 12

1.

Influence of Stereochemistry on the Bioactivation and Glucuronidation of 4-Ipomeanol.

Teitelbaum AM, McDonald MG, Kowalski JP, Parkinson OT, Scian M, Whittington D, Roellecke K, Hanenberg H, Wiek C, Rettie AE.

J Pharmacol Exp Ther. 2018 Nov 8. pii: jpet.118.249771. doi: 10.1124/jpet.118.249771. [Epub ahead of print]

2.

N-Methylation of BI 187004 by Thiol S-Methyltransferase.

Maw HH, Zeng X, Campbell S, Taub ME, Teitelbaum AM.

Drug Metab Dispos. 2018 Jun;46(6):770-778. doi: 10.1124/dmd.117.079764. Epub 2018 Mar 7.

PMID:
29514826
3.

Nicotine dependence is associated with functional variation in FMO3, an enzyme that metabolizes nicotine in the brain.

Teitelbaum AM, Murphy SE, Akk G, Baker TB, Germann A, von Weymarn LB, Bierut LJ, Goate A, Kharasch ED, Bloom AJ.

Pharmacogenomics J. 2018 Jan;18(1):136-143. doi: 10.1038/tpj.2016.92. Epub 2017 Mar 14.

4.

Misidentification of Bupropion Glucuronide Metabolites and Re-evaluation of Metabolite Pharmacokinetics.

Teitelbaum AM, Kharasch ED.

Drug Metab Dispos. 2016 Nov;44(11):1851. No abstract available.

5.

Species Differences in Microsomal Oxidation and Glucuronidation of 4-Ipomeanol: Relationship to Target Organ Toxicity.

Parkinson OT, Teitelbaum AM, Whittington D, Kelly EJ, Rettie AE.

Drug Metab Dispos. 2016 Oct;44(10):1598-602. doi: 10.1124/dmd.116.070003. Epub 2016 Jul 28.

6.

Development, validation and application of a comprehensive stereoselective LC/MS-MS assay for bupropion and oxidative, reductive, and glucuronide metabolites in human urine.

Teitelbaum AM, Flaker AM, Kharasch ED.

J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Aug 1;1027:239-53. doi: 10.1016/j.jchromb.2016.05.036. Epub 2016 May 24.

7.

Efficient Syntheses of Vitamin K Chain-Shortened Acid Metabolites.

Teitelbaum AM, Scian M, Nelson WL, Rettie AE.

Synthesis (Stuttg). 2015 Apr;47(7):944-948.

8.

Development and validation of a high-throughput stereoselective LC-MS/MS assay for bupropion, hydroxybupropion, erythrohydrobupropion, and threohydrobupropion in human plasma.

Teitelbaum AM, Flaker AM, Kharasch ED.

J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Apr 1;1017-1018:101-113. doi: 10.1016/j.jchromb.2016.02.032. Epub 2016 Feb 27.

9.

Synthesis, pH-dependent, and plasma stability of meropenem prodrugs for potential use against drug-resistant tuberculosis.

Teitelbaum AM, Meissner A, Harding RA, Wong CA, Aldrich CC, Remmel RP.

Bioorg Med Chem. 2013 Sep 1;21(17):5605-17. doi: 10.1016/j.bmc.2013.05.024. Epub 2013 May 24.

10.

Characterization of AusA: a dimodular nonribosomal peptide synthetase responsible for the production of aureusimine pyrazinones.

Wilson DJ, Shi C, Teitelbaum AM, Gulick AM, Aldrich CC.

Biochemistry. 2013 Feb 5;52(5):926-37. doi: 10.1021/bi301330q. Epub 2013 Jan 23.

11.

9-Amino acridine pharmacokinetics, brain distribution, and in vitro/in vivo efficacy against malignant glioma.

Teitelbaum AM, Gallardo JL, Bedi J, Giri R, Benoit AR, Olin MR, Morizio KM, Ohlfest JR, Remmel RP, Ferguson DM.

Cancer Chemother Pharmacol. 2012 Jun;69(6):1519-27. doi: 10.1007/s00280-012-1855-5. Epub 2012 Mar 9.

PMID:
22402637
12.

Inhibitors of the salicylate synthase (MbtI) from Mycobacterium tuberculosis discovered by high-throughput screening.

Vasan M, Neres J, Williams J, Wilson DJ, Teitelbaum AM, Remmel RP, Aldrich CC.

ChemMedChem. 2010 Dec 3;5(12):2079-87. doi: 10.1002/cmdc.201000275.

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