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Items: 1 to 50 of 177

1.

Shared CaM- and S100A1-binding epitopes in the distal TRPM4 N terminus.

Bousova K, Herman P, Vecer J, Bednarova L, Monincova L, Majer P, Vyklicky L, Vondrasek J, Teisinger J.

FEBS J. 2018 Feb;285(3):599-613. doi: 10.1111/febs.14362. Epub 2017 Dec 29.

2.

The characterization of a novel S100A1 binding site in the N-terminus of TRPM1.

Jirku M, Lansky Z, Bednarova L, Sulc M, Monincova L, Majer P, Vyklicky L, Vondrasek J, Teisinger J, Bousova K.

Int J Biochem Cell Biol. 2016 Sep;78:186-193. doi: 10.1016/j.biocel.2016.07.014. Epub 2016 Jul 17.

PMID:
27435061
3.

Characterization of the part of N-terminal PIP2 binding site of the TRPM1 channel.

Jirku M, Bumba L, Bednarova L, Kubala M, Sulc M, Franek M, Vyklicky L, Vondrasek J, Teisinger J, Bousova K.

Biophys Chem. 2015 Dec;207:135-42. doi: 10.1016/j.bpc.2015.10.005. Epub 2015 Oct 27.

PMID:
26544986
4.

PIP2 and PIP3 interact with N-terminus region of TRPM4 channel.

Bousova K, Jirku M, Bumba L, Bednarova L, Sulc M, Franek M, Vyklicky L, Vondrasek J, Teisinger J.

Biophys Chem. 2015 Oct;205:24-32. doi: 10.1016/j.bpc.2015.06.004. Epub 2015 Jun 9.

PMID:
26071843
5.

Ca(2+) binding protein S100A1 competes with calmodulin and PIP2 for binding site on the C-terminus of the TPRV1 receptor.

Grycova L, Holendova B, Lansky Z, Bumba L, Jirku M, Bousova K, Teisinger J.

ACS Chem Neurosci. 2015 Mar 18;6(3):386-92. doi: 10.1021/cn500250r. Epub 2014 Dec 31.

PMID:
25543978
6.

Characterization of the S100A1 protein binding site on TRPC6 C-terminus.

Bily J, Grycova L, Holendova B, Jirku M, Janouskova H, Bousova K, Teisinger J.

PLoS One. 2013 May 3;8(5):e62677. doi: 10.1371/journal.pone.0062677. Print 2013.

7.

Activation of p53 pathway by Nutlin-3a inhibits the expression of the therapeutic target α5 integrin in colon cancer cells.

Janouskova H, Ray AM, Noulet F, Lelong-Rebel I, Choulier L, Schaffner F, Lehmann M, Martin S, Teisinger J, Dontenwill M.

Cancer Lett. 2013 Aug 19;336(2):307-18. doi: 10.1016/j.canlet.2013.03.018. Epub 2013 Mar 21.

PMID:
23523610
8.

Protons stabilize the closed conformation of gain-of-function mutants of the TRPV1 channel.

Boukalova S, Teisinger J, Vlachova V.

Biochim Biophys Acta. 2013 Mar;1833(3):520-8. doi: 10.1016/j.bbamcr.2012.11.017. Epub 2012 Dec 4.

9.

Integrative binding sites within intracellular termini of TRPV1 receptor.

Grycova L, Holendova B, Bumba L, Bily J, Jirku M, Lansky Z, Teisinger J.

PLoS One. 2012;7(10):e48437. doi: 10.1371/journal.pone.0048437. Epub 2012 Oct 31.

10.

PtdIns(4,5)P2 interacts with CaM binding domains on TRPM3 N-terminus.

Holendova B, Grycova L, Jirku M, Teisinger J.

Channels (Austin). 2012 Nov-Dec;6(6):479-82. doi: 10.4161/chan.22177. Epub 2012 Sep 18.

11.

Integrin α5β1 plays a critical role in resistance to temozolomide by interfering with the p53 pathway in high-grade glioma.

Janouskova H, Maglott A, Leger DY, Bossert C, Noulet F, Guerin E, Guenot D, Pinel S, Chastagner P, Plenat F, Entz-Werle N, Lehmann-Che J, Godet J, Martin S, Teisinger J, Dontenwill M.

Cancer Res. 2012 Jul 15;72(14):3463-70. doi: 10.1158/0008-5472.CAN-11-4199. Epub 2012 May 16.

12.

Calmodulin and S100A1 protein interact with N terminus of TRPM3 channel.

Holakovska B, Grycova L, Jirku M, Sulc M, Bumba L, Teisinger J.

J Biol Chem. 2012 May 11;287(20):16645-55. doi: 10.1074/jbc.M112.350686. Epub 2012 Mar 27.

13.

Conserved residues within the putative S4-S5 region serve distinct functions among thermosensitive vanilloid transient receptor potential (TRPV) channels.

Boukalova S, Marsakova L, Teisinger J, Vlachova V.

J Biol Chem. 2010 Dec 31;285(53):41455-62. doi: 10.1074/jbc.M110.145466. Epub 2010 Nov 2.

14.

The C-terminal basic residues contribute to the chemical- and voltage-dependent activation of TRPA1.

Samad A, Sura L, Benedikt J, Ettrich R, Minofar B, Teisinger J, Vlachova V.

Biochem J. 2011 Jan 1;433(1):197-204. doi: 10.1042/BJ20101256.

15.

A "cute" desensitization of TRPV1.

Touska F, Marsakova L, Teisinger J, Vlachova V.

Curr Pharm Biotechnol. 2011 Jan 1;12(1):122-9. Review.

PMID:
20932251
16.

Characterization of calmodulin binding domains in TRPV2 and TRPV5 C-tails.

Holakovska B, Grycova L, Bily J, Teisinger J.

Amino Acids. 2011 Feb;40(2):741-8. doi: 10.1007/s00726-010-0712-2. Epub 2010 Aug 5.

PMID:
20686800
17.

The interactions of the C-terminal region of the TRPC6 channel with calmodulin.

Friedlova E, Grycova L, Holakovska B, Silhan J, Janouskova H, Sulc M, Obsilova V, Obsil T, Teisinger J.

Neurochem Int. 2010 Jan;56(2):363-6. doi: 10.1016/j.neuint.2009.11.009. Epub 2009 Nov 20.

PMID:
19932145
18.

Changes in electrostatic surface potential of Na+/K+-ATPase cytoplasmic headpiece induced by cytoplasmic ligand(s) binding.

Kubala M, Grycova L, Lansky Z, Sklenovsky P, Janovska M, Otyepka M, Teisinger J.

Biophys J. 2009 Sep 16;97(6):1756-64. doi: 10.1016/j.bpj.2009.07.002.

19.

Essential role for the putative S6 inner pore region in the activation gating of the human TRPA1 channel.

Benedikt J, Samad A, Ettrich R, Teisinger J, Vlachova V.

Biochim Biophys Acta. 2009 Jul;1793(7):1279-88. doi: 10.1016/j.bbamcr.2009.04.014. Epub 2009 May 5.

20.

14-3-3 protein masks the DNA binding interface of forkhead transcription factor FOXO4.

Silhan J, Vacha P, Strnadova P, Vecer J, Herman P, Sulc M, Teisinger J, Obsilova V, Obsil T.

J Biol Chem. 2009 Jul 17;284(29):19349-60. doi: 10.1074/jbc.M109.002725. Epub 2009 May 5.

21.

ATP and magnesium drive conformational changes of the Na+/K+-ATPase cytoplasmic headpiece.

Grycova L, Sklenovsky P, Lansky Z, Janovska M, Otyepka M, Amler E, Teisinger J, Kubala M.

Biochim Biophys Acta. 2009 May;1788(5):1081-91. doi: 10.1016/j.bbamem.2009.02.004. Epub 2009 Feb 20.

22.

Ionic interactions are essential for TRPV1 C-terminus binding to calmodulin.

Grycova L, Lansky Z, Friedlova E, Obsilova V, Janouskova H, Obsil T, Teisinger J.

Biochem Biophys Res Commun. 2008 Oct 31;375(4):680-3. doi: 10.1016/j.bbrc.2008.08.094. Epub 2008 Aug 26.

PMID:
18755153
23.

The role of proline residues in the structure and function of human MT2 melatonin receptor.

Mazna P, Grycova L, Balik A, Zemkova H, Friedlova E, Obsilova V, Obsil T, Teisinger J.

J Pineal Res. 2008 Nov;45(4):361-72. doi: 10.1111/j.1600-079X.2008.00598.x. Epub 2008 Jun 9.

PMID:
18544139
24.

Subcellular redistribution of trimeric G-proteins--potential mechanism of desensitization of hormone response: internalization, solubilization, down-regulation.

Drastichová Z, Bourová L, Lisý V, Hejnová L, Rudajev V, Stöhr J, Durchánková D, Ostasov P, Teisinger J, Soukup T, Novotný J, Svoboda P.

Physiol Res. 2008;57 Suppl 3:S1-10. Epub 2008 May 13. Review.

25.

14-3-3 proteins: a family of versatile molecular regulators.

Obsilová V, Silhan J, Boura E, Teisinger J, Obsil T.

Physiol Res. 2008;57 Suppl 3:S11-21. Epub 2008 May 13. Review.

26.

The 14-3-3 protein affects the conformation of the regulatory domain of human tyrosine hydroxylase.

Obsilova V, Nedbalkova E, Silhan J, Boura E, Herman P, Vecer J, Sulc M, Teisinger J, Dyda F, Obsil T.

Biochemistry. 2008 Feb 12;47(6):1768-77. doi: 10.1021/bi7019468. Epub 2008 Jan 9.

PMID:
18181650
27.

Functional changes in the vanilloid receptor subtype 1 channel during and after acute desensitization.

Novakova-Tousova K, Vyklicky L, Susankova K, Benedikt J, Samad A, Teisinger J, Vlachova V.

Neuroscience. 2007 Oct 12;149(1):144-54. Epub 2007 Aug 8.

PMID:
17869438
28.

ATP binding site on the C-terminus of the vanilloid receptor.

Grycova L, Lansky Z, Friedlova E, Vlachova V, Kubala M, Obsilova V, Obsil T, Teisinger J.

Arch Biochem Biophys. 2007 Sep 15;465(2):389-98. Epub 2007 Jul 21.

PMID:
17706589
29.

Contribution of the putative inner-pore region to the gating of the transient receptor potential vanilloid subtype 1 channel (TRPV1).

Susankova K, Ettrich R, Vyklicky L, Teisinger J, Vlachova V.

J Neurosci. 2007 Jul 11;27(28):7578-85.

30.

Both the N-terminal loop and wing W2 of the forkhead domain of transcription factor Foxo4 are important for DNA binding.

Boura E, Silhan J, Herman P, Vecer J, Sulc M, Teisinger J, Obsilova V, Obsil T.

J Biol Chem. 2007 Mar 16;282(11):8265-75. Epub 2007 Jan 23.

31.

Ethanol inhibits cold-menthol receptor TRPM8 by modulating its interaction with membrane phosphatidylinositol 4,5-bisphosphate.

Benedikt J, Teisinger J, Vyklicky L, Vlachova V.

J Neurochem. 2007 Jan;100(1):211-24. Epub 2006 Oct 27.

32.

Identification of P2X4 receptor-specific residues contributing to the ivermectin effects on channel deactivation.

Jelínková I, Yan Z, Liang Z, Moonat S, Teisinger J, Stojilkovic SS, Zemková H.

Biochem Biophys Res Commun. 2006 Oct 20;349(2):619-25. Epub 2006 Aug 22.

PMID:
16949036
33.

Reducing and oxidizing agents sensitize heat-activated vanilloid receptor (TRPV1) current.

Susankova K, Tousova K, Vyklicky L, Teisinger J, Vlachova V.

Mol Pharmacol. 2006 Jul;70(1):383-94. Epub 2006 Apr 13.

PMID:
16614139
34.

14-3-3 Protein interacts with nuclear localization sequence of forkhead transcription factor FoxO4.

Obsilova V, Vecer J, Herman P, Pabianova A, Sulc M, Teisinger J, Boura E, Obsil T.

Biochemistry. 2005 Aug 30;44(34):11608-17.

PMID:
16114898
35.

Ligand binding to the human MT2 melatonin receptor: the role of residues in transmembrane domains 3, 6, and 7.

Mazna P, Berka K, Jelinkova I, Balik A, Svoboda P, Obsilova V, Obsil T, Teisinger J.

Biochem Biophys Res Commun. 2005 Jul 8;332(3):726-34.

PMID:
15913560
36.

Molecular modeling of human MT2 melatonin receptor: the role of Val204, Leu272 and Tyr298 in ligand binding.

Mazna P, Obsilova V, Jelinkova I, Balik A, Berka K, Sovova Z, Ettrich R, Svoboda P, Obsil T, Teisinger J.

J Neurochem. 2004 Nov;91(4):836-42. Erratum in: J Neurochem. 2004 Dec;91(6):1505.

37.

The phosphatase activity of the isolated H4-H5 loop of Na+/K+ ATPase resides outside its ATP binding site.

Krumscheid R, Ettrich R, Sovová Z, Susánková K, Lánský Z, Hofbauerová K, Linnertz H, Teisinger J, Amler E, Schoner W.

Eur J Biochem. 2004 Oct;271(19):3923-36.

38.

14-3-3 protein C-terminal stretch occupies ligand binding groove and is displaced by phosphopeptide binding.

Silhan J, Obsilova V, Vecer J, Herman P, Sulc M, Teisinger J, Obsil T.

J Biol Chem. 2004 Nov 19;279(47):49113-9. Epub 2004 Sep 4.

39.

Oxidizing reagent copper-o-phenanthroline is an open channel blocker of the vanilloid receptor TRPV1.

Tousova K, Susankova K, Teisinger J, Vyklicky L, Vlachova V.

Neuropharmacology. 2004 Aug;47(2):273-85.

PMID:
15223306
41.

Biochemistry of transmembrane signaling mediated by trimeric G proteins.

Svoboda P, Teisinger J, Novotný J, Bourová L, Drmota T, Hejnová L, Moravcová Z, Lisý V, Rudajev V, Stöhr J, Vokurková A, Svandová I, Durchánková D.

Physiol Res. 2004;53 Suppl 1:S141-52. Review.

42.

14-3-3zeta C-terminal stretch changes its conformation upon ligand binding and phosphorylation at Thr232.

Obsilova V, Herman P, Vecer J, Sulc M, Teisinger J, Obsil T.

J Biol Chem. 2004 Feb 6;279(6):4531-40. Epub 2003 Nov 12.

43.

ATP-binding is stabilized by a stacking interaction within the binding site of Na+/K+ -ATPase.

Hofbauerová K, Kopecký V Jr, Ettrich R, Kubala M, Teisinger J, Amler E.

Biochem Biophys Res Commun. 2003 Jun 27;306(2):416-20.

PMID:
12804579
44.

Eight amino acids form the ATP recognition site of Na(+)/K(+)-ATPase.

Kubala M, Teisinger J, Ettrich R, Hofbauerová K, Kopecký V Jr, Baumruk V, Krumscheid R, Plásek J, Schoner W, Amler E.

Biochemistry. 2003 Jun 3;42(21):6446-52.

PMID:
12767226
45.

Localization of catalytic active sites in the large cytoplasmic domain of Na+/K+-ATPase.

Krumscheid R, Suánková K, Ettrich R, Teisinger J, Amler E, Schoner W.

Ann N Y Acad Sci. 2003 Apr;986:242-4. No abstract available.

PMID:
12763807
46.

Functional role of C-terminal cytoplasmic tail of rat vanilloid receptor 1.

Vlachová V, Teisinger J, Susánková K, Lyfenko A, Ettrich R, Vyklický L.

J Neurosci. 2003 Feb 15;23(4):1340-50.

47.

Phe(475) and Glu(446) but not Ser(445) participate in ATP-binding to the alpha-subunit of Na(+)/K(+)-ATPase.

Kubala M, Hofbauerová K, Ettrich R, Kopecký V Jr, Krumscheid R, Plásek J, Teisinger J, Schoner W, Amler E.

Biochem Biophys Res Commun. 2002 Sep 13;297(1):154-9.

PMID:
12220524
48.

Reducing agent dithiothreitol facilitates activity of the capsaicin receptor VR-1.

Vyklický L, Lyfenko A, Susánková K, Teisinger J, Vlachová V.

Neuroscience. 2002;111(3):435-41.

PMID:
12031340
49.

Axotomy-induced changes in the properties of NMDA receptor channels in rat spinal cord motoneurons.

Abdrachmanova G, Teisinger J, Vyklický L Jr.

J Physiol. 2002 Jan 1;538(Pt 1):53-63.

50.

Molecular and functional properties of synaptically activated NMDA receptors in neonatal motoneurons in rat spinal cord slices.

Abdrachmanova G, Teisinger J, Vlachová V, Vyklický L Jr.

Eur J Neurosci. 2000 Mar;12(3):955-63.

PMID:
10762325

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