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Items: 42

1.

Metabolic Consequences of T-cell Costimulation in Anticancer Immunity.

Teijeira A, Garasa S, Etxeberria I, Gato-Cañas M, Melero I, Delgoffe GM.

Cancer Immunol Res. 2019 Oct;7(10):1564-1569. doi: 10.1158/2326-6066.CIR-19-0115. Review.

PMID:
31575551
2.

Immunotherapeutic effects of intratumoral nanoplexed poly I:C.

Aznar MA, Planelles L, Perez-Olivares M, Molina C, Garasa S, Etxeberría I, Perez G, Rodriguez I, Bolaños E, Lopez-Casas P, Rodriguez-Ruiz ME, Perez-Gracia JL, Marquez-Rodas I, Teijeira A, Quintero M, Melero I.

J Immunother Cancer. 2019 May 2;7(1):116. doi: 10.1186/s40425-019-0568-2.

3.

Prophylactic TNF blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy.

Perez-Ruiz E, Minute L, Otano I, Alvarez M, Ochoa MC, Belsue V, de Andrea C, Rodriguez-Ruiz ME, Perez-Gracia JL, Marquez-Rodas I, Llacer C, Alvarez M, de Luque V, Molina C, Teijeira A, Berraondo P, Melero I.

Nature. 2019 May;569(7756):428-432. doi: 10.1038/s41586-019-1162-y. Epub 2019 May 1.

PMID:
31043740
4.

The clinical application of cancer immunotherapy based on naturally circulating dendritic cells.

Bol KF, Schreibelt G, Rabold K, Wculek SK, Schwarze JK, Dzionek A, Teijeira A, Kandalaft LE, Romero P, Coukos G, Neyns B, Sancho D, Melero I, de Vries IJM.

J Immunother Cancer. 2019 Apr 18;7(1):109. doi: 10.1186/s40425-019-0580-6. Review.

5.

Dendritic Cells and T Cells Interact Within Murine Afferent Lymphatic Capillaries.

Hunter MC, Teijeira A, Montecchi R, Russo E, Runge P, Kiefer F, Halin C.

Front Immunol. 2019 Mar 22;10:520. doi: 10.3389/fimmu.2019.00520. eCollection 2019.

6.

Intratumoral Immunotherapy with XCL1 and sFlt3L Encoded in Recombinant Semliki Forest Virus-Derived Vectors Fosters Dendritic Cell-Mediated T-cell Cross-Priming.

Sánchez-Paulete AR, Teijeira Á, Quetglas JI, Rodríguez-Ruiz ME, Sánchez-Arráez Á, Labiano S, Etxeberria I, Azpilikueta A, Bolaños E, Ballesteros-Briones MC, Casares N, Quezada SA, Berraondo P, Sancho D, Smerdou C, Melero I.

Cancer Res. 2018 Dec 1;78(23):6643-6654. doi: 10.1158/0008-5472.CAN-18-0933. Epub 2018 Oct 8.

PMID:
30297531
7.

ICAM-1-LFA-1 Dependent CD8+ T-Lymphocyte Aggregation in Tumor Tissue Prevents Recirculation to Draining Lymph Nodes.

Yanguas A, Garasa S, Teijeira Á, Aubá C, Melero I, Rouzaut A.

Front Immunol. 2018 Sep 12;9:2084. doi: 10.3389/fimmu.2018.02084. eCollection 2018.

8.

Liquid Biopsy Biomarkers in Bladder Cancer: A Current Need for Patient Diagnosis and Monitoring.

Lodewijk I, Dueñas M, Rubio C, Munera-Maravilla E, Segovia C, Bernardini A, Teijeira A, Paramio JM, Suárez-Cabrera C.

Int J Mol Sci. 2018 Aug 24;19(9). pii: E2514. doi: 10.3390/ijms19092514. Review.

9.

Epistatic Oncogenic Interactions Determine Cancer Susceptibility to Immunotherapy.

Etxeberria I, Teijeira A, Montuenga LM, Berraondo P, Melero I.

Cancer Discov. 2018 Jul;8(7):794-796. doi: 10.1158/2159-8290.CD-18-0573.

10.

Mitochondrial Morphological and Functional Reprogramming Following CD137 (4-1BB) Costimulation.

Teijeira A, Labiano S, Garasa S, Etxeberria I, Santamaría E, Rouzaut A, Enamorado M, Azpilikueta A, Inoges S, Bolaños E, Aznar MA, Sánchez-Paulete AR, Sancho D, Melero I.

Cancer Immunol Res. 2018 Jul;6(7):798-811. doi: 10.1158/2326-6066.CIR-17-0767. Epub 2018 Apr 20.

11.

Deubiquitinases A20 and CYLD modulate costimulatory signaling via CD137 (4-1BB).

Azpilikueta A, Bolaños E, Lang V, Labiano S, Aznar MA, Etxeberria I, Teijeira A, Rodriguez-Ruiz ME, Perez-Gracia JL, Jure-Kunkel M, Zapata JM, Rodriguez MS, Melero I.

Oncoimmunology. 2017 Sep 21;7(1):e1368605. doi: 10.1080/2162402X.2017.1368605. eCollection 2017.

12.

Cancer immunotherapy full speed ahead.

Melero I, Navarro B, Teijeira A, Coukos G.

Ann Oncol. 2017 Dec 1;28(suppl_12):xii1-xii2. doi: 10.1093/annonc/mdx739. No abstract available.

PMID:
29253117
13.

Antigen cross-presentation and T-cell cross-priming in cancer immunology and immunotherapy.

Sánchez-Paulete AR, Teijeira A, Cueto FJ, Garasa S, Pérez-Gracia JL, Sánchez-Arráez A, Sancho D, Melero I.

Ann Oncol. 2017 Dec 1;28(suppl_12):xii74. doi: 10.1093/annonc/mdx727. No abstract available.

PMID:
29253116
14.

Antigen cross-presentation and T-cell cross-priming in cancer immunology and immunotherapy.

Sánchez-Paulete AR, Teijeira A, Cueto FJ, Garasa S, Pérez-Gracia JL, Sánchez-Arráez A, Sancho D, Melero I.

Ann Oncol. 2017 Dec 1;28(suppl_12):xii44-xii55. doi: 10.1093/annonc/mdx237. Erratum in: Ann Oncol. 2017 Dec 1;28(suppl_12):xii74.

PMID:
28945841
15.

BMP4 Induces M2 Macrophage Polarization and Favors Tumor Progression in Bladder Cancer.

Martínez VG, Rubio C, Martínez-Fernández M, Segovia C, López-Calderón F, Garín MI, Teijeira A, Munera-Maravilla E, Varas A, Sacedón R, Guerrero F, Villacampa F, de la Rosa F, Castellano D, López-Collazo E, Paramio JM, Vicente Á, Dueñas M.

Clin Cancer Res. 2017 Dec 1;23(23):7388-7399. doi: 10.1158/1078-0432.CCR-17-1004. Epub 2017 Sep 19.

16.

Interleukin-8 in cancer pathogenesis, treatment and follow-up.

Alfaro C, Sanmamed MF, Rodríguez-Ruiz ME, Teijeira Á, Oñate C, González Á, Ponz M, Schalper KA, Pérez-Gracia JL, Melero I.

Cancer Treat Rev. 2017 Nov;60:24-31. doi: 10.1016/j.ctrv.2017.08.004. Epub 2017 Aug 31. Review.

PMID:
28866366
17.

Microinjection for the ex Vivo Modification of Cells with Artificial Organelles.

Tiefenboeck P, Kim JA, Trunk F, Eicher T, Russo E, Teijeira A, Halin C, Leroux JC.

ACS Nano. 2017 Aug 22;11(8):7758-7769. doi: 10.1021/acsnano.7b01404. Epub 2017 Aug 11.

PMID:
28777538
18.

Cellular immunotherapies for cancer.

Berraondo P, Labiano S, Minute L, Etxeberria I, Vasquez M, Sanchez-Arraez A, Teijeira A, Melero I.

Oncoimmunology. 2017 May 2;6(5):e1306619. doi: 10.1080/2162402X.2017.1306619. eCollection 2017. Review.

19.

CD69 is a direct HIF-1α target gene in hypoxia as a mechanism enhancing expression on tumor-infiltrating T lymphocytes.

Labiano S, Meléndez-Rodríguez F, Palazón A, Teijeira Á, Garasa S, Etxeberria I, Aznar MÁ, Sánchez-Paulete AR, Azpilikueta A, Bolaños E, Molina C, de la Fuente H, Maiso P, Sánchez-Madrid F, de Landázuri MO, Aragonés J, Melero I.

Oncoimmunology. 2017 Jan 19;6(4):e1283468. doi: 10.1080/2162402X.2017.1283468. eCollection 2017.

20.

T Cell Migration from Inflamed Skin to Draining Lymph Nodes Requires Intralymphatic Crawling Supported by ICAM-1/LFA-1 Interactions.

Teijeira A, Hunter MC, Russo E, Proulx ST, Frei T, Debes GF, Coles M, Melero I, Detmar M, Rouzaut A, Halin C.

Cell Rep. 2017 Jan 24;18(4):857-865. doi: 10.1016/j.celrep.2016.12.078.

21.

Intercellular Adhesion Molecule-1 and Vascular Cell Adhesion Molecule Are Induced by Ionizing Radiation on Lymphatic Endothelium.

Rodriguez-Ruiz ME, Garasa S, Rodriguez I, Solorzano JL, Barbes B, Yanguas A, Teijeira A, Etxeberria I, Aristu JJ, Halin C, Melero I, Rouzaut A.

Int J Radiat Oncol Biol Phys. 2017 Feb 1;97(2):389-400. doi: 10.1016/j.ijrobp.2016.10.043. Epub 2016 Nov 7.

PMID:
28068246
22.

T Cell Trafficking through Lymphatic Vessels.

Hunter MC, Teijeira A, Halin C.

Front Immunol. 2016 Dec 21;7:613. doi: 10.3389/fimmu.2016.00613. eCollection 2016. Review.

23.

IL-1 Coordinates the Neutrophil Response to C. albicans in the Oral Mucosa.

Altmeier S, Toska A, Sparber F, Teijeira A, Halin C, LeibundGut-Landmann S.

PLoS Pathog. 2016 Sep 15;12(9):e1005882. doi: 10.1371/journal.ppat.1005882. eCollection 2016 Sep.

24.

Immunotherapy of Cancer Visualized by Live Microscopy: Seeing Is Believing.

Teijeira A, Etxeberria I, Ponz-Sarvise M, Melero I.

Clin Cancer Res. 2016 Sep 1;22(17):4277-9. doi: 10.1158/1078-0432.CCR-16-1072. Epub 2016 Jun 21.

25.

Cancer Immunosurveillance Caught in the Act.

Berraondo P, Teijeira A, Melero I.

Immunity. 2016 Mar 15;44(3):525-526. doi: 10.1016/j.immuni.2016.03.004.

26.

Tumor-Produced Interleukin-8 Attracts Human Myeloid-Derived Suppressor Cells and Elicits Extrusion of Neutrophil Extracellular Traps (NETs).

Alfaro C, Teijeira A, Oñate C, Pérez G, Sanmamed MF, Andueza MP, Alignani D, Labiano S, Azpilikueta A, Rodriguez-Paulete A, Garasa S, Fusco JP, Aznar A, Inogés S, De Pizzol M, Allegretti M, Medina-Echeverz J, Berraondo P, Perez-Gracia JL, Melero I.

Clin Cancer Res. 2016 Aug 1;22(15):3924-36. doi: 10.1158/1078-0432.CCR-15-2463. Epub 2016 Mar 8.

27.

Intralymphatic CCL21 Promotes Tissue Egress of Dendritic Cells through Afferent Lymphatic Vessels.

Russo E, Teijeira A, Vaahtomeri K, Willrodt AH, Bloch JS, Nitschké M, Santambrogio L, Kerjaschki D, Sixt M, Halin C.

Cell Rep. 2016 Feb 23;14(7):1723-1734. doi: 10.1016/j.celrep.2016.01.048. Epub 2016 Feb 11.

28.

Successful Immunotherapy against a Transplantable Mouse Squamous Lung Carcinoma with Anti-PD-1 and Anti-CD137 Monoclonal Antibodies.

Azpilikueta A, Agorreta J, Labiano S, Pérez-Gracia JL, Sánchez-Paulete AR, Aznar MA, Ajona D, Gil-Bazo I, Larrayoz M, Teijeira A, Rodriguez-Ruiz ME, Pio R, Montuenga LM, Melero I.

J Thorac Oncol. 2016 Apr;11(4):524-36. doi: 10.1016/j.jtho.2016.01.013. Epub 2016 Feb 1.

29.

Editorial: Breaching their way through: Neutrophils destroy intercellular junctions to transmigrate rapidly across lymphatic endothelium.

Teijeira A, Halin C.

J Leukoc Biol. 2015 Dec;98(6):880-2. doi: 10.1189/jlb.3CE0615-273. No abstract available.

PMID:
26628638
30.

Focusing and sustaining the antitumor CTL effector killer response by agonist anti-CD137 mAb.

Weigelin B, Bolaños E, Teijeira A, Martinez-Forero I, Labiano S, Azpilikueta A, Morales-Kastresana A, Quetglas JI, Wagena E, Sánchez-Paulete AR, Chen L, Friedl P, Melero I.

Proc Natl Acad Sci U S A. 2015 Jun 16;112(24):7551-6. doi: 10.1073/pnas.1506357112. Epub 2015 Jun 1.

31.

A transgenic Prox1-Cre-tdTomato reporter mouse for lymphatic vessel research.

Bianchi R, Teijeira A, Proulx ST, Christiansen AJ, Seidel CD, Rülicke T, Mäkinen T, Hägerling R, Halin C, Detmar M.

PLoS One. 2015 Apr 7;10(4):e0122976. doi: 10.1371/journal.pone.0122976. eCollection 2015.

32.

Taking the lymphatic route: dendritic cell migration to draining lymph nodes.

Teijeira A, Russo E, Halin C.

Semin Immunopathol. 2014 Mar;36(2):261-74. doi: 10.1007/s00281-013-0410-8. Epub 2014 Jan 9. Review.

PMID:
24402708
33.

Initial afferent lymphatic vessels controlling outbound leukocyte traffic from skin to lymph nodes.

Teijeira A, Rouzaut A, Melero I.

Front Immunol. 2013 Dec 9;4:433. doi: 10.3389/fimmu.2013.00433. Review.

34.

T cell costimulation with anti-CD137 monoclonal antibodies is mediated by K63-polyubiquitin-dependent signals from endosomes.

Martinez-Forero I, Azpilikueta A, Bolaños-Mateo E, Nistal-Villan E, Palazon A, Teijeira A, Perez-Chacon G, Morales-Kastresana A, Murillo O, Jure-Kunkel M, Zapata JM, Melero I.

J Immunol. 2013 Jun 15;190(12):6694-706. doi: 10.4049/jimmunol.1203010. Epub 2013 May 20.

35.

Lymphatic endothelium forms integrin-engaging 3D structures during DC transit across inflamed lymphatic vessels.

Teijeira A, Garasa S, Peláez R, Azpilikueta A, Ochoa C, Marré D, Rodrigues M, Alfaro C, Aubá C, Valitutti S, Melero I, Rouzaut A.

J Invest Dermatol. 2013 Sep;133(9):2276-85. doi: 10.1038/jid.2013.152. Epub 2013 Mar 25.

36.

Phosphorylated tubulin adaptor protein CRMP-2 as prognostic marker and candidate therapeutic target for NSCLC.

Oliemuller E, Peláez R, Garasa S, Pajares MJ, Agorreta J, Pío R, Montuenga LM, Teijeira A, Llanos S, Rouzaut A.

Int J Cancer. 2013 May 1;132(9):1986-95. doi: 10.1002/ijc.27881. Epub 2012 Oct 20.

37.

The HIF-1α hypoxia response in tumor-infiltrating T lymphocytes induces functional CD137 (4-1BB) for immunotherapy.

Palazón A, Martínez-Forero I, Teijeira A, Morales-Kastresana A, Alfaro C, Sanmamed MF, Perez-Gracia JL, Peñuelas I, Hervás-Stubbs S, Rouzaut A, de Landázuri MO, Jure-Kunkel M, Aragonés J, Melero I.

Cancer Discov. 2012 Jul;2(7):608-23. doi: 10.1158/2159-8290.CD-11-0314. Epub 2012 Jun 19.

38.

CD137 on inflamed lymphatic endothelial cells enhances CCL21-guided migration of dendritic cells.

Teijeira Á, Palazón A, Garasa S, Marré D, Aubá C, Rogel A, Murillo O, Martínez-Forero I, Lang F, Melero I, Rouzaut A.

FASEB J. 2012 Aug;26(8):3380-92. doi: 10.1096/fj.11-201061. Epub 2012 May 16.

PMID:
22593548
39.

Agonist anti-CD137 mAb act on tumor endothelial cells to enhance recruitment of activated T lymphocytes.

Palazón A, Teijeira A, Martínez-Forero I, Hervás-Stubbs S, Roncal C, Peñuelas I, Dubrot J, Morales-Kastresana A, Pérez-Gracia JL, Ochoa MC, Ochoa-Callejero L, Martínez A, Luque A, Dinchuk J, Rouzaut A, Jure-Kunkel M, Melero I.

Cancer Res. 2011 Feb 1;71(3):801-11. doi: 10.1158/0008-5472.CAN-10-1733. Epub 2011 Jan 25.

40.

Dendritic cells adhere to and transmigrate across lymphatic endothelium in response to IFN-α.

Rouzaut A, Garasa S, Teijeira A, González I, Martinez-Forero I, Suarez N, Larrea E, Alfaro C, Palazón A, Dubrot J, Hervás-Stubbs S, Melero I.

Eur J Immunol. 2010 Nov;40(11):3054-63. doi: 10.1002/eji.201040523. Epub 2010 Oct 27.

41.

Repetitive nicotine exposure leads to a more malignant and metastasis-prone phenotype of SCLC: a molecular insight into the importance of quitting smoking during treatment.

Martínez-García E, Irigoyen M, González-Moreno O, Corrales L, Teijeira A, Salvo E, Rouzaut A.

Toxicol Sci. 2010 Aug;116(2):467-76. doi: 10.1093/toxsci/kfq138. Epub 2010 May 10.

42.

Intratumoral injection of interferon-α and systemic delivery of agonist anti-CD137 monoclonal antibodies synergize for immunotherapy.

Dubrot J, Palazón A, Alfaro C, Azpilikueta A, Ochoa MC, Rouzaut A, Martinez-Forero I, Teijeira A, Berraondo P, Le Bon A, Hervás-Stubbs S, Melero I.

Int J Cancer. 2011 Jan 1;128(1):105-18. doi: 10.1002/ijc.25333.

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