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Items: 31


Antibody Engineering for Optimized Immunotherapy in Alzheimer's Disease.

Sumner IL, Edwards RA, Asuni AA, Teeling JL.

Front Neurosci. 2018 Apr 23;12:254. doi: 10.3389/fnins.2018.00254. eCollection 2018. Review.


The long-lived Octodon degus as a rodent drug discovery model for Alzheimer's and other age-related diseases.

Hurley MJ, Deacon RMJ, Beyer K, Ioannou E, Ibáñez A, Teeling JL, Cogram P.

Pharmacol Ther. 2018 Aug;188:36-44. doi: 10.1016/j.pharmthera.2018.03.001. Epub 2018 Mar 4. Review.


Cathepsin B plays a critical role in inducing Alzheimer's disease-like phenotypes following chronic systemic exposure to lipopolysaccharide from Porphyromonas gingivalis in mice.

Wu Z, Ni J, Liu Y, Teeling JL, Takayama F, Collcutt A, Ibbett P, Nakanishi H.

Brain Behav Immun. 2017 Oct;65:350-361. doi: 10.1016/j.bbi.2017.06.002. Epub 2017 Jun 10.


STING Activation Reverses Lymphoma-Mediated Resistance to Antibody Immunotherapy.

Dahal LN, Dou L, Hussain K, Liu R, Earley A, Cox KL, Murinello S, Tracy I, Forconi F, Steele AJ, Duriez PJ, Gomez-Nicola D, Teeling JL, Glennie MJ, Cragg MS, Beers SA.

Cancer Res. 2017 Jul 1;77(13):3619-3631. doi: 10.1158/0008-5472.CAN-16-2784. Epub 2017 May 16.


Comparing the efficacy and neuroinflammatory potential of three anti-abeta antibodies.

Fuller JP, Stavenhagen JB, Christensen S, Kartberg F, Glennie MJ, Teeling JL.

Acta Neuropathol. 2015 Nov;130(5):699-711. doi: 10.1007/s00401-015-1484-2. Epub 2015 Oct 3.


Low-grade inflammation, diet composition and health: current research evidence and its translation.

Minihane AM, Vinoy S, Russell WR, Baka A, Roche HM, Tuohy KM, Teeling JL, Blaak EE, Fenech M, Vauzour D, McArdle HJ, Kremer BH, Sterkman L, Vafeiadou K, Benedetti MM, Williams CM, Calder PC.

Br J Nutr. 2015 Oct 14;114(7):999-1012. doi: 10.1017/S0007114515002093. Epub 2015 Jul 31. Review.


New roles for Fc receptors in neurodegeneration-the impact on Immunotherapy for Alzheimer's Disease.

Fuller JP, Stavenhagen JB, Teeling JL.

Front Neurosci. 2014 Aug 21;8:235. doi: 10.3389/fnins.2014.00235. eCollection 2014. Review.


Fcγ receptor upregulation is associated with immune complex inflammation in the mouse retina and early age-related macular degeneration.

Murinello S, Mullins RF, Lotery AJ, Perry VH, Teeling JL.

Invest Ophthalmol Vis Sci. 2014 Jan 13;55(1):247-58. doi: 10.1167/iovs.13-11821.


Immune complex formation impairs the elimination of solutes from the brain: implications for immunotherapy in Alzheimer's disease.

Carare RO, Teeling JL, Hawkes CA, Püntener U, Weller RO, Nicoll JA, Perry VH.

Acta Neuropathol Commun. 2013 Aug 9;1:48. doi: 10.1186/2051-5960-1-48.


Long-term impact of systemic bacterial infection on the cerebral vasculature and microglia.

Püntener U, Booth SG, Perry VH, Teeling JL.

J Neuroinflammation. 2012 Jun 27;9:146. doi: 10.1186/1742-2094-9-146.


Intracerebral immune complex formation induces inflammation in the brain that depends on Fc receptor interaction.

Teeling JL, Carare RO, Glennie MJ, Perry VH.

Acta Neuropathol. 2012 Oct;124(4):479-90. doi: 10.1007/s00401-012-0995-3. Epub 2012 May 18.


The intrathecal CD163-haptoglobin-hemoglobin scavenging system in subarachnoid hemorrhage.

Galea J, Cruickshank G, Teeling JL, Boche D, Garland P, Perry VH, Galea I.

J Neurochem. 2012 Jun;121(5):785-92. doi: 10.1111/j.1471-4159.2012.07716.x. Epub 2012 Mar 30.


Age related changes in microglial phenotype vary between CNS regions: grey versus white matter differences.

Hart AD, Wyttenbach A, Perry VH, Teeling JL.

Brain Behav Immun. 2012 Jul;26(5):754-65. doi: 10.1016/j.bbi.2011.11.006. Epub 2011 Dec 2.


Mouse maternal systemic inflammation at the zygote stage causes blunted cytokine responsiveness in lipopolysaccharide-challenged adult offspring.

Williams CL, Teeling JL, Perry VH, Fleming TP.

BMC Biol. 2011 Jul 19;9:49. doi: 10.1186/1741-7007-9-49.


Systemic inflammation modulates Fc receptor expression on microglia during chronic neurodegeneration.

Lunnon K, Teeling JL, Tutt AL, Cragg MS, Glennie MJ, Perry VH.

J Immunol. 2011 Jun 15;186(12):7215-24. doi: 10.4049/jimmunol.0903833. Epub 2011 May 13.


Phosphorylation of RIG-I by casein kinase II inhibits its antiviral response.

Sun Z, Ren H, Liu Y, Teeling JL, Gu J.

J Virol. 2011 Jan;85(2):1036-47. doi: 10.1128/JVI.01734-10. Epub 2010 Nov 10.


The effect of non-steroidal anti-inflammatory agents on behavioural changes and cytokine production following systemic inflammation: Implications for a role of COX-1.

Teeling JL, Cunningham C, Newman TA, Perry VH.

Brain Behav Immun. 2010 Mar;24(3):409-19. doi: 10.1016/j.bbi.2009.11.006. Epub 2009 Dec 4.


Systemic infection and inflammation in acute CNS injury and chronic neurodegeneration: underlying mechanisms.

Teeling JL, Perry VH.

Neuroscience. 2009 Feb 6;158(3):1062-73. doi: 10.1016/j.neuroscience.2008.07.031. Epub 2008 Jul 25. Review.


CD11c provides an effective immunotarget for the generation of both CD4 and CD8 T cell responses.

Castro FV, Tutt AL, White AL, Teeling JL, James S, French RR, Glennie MJ.

Eur J Immunol. 2008 Aug;38(8):2263-73. doi: 10.1002/eji.200838302.


Retinoic acid-inducible gene-I mediates late phase induction of TNF-alpha by lipopolysaccharide.

Wang J, Wu S, Jin X, Li M, Chen S, Teeling JL, Perry VH, Gu J.

J Immunol. 2008 Jun 15;180(12):8011-9.


Sub-pyrogenic systemic inflammation impacts on brain and behavior, independent of cytokines.

Teeling JL, Felton LM, Deacon RM, Cunningham C, Rawlins JN, Perry VH.

Brain Behav Immun. 2007 Aug;21(6):836-50. Epub 2007 Mar 23.


The biological activity of human CD20 monoclonal antibodies is linked to unique epitopes on CD20.

Teeling JL, Mackus WJ, Wiegman LJ, van den Brakel JH, Beers SA, French RR, van Meerten T, Ebeling S, Vink T, Slootstra JW, Parren PW, Glennie MJ, van de Winkel JG.

J Immunol. 2006 Jul 1;177(1):362-71.


A novel human CD32 mAb blocks experimental immune haemolytic anaemia in FcgammaRIIA transgenic mice.

van Royen-Kerkhof A, Sanders EA, Walraven V, Voorhorst-Ogink M, Saeland E, Teeling JL, Gerritsen A, van Dijk MA, Kuis W, Rijkers GT, Vitale L, Keler T, McKenzie SE, Leusen JH, van de Winkel JG.

Br J Haematol. 2005 Jul;130(1):130-7.


Monomeric IgG in intravenous Ig preparations is a functional antagonist of FcgammaRII and FcgammaRIIIb.

van Mirre E, Teeling JL, van der Meer JW, Bleeker WK, Hack CE.

J Immunol. 2004 Jul 1;173(1):332-9.


Characterization of new human CD20 monoclonal antibodies with potent cytolytic activity against non-Hodgkin lymphomas.

Teeling JL, French RR, Cragg MS, van den Brakel J, Pluyter M, Huang H, Chan C, Parren PW, Hack CE, Dechant M, Valerius T, van de Winkel JG, Glennie MJ.

Blood. 2004 Sep 15;104(6):1793-800. Epub 2004 Jun 1.


CD20-induced lymphoma cell death is independent of both caspases and its redistribution into triton X-100 insoluble membrane rafts.

Chan HT, Hughes D, French RR, Tutt AL, Walshe CA, Teeling JL, Glennie MJ, Cragg MS.

Cancer Res. 2003 Sep 1;63(17):5480-9.


Therapeutic efficacy of intravenous immunoglobulin preparations depends on the immunoglobulin G dimers: studies in experimental immune thrombocytopenia.

Teeling JL, Jansen-Hendriks T, Kuijpers TW, de Haas M, van de Winkel JG, Hack CE, Bleeker WK.

Blood. 2001 Aug 15;98(4):1095-9.


Intravenous immunoglobulin preparations induce mild activation of neutrophils in vivo via triggering of macrophages--studies in a rat model.

Teeling JL, Bleeker WK, Rigter GM, van Rooijen N, Kuijpers TW, Hack CE.

Br J Haematol. 2001 Mar;112(4):1031-40.


Vasoactive side effects of intravenous immunoglobulin preparations in a rat model and their treatment with recombinant platelet-activating factor acetylhydrolase.

Bleeker WK, Teeling JL, Verhoeven AJ, Rigter GM, Agterberg J, Tool AT, Koenderman AH, Kuijpers TW, Hack CE.

Blood. 2000 Mar 1;95(5):1856-61.


Human intravenous immunoglobulin (IVIG) preparations degranulate human neutrophils in vitro.

Teeling JL, De Groot ER, Eerenberg AJ, Bleeker WK, Van Mierlo G, Aarden LA, Hack CE.

Clin Exp Immunol. 1998 Nov;114(2):264-70.

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