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Does time to adjuvant chemotherapy (TTC) affect outcomes in patients with triple-negative breast cancer?

Pomponio MK, Keele LJ, Fox KR, Clark AS, Matro JM, Shulman LN, Tchou JC.

Breast Cancer Res Treat. 2019 Aug;177(1):137-143. doi: 10.1007/s10549-019-05282-0. Epub 2019 May 22.


Impact of long-term lipid-lowering therapy on clinical outcomes in breast cancer.

Li YR, Ro V, Steel L, Carrigan E, Nguyen J, Williams A, So A, Tchou J.

Breast Cancer Res Treat. 2019 Aug;176(3):669-677. doi: 10.1007/s10549-019-05267-z. Epub 2019 May 13.


Microglandular Adenosis: A Possible Non-Obligate Precursor to Breast Carcinoma With Potential to Either Luminal-Type or Basal-Type Differentiation.

Damron AT, Korhonen K, Zuckerman S, Tchou J, Dumoff KL, Bleiweiss IJ, Nayak A.

Int J Surg Pathol. 2019 Oct;27(7):781-787. doi: 10.1177/1066896919845493. Epub 2019 May 2.


Clinical characteristics and outcomes of benign, atypical, and malignant breast adenomyoepithelioma: a single institution's experience.

Wiens N, Hoffman DI, Huang CY, Nayak A, Tchou J.

Am J Surg. 2019 Apr 1. pii: S0002-9610(19)30363-0. doi: 10.1016/j.amjsurg.2019.03.026. [Epub ahead of print]


Breast-conserving surgery for pure non-classic lobular carcinoma in situ: A single institution's experience.

Hoffman DI, Zhang PJ, Tchou J.

Surg Oncol. 2019 Mar;28:190-194. doi: 10.1016/j.suronc.2019.01.009. Epub 2019 Jan 29.


Dickkopf-3 links HSF1 and YAP/TAZ signalling to control aggressive behaviours in cancer-associated fibroblasts.

Ferrari N, Ranftl R, Chicherova I, Slaven ND, Moeendarbary E, Farrugia AJ, Lam M, Semiannikova M, Westergaard MCW, Tchou J, Magnani L, Calvo F.

Nat Commun. 2019 Jan 10;10(1):130. doi: 10.1038/s41467-018-07987-0.


Overall survival is similar between women who seek care at one or more institutions after diagnosis of operable breast cancer in the community.

Williams AD, So A, Tchou J.

Surg Oncol. 2018 Sep;27(3):387-391. doi: 10.1016/j.suronc.2018.05.020. Epub 2018 May 26.


Quality of life and sexual well-being after nipple sparing mastectomy: A matched comparison of patients using the breast Q.

Yoon-Flannery K, DeStefano LM, De La Cruz LM, Fisher CS, Lin LY, Coffua LS, Mustafa RE, Sataloff DM, Tchou JC, Brooks AD.

J Surg Oncol. 2018 Jul;118(1):238-242. doi: 10.1002/jso.25107. Epub 2018 Aug 16.


The impact of aspirin use on breast cancer subtype and clinical course.

Williams AD, Li YR, So A, Steel L, Carrigan E, Ro V, Nguyen J, Tchou J.

J Surg Res. 2018 Oct;230:71-79. doi: 10.1016/j.jss.2018.04.040. Epub 2018 May 25.


Gestational Gigantomastia Complicated by PTHrP-Mediated Hypercalcemia.

Modarressi T, Levine MA, Tchou J, Khan AN.

J Clin Endocrinol Metab. 2018 Sep 1;103(9):3124-3130. doi: 10.1210/jc.2018-01181.


Is Age Trumping Genetic Profiling in Clinical Practice? Relationship of Chemotherapy Recommendation and Oncotype DX Recurrence Score in Patients Aged < 50 Years versus ≥ 50 Years, and Trends Over Time.

Williams AD, Reyes SA, Arlow RL, Tchou J, De La Cruz LM.

Ann Surg Oncol. 2018 Oct;25(10):2875-2883. doi: 10.1245/s10434-018-6600-9. Epub 2018 Jun 29.


Immunotherapy for Breast Cancer: Current and Future Strategies.

Williams AD, Payne KK, Posey AD Jr, Hill C, Conejo-Garcia J, June CH, Tchou J.

Curr Surg Rep. 2017 Dec;5. pii: 31. Epub 2017 Oct 10.


Obesity, Metabolic Syndrome, and Breast Cancer: From Prevention to Intervention.

Li YR, Ro V, Tchou JC.

Curr Surg Rep. 2018 Mar;6(3). pii: 7. doi: 10.1007/s40137-018-0204-y. Epub 2018 Feb 24.


The impact of preoperative magnetic resonance imaging and lumpectomy cavity shavings on re-excision rate in pure ductal carcinoma in situ-A single institution's experience.

So A, De La Cruz LM, Williams AD, Bahng J, Liao G, McDonald ES, Fisher CS, Czerniecki BJ, Sataloff D, Tchou J.

J Surg Oncol. 2018 Mar;117(4):558-566. doi: 10.1002/jso.24890. Epub 2017 Nov 11.


Safety and Efficacy of Intratumoral Injections of Chimeric Antigen Receptor (CAR) T Cells in Metastatic Breast Cancer.

Tchou J, Zhao Y, Levine BL, Zhang PJ, Davis MM, Melenhorst JJ, Kulikovskaya I, Brennan AL, Liu X, Lacey SF, Posey AD Jr, Williams AD, So A, Conejo-Garcia JR, Plesa G, Young RM, McGettigan S, Campbell J, Pierce RH, Matro JM, DeMichele AM, Clark AS, Cooper LJ, Schuchter LM, Vonderheide RH, June CH.

Cancer Immunol Res. 2017 Dec;5(12):1152-1161. doi: 10.1158/2326-6066.CIR-17-0189. Epub 2017 Nov 6.


Oncologic Safety of Prophylactic Nipple-Sparing Mastectomy in a Population With BRCA Mutations: A Multi-institutional Study.

Jakub JW, Peled AW, Gray RJ, Greenup RA, Kiluk JV, Sacchini V, McLaughlin SA, Tchou JC, Vierkant RA, Degnim AC, Willey S.

JAMA Surg. 2018 Feb 1;153(2):123-129. doi: 10.1001/jamasurg.2017.3422.


Evaluating the Risk of Upstaging HER2-Positive DCIS to Invasive Breast Cancer.

Mustafa RE, DeStefano LM, Bahng J, Yoon-Flannery K, Fisher CS, Zhang PJ, Tchou J, Czerniecki BJ, De La Cruz LM.

Ann Surg Oncol. 2017 Oct;24(10):2999-3003. doi: 10.1245/s10434-017-5941-0. Epub 2017 Aug 1.


Exosome RNA Unshielding Couples Stromal Activation to Pattern Recognition Receptor Signaling in Cancer.

Nabet BY, Qiu Y, Shabason JE, Wu TJ, Yoon T, Kim BC, Benci JL, DeMichele AM, Tchou J, Marcotrigiano J, Minn AJ.

Cell. 2017 Jul 13;170(2):352-366.e13. doi: 10.1016/j.cell.2017.06.031.


Mammographic breast density decreases after bariatric surgery.

Williams AD, So A, Synnestvedt M, Tewksbury CM, Kontos D, Hsiehm MK, Pantalone L, Conant EF, Schnall M, Dumon K, Williams N, Tchou J.

Breast Cancer Res Treat. 2017 Oct;165(3):565-572. doi: 10.1007/s10549-017-4361-y. Epub 2017 Jun 28.


Longitudinal optical monitoring of blood flow in breast tumors during neoadjuvant chemotherapy.

Cochran JM, Chung SH, Leproux A, Baker WB, Busch DR, DeMichele AM, Tchou J, Tromberg BJ, Yodh AG.

Phys Med Biol. 2017 Jun 21;62(12):4637-4653. doi: 10.1088/1361-6560/aa6cef. Epub 2017 Apr 12.


Breast cancer subtype distribution is different in normal weight, overweight, and obese women.

Gershuni V, Li YR, Williams AD, So A, Steel L, Carrigan E, Tchou J.

Breast Cancer Res Treat. 2017 Jun;163(2):375-381. doi: 10.1007/s10549-017-4192-x. Epub 2017 Mar 14.


Optical redox imaging indices discriminate human breast cancer from normal tissues.

Xu HN, Tchou J, Feng M, Zhao H, Li LZ.

J Biomed Opt. 2016 Nov 1;21(11):114003. doi: 10.1117/1.JBO.21.11.114003.


Trametinib Drives T-cell-Dependent Control of KRAS-Mutated Tumors by Inhibiting Pathological Myelopoiesis.

Allegrezza MJ, Rutkowski MR, Stephen TL, Svoronos N, Perales-Puchalt A, Nguyen JM, Payne KK, Singhal S, Eruslanov EB, Tchou J, Conejo-Garcia JR.

Cancer Res. 2016 Nov 1;76(21):6253-6265.


Reliable prediction of postmastectomy lymphedema: The Risk Assessment Tool Evaluating Lymphedema.

Basta MN, Wu LC, Kanchwala SK, Serletti JM, Tchou JC, Kovach SJ, Fosnot J, Fischer JP.

Am J Surg. 2017 Jun;213(6):1125-1133.e1. doi: 10.1016/j.amjsurg.2016.08.016. Epub 2016 Sep 7.


Tumor Cell-Independent Estrogen Signaling Drives Disease Progression through Mobilization of Myeloid-Derived Suppressor Cells.

Svoronos N, Perales-Puchalt A, Allegrezza MJ, Rutkowski MR, Payne KK, Tesone AJ, Nguyen JM, Curiel TJ, Cadungog MG, Singhal S, Eruslanov EB, Zhang P, Tchou J, Zhang R, Conejo-Garcia JR.

Cancer Discov. 2017 Jan;7(1):72-85. doi: 10.1158/2159-8290.CD-16-0502. Epub 2016 Sep 30.


Follicle-Stimulating Hormone Receptor Is Expressed by Most Ovarian Cancer Subtypes and Is a Safe and Effective Immunotherapeutic Target.

Perales-Puchalt A, Svoronos N, Rutkowski MR, Allegrezza MJ, Tesone AJ, Payne KK, Wickramasinghe J, Nguyen JM, O'Brien SW, Gumireddy K, Huang Q, Cadungog MG, Connolly DC, Tchou J, Curiel TJ, Conejo-Garcia JR.

Clin Cancer Res. 2017 Jan 15;23(2):441-453. doi: 10.1158/1078-0432.CCR-16-0492. Epub 2016 Jul 19.


Outcomes After Oncoplastic Breast-Conserving Surgery in Breast Cancer Patients: A Systematic Literature Review.

De La Cruz L, Blankenship SA, Chatterjee A, Geha R, Nocera N, Czerniecki BJ, Tchou J, Fisher CS.

Ann Surg Oncol. 2016 Oct;23(10):3247-58. doi: 10.1245/s10434-016-5313-1. Epub 2016 Jun 29. Review.


Obesity and Breast Cancer: A Complex Relationship.

Gershuni VM, Ahima RS, Tchou J.

Curr Surg Rep. 2016 Apr;4. pii: 14. doi: 10.1007/s40137-016-0134-5. Epub 2016 Mar 21.


IL15 Agonists Overcome the Immunosuppressive Effects of MEK Inhibitors.

Allegrezza MJ, Rutkowski MR, Stephen TL, Svoronos N, Tesone AJ, Perales-Puchalt A, Nguyen JM, Sarmin F, Sheen MR, Jeng EK, Tchou J, Wong HC, Fiering SN, Conejo-Garcia JR.

Cancer Res. 2016 May 1;76(9):2561-72. doi: 10.1158/0008-5472.CAN-15-2808. Epub 2016 Mar 15.


Treatment and Long-Term Risks for Patients With a Diagnosis of Ductal Carcinoma In Situ.

Van Zee KJ, Barrio AV, Tchou J; Society of Surgical Oncology Breast Disease Site Work Group.

JAMA Oncol. 2016 Mar;2(3):397-8. doi: 10.1001/jamaoncol.2015.4860. No abstract available.


Satb1 Overexpression Drives Tumor-Promoting Activities in Cancer-Associated Dendritic Cells.

Tesone AJ, Rutkowski MR, Brencicova E, Svoronos N, Perales-Puchalt A, Stephen TL, Allegrezza MJ, Payne KK, Nguyen JM, Wickramasinghe J, Tchou J, Borowsky ME, Rabinovich GA, Kossenkov AV, Conejo-Garcia JR.

Cell Rep. 2016 Feb 23;14(7):1774-1786. doi: 10.1016/j.celrep.2016.01.056. Epub 2016 Feb 11.


Identification of breast cancer margins using intraoperative near-infrared imaging.

Keating J, Tchou J, Okusanya O, Fisher C, Batiste R, Jiang J, Kennedy G, Nie S, Singhal S.

J Surg Oncol. 2016 Apr;113(5):508-14. doi: 10.1002/jso.24167. Epub 2016 Feb 4.


Clinical Diagnosis and Management of Breast Cancer.

McDonald ES, Clark AS, Tchou J, Zhang P, Freedman GM.

J Nucl Med. 2016 Feb;57 Suppl 1:9S-16S. doi: 10.2967/jnumed.115.157834. Review.


Resident and Fellow Participation in Breast Surgery: An American College of Surgeons NSQIP Clinical Outcomes Analysis.

Chatterjee A, Pyfer B, Chen L, Czerniecki B, Tchou J, Fisher C.

J Am Coll Surg. 2015 Nov;221(5):988-94. doi: 10.1016/j.jamcollsurg.2015.08.008. Epub 2015 Aug 20.


Early Postoperative Outcomes in Breast Conservation Surgery Versus Simple Mastectomy with Implant Reconstruction: A NSQIP Analysis of 11,645 Patients.

Pyfer B, Chatterjee A, Chen L, Nigriny J, Czerniecki B, Tchou J, Fisher C.

Ann Surg Oncol. 2016 Jan;23(1):92-8. doi: 10.1245/s10434-015-4770-2. Epub 2015 Jul 29.


A Propensity-Matched Analysis of the Influence of Breast Reconstruction on Subsequent Development of Lymphedema.

Basta MN, Fischer JP, Kanchwala SK, Silvestre J, Wu LC, Serletti JM, Tchou JC, Kovach SJ, Fosnot J.

Plast Reconstr Surg. 2015 Aug;136(2):134e-143e. doi: 10.1097/PRS.0000000000001417.


Early postoperative outcomes in lumpectomy versus simple mastectomy.

Chatterjee A, Pyfer B, Czerniecki B, Rosenkranz K, Tchou J, Fisher C.

J Surg Res. 2015 Sep;198(1):143-8. doi: 10.1016/j.jss.2015.01.054. Epub 2015 Feb 4.


Monitoring serum HER2 levels in breast cancer patients.

Tchou J, Lam L, Li YR, Edwards C, Ky B, Zhang H.

Springerplus. 2015 May 22;4:237. doi: 10.1186/s40064-015-1015-6. eCollection 2015.


Macroscopic optical physiological parameters correlate with microscopic proliferation and vessel area breast cancer signatures.

Chung SH, Feldman MD, Martinez D, Kim H, Putt ME, Busch DR, Tchou J, Czerniecki BJ, Schnall MD, Rosen MA, DeMichele A, Yodh AG, Choe R.

Breast Cancer Res. 2015 May 27;17:72. doi: 10.1186/s13058-015-0578-z.


A Cost-Utility Analysis Comparing the Sartorius versus the Rectus Femoris Flap in the Treatment of the Infected Vascular Groin Graft Wound.

Chatterjee A, Kosowski T, Pyfer B, Fisher CS, Tchou JC, Maddali S.

Plast Reconstr Surg. 2015 Jun;135(6):1707-14. doi: 10.1097/PRS.0000000000001267. Review.


Microbially driven TLR5-dependent signaling governs distal malignant progression through tumor-promoting inflammation.

Rutkowski MR, Stephen TL, Svoronos N, Allegrezza MJ, Tesone AJ, Perales-Puchalt A, Brencicova E, Escovar-Fadul X, Nguyen JM, Cadungog MG, Zhang R, Salatino M, Tchou J, Rabinovich GA, Conejo-Garcia JR.

Cancer Cell. 2015 Jan 12;27(1):27-40. doi: 10.1016/j.ccell.2014.11.009. Epub 2014 Dec 18.


A cost-utility analysis of the use of preoperative computed tomographic angiography in abdomen-based perforator flap breast reconstruction.

Offodile AC 2nd, Chatterjee A, Vallejo S, Fisher CS, Tchou JC, Guo L.

Plast Reconstr Surg. 2015 Apr;135(4):662e-9e. doi: 10.1097/PRS.0000000000001133. Review. Erratum in: Plast Reconstr Surg. 2015 Sep;136(3):626.


Transforming growth factor β-mediated suppression of antitumor T cells requires FoxP1 transcription factor expression.

Stephen TL, Rutkowski MR, Allegrezza MJ, Perales-Puchalt A, Tesone AJ, Svoronos N, Nguyen JM, Sarmin F, Borowsky ME, Tchou J, Conejo-Garcia JR.

Immunity. 2014 Sep 18;41(3):427-439. doi: 10.1016/j.immuni.2014.08.012.


Mesothelin expression is associated with poor outcomes in breast cancer.

Li YR, Xian RR, Ziober A, Conejo-Garcia J, Perales-Puchalt A, June CH, Zhang PJ, Tchou J.

Breast Cancer Res Treat. 2014 Oct;147(3):675-84. doi: 10.1007/s10549-014-3077-5. Epub 2014 Sep 6.


Mastectomy with or without immediate implant reconstruction has similar 30-day perioperative outcomes.

Fischer JP, Wes AM, Tuggle CT, Nelson JA, Tchou JC, Serletti JM, Kovach SJ, Wu LC.

J Plast Reconstr Aesthet Surg. 2014 Nov;67(11):1515-22. doi: 10.1016/j.bjps.2014.07.021. Epub 2014 Jul 31.


Association between lymphedema self-care adherence and lymphedema outcomes among women with breast cancer-related lymphedema.

Brown JC, Kumar A, Cheville AL, Tchou JC, Troxel AB, Harris SR, Schmitz KH.

Am J Phys Med Rehabil. 2015 Apr;94(4):288-96. doi: 10.1097/PHM.0000000000000178.


Optically measured microvascular blood flow contrast of malignant breast tumors.

Choe R, Putt ME, Carlile PM, Durduran T, Giammarco JM, Busch DR, Jung KW, Czerniecki BJ, Tchou J, Feldman MD, Mies C, Rosen MA, Schnall MD, DeMichele A, Yodh AG.

PLoS One. 2014 Jun 26;9(6):e99683. doi: 10.1371/journal.pone.0099683. eCollection 2014.


Fibroblast activation protein, a potential diagnostic and therapeutic target for cancer-reply.

Tchou J, Conejo-Garcia J.

Hum Pathol. 2014 Jul;45(7):1553-4. doi: 10.1016/j.humpath.2013.11.022. Epub 2014 Mar 26. No abstract available.


Initiation of metastatic breast carcinoma by targeting of the ductal epithelium with adenovirus-cre: a novel transgenic mouse model of breast cancer.

Rutkowski MR, Allegrezza MJ, Svoronos N, Tesone AJ, Stephen TL, Perales-Puchalt A, Nguyen J, Zhang PJ, Fiering SN, Tchou J, Conejo-Garcia JR.

J Vis Exp. 2014 Mar 26;(85). doi: 10.3791/51171.


Fibroblast activation protein expression by stromal cells and tumor-associated macrophages in human breast cancer.

Tchou J, Zhang PJ, Bi Y, Satija C, Marjumdar R, Stephen TL, Lo A, Chen H, Mies C, June CH, Conejo-Garcia J, Puré E.

Hum Pathol. 2013 Nov;44(11):2549-57. doi: 10.1016/j.humpath.2013.06.016. Epub 2013 Sep 26.

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