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Items: 1 to 50 of 87

1.

Outcome and impact of post-remission strategy after MIDAM regimen in patients with relapsing or refractory acute myeloid leukemia.

Bahashwan S, Moluçon-Chabrot C, Hermet E, Ravinet A, Douge A, Veronese L, Tchirkov A, Lemal R, Berger MG, Veyrat-Masson R, Tournilhac O, Bay JO, Guièze R.

Am J Hematol. 2019 Jan;94(1):E32-E35. doi: 10.1002/ajh.25332. Epub 2018 Nov 25. No abstract available.

PMID:
30370957
2.

Very long-term molecular follow-up of minimal residual disease in patients with neuroblastoma.

Tchirkov A, Greze V, Plantaz D, Rouel N, Vago P, Kanold J.

Pediatr Blood Cancer. 2018 Dec;65(12):e27404. doi: 10.1002/pbc.27404. Epub 2018 Sep 14.

PMID:
30216652
3.

Sperm meiotic segregation of a balanced interchromosomal reciprocal insertion resulting in recurrent spontaneous miscarriage.

Salaun G, Tchirkov A, Francannet C, Pons H, Brugnon F, Pebrel-Richard C, Gouas L, Eymard-Pierre E, Vago P, Goumy C.

Reprod Biomed Online. 2018 Jul;37(1):100-106. doi: 10.1016/j.rbmo.2018.03.019. Epub 2018 Apr 9.

PMID:
29680196
4.

Event-free survival of infants and toddlers enrolled in the HR-NBL-1/SIOPEN trial is associated with the level of neuroblastoma mRNAs at diagnosis.

Corrias MV, Parodi S, Tchirkov A, Lammens T, Vicha A, Pasqualini C, Träger C, Yáñez Y, Dallorso S, Varesio L, Luksch R, Laureys G, Valteau-Couanet D, Canete A, Pöetschger U, Ladenstein R, Burchill SA.

Pediatr Blood Cancer. 2018 Jul;65(7):e27052. doi: 10.1002/pbc.27052. Epub 2018 Mar 30.

5.

TERT promoter status and gene copy number gains: effect on TERT expression and association with prognosis in breast cancer.

Gay-Bellile M, Véronèse L, Combes P, Eymard-Pierre E, Kwiatkowski F, Dauplat MM, Cayre A, Privat M, Abrial C, Bignon YJ, Mouret-Reynier MA, Vago P, Penault-Llorca F, Tchirkov A.

Oncotarget. 2017 Aug 24;8(44):77540-77551. doi: 10.18632/oncotarget.20560. eCollection 2017 Sep 29.

6.

RT-qPCR for PHOX2B mRNA is a highly specific and sensitive method to assess neuroblastoma minimal residual disease in testicular tissue.

Grèze V, Kanold J, Chambon F, Halle P, Gremeau AS, Rives N, Rouel N, Pereira B, Tchirkov A, Brugnon F.

Oncol Lett. 2017 Jul;14(1):860-866. doi: 10.3892/ol.2017.6238. Epub 2017 May 24.

7.

ERCC1 and telomere status in breast tumours treated with neoadjuvant chemotherapy and their association with patient prognosis.

Gay-Bellile M, Romero P, Cayre A, Véronèse L, Privat M, Singh S, Combes P, Kwiatkowski F, Abrial C, Bignon YJ, Vago P, Penault-Llorca F, Tchirkov A.

J Pathol Clin Res. 2016 Jul 13;2(4):234-246. eCollection 2016 Oct.

8.

Highly sensitive assessment of neuroblastoma minimal residual disease in ovarian tissue using RT-qPCR-A strategy for improving the safety of fertility restoration.

Grèze V, Brugnon F, Chambon F, Halle P, Canis M, Amiot C, Grémeau AS, Pereira B, Yáñez Peralta Y, Tchirkov A, Kanold J.

Pediatr Blood Cancer. 2017 May;64(5). doi: 10.1002/pbc.26287. Epub 2016 Oct 12.

PMID:
27734578
9.

Telomere status in chronic lymphocytic leukemia with TP53 disruption.

Guièze R, Pages M, Véronèse L, Combes P, Lemal R, Gay-Bellile M, Chauvet M, Callanan M, Kwiatkowski F, Pereira B, Vago P, Bay JO, Tournilhac O, Tchirkov A.

Oncotarget. 2016 Aug 30;7(35):56976-56985. doi: 10.18632/oncotarget.10927.

10.

A novel 2q14.1q14.3 deletion involving GLI2 and RNU4ATAC genes associated with partial corpus callosum agenesis and severe intrauterine growth retardation.

Goumy C, Gay-Bellile M, Salaun G, Kemeny S, Eymard-Pierre E, Biard M, Pebrel-Richard C, Vanlieferinghen P, Francannet C, Tchirkov A, Laurichesse H, Rouzade C, Gouas L, Vago P.

Birth Defects Res A Clin Mol Teratol. 2016 Sep;106(9):793-7. doi: 10.1002/bdra.23535. Epub 2016 Jun 27.

PMID:
27346851
11.

Different dose rate-dependent responses of human melanoma cells and fibroblasts to low dose fast neutrons.

Dionet C, Müller-Barthélémy M, Marceau G, Denis JM, Averbeck D, Gueulette J, Sapin V, Pereira B, Tchirkov A, Chautard E, Verrelle P.

Int J Radiat Biol. 2016 Sep;92(9):527-35. doi: 10.1080/09553002.2016.1186300. Epub 2016 Jun 3.

12.

Characterization by microarray and meiotic segregation study of a der(10)t(10;18) in a patient with infertility and normal phenotype.

Kemeny S, Brugnon F, Eymard-Pierre E, Goumy C, Janny L, Tchirkov A, Francannet C, Vago P, Pebrel-Richard C.

Asian J Androl. 2017 Jan-Feb;19(1):135-137. doi: 10.4103/1008-682X.172818. No abstract available.

13.

Highly efficient radiosensitization of human glioblastoma and lung cancer cells by a G-quadruplex DNA binding compound.

Merle P, Gueugneau M, Teulade-Fichou MP, Müller-Barthélémy M, Amiard S, Chautard E, Guetta C, Dedieu V, Communal Y, Mergny JL, Gallego M, White C, Verrelle P, Tchirkov A.

Sci Rep. 2015 Nov 6;5:16255. doi: 10.1038/srep16255.

14.

Prenatal Screening of 21 Microdeletion/Microduplication Syndromes and Subtelomeric Imbalances by MLPA in Fetuses with Increased Nuchal Translucency and Normal Karyotype.

Gouas L, Kémény S, Beaufrère AM, Eymard-Pierre E, Pebrel-Richard C, Tchirkov A, Lemery D, Laurichesse-Delmas H, Vago P, Goumy C.

Cytogenet Genome Res. 2015;146(1):28-32. doi: 10.1159/000435865. Epub 2015 Jul 21.

PMID:
26201711
15.

Clinical impact of the NKp30/B7-H6 axis in high-risk neuroblastoma patients.

Semeraro M, Rusakiewicz S, Minard-Colin V, Delahaye NF, Enot D, Vély F, Marabelle A, Papoular B, Piperoglou C, Ponzoni M, Perri P, Tchirkov A, Matta J, Lapierre V, Shekarian T, Valsesia-Wittmann S, Commo F, Prada N, Poirier-Colame V, Bressac B, Cotteret S, Brugieres L, Farace F, Chaput N, Kroemer G, Valteau-Couanet D, Zitvogel L.

Sci Transl Med. 2015 Apr 15;7(283):283ra55. doi: 10.1126/scitranslmed.aaa2327.

PMID:
25877893
16.

Congenital diaphragmatic hernia may be associated with 17q12 microdeletion syndrome.

Goumy C, Laffargue F, Eymard-Pierre E, Kemeny S, Gay-Bellile M, Gouas L, Gallot D, Francannet C, Tchirkov A, Pebrel-Richard C, Vago P.

Am J Med Genet A. 2015 Jan;167A(1):250-3. doi: 10.1002/ajmg.a.36840. Epub 2014 Nov 25.

PMID:
25425496
17.

Refinement of the critical region in a new 7p22.1 microduplication syndrome including craniofacial dysmorphism and speech delay.

Pebrel-Richard C, Rouzade C, Kemeny S, Eymard-Pierre E, Gay-Bellile M, Gouas L, Tchirkov A, Goumy C, Vago P.

Am J Med Genet A. 2014 Nov;164A(11):2964-7. doi: 10.1002/ajmg.a.36715. Epub 2014 Aug 14. No abstract available.

PMID:
25124455
18.

Clinical and molecular description of a 17q21.33 microduplication in a girl with severe kyphoscoliosis and developmental delay.

Kemeny S, Pebrel-Richard C, Eymard-Pierre E, Gay-Bellile M, Gouas L, Goumy C, Tchirkov A, Francannet C, Vago P.

Eur J Med Genet. 2014 Oct;57(10):552-7. doi: 10.1016/j.ejmg.2014.07.003. Epub 2014 Aug 6.

PMID:
25106685
19.

De novo 2q36.1q36.3 interstitial deletion involving the PAX3 and EPHA4 genes in a fetus with spina bifida and cleft palate.

Goumy C, Gay-Bellile M, Eymard-Pierre E, Kemeny S, Gouas L, Déchelotte P, Gallot D, Véronèse L, Tchirkov A, Pebrel-Richard C, Vago P.

Birth Defects Res A Clin Mol Teratol. 2014 Jun;100(6):507-11. doi: 10.1002/bdra.23246. Epub 2014 Apr 18.

PMID:
24753315
20.

Prevalence of aneuploidies in products of spontaneous abortion: interest of FISH and MLPA.

Haoud K, Mellali S, Gouas L, Tchirkov A, Vago P, Moulessehoul S.

Morphologie. 2014 Mar;98(320):40-6. doi: 10.1016/j.morpho.2014.02.001. Epub 2014 Mar 16.

PMID:
24646446
21.

Neuroblastoma mRNAs predict outcome in children with stage 4 neuroblastoma: a European HR-NBL1/SIOPEN study.

Viprey VF, Gregory WM, Corrias MV, Tchirkov A, Swerts K, Vicha A, Dallorso S, Brock P, Luksch R, Valteau-Couanet D, Papadakis V, Laureys G, Pearson AD, Ladenstein R, Burchill SA.

J Clin Oncol. 2014 Apr 1;32(10):1074-83. doi: 10.1200/JCO.2013.53.3604. Epub 2014 Mar 3.

PMID:
24590653
22.

Early telomere shortening and genomic instability in tubo-ovarian preneoplastic lesions--response.

Chene G, Tchirkov A, Penault-Llorca F.

Clin Cancer Res. 2013 Sep 15;19(18):5255. doi: 10.1158/1078-0432.CCR-13-1915. Epub 2013 Sep 5. No abstract available.

23.

An unusual clinical severity of 16p11.2 deletion syndrome caused by unmasked recessive mutation of CLN3.

Pebrel-Richard C, Debost-Legrand A, Eymard-Pierre E, Greze V, Kemeny S, Gay-Bellile M, Gouas L, Tchirkov A, Vago P, Goumy C, Francannet C.

Eur J Hum Genet. 2014 Mar;22(3):369-73. doi: 10.1038/ejhg.2013.141. Epub 2013 Jul 17.

24.

Molecular assessment of minimal residual disease in PBSC harvests provides prognostic information in neuroblastoma.

Chambon F, Tchirkov A, Pereira B, Rochette E, Deméocq F, Kanold J.

Pediatr Blood Cancer. 2013 Sep;60(9):E109-12. doi: 10.1002/pbc.24538. Epub 2013 Mar 21.

PMID:
23596146
25.

Early telomere shortening and genomic instability in tubo-ovarian preneoplastic lesions.

Chene G, Tchirkov A, Pierre-Eymard E, Dauplat J, Raoelfils I, Cayre A, Watkin E, Vago P, Penault-Llorca F.

Clin Cancer Res. 2013 Jun 1;19(11):2873-82. doi: 10.1158/1078-0432.CCR-12-3947. Epub 2013 Apr 15.

26.

Prenatal ultrasound diagnosis of a 48,XXYY syndrome.

Kemeny S, Pebrel-Richard C, Gouas L, Veronese L, Lemery D, Tchirkov A, Goumy C, Vago P.

Morphologie. 2013 Jun;97(317):65-7. doi: 10.1016/j.morpho.2013.01.001. Epub 2013 Mar 7.

PMID:
23473874
27.

Contribution of MLPA to routine diagnostic testing of recurrent genomic aberrations in chronic lymphocytic leukemia.

Véronèse L, Tournilhac O, Combes P, Prie N, Pierre-Eymard E, Guièze R, Veyrat-Masson R, Bay JO, Vago P, Tchirkov A.

Cancer Genet. 2013 Jan-Feb;206(1-2):19-25. doi: 10.1016/j.cancergen.2012.12.002. Epub 2013 Jan 10.

PMID:
23313109
28.

A new case of 8q22.1 microdeletion restricts the critical region for Nablus mask-like facial syndrome.

Debost-Legrand A, Eymard-Pierre E, Pebrel-Richard C, Gouas L, Goumy C, Giollant M, Ayed W, Tchirkov A, Francannet C, Vago P.

Am J Med Genet A. 2013 Jan;161A(1):162-5. doi: 10.1002/ajmg.a.35614. Epub 2012 Dec 13.

PMID:
23239647
29.

[Trisomy 21 and cancers].

Ayed W, Gouas L, Penault-Llorca F, Amouri A, Tchirkov A, Vago P.

Morphologie. 2012 Oct;96(314-315):57-66. doi: 10.1016/j.morpho.2012.10.001. Epub 2012 Nov 7. Review. French.

PMID:
23141635
30.

Telomeres and chromosomal instability in chronic lymphocytic leukemia.

Véronèse L, Tournilhac O, Callanan M, Prie N, Kwiatkowski F, Combes P, Chauvet M, Davi F, Gouas L, Verrelle P, Guièze R, Vago P, Bay JO, Tchirkov A.

Leukemia. 2013 Feb;27(2):490-3. doi: 10.1038/leu.2012.194. Epub 2012 Jul 13. No abstract available.

PMID:
22878603
31.

An atypical 0.8 Mb inherited duplication of 22q11.2 associated with psychomotor impairment.

Pebrel-Richard C, Kemeny S, Gouas L, Eymard-Pierre E, Blanc N, Francannet C, Tchirkov A, Goumy C, Vago P.

Eur J Med Genet. 2012 Nov;55(11):650-5. doi: 10.1016/j.ejmg.2012.06.014. Epub 2012 Jul 14.

PMID:
22796526
32.

NK cytotoxicity and alloreactivity against neuroblastoma cell lines in vitro: comparison of Europium fluorometry assay and quantification by RT-PCR.

Paillard C, Halle P, Tchirkov A, Confland C, Veyrat-Masson R, Quainon F, Perreira B, Rochette E, Pfeiffer M, Lang P, Deméocq F, Kanold J.

J Immunol Methods. 2012 Jun 29;380(1-2):56-64. doi: 10.1016/j.jim.2012.03.009. Epub 2012 Apr 10.

PMID:
22516232
33.

NK cell immunotherapy for high-risk neuroblastoma relapse after haploidentical HSCT.

Kanold J, Paillard C, Tchirkov A, Lang P, Kelly A, Halle P, Isfan F, Merlin E, Marabelle A, Rochette E, Deméocq F.

Pediatr Blood Cancer. 2012 Oct;59(4):739-42. doi: 10.1002/pbc.24030. Epub 2011 Dec 16.

PMID:
22180305
34.

Prenatal diagnosis of a rare de novo centromeric chromosome 6 variant.

Goumy C, Kemeny S, Eymard-Pierre E, Richard C, Gouas L, Combes P, Gay-Bellile M, Gallot D, Tchirkov A, Vago P.

Gene. 2011 Dec 15;490(1-2):15-7. doi: 10.1016/j.gene.2011.09.008. Epub 2011 Oct 1.

PMID:
21989483
35.

Telomere targeting with a new G4 ligand enhances radiation-induced killing of human glioblastoma cells.

Merle P, Evrard B, Petitjean A, Lehn JM, Teulade-Fichou MP, Chautard E, De Cian A, Guittat L, Tran PL, Mergny JL, Verrelle P, Tchirkov A.

Mol Cancer Ther. 2011 Oct;10(10):1784-95. doi: 10.1158/1535-7163.MCT-10-0664.

36.

De novo unbalanced translocation 2;4 characterized by metaphase CGH and array CGH in a child with mental retardation and dysmorphic features.

Debost-Legrand A, Capri Y, Gouas L, Pebrel-Richard C, Veronese L, Tchirkov A, Haoud K, Boespflug-Tanguy O, Goumy C, Vago P.

Pathol Biol (Paris). 2011 Dec;59(6):309-13. doi: 10.1016/j.patbio.2010.11.004. Epub 2010 Dec 9.

PMID:
21145667
37.

CD34+ immunoselection of autologous grafts for the treatment of high-risk neuroblastoma.

Marabelle A, Merlin E, Halle P, Paillard C, Berger M, Tchirkov A, Rousseau R, Leverger G, Piguet C, Stephan JL, Demeocq F, Kanold J.

Pediatr Blood Cancer. 2011 Jan;56(1):134-42. doi: 10.1002/pbc.22840.

PMID:
21058288
38.

Increased expression of the oncogenic KLF6-SV1 transcript in human glioblastoma.

Tchirkov A, Sapin V, Marceau G, Chautard E, Narla G, Veronese L, Friedman S, Khalil T, Vago P, Kemeny JL, Verrelle P.

Clin Chem Lab Med. 2010 Aug;48(8):1167-70. doi: 10.1515/CCLM.2010.219.

PMID:
20545576
39.

Retinoid pathway and congenital diaphragmatic hernia: hypothesis from the analysis of chromosomal abnormalities.

Goumy C, Gouas L, Marceau G, Coste K, Veronese L, Gallot D, Sapin V, Vago P, Tchirkov A.

Fetal Diagn Ther. 2010;28(3):129-39. doi: 10.1159/000313331. Epub 2010 May 26. Review.

40.

Prenatal detection of cryptic rearrangements by multiplex ligation probe amplification in fetuses with ultrasound abnormalities.

Goumy C, Gouas L, Pebrel-Richard C, Véronèse L, Eymard-Pierre E, Debost-Legrand A, Haoud K, Tchirkov A, Vago P.

Genet Med. 2010 Jun;12(6):376-80. doi: 10.1097/GIM.0b013e3181e074c6.

PMID:
20453657
41.

Akt signaling pathway: a target for radiosensitizing human malignant glioma.

Chautard E, Loubeau G, Tchirkov A, Chassagne J, Vermot-Desroches C, Morel L, Verrelle P.

Neuro Oncol. 2010 May;12(5):434-43. doi: 10.1093/neuonc/nop059. Epub 2010 Feb 4.

42.

Intraoperative imprint cytology examination of sentinel lymph nodes after neoadjuvant chemotherapy in breast cancer patients.

Gimbergues P, Dauplat MM, Durando X, Abrial C, Le Bouedec G, Mouret-Reynier MA, Cachin F, Kwiatkowski F, Tchirkov A, Dauplat J, Penault-Llorca F.

Ann Surg Oncol. 2010 Aug;17(8):2132-7. doi: 10.1245/s10434-010-0952-0. Epub 2010 Feb 13.

PMID:
20155400
43.

Fetal skin fibroblasts: a cell model for studying the retinoid pathway in congenital diaphragmatic hernia.

Goumy C, Coste K, Marceau G, Gouas L, Tchirkov A, Vago P, Gallot D, Sapin V.

Birth Defects Res A Clin Mol Teratol. 2010 Mar;88(3):195-200. doi: 10.1002/bdra.20647.

PMID:
20063272
44.

Clinical-grade production of human mesenchymal stromal cells: occurrence of aneuploidy without transformation.

Tarte K, Gaillard J, Lataillade JJ, Fouillard L, Becker M, Mossafa H, Tchirkov A, Rouard H, Henry C, Splingard M, Dulong J, Monnier D, Gourmelon P, Gorin NC, Sensebé L; Société Française de Greffe de Moelle et Thérapie Cellulaire.

Blood. 2010 Feb 25;115(8):1549-53. doi: 10.1182/blood-2009-05-219907. Epub 2009 Dec 23.

45.

A thrombocytosis occurring in Philadelphia positive CML in molecular response to imatinib can reveal an underlying JAK2(V617F) myeloproliferative neoplasm.

Véronèse L, Tchirkov A, Richard-Pebrel C, Ledoux-Pilon A, Fleury J, Chaleteix C, Goumy C, Gouas L, Berger MG, Vago P, Bay JO, Tournilhac O.

Leuk Res. 2010 Apr;34(4):e94-6. doi: 10.1016/j.leukres.2009.09.025. Epub 2009 Oct 14. No abstract available.

PMID:
19833389
46.

Detection of twelve nucleotides insertion in the BCR-ABL kinase domain in an imatinib-resistant but dasatinib-sensitive patient with bi-phenotypic acute leukemia.

Hayette S, Chabane K, Tchirkov A, Berger MG, Nicolini FE, Tournilhac O.

Haematologica. 2009 Sep;94(9):1324-6. doi: 10.3324/haematol.2009.007864. No abstract available.

47.

Strong correlation between VEGF and MCL-1 mRNA expression levels in B-cell chronic lymphocytic leukemia.

Véronèse L, Tournilhac O, Verrelle P, Davi F, Dighiero G, Chautard E, Veyrat-Masson R, Kwiatkowski F, Goumy C, Gouas L, Bay JO, Vago P, Tchirkov A.

Leuk Res. 2009 Dec;33(12):1623-6. doi: 10.1016/j.leukres.2009.05.003. Epub 2009 May 31.

PMID:
19487028
48.

Clinicopathological factors and nomograms predicting nonsentinel lymph node metastases after neoadjuvant chemotherapy in breast cancer patients.

Gimbergues P, Abrial C, Durando X, Le Bouedec G, Cachin F, Penault-Llorca F, Mouret-Reynier MA, Kwiatkowski F, Maublant J, Tchirkov A, Dauplat J.

Ann Surg Oncol. 2009 Jul;16(7):1946-51. doi: 10.1245/s10434-009-0400-1. Epub 2009 May 2.

PMID:
19408057
49.

Allogeneic or haploidentical HSCT for refractory or relapsed solid tumors in children: toward a neuroblastoma model.

Kanold J, Paillard C, Tchirkov A, Merlin E, Marabelle A, Lutz P, Rousseau R, Baldomero H, Deméocq F.

Bone Marrow Transplant. 2008 Oct;42 Suppl 2:S25-30. doi: 10.1038/bmt.2008.279. Review.

PMID:
18978740
50.

Familial deletion 11q14.3-q22.1 without apparent phenotypic consequences: a haplosufficient 8.5 Mb region.

Goumy C, Gouas L, Tchirkov A, Roucaute T, Giollant M, Veronèse L, Francannet C, Vago P.

Am J Med Genet A. 2008 Oct 15;146A(20):2668-72. doi: 10.1002/ajmg.a.32511.

PMID:
18798310

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