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Diffusion-Weighted MR Imaging in a Prospective Cohort of Children with Cerebral Malaria Offers Insights into Pathophysiology and Prognosis.

Moghaddam SM, Birbeck GL, Taylor TE, Seydel KB, Kampondeni SD, Potchen MJ.

AJNR Am J Neuroradiol. 2019 Sep;40(9):1575-1580. doi: 10.3174/ajnr.A6159. Epub 2019 Aug 22.


Comparison of CD8+ T Cell Accumulation in the Brain During Human and Murine Cerebral Malaria.

Barrera V, Haley MJ, Strangward P, Attree E, Kamiza S, Seydel KB, Taylor TE, Milner DA Jr, Craig AG, Couper KN.

Front Immunol. 2019 Jul 24;10:1747. doi: 10.3389/fimmu.2019.01747. eCollection 2019.


Impact of Multiplicity of Plasmodium falciparum Infection on Clinical Disease in Malawi.

Earland D, Buchwald AG, Sixpence A, Chimenya M, Damson M, Seydel KB, Mathanga DP, Taylor TE, Laufer MK.

Am J Trop Med Hyg. 2019 Aug;101(2):412-415. doi: 10.4269/ajtmh.19-0093.


Binding Heterogeneity of Plasmodium falciparum to Engineered 3D Brain Microvessels Is Mediated by EPCR and ICAM-1.

Bernabeu M, Gunnarsson C, Vishnyakova M, Howard CC, Nagao RJ, Avril M, Taylor TE, Seydel KB, Zheng Y, Smith JD.

MBio. 2019 May 28;10(3). pii: e00420-19. doi: 10.1128/mBio.00420-19.


Meta-analysis of Plasmodium falciparum var Signatures Contributing to Severe Malaria in African Children and Indian Adults.

Duffy F, Bernabeu M, Babar PH, Kessler A, Wang CW, Vaz M, Chery L, Mandala WL, Rogerson SJ, Taylor TE, Seydel KB, Lavstsen T, Gomes E, Kim K, Lusingu J, Rathod PK, Aitchison JD, Smith JD.

MBio. 2019 Apr 30;10(2). pii: e00217-19. doi: 10.1128/mBio.00217-19.


Barriers and Facilitators to Obtaining Informed Consent in a Critical Care Pediatric Research Ward in Southern Malawi.

Manda-Taylor L, Liomba A, Taylor TE, Elwell K.

J Empir Res Hum Res Ethics. 2019 Apr;14(2):152-168. doi: 10.1177/1556264619830859.


Neurodevelopmental Impairments 1 Year After Cerebral Malaria.

Langfitt JT, McDermott MP, Brim R, Mboma S, Potchen MJ, Kampondeni SD, Seydel KB, Semrud-Clikeman M, Taylor TE.

Pediatrics. 2019 Feb;143(2). pii: e20181026. doi: 10.1542/peds.2018-1026. Epub 2019 Jan 29.


Cerebral malaria is associated with differential cytoadherence to brain endothelial cells.

Storm J, Jespersen JS, Seydel KB, Szestak T, Mbewe M, Chisala NV, Phula P, Wang CW, Taylor TE, Moxon CA, Lavstsen T, Craig AG.

EMBO Mol Med. 2019 Feb;11(2). pii: e9164. doi: 10.15252/emmm.201809164.


Challenges in Treatment for Fever among School-Age Children and Adults in Malawi.

Coalson JE, Cohee LM, Walldorf JA, Bauleni A, Mathanga DP, Taylor TE, Wilson ML, Laufer MK.

Am J Trop Med Hyg. 2019 Feb;100(2):287-295. doi: 10.4269/ajtmh.18-0687.


Association Between Age and Plasmodium falciparum Infection Dynamics.

Buchwald AG, Sorkin JD, Sixpence A, Chimenya M, Damson M, Wilson ML, Seydel K, Hochman S, Mathanga D, Taylor TE, Laufer MK.

Am J Epidemiol. 2019 Jan 1;188(1):169-176. doi: 10.1093/aje/kwy213.


Clinical Implications of Asymptomatic Plasmodium falciparum Infections in Malawi.

Buchwald AG, Sixpence A, Chimenya M, Damson M, Sorkin JD, Wilson ML, Seydel K, Hochman S, Mathanga DP, Taylor TE, Laufer MK.

Clin Infect Dis. 2019 Jan 1;68(1):106-112. doi: 10.1093/cid/ciy427.


Admission EEG findings in diverse paediatric cerebral malaria populations predict outcomes.

Postels DG, Wu X, Li C, Kaplan PW, Seydel KB, Taylor TE, Kousa YA, Idro R, Opoka R, John CC, Birbeck GL.

Malar J. 2018 May 22;17(1):208. doi: 10.1186/s12936-018-2355-9.


Simulation models predict that school-age children are responsible for most human-to-mosquito Plasmodium falciparum transmission in southern Malawi.

Coalson JE, Cohee LM, Buchwald AG, Nyambalo A, Kubale J, Seydel KB, Mathanga D, Taylor TE, Laufer MK, Wilson ML.

Malar J. 2018 Apr 3;17(1):147. doi: 10.1186/s12936-018-2295-4.


Neurovascular sequestration in paediatric P. falciparum malaria is visible clinically in the retina.

Barrera V, MacCormick IJC, Czanner G, Hiscott PS, White VA, Craig AG, Beare NAV, Culshaw LH, Zheng Y, Biddolph SC, Milner DA, Kamiza S, Molyneux ME, Taylor TE, Harding SP.

Elife. 2018 Mar 26;7. pii: e32208. doi: 10.7554/eLife.32208.


Noninvasive measures of brain edema predict outcome in pediatric cerebral malaria.

Kampondeni SD, Birbeck GL, Seydel KB, Beare NA, Glover SJ, Hammond CA, Chilingulo CA, Taylor TE, Potchen MJ.

Surg Neurol Int. 2018 Mar 1;9:53. doi: 10.4103/sni.sni_297_17. eCollection 2018.


A targeted approach for routine viral load monitoring in Malawian adults on antiretroviral therapy.

Mungwira RG, Divala TH, Nyirenda OM, Kanjala M, Muwalo F, Mkandawire FA, Choko A, Taylor TE, Mallewa J, van Oosterhout JJ, Laufer MK, Laurens MB.

Trop Med Int Health. 2018 May;23(5):526-532. doi: 10.1111/tmi.13047. Epub 2018 Mar 30.


Pathology-Based Research in Africa.

Lemos MP, Taylor TE, McGoldrick SM, Molyneux ME, Menon M, Kussick S, Mkhize NN, Martinson NA, Stritmatter A, Randolph-Habecker J.

Clin Lab Med. 2018 Mar;38(1):67-90. doi: 10.1016/j.cll.2017.10.006. Review.


Objective Assessment of Patient Inhaler User Technique Using an Audio-Based Classification Approach.

Taylor TE, Zigel Y, Egan C, Hughes F, Costello RW, Reilly RB.

Sci Rep. 2018 Feb 1;8(1):2164. doi: 10.1038/s41598-018-20523-w.


Estimation of inhalation flow profile using audio-based methods to assess inhaler medication adherence.

Taylor TE, Lacalle Muls H, Costello RW, Reilly RB.

PLoS One. 2018 Jan 18;13(1):e0191330. doi: 10.1371/journal.pone.0191330. eCollection 2018.


1.5 Tesla Magnetic Resonance Imaging to Investigate Potential Etiologies of Brain Swelling in Pediatric Cerebral Malaria.

Potchen MJ, Kampondeni SD, Seydel KB, Haacke EM, Sinyangwe SS, Mwenechanya M, Glover SJ, Milner DA, Zeli E, Hammond CA, Utriainen D, Lishimpi K, Taylor TE, Birbeck GL.

Am J Trop Med Hyg. 2018 Feb;98(2):497-504. doi: 10.4269/ajtmh.17-0309. Epub 2018 Jan 4.


Linking EPCR-Binding PfEMP1 to Brain Swelling in Pediatric Cerebral Malaria.

Kessler A, Dankwa S, Bernabeu M, Harawa V, Danziger SA, Duffy F, Kampondeni SD, Potchen MJ, Dambrauskas N, Vigdorovich V, Oliver BG, Hochman SE, Mowrey WB, MacCormick IJC, Mandala WL, Rogerson SJ, Sather DN, Aitchison JD, Taylor TE, Seydel KB, Smith JD, Kim K.

Cell Host Microbe. 2017 Nov 8;22(5):601-614.e5. doi: 10.1016/j.chom.2017.09.009. Epub 2017 Oct 26.


Advances in Audio-Based Systems to Monitor Patient Adherence and Inhaler Drug Delivery.

Taylor TE, Zigel Y, De Looze C, Sulaiman I, Costello RW, Reilly RB.

Chest. 2018 Mar;153(3):710-722. doi: 10.1016/j.chest.2017.08.1162. Epub 2017 Sep 5. Review.


Magnetic Resonance Imaging of Cerebral Malaria Patients Reveals Distinct Pathogenetic Processes in Different Parts of the Brain.

Mohanty S, Benjamin LA, Majhi M, Panda P, Kampondeni S, Sahu PK, Mohanty A, Mahanta KC, Pattnaik R, Mohanty RR, Joshi S, Mohanty A, Turnbull IW, Dondorp AM, Taylor TE, Wassmer SC.

mSphere. 2017 Jun 7;2(3). pii: e00193-17. doi: 10.1128/mSphere.00193-17. eCollection 2017 May-Jun.


Evidence from a natural experiment that malaria parasitemia is pathogenic in retinopathy-negative cerebral malaria.

Small DS, Taylor TE, Postels DG, Beare NA, Cheng J, MacCormick IJ, Seydel KB.

Elife. 2017 Jun 7;6. pii: e23699. doi: 10.7554/eLife.23699.


Frequent malaria illness episodes in two Malawian patients on antiretroviral therapy soon after stopping cotrimoxazole preventive therapy.

Nyangulu WJ, Mwinjiwa E, Divala TH, Mungwira RG, Nyirenda O, Kanjala M, Mbambo G, Mallewa J, Taylor TE, Laurens MB, Laufer MK, van Oosterhout JJ.

Malawi Med J. 2017 Mar;29(1):57-60.


Measuring Success in Global Health Training: Data From 14 Years of a Postdoctoral Fellowship in Infectious Diseases and Tropical Medicine.

Tucker JD, Hughes MA, Durvasula RV, Vinetz JM, McGovern VP, Schultz R, Dunavan CP, Wilson ME, Milner DA, LaRocque RC, Calderwood SB, Guerrant RL, Weller PF, Taylor TE.

Clin Infect Dis. 2017 Jun 15;64(12):1768-1772. doi: 10.1093/cid/cix242.


Changes in inhaler inhalation acoustic features during induced bronchoconstriction: a pilot study.

McCartan TA, Taylor TE, Sulaiman I, Costello RW, Reilly RB.

Conf Proc IEEE Eng Med Biol Soc. 2016 Aug;2016:3749-3752. doi: 10.1109/EMBC.2016.7591543.


Automated Detection of Malarial Retinopathy in Digital Fundus Images for Improved Diagnosis in Malawian Children with Clinically Defined Cerebral Malaria.

Joshi V, Agurto C, Barriga S, Nemeth S, Soliz P, MacCormick IJ, Lewallen S, Taylor TE, Harding SP.

Sci Rep. 2017 Feb 15;7:42703. doi: 10.1038/srep42703.


Insecticide-treated net effectiveness at preventing Plasmodium falciparum infection varies by age and season.

Buchwald AG, Coalson JE, Cohee LM, Walldorf JA, Chimbiya N, Bauleni A, Nkanaunena K, Ngwira A, Sorkin JD, Mathanga DP, Taylor TE, Laufer MK.

Malar J. 2017 Jan 17;16(1):32. doi: 10.1186/s12936-017-1686-2.


Patterns and determinants of malaria risk in urban and peri-urban areas of Blantyre, Malawi.

Mathanga DP, Tembo AK, Mzilahowa T, Bauleni A, Mtimaukenena K, Taylor TE, Valim C, Walker ED, Wilson ML.

Malar J. 2016 Dec 8;15(1):590.


Decreased Rate of Plasma Arginine Appearance in Murine Malaria May Explain Hypoargininemia in Children With Cerebral Malaria.

Alkaitis MS, Wang H, Ikeda AK, Rowley CA, MacCormick IJ, Chertow JH, Billker O, Suffredini AF, Roberts DJ, Taylor TE, Seydel KB, Ackerman HC.

J Infect Dis. 2016 Dec 15;214(12):1840-1849.


High prevalence of Plasmodium falciparum gametocyte infections in school-age children using molecular detection: patterns and predictors of risk from a cross-sectional study in southern Malawi.

Coalson JE, Walldorf JA, Cohee LM, Ismail MD, Mathanga D, Cordy RJ, Marti M, Taylor TE, Seydel KB, Laufer MK, Wilson ML.

Malar J. 2016 Nov 4;15(1):527.


Safety of lumbar puncture in comatose children with clinical features of cerebral malaria.

Moxon CA, Zhao L, Li C, Seydel KB, MacCormick IJ, Diggle PJ, Mallewa M, Solomon T, Beare NA, Glover SJ, Harding SP, Lewallen S, Kampondeni S, Potchen MJ, Taylor TE, Postels DG.

Neurology. 2016 Nov 29;87(22):2355-2362. Epub 2016 Oct 28.


Parasite dynamics in the peripheral blood and the placenta during pregnancy-associated malaria infection.

Cohee LM, Kalilani-Phiri L, Mawindo P, Joshi S, Adams M, Kenefic L, Jacob CG, Taylor TE, Laufer MK.

Malar J. 2016 Sep 21;15(1):483.


TSCQ study: a randomized, controlled, open-label trial of daily trimethoprim-sulfamethoxazole or weekly chloroquine among adults on antiretroviral therapy in Malawi: study protocol for a randomized controlled trial.

Laurens MB, Mungwira RG, Nyirenda OM, Divala TH, Kanjala M, Muwalo F, Mkandawire FA, Tsirizani L, Nyangulu W, Mwinjiwa E, Taylor TE, Mallewa J, Blackwelder WC, Plowe CV, Laufer MK, van Oosterhout JJ.

Trials. 2016 Jul 18;17(1):322. doi: 10.1186/s13063-016-1392-3.


Predicting asthma exacerbations employing remotely monitored adherence.

Killane I, Sulaiman I, MacHale E, Breathnach A, Taylor TE, Holmes MS, Reilly RB, Costello RW.

Healthc Technol Lett. 2016 Mar 23;3(1):51-5. doi: 10.1049/htl.2015.0058. eCollection 2016 Mar.


Bed net use among school-aged children after a universal bed net campaign in Malawi.

Buchwald AG, Walldorf JA, Cohee LM, Coalson JE, Chimbiya N, Bauleni A, Nkanaunena K, Ngwira A, Kapito-Tembo A, Mathanga DP, Taylor TE, Laufer MK.

Malar J. 2016 Feb 29;15:127. doi: 10.1186/s12936-016-1178-9.


Evidence for spleen dysfunction in malaria-HIV co-infection in a subset of pediatric patients.

Joice R, Frantzreb C, Pradham A, Seydel KB, Kamiza S, Wirth DF, Duraisingh MT, Molyneux ME, Taylor TE, Marti M, Milner DA Jr.

Mod Pathol. 2016 Apr;29(4):381-90. doi: 10.1038/modpathol.2016.27. Epub 2016 Feb 26.


Monitoring Inhaler Inhalations Using an Acoustic Sensor Proximal to Inhaler Devices.

Taylor TE, Holmes MS, Sulaiman I, Costello RW, Reilly RB.

J Aerosol Med Pulm Drug Deliv. 2016 Oct;29(5):439-446. Epub 2016 Feb 9.


Author Correction for Hochman et al., Fatal Pediatric Cerebral Malaria Is Associated with Intravascular Monocytes and Platelets That Are Increased with HIV Coinfection.

Hochman SE, Madaline TF, Wassmer SC, Mbale E, Choi N, Seydel KB, Whitten RO, Varughese J, Grau GE, Kamiza S, Molyneux ME, Taylor TE, Lee S, Milner DA Jr, Kim K.

MBio. 2016 Feb 2;7(1):e02068-15. doi: 10.1128/mBio.02068-15. No abstract available.


Intramuscular Artesunate for Severe Malaria in African Children: A Multicenter Randomized Controlled Trial.

Kremsner PG, Adegnika AA, Hounkpatin AB, Zinsou JF, Taylor TE, Chimalizeni Y, Liomba A, Kombila M, Bouyou-Akotet MK, Mawili Mboumba DP, Agbenyega T, Ansong D, Sylverken J, Ogutu BR, Otieno GA, Wangwe A, Bojang KA, Okomo U, Sanya-Isijola F, Newton CR, Njuguna P, Kazungu M, Kerb R, Geditz M, Schwab M, Velavan TP, Nguetse C, Köhler C, Issifou S, Bolte S, Engleitner T, Mordmüller B, Krishna S.

PLoS Med. 2016 Jan 12;13(1):e1001938. doi: 10.1371/journal.pmed.1001938. eCollection 2016 Jan.


Influences of gender and anthropometric features on inspiratory inhaler acoustics and peak inspiratory flow rate.

Taylor TE, Holmes MS, Sulaiman I, Costello RW, Reilly RB.

Conf Proc IEEE Eng Med Biol Soc. 2015;2015:2227-30. doi: 10.1109/EMBC.2015.7318834.


Lymphocyte Perturbations in Malawian Children with Severe and Uncomplicated Malaria.

Mandala WL, Msefula CL, Gondwe EN, Gilchrist JJ, Graham SM, Pensulo P, Mwimaniwa G, Banda M, Taylor TE, Molyneux EE, Drayson MT, Ward SA, Molyneux ME, MacLennan CA.

Clin Vaccine Immunol. 2015 Nov 18;23(2):95-103. doi: 10.1128/CVI.00564-15.


The prevalence of malaria at first antenatal visit in Blantyre, Malawi declined following a universal bed net campaign.

Boudová S, Divala T, Mawindo P, Cohee L, Kalilani-Phiri L, Thesing P, Taylor TE, Laufer MK.

Malar J. 2015 Oct 29;14:422. doi: 10.1186/s12936-015-0945-3.


The effect of local variation in malaria transmission on the prevalence of sulfadoxine-pyrimethamine resistant haplotypes and selective sweep characteristics in Malawi.

Artimovich E, Kapito-Tembo A, Pensulo P, Nyirenda O, Brown S, Joshi S, Taylor TE, Mathanga D, Escalante AA, Laufer MK, Takala-Harrison S.

Malar J. 2015 Oct 5;14:387. doi: 10.1186/s12936-015-0860-7.


Fatal Pediatric Cerebral Malaria Is Associated with Intravascular Monocytes and Platelets That Are Increased with HIV Coinfection.

Hochman SE, Madaline TF, Wassmer SC, Mbale E, Choi N, Seydel KB, Whitten RO, Varughese J, Grau GE, Kamiza S, Molyneux ME, Taylor TE, Lee S, Milner DA Jr, Kim K.

MBio. 2015 Sep 22;6(5):e01390-15. doi: 10.1128/mBio.01390-15. Erratum in: MBio. 2016;7(1):e02068-15.


Investigating the Pathogenesis of Severe Malaria: A Multidisciplinary and Cross-Geographical Approach.

Wassmer SC, Taylor TE, Rathod PK, Mishra SK, Mohanty S, Arevalo-Herrera M, Duraisingh MT, Smith JD.

Am J Trop Med Hyg. 2015 Sep;93(3 Suppl):42-56. doi: 10.4269/ajtmh.14-0841. Epub 2015 Aug 10. Review.


School-Age Children Are a Reservoir of Malaria Infection in Malawi.

Walldorf JA, Cohee LM, Coalson JE, Bauleni A, Nkanaunena K, Kapito-Tembo A, Seydel KB, Ali D, Mathanga D, Taylor TE, Valim C, Laufer MK.

PLoS One. 2015 Jul 24;10(7):e0134061. doi: 10.1371/journal.pone.0134061. eCollection 2015.


Laboratory evidence of disseminated intravascular coagulation is associated with a fatal outcome in children with cerebral malaria despite an absence of clinically evident thrombosis or bleeding.

Moxon CA, Chisala NV, Mzikamanda R, MacCormick I, Harding S, Downey C, Molyneux M, Seydel KB, Taylor TE, Heyderman RS, Toh CH.

J Thromb Haemost. 2015 Sep;13(9):1653-64. doi: 10.1111/jth.13060. Epub 2015 Aug 27. Erratum in: J Thromb Haemost. 2016 Feb;14(2):415.


Modeling malaria genomics reveals transmission decline and rebound in Senegal.

Daniels RF, Schaffner SF, Wenger EA, Proctor JL, Chang HH, Wong W, Baro N, Ndiaye D, Fall FB, Ndiop M, Ba M, Milner DA Jr, Taylor TE, Neafsey DE, Volkman SK, Eckhoff PA, Hartl DL, Wirth DF.

Proc Natl Acad Sci U S A. 2015 Jun 2;112(22):7067-72. doi: 10.1073/pnas.1505691112. Epub 2015 May 4.

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