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An overview of statistical methods for handling non-adherence to intervention protocol in randomised control trials (RCTs): A methodological review.

Mostazir M, Taylor RS, Henley W, Watkins E.

J Clin Epidemiol. 2018 Dec 7. pii: S0895-4356(18)30494-3. doi: 10.1016/j.jclinepi.2018.12.002. [Epub ahead of print] Review.


Does a Screening Trial for Spinal Cord Stimulation in Patients with Chronic Pain of Neuropathic Origin have Clinical Utility and Cost-Effectiveness? (TRIAL-STIM Study): study protocol for a randomised controlled trial.

Eldabe S, Gulve A, Thomson S, Baranidharan G, Duarte R, Jowett S, Sandhu H, Chadwick R, Brookes M, Tariq A, Earle J, Bell J, Kansal A, Rhodes S, Taylor RS.

Trials. 2018 Nov 16;19(1):633. doi: 10.1186/s13063-018-2993-9.


The effects and costs of home-based rehabilitation for heart failure with reduced ejection fraction: The REACH-HF multicentre randomized controlled trial.

Dalal HM, Taylor RS, Jolly K, Davis RC, Doherty P, Miles J, van Lingen R, Warren FC, Green C, Wingham J, Greaves C, Sadler S, Hillsdon M, Abraham C, Britten N, Frost J, Singh S, Hayward C, Eyre V, Paul K, Lang CC, Smith K.

Eur J Prev Cardiol. 2018 Oct 10:2047487318806358. doi: 10.1177/2047487318806358. [Epub ahead of print]


Impact of exercise-based cardiac rehabilitation in patients with heart failure (ExTraMATCH II) on mortality and hospitalisation: an individual patient data meta-analysis of randomised trials.

Taylor RS, Walker S, Smart NA, Piepoli MF, Warren FC, Ciani O, O'Connor C, Whellan D, Keteyian SJ, Coats A, Davos CH, Dalal HM, Dracup K, Evangelista L, Jolly K, Myers J, McKelvie RS, Nilsson BB, Passino C, Witham MD, Yeh GY, Zwisler AO; ExTraMATCH II Collaboration.

Eur J Heart Fail. 2018 Sep 26. doi: 10.1002/ejhf.1311. [Epub ahead of print]


Multicentred randomised controlled trial of an augmented exercise referral scheme using web-based behavioural support in individuals with metabolic, musculoskeletal and mental health conditions: protocol for the e-coachER trial.

Ingram W, Webb D, Taylor RS, Anokye N, Yardley L, Jolly K, Mutrie N, Campbell JL, Dean SG, Greaves C, Steele M, Lambert JD, McAdam C, Jane B, King J, Jones RB, Little P, Woolf A, Erwin J, Charles N, Terry RH, Taylor AH; Trial Steering Committee.

BMJ Open. 2018 Sep 21;8(9):e022382. doi: 10.1136/bmjopen-2018-022382.


Singing for people with aphasia (SPA): a protocol for a pilot randomised controlled trial of a group singing intervention to improve well-being.

Tarrant M, Carter M, Dean SG, Taylor RS, Warren FC, Spencer A, Adamson J, Landa P, Code C, Calitri R.

BMJ Open. 2018 Sep 10;8(9):e025167. doi: 10.1136/bmjopen-2018-025167.


Waptia fieldensis Walcott, a mandibulate arthropod from the middle Cambrian Burgess Shale.

Vannier J, Aria C, Taylor RS, Caron JB.

R Soc Open Sci. 2018 Jun 20;5(6):172206. doi: 10.1098/rsos.172206. eCollection 2018 Jun.


Validation of Exercise Capacity as a Surrogate Endpoint in Exercise-Based Rehabilitation for Heart Failure: A Meta-Analysis of Randomized Controlled Trials.

Ciani O, Piepoli M, Smart N, Uddin J, Walker S, Warren FC, Zwisler AD, Davos CH, Taylor RS.

JACC Heart Fail. 2018 Jul;6(7):596-604. doi: 10.1016/j.jchf.2018.03.017.


Enhanced psychological care in cardiac rehabilitation services for patients with new-onset depression: the CADENCE feasibility study and pilot RCT.

Richards SH, Campbell JL, Dickens C, Anderson R, Gandhi M, Gibson A, Kessler D, Knight L, Kuyken W, Richards DA, Taylor RS, Turner K, Ukoumunne OC, Davey A, Warren FC, Winder RE, Wright CA.

Health Technol Assess. 2018 May;22(30):1-220. doi: 10.3310/hta22300.


Physical activity, sleep, and fatigue in community dwelling Stroke Survivors.

Shepherd AI, Pulsford R, Poltawski L, Forster A, Taylor RS, Spencer A, Hollands L, James M, Allison R, Norris M, Calitri R, Dean SG.

Sci Rep. 2018 May 21;8(1):7900. doi: 10.1038/s41598-018-26279-7.


A Randomized Controlled Trial of Subcutaneous Nerve Stimulation for Back Pain Due to Failed Back Surgery Syndrome: The SubQStim Study.

Eldabe SS, Taylor RS, Goossens S, Bouche B, Gültuna I, Green C, Tinsley J, Luyet PP, Buchser E.

Neuromodulation. 2018 Apr 28. doi: 10.1111/ner.12784. [Epub ahead of print]


Impact of cardiac rehabilitation on cardiac mortality.

Taylor RS, Dalal H.

Eur Heart J Qual Care Clin Outcomes. 2018 Jul 1;4(3):148-149. doi: 10.1093/ehjqcco/qcy017. No abstract available.


Decision uncertainty and value of further research: a case-study in fenestrated endovascular aneurysm repair for complex abdominal aortic aneurysms.

Ciani O, Epstein D, Rothery C, Taylor RS, Sculpher M.

Cost Eff Resour Alloc. 2018 Apr 16;16:15. doi: 10.1186/s12962-018-0098-7. eCollection 2018.


Cardiac rehabilitation and physical activity: systematic review and meta-analysis.

Dibben GO, Dalal HM, Taylor RS, Doherty P, Tang LH, Hillsdon M.

Heart. 2018 Sep;104(17):1394-1402. doi: 10.1136/heartjnl-2017-312832. Epub 2018 Apr 13. Review.


A randomised controlled trial of a facilitated home-based rehabilitation intervention in patients with heart failure with preserved ejection fraction and their caregivers: the REACH-HFpEF Pilot Study.

Lang CC, Smith K, Wingham J, Eyre V, Greaves CJ, Warren FC, Green C, Jolly K, Davis RC, Doherty PJ, Miles J, Britten N, Abraham C, Van Lingen R, Singh SJ, Paul K, Hillsdon M, Sadler S, Hayward C, Dalal HM, Taylor RS; REACH-HF investigators,.

BMJ Open. 2018 Apr 9;8(4):e019649. doi: 10.1136/bmjopen-2017-019649.


Assessing the effectiveness of Enhanced Psychological Care for patients with depressive symptoms attending cardiac rehabilitation compared with treatment as usual (CADENCE): a pilot cluster randomised controlled trial.

Richards SH, Dickens C, Anderson R, Richards DA, Taylor RS, Ukoumunne OC, Turner KM, Gandhi M, Kuyken W, Gibson A, Davey A, Warren F, Winder R, Campbell J.

Trials. 2018 Apr 2;19(1):211. doi: 10.1186/s13063-018-2576-9.


Short- and long-term cost and utilization of health care resources in Parkinson's disease in the UK.

Weir S, Samnaliev M, Kuo TC, Tierney TS, Walleser Autiero S, Taylor RS, Schrag A.

Mov Disord. 2018 Jul;33(6):974-981. doi: 10.1002/mds.27302. Epub 2018 Mar 30.


Comparison of treatment effect sizes from pivotal and postapproval trials of novel therapeutics approved by the FDA based on surrogate markers of disease: a meta-epidemiological study.

Wallach JD, Ciani O, Pease AM, Gonsalves GS, Krumholz HM, Taylor RS, Ross JS.

BMC Med. 2018 Mar 21;16(1):45. doi: 10.1186/s12916-018-1023-9.


The Surgical Approach to the Anterior Nucleus of Thalamus in Patients With Refractory Epilepsy: Experience from the International Multicenter Registry (MORE).

Lehtimäki K, Coenen VA, Gonçalves Ferreira A, Boon P, Elger C, Taylor RS, Ryvlin P, Gil-Nagel A, Gielen F, Brionne TC, Abouihia A, Beth G; MORE investigators.

Neurosurgery. 2018 Mar 15. doi: 10.1093/neuros/nyy023. [Epub ahead of print]


Community-based rehabilitation training after stroke: results of a pilot randomised controlled trial (ReTrain) investigating acceptability and feasibility.

Dean SG, Poltawski L, Forster A, Taylor RS, Spencer A, James M, Allison R, Stevens S, Norris M, Shepherd AI, Landa P, Pulsford RM, Hollands L, Calitri R.

BMJ Open. 2018 Feb 15;8(2):e018409. doi: 10.1136/bmjopen-2017-018409.


Exercise-based cardiac rehabilitation for adults with stable angina.

Long L, Anderson L, Dewhirst AM, He J, Bridges C, Gandhi M, Taylor RS.

Cochrane Database Syst Rev. 2018 Feb 2;2:CD012786. doi: 10.1002/14651858.CD012786.pub2. Review.


Feasibility study to assess the impact of a lifestyle intervention ('LivingWELL') in people having an assessment of their family history of colorectal or breast cancer.

Anderson AS, Dunlop J, Gallant S, Macleod M, Miedzybrodzka Z, Mutrie N, O'Carroll RE, Stead M, Steele RJC, Taylor RS, Vinnicombe S, Berg J.

BMJ Open. 2018 Feb 1;8(2):e019410. doi: 10.1136/bmjopen-2017-019410.


Cluster randomised controlled trial and economic and process evaluation to determine the effectiveness and cost-effectiveness of a novel intervention [Healthy Lifestyles Programme (HeLP)] to prevent obesity in school children.

Wyatt K, Lloyd J, Creanor S, Green C, Dean SG, Hillsdon M, Abraham C, Tomlinson R, Pearson V, Taylor RS, Ryan E, Streeter A, McHugh C, Hurst A, Price L, Crathorne L, Krägeloh C, Siegert R, Logan S.

Southampton (UK): NIHR Journals Library; 2018 Jan.


Effectiveness of the Healthy Lifestyles Programme (HeLP) to prevent obesity in UK primary-school children: a cluster randomised controlled trial.

Lloyd J, Creanor S, Logan S, Green C, Dean SG, Hillsdon M, Abraham C, Tomlinson R, Pearson V, Taylor RS, Ryan E, Price L, Streeter A, Wyatt K.

Lancet Child Adolesc Health. 2018 Jan;2(1):35-45. doi: 10.1016/S2352-4642(17)30151-7.


Facet-joint injections for non-specific low back pain: a feasibility RCT.

Snidvongs S, Taylor RS, Ahmad A, Thomson S, Sharma M, Farr A, Fitzsimmons D, Poulton S, Mehta V, Langford R.

Health Technol Assess. 2017 Dec;21(74):1-130. doi: 10.3310/hta21740.


Psychological interventions for coronary heart disease: Cochrane systematic review and meta-analysis.

Richards SH, Anderson L, Jenkinson CE, Whalley B, Rees K, Davies P, Bennett P, Liu Z, West R, Thompson DR, Taylor RS.

Eur J Prev Cardiol. 2018 Feb;25(3):247-259. doi: 10.1177/2047487317739978. Epub 2017 Dec 7.


Five year trends (2008-2012) in cardiac implantable electrical device utilization in five European nations: a case study in cross-country comparisons using administrative databases.

Banks H, Torbica A, Valzania C, Varabyova Y, Prevolnik Rupel V, Taylor RS, Hunger T, Walker S, Boriani G, Fattore G; MedtecHTA group.

Europace. 2018 Apr 1;20(4):643-653. doi: 10.1093/europace/eux123.


The incidence and healthcare costs of persistent postoperative pain following lumbar spine surgery in the UK: a cohort study using the Clinical Practice Research Datalink (CPRD) and Hospital Episode Statistics (HES).

Weir S, Samnaliev M, Kuo TC, Ni Choitir C, Tierney TS, Cumming D, Bruce J, Manca A, Taylor RS, Eldabe S.

BMJ Open. 2017 Sep 11;7(9):e017585. doi: 10.1136/bmjopen-2017-017585.


Cost and Outcome of BehaviouRal Activation (COBRA): a randomised controlled trial of behavioural activation versus cognitive-behavioural therapy for depression.

Richards DA, Rhodes S, Ekers D, McMillan D, Taylor RS, Byford S, Barrett B, Finning K, Ganguli P, Warren F, Farrand P, Gilbody S, Kuyken W, O'Mahen H, Watkins E, Wright K, Reed N, Fletcher E, Hollon SD, Moore L, Backhouse A, Farrow C, Garry J, Kemp D, Plummer F, Warner F, Woodhouse R.

Health Technol Assess. 2017 Aug;21(46):1-366. doi: 10.3310/hta21460.


Comparison of a structured home-based rehabilitation programme with conventional supervised pulmonary rehabilitation: a randomised non-inferiority trial.

Horton EJ, Mitchell KE, Johnson-Warrington V, Apps LD, Sewell L, Morgan M, Taylor RS, Singh SJ.

Thorax. 2018 Jan;73(1):29-36. doi: 10.1136/thoraxjnl-2016-208506. Epub 2017 Jul 29.


A directly comparative two-gate case-control diagnostic accuracy study of the pure tone screen and HearCheck screener tests for identifying hearing impairment in school children.

Ukoumunne OC, Hyde C, Ozolins M, Zhelev Z, Errington S, Taylor RS, Benton C, Moody J, Cocking L, Watson J, Fortnum H.

BMJ Open. 2017 Jul 11;7(7):e017258. doi: 10.1136/bmjopen-2017-017258.


Pilot randomised controlled trial of the ENGAGER collaborative care intervention for prisoners with common mental health problems, near to and after release.

Lennox C, Kirkpatrick T, Taylor RS, Todd R, Greenwood C, Haddad M, Stevenson C, Stewart A, Shenton D, Carroll L, Brand SL, Quinn C, Anderson R, Maguire M, Harris T, Shaw J, Byng R.

Pilot Feasibility Stud. 2017 Jul 7;4:15. doi: 10.1186/s40814-017-0163-6. eCollection 2018. Erratum in: Pilot Feasibility Stud. 2017 Oct 24;3:48.


Associations between interarm differences in blood pressure and cardiovascular disease outcomes: protocol for an individual patient data meta-analysis and development of a prognostic algorithm.

Clark CE, Boddy K, Warren FC, Taylor RS, Aboyans V, Cloutier L, McManus RJ, Shore AC, Campbell JL.

BMJ Open. 2017 Jul 2;7(6):e016844. doi: 10.1136/bmjopen-2017-016844.


Home-based versus centre-based cardiac rehabilitation.

Anderson L, Sharp GA, Norton RJ, Dalal H, Dean SG, Jolly K, Cowie A, Zawada A, Taylor RS.

Cochrane Database Syst Rev. 2017 Jun 30;6:CD007130. doi: 10.1002/14651858.CD007130.pub4. Review.


Patient education in the management of coronary heart disease.

Anderson L, Brown JP, Clark AM, Dalal H, Rossau HK, Bridges C, Taylor RS.

Cochrane Database Syst Rev. 2017 Jun 28;6:CD008895. doi: 10.1002/14651858.CD008895.pub3. Review.


Debt Counselling for Depression in Primary Care: an adaptive randomised controlled pilot trial (DeCoDer study).

Gabbay MB, Ring A, Byng R, Anderson P, Taylor RS, Matthews C, Harris T, Berry V, Byrne P, Carter E, Clarke P, Cocking L, Edwards S, Emsley R, Fornasiero M, Frith L, Harris S, Huxley P, Jones S, Kinderman P, King M, Kosnes L, Marshall D, Mercer D, May C, Nolan D, Phillips C, Rawcliffe T, Sardani AV, Shaw E, Thompson S, Vickery J, Wainman B, Warner M.

Health Technol Assess. 2017 Jun;21(35):1-164. doi: 10.3310/hta21350.


Psychological interventions for coronary heart disease.

Richards SH, Anderson L, Jenkinson CE, Whalley B, Rees K, Davies P, Bennett P, Liu Z, West R, Thompson DR, Taylor RS.

Cochrane Database Syst Rev. 2017 Apr 28;4:CD002902. doi: 10.1002/14651858.CD002902.pub4. Review.


Trial baseline characteristics of a cluster randomised controlled trial of a school-located obesity prevention programme; the Healthy Lifestyles Programme (HeLP) trial.

Lloyd J, Creanor S, Price L, Abraham C, Dean S, Green C, Hillsdon M, Pearson V, Taylor RS, Tomlinson R, Logan S, Hurst A, Ryan E, Daurge W, Wyatt K.

BMC Public Health. 2017 Apr 4;17(1):291. doi: 10.1186/s12889-017-4196-9.


Exercise-based cardiac rehabilitation in heart transplant recipients.

Anderson L, Nguyen TT, Dall CH, Burgess L, Bridges C, Taylor RS.

Cochrane Database Syst Rev. 2017 Apr 4;4:CD012264. doi: 10.1002/14651858.CD012264.pub2. Review.


Time to Review the Role of Surrogate End Points in Health Policy: State of the Art and the Way Forward.

Ciani O, Buyse M, Drummond M, Rasi G, Saad ED, Taylor RS.

Value Health. 2017 Mar;20(3):487-495. doi: 10.1016/j.jval.2016.10.011. Epub 2016 Dec 22. Review.


The patient education - Learning and Coping Strategies - improves adherence in cardiac rehabilitation (LC-REHAB): A randomised controlled trial.

Lynggaard V, Nielsen CV, Zwisler AD, Taylor RS, May O.

Int J Cardiol. 2017 Jun 1;236:65-70. doi: 10.1016/j.ijcard.2017.02.051. Epub 2017 Feb 21.


The Efficacy of Exercise-Based Cardiac Rehabilitation: The Changing Face of Usual Care.

Taylor RS, Anderson L, Oldridge N, Thompson DR, Zwisler AD, Dalal H.

J Am Coll Cardiol. 2017 Mar 7;69(9):1207-1208. doi: 10.1016/j.jacc.2016.10.084. No abstract available.


Exercise-based cardiac rehabilitation for adults with atrial fibrillation.

Risom SS, Zwisler AD, Johansen PP, Sibilitz KL, Lindschou J, Gluud C, Taylor RS, Svendsen JH, Berg SK.

Cochrane Database Syst Rev. 2017 Feb 9;2:CD011197. doi: 10.1002/14651858.CD011197.pub2. Review.


Patients' preference for exercise setting and its influence on the health benefits gained from exercise-based cardiac rehabilitation.

Tang LH, Kikkenborg Berg S, Christensen J, Lawaetz J, Doherty P, Taylor RS, Langberg H, Zwisler AD.

Int J Cardiol. 2017 Apr 1;232:33-39. doi: 10.1016/j.ijcard.2017.01.126. Epub 2017 Jan 27.


A bias-adjusted evidence synthesis of RCT and observational data: the case of total hip replacement.

Schnell-Inderst P, Iglesias CP, Arvandi M, Ciani O, Matteucci Gothe R, Peters J, Blom AW, Taylor RS, Siebert U.

Health Econ. 2017 Feb;26 Suppl 1:46-69. doi: 10.1002/hec.3474. Review.


Linking the Regulatory and Reimbursement Processes for Medical Devices: The Need for Integrated Assessments.

Ciani O, Wilcher B, van Giessen A, Taylor RS.

Health Econ. 2017 Feb;26 Suppl 1:13-29. doi: 10.1002/hec.3479. Review.


Behavioural activation training for depression - Authors' reply.

Richards DA, Finning K, Taylor RS.

Lancet. 2017 Jan 28;389(10067):367-368. doi: 10.1016/S0140-6736(17)30160-5. No abstract available.



Larsen RT, Christensen J, Tang LH, Keller C, Doherty P, Zwisler AD, Taylor RS, Langberg H.

Int J Sports Phys Ther. 2016 Dec;11(7):1006-1039.


Detailed statistical analysis plan for a cluster randomised controlled trial of the Healthy Lifestyles Programme (HeLP), a novel school-based intervention to prevent obesity in school children.

Creanor S, Lloyd J, Hillsdon M, Dean S, Green C, Taylor RS, Ryan E, Wyatt K; HeLP Trial Management Group.

Trials. 2016 Dec 15;17(1):599.

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