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Items: 1 to 50 of 76

1.

ALK2 inhibitors display beneficial effects in preclinical models of ACVR1 mutant diffuse intrinsic pontine glioma.

Carvalho D, Taylor KR, Olaciregui NG, Molinari V, Clarke M, Mackay A, Ruddle R, Henley A, Valenti M, Hayes A, Brandon AH, Eccles SA, Raynaud F, Boudhar A, Monje M, Popov S, Moore AS, Mora J, Cruz O, Vinci M, Brennan PE, Bullock AN, Carcaboso AM, Jones C.

Commun Biol. 2019 May 9;2(1):156. doi: 10.1038/s42003-019-0420-8.

PMID:
31925004
2.

What is your diagnosis? Maxillary sinus mass in a young Lowline Angus bull.

Wong JK, Eren MV, Hanna AL, Bredenberg AR, Taylor KR.

Vet Clin Pathol. 2019 Nov 3. doi: 10.1111/vcp.12794. [Epub ahead of print] No abstract available.

PMID:
31680277
3.

Electrical and synaptic integration of glioma into neural circuits.

Venkatesh HS, Morishita W, Geraghty AC, Silverbush D, Gillespie SM, Arzt M, Tam LT, Espenel C, Ponnuswami A, Ni L, Woo PJ, Taylor KR, Agarwal A, Regev A, Brang D, Vogel H, Hervey-Jumper S, Bergles DE, Suvà ML, Malenka RC, Monje M.

Nature. 2019 Sep;573(7775):539-545. doi: 10.1038/s41586-019-1563-y. Epub 2019 Sep 18.

PMID:
31534222
4.

Schwannosis in Three Foals and a Calf.

Miranda IC, Taylor KR, Castleman W, de Lahunta A, Summers BA, Miller AD.

Vet Pathol. 2019 Sep;56(5):783-788. doi: 10.1177/0300985819846872. Epub 2019 May 20.

PMID:
31109258
5.

ALK2 inhibitors display beneficial effects in preclinical models of ACVR1 mutant diffuse intrinsic pontine glioma.

Carvalho D, Taylor KR, Olaciregui NG, Molinari V, Clarke M, Mackay A, Ruddle R, Henley A, Valenti M, Hayes A, Brandon AH, Eccles SA, Raynaud F, Boudhar A, Monje M, Popov S, Moore AS, Mora J, Cruz O, Vinci M, Brennan PE, Bullock AN, Carcaboso AM, Jones C.

Commun Biol. 2019 May 9;2:156. doi: 10.1038/s42003-019-0420-8. eCollection 2019.

6.

Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cells.

Vinci M, Burford A, Molinari V, Kessler K, Popov S, Clarke M, Taylor KR, Pemberton HN, Lord CJ, Gutteridge A, Forshew T, Carvalho D, Marshall LV, Qin EY, Ingram WJ, Moore AS, Ng HK, Trabelsi S, H'mida-Ben Brahim D, Entz-Werle N, Zacharoulis S, Vaidya S, Mandeville HC, Bridges LR, Martin AJ, Al-Sarraj S, Chandler C, Sunol M, Mora J, de Torres C, Cruz O, Carcaboso AM, Monje M, Mackay A, Jones C.

Nat Med. 2018 Aug;24(8):1204-1215. doi: 10.1038/s41591-018-0086-7. Epub 2018 Jul 2.

7.

Ahr and Cyp1a2 genotypes both affect susceptibility to motor deficits following gestational and lactational exposure to polychlorinated biphenyls.

Colter BT, Garber HF, Fleming SM, Fowler JP, Harding GD, Hooven MK, Howes AA, Infante SK, Lang AL, MacDougall MC, Stegman M, Taylor KR, Curran CP.

Neurotoxicology. 2018 Mar;65:125-134. doi: 10.1016/j.neuro.2018.01.008.

8.

A relapsing fever group Borrelia sp. is widely distributed among wild deer in Japan.

Kumagai Y, Sato K, Taylor KR, Zamoto-Niikura A, Imaoka K, Morikawa S, Ohnishi M, Kawabata H.

Ticks Tick Borne Dis. 2018 Mar;9(3):465-470. doi: 10.1016/j.ttbdis.2017.12.016. Epub 2017 Dec 28.

PMID:
29329785
9.

IGF1R signalling in testicular germ cell tumour cells impacts on cell survival and acquired cisplatin resistance.

Selfe J, Goddard NC, McIntyre A, Taylor KR, Renshaw J, Popov SD, Thway K, Summersgill B, Huddart RA, Gilbert DC, Shipley JM.

J Pathol. 2018 Feb;244(2):242-253. doi: 10.1002/path.5008. Epub 2018 Jan 10.

10.

Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma.

Mackay A, Burford A, Carvalho D, Izquierdo E, Fazal-Salom J, Taylor KR, Bjerke L, Clarke M, Vinci M, Nandhabalan M, Temelso S, Popov S, Molinari V, Raman P, Waanders AJ, Han HJ, Gupta S, Marshall L, Zacharoulis S, Vaidya S, Mandeville HC, Bridges LR, Martin AJ, Al-Sarraj S, Chandler C, Ng HK, Li X, Mu K, Trabelsi S, Brahim DH, Kisljakov AN, Konovalov DM, Moore AS, Carcaboso AM, Sunol M, de Torres C, Cruz O, Mora J, Shats LI, Stavale JN, Bidinotto LT, Reis RM, Entz-Werle N, Farrell M, Cryan J, Crimmins D, Caird J, Pears J, Monje M, Debily MA, Castel D, Grill J, Hawkins C, Nikbakht H, Jabado N, Baker SJ, Pfister SM, Jones DTW, Fouladi M, von Bueren AO, Baudis M, Resnick A, Jones C.

Cancer Cell. 2017 Oct 9;32(4):520-537.e5. doi: 10.1016/j.ccell.2017.08.017. Epub 2017 Sep 28.

11.

First molecular detection and characterization of Hepatozoon and Sarcocystis spp. in field mice and voles from Japan.

Moustafa MAM, Shimozuru M, Mohamed W, Taylor KR, Nakao R, Sashika M, Tsubota T.

Parasitol Res. 2017 Aug;116(8):2321-2325. doi: 10.1007/s00436-017-5505-z. Epub 2017 May 19.

PMID:
28526989
12.

Transcriptional Dependencies in Diffuse Intrinsic Pontine Glioma.

Nagaraja S, Vitanza NA, Woo PJ, Taylor KR, Liu F, Zhang L, Li M, Meng W, Ponnuswami A, Sun W, Ma J, Hulleman E, Swigut T, Wysocka J, Tang Y, Monje M.

Cancer Cell. 2017 May 8;31(5):635-652.e6. doi: 10.1016/j.ccell.2017.03.011. Epub 2017 Apr 20.

13.

Suspected myelodysplastic/myeloproliferative neoplasm in a feline leukemia virus-negative cat.

Weeden AL, Taylor KR, Terrell SP, Gallagher AE, Wamsley HL.

Vet Clin Pathol. 2016 Dec;45(4):584-593. doi: 10.1111/vcp.12426. Epub 2016 Nov 21.

PMID:
27870069
14.

Immunomodulatory therapy with anti-interleukin-1 after photorefractive keratectomy in the New Zealand white rabbit.

Taylor KR, Panday VA, Caldwell MC, Petroll WM, Apsey DA, Reilly CD.

J Cataract Refract Surg. 2016 Jun;42(6):913-9. doi: 10.1016/j.jcrs.2016.02.050.

PMID:
27373399
15.

Four Cases of Spontaneous Neoplasia in the Naked Mole-Rat (Heterocephalus glaber), A Putative Cancer-Resistant Species.

Taylor KR, Milone NA, Rodriguez CE.

J Gerontol A Biol Sci Med Sci. 2017 Jan;72(1):38-43. Epub 2016 Apr 29.

PMID:
27129918
16.

Oesophageal rupture masquerading as STEMI.

Skaug B, Taylor KR, Chandrasekaran S.

BMJ Case Rep. 2016 Apr 11;2016:10.1136/bcr-2016-214906. doi: 10.1136/bcr-2016-214906.

17.

Spinal Cord Hamartomatous Myelodysplasia in 2 Horses With Clinical Neurologic Deficits.

Taylor KR, MacKay RJ, Nelson EA, Stieler AL, Roberts JF, Castleman WL.

Vet Pathol. 2016 Jul;53(4):844-6. doi: 10.1177/0300985815622971. Epub 2016 Feb 25.

PMID:
26917551
18.

Surgical management of an odontogenic tumor in a banded Gila monster (Heloderma suspectum cinctum) with a novel herpesvirus.

Goe AM, Heard DJ, Abbott JR, de Mello Souza CH, Taylor KR, Sthay JN, Wellehan JF.

Vet Q. 2016 Jun;36(2):109-14. doi: 10.1080/01652176.2016.1153169. Epub 2016 Mar 4. No abstract available.

PMID:
26863112
19.

Visual outcomes after femtosecond laser in situ keratomileusis flap complications.

Jadav DS, Desai N, Taylor KR, Caldwell MC, Panday VA, Reilly CD.

J Cataract Refract Surg. 2015 Nov;41(11):2487-92. doi: 10.1016/j.jcrs.2015.05.024.

PMID:
26703500
20.

Audioprofile Surfaces: The 21st Century Audiogram.

Taylor KR, Booth KT, Azaiez H, Sloan CM, Kolbe DL, Glanz EN, Shearer AE, DeLuca AP, Anand VN, Hildebrand MS, Simpson AC, Eppsteiner RW, Scheetz TE, Braun TA, Huygen PL, Smith RJ, Casavant TL.

Ann Otol Rhinol Laryngol. 2016 May;125(5):361-8. doi: 10.1177/0003489415614863. Epub 2015 Nov 3.

21.

Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes.

Castel D, Philippe C, Calmon R, Le Dret L, Truffaux N, Boddaert N, Pagès M, Taylor KR, Saulnier P, Lacroix L, Mackay A, Jones C, Sainte-Rose C, Blauwblomme T, Andreiuolo F, Puget S, Grill J, Varlet P, Debily MA.

Acta Neuropathol. 2015 Dec;130(6):815-27. doi: 10.1007/s00401-015-1478-0. Epub 2015 Sep 23.

22.

Retrospective Analysis Comparing the Preoperative and Postoperative "Q" Values for 2 Different Lasers in Refractive Surgery.

Molchan RP, Taylor KR, Panday VA, Caldwell MC, Reilly CD.

Cornea. 2015 Nov;34(11):1437-40. doi: 10.1097/ICO.0000000000000611.

PMID:
26356749
23.

Multiple-locus variable-number tandem repeat analysis of Leptospira interrogans and Leptospira borgpetersenii isolated from small feral and wild mammals in East Asia.

Koizumi N, Izumiya H, Mu JJ, Arent Z, Okano S, Nakajima C, Suzuki Y, Mizutani Muto M, Tanikawa T, Taylor KR, Komatsu N, Yoshimatsu K, Thi Thu Ha H, Ohnishi M.

Infect Genet Evol. 2015 Dec;36:434-440. doi: 10.1016/j.meegid.2015.08.013. Epub 2015 Aug 18.

24.

Chordomas at High Prevalence in the Captive Population of the Endangered Perdido Key Beach Mouse (Peromyscus polionotus trissyllepsis).

Taylor KR, Garner MM, Russell K, Epperson ED, Grodi HA, Roff SR, Dumonceaux GA, Struthers JD, Dark MJ, Abbott JR.

Vet Pathol. 2016 Jan;53(1):163-9. doi: 10.1177/0300985815575051. Epub 2015 Mar 19.

PMID:
25791038
25.

Obesity impairs γδ T cell homeostasis and antiviral function in humans.

Costanzo AE, Taylor KR, Dutt S, Han PP, Fujioka K, Jameson JM.

PLoS One. 2015 Mar 18;10(3):e0120918. doi: 10.1371/journal.pone.0120918. eCollection 2015.

26.

The effect of silicone hydrogel bandage soft contact lens base curvature on comfort and outcomes after photorefractive keratectomy.

Taylor KR, Molchan RP, Townley JR, Caldwell MC, Panday VA.

Eye Contact Lens. 2015 Mar;41(2):77-83. doi: 10.1097/ICL.0000000000000067.

PMID:
25230081
27.

Comparison of 3 silicone hydrogel bandage soft contact lenses for pain control after photorefractive keratectomy.

Taylor KR, Caldwell MC, Payne AM, Apsey DA, Townley JR, Reilly CD, Panday VA.

J Cataract Refract Surg. 2014 Nov;40(11):1798-804. doi: 10.1016/j.jcrs.2014.02.040. Epub 2014 Sep 10.

PMID:
25217073
28.

ACVR1 mutations in DIPG: lessons learned from FOP.

Taylor KR, Vinci M, Bullock AN, Jones C.

Cancer Res. 2014 Sep 1;74(17):4565-70. doi: 10.1158/0008-5472.CAN-14-1298. Epub 2014 Aug 18. Review.

29.

Cordova: web-based management of genetic variation data.

Ephraim SS, Anand N, DeLuca AP, Taylor KR, Kolbe DL, Simpson AC, Azaiez H, Sloan CM, Shearer AE, Hallier AR, Casavant TL, Scheetz TE, Smith RJ, Braun TA.

Bioinformatics. 2014 Dec 1;30(23):3438-9. doi: 10.1093/bioinformatics/btu539. Epub 2014 Aug 14.

30.

Pregabalin versus placebo in postoperative pain relief of patients' status post photorefractive keratectomy: a double-masked, randomized, prospective study.

Meek JM, Rosbolt MB, Taylor KR, Fusco EA, Panday VA, Reilly CD.

J Ocul Pharmacol Ther. 2014 Sep;30(7):527-32. doi: 10.1089/jop.2013.0208. Epub 2014 Jun 10.

PMID:
24914779
31.

Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations.

Buczkowicz P, Hoeman C, Rakopoulos P, Pajovic S, Letourneau L, Dzamba M, Morrison A, Lewis P, Bouffet E, Bartels U, Zuccaro J, Agnihotri S, Ryall S, Barszczyk M, Chornenkyy Y, Bourgey M, Bourque G, Montpetit A, Cordero F, Castelo-Branco P, Mangerel J, Tabori U, Ho KC, Huang A, Taylor KR, Mackay A, Bendel AE, Nazarian J, Fangusaro JR, Karajannis MA, Zagzag D, Foreman NK, Donson A, Hegert JV, Smith A, Chan J, Lafay-Cousin L, Dunn S, Hukin J, Dunham C, Scheinemann K, Michaud J, Zelcer S, Ramsay D, Cain J, Brennan C, Souweidane MM, Jones C, Allis CD, Brudno M, Becher O, Hawkins C.

Nat Genet. 2014 May;46(5):451-6. doi: 10.1038/ng.2936. Epub 2014 Apr 6.

32.

Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma.

Taylor KR, Mackay A, Truffaux N, Butterfield Y, Morozova O, Philippe C, Castel D, Grasso CS, Vinci M, Carvalho D, Carcaboso AM, de Torres C, Cruz O, Mora J, Entz-Werle N, Ingram WJ, Monje M, Hargrave D, Bullock AN, Puget S, Yip S, Jones C, Grill J.

Nat Genet. 2014 May;46(5):457-461. doi: 10.1038/ng.2925. Epub 2014 Apr 6.

33.

Novel approach for the treatment of corneal ectasia in a graft.

Dang TQ, Molchan RP, Taylor KR, Reilly CD, Panday VA, Caldwell MC.

Cornea. 2014 Mar;33(3):310-2. doi: 10.1097/ICO.0000000000000052.

PMID:
24452217
34.

A convenient method to produce [(14) C]carbon monoxide and its application to the radiosynthesis of [carboxyl-(14) C]celivarone, [carboxyl-(14) C]SSR149744.

Whitehead DM, Hartmann S, Ilyas T, Taylor KR, Kohler AD, Ellames GJ.

J Labelled Comp Radiopharm. 2013 Feb;56(2):36-41. doi: 10.1002/jlcr.3009. Epub 2013 Jan 22.

PMID:
24285280
35.

Dual blockade of the PI3K/AKT/mTOR (AZD8055) and RAS/MEK/ERK (AZD6244) pathways synergistically inhibits rhabdomyosarcoma cell growth in vitro and in vivo.

Renshaw J, Taylor KR, Bishop R, Valenti M, De Haven Brandon A, Gowan S, Eccles SA, Ruddle RR, Johnson LD, Raynaud FI, Selfe JL, Thway K, Pietsch T, Pearson AD, Shipley J.

Clin Cancer Res. 2013 Nov 1;19(21):5940-51. doi: 10.1158/1078-0432.CCR-13-0850. Epub 2013 Aug 5.

36.

Advancing genetic testing for deafness with genomic technology.

Shearer AE, Black-Ziegelbein EA, Hildebrand MS, Eppsteiner RW, Ravi H, Joshi S, Guiffre AC, Sloan CM, Happe S, Howard SD, Novak B, Deluca AP, Taylor KR, Scheetz TE, Braun TA, Casavant TL, Kimberling WJ, Leproust EM, Smith RJ.

J Med Genet. 2013 Sep;50(9):627-34. doi: 10.1136/jmedgenet-2013-101749. Epub 2013 Jun 26.

37.

Histone H3.3. mutations drive pediatric glioblastoma through upregulation of MYCN.

Bjerke L, Mackay A, Nandhabalan M, Burford A, Jury A, Popov S, Bax DA, Carvalho D, Taylor KR, Vinci M, Bajrami I, McGonnell IM, Lord CJ, Reis RM, Hargrave D, Ashworth A, Workman P, Jones C.

Cancer Discov. 2013 May;3(5):512-9.

38.

Prioritization of retinal disease genes: an integrative approach.

Wagner AH, Taylor KR, DeLuca AP, Casavant TL, Mullins RF, Stone EM, Scheetz TE, Braun TA.

Hum Mutat. 2013 Jun;34(6):853-9. doi: 10.1002/humu.22317. Epub 2013 Apr 12.

39.

Differential tick burdens may explain differential Borrelia afzelii and Borrelia garinii infection rates among four, wild, rodent species in Hokkaido, Japan.

Taylor KR, Takano A, Konnai S, Shimozuru M, Kawabata H, Tsubota T.

J Vet Med Sci. 2013;75(6):785-90. Epub 2013 Feb 8.

40.

AudioGene: predicting hearing loss genotypes from phenotypes to guide genetic screening.

Taylor KR, Deluca AP, Shearer AE, Hildebrand MS, Black-Ziegelbein EA, Anand VN, Sloan CM, Eppsteiner RW, Scheetz TE, Huygen PL, Smith RJ, Braun TA, Casavant TL.

Hum Mutat. 2013 Apr;34(4):539-45. doi: 10.1002/humu.22268. Epub 2013 Feb 19.

41.

Borrelia miyamotoi infections among wild rodents show age and month independence and correlation with Ixodes persulcatus larval attachment in Hokkaido, Japan.

Taylor KR, Takano A, Konnai S, Shimozuru M, Kawabata H, Tsubota T.

Vector Borne Zoonotic Dis. 2013 Feb;13(2):92-7. doi: 10.1089/vbz.2012.1027. Epub 2012 Dec 4.

42.

A novel relapsing fever Borrelia sp. infects the salivary glands of the molted hard tick, Amblyomma geoemydae.

Takano A, Sugimori C, Fujita H, Kadosaka T, Taylor KR, Tsubota T, Konnai S, Tajima T, Sato K, Watanabe H, Ohnishi M, Kawabata H.

Ticks Tick Borne Dis. 2012 Sep;3(4):259-61. doi: 10.1016/j.ttbdis.2012.06.003. Epub 2012 Jul 27.

PMID:
22910061
43.

Using the phenome and genome to improve genetic diagnosis for deafness.

Eppsteiner RW, Shearer AE, Hildebrand MS, Taylor KR, Deluca AP, Scherer S, Huygen P, Scheetz TE, Braun TA, Casavant TL, Smith RJ.

Otolaryngol Head Neck Surg. 2012 Nov;147(5):975-7. doi: 10.1177/0194599812454271. Epub 2012 Jul 11. No abstract available.

44.

Immunomodulation at epithelial sites by obesity and metabolic disease.

Cheung KP, Taylor KR, Jameson JM.

Immunol Res. 2012 Jun;52(3):182-99. doi: 10.1007/s12026-011-8261-7. Review.

PMID:
22160809
45.

Antitumor activity of sustained N-myc reduction in rhabdomyosarcomas and transcriptional block by antigene therapy.

Tonelli R, McIntyre A, Camerin C, Walters ZS, Di Leo K, Selfe J, Purgato S, Missiaglia E, Tortori A, Renshaw J, Astolfi A, Taylor KR, Serravalle S, Bishop R, Nanni C, Valentijn LJ, Faccini A, Leuschner I, Formica S, Reis-Filho JS, Ambrosini V, Thway K, Franzoni M, Summersgill B, Marchelli R, Hrelia P, Cantelli-Forti G, Fanti S, Corradini R, Pession A, Shipley J.

Clin Cancer Res. 2012 Feb 1;18(3):796-807. doi: 10.1158/1078-0432.CCR-11-1981. Epub 2011 Nov 7.

46.

Dysfunctional γδ T cells contribute to impaired keratinocyte homeostasis in mouse models of obesity.

Taylor KR, Costanzo AE, Jameson JM.

J Invest Dermatol. 2011 Dec;131(12):2409-18. doi: 10.1038/jid.2011.241. Epub 2011 Aug 11.

47.

DFNA8/12 caused by TECTA mutations is the most identified subtype of nonsyndromic autosomal dominant hearing loss.

Hildebrand MS, Morín M, Meyer NC, Mayo F, Modamio-Hoybjor S, Mencía A, Olavarrieta L, Morales-Angulo C, Nishimura CJ, Workman H, DeLuca AP, del Castillo I, Taylor KR, Tompkins B, Goodman CW, Schrauwen I, Wesemael MV, Lachlan K, Shearer AE, Braun TA, Huygen PL, Kremer H, Van Camp G, Moreno F, Casavant TL, Smith RJ, Moreno-Pelayo MA.

Hum Mutat. 2011 Jul;32(7):825-34. doi: 10.1002/humu.21512. Epub 2011 Jun 7.

48.

Comprehensive genetic testing for hereditary hearing loss using massively parallel sequencing.

Shearer AE, DeLuca AP, Hildebrand MS, Taylor KR, Gurrola J 2nd, Scherer S, Scheetz TE, Smith RJ.

Proc Natl Acad Sci U S A. 2010 Dec 7;107(49):21104-9. doi: 10.1073/pnas.1012989107. Epub 2010 Nov 15.

49.

Gammadelta T cells are reduced and rendered unresponsive by hyperglycemia and chronic TNFalpha in mouse models of obesity and metabolic disease.

Taylor KR, Mills RE, Costanzo AE, Jameson JM.

PLoS One. 2010 Jul 2;5(7):e11422. doi: 10.1371/journal.pone.0011422.

50.

Gradients of strain and strain rate in the hollow muscular organs of soft-bodied animals.

Thompson JT, Taylor KR, Gentile C.

Biol Lett. 2010 Aug 23;6(4):482-5. doi: 10.1098/rsbl.2009.0978. Epub 2010 Jan 27.

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