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Responses to Quadrivalent Influenza Vaccine Reveal Distinct Circulating CD4+CXCR5+ T Cell Subsets in Men Living with HIV.

Cole ME, Saeed Z, Shaw AT, Guo Y, Höschler K, Winston A, Cooke GS, Fidler S, Taylor GP, Pollock KM.

Sci Rep. 2019 Oct 30;9(1):15650. doi: 10.1038/s41598-019-51961-9.


HTLV-1: the silent impact revealed.

Cook LBM, Taylor GP.

Lancet Infect Dis. 2019 Oct 21. pii: S1473-3099(19)30432-3. doi: 10.1016/S1473-3099(19)30432-3. [Epub ahead of print] No abstract available.


Non-invasive Detection of Antibodies to Human T-lymphotropic Viruses 1 and 2 using Oral Fluid.

Woo T, Rosadas C, Ijaz S, Dicks S, Tosswill JHC, Tedder RS, Taylor GP.

J Clin Microbiol. 2019 Oct 9. pii: JCM.01179-19. doi: 10.1128/JCM.01179-19. [Epub ahead of print]


Pregnancy does not adversely impact diagnostic tests for HTLV-1/2 infection.

Rosadas C, Tosswill JH, Tedder R, Taylor GP.

PLoS Negl Trop Dis. 2019 Sep 12;13(9):e0007736. doi: 10.1371/journal.pntd.0007736. eCollection 2019 Sep.


Mother-to-Child HTLV-1 Transmission: Unmet Research Needs.

Rosadas C, Taylor GP.

Front Microbiol. 2019 May 8;10:999. doi: 10.3389/fmicb.2019.00999. eCollection 2019. Review.


Enhanced T-cell maturation and monocyte aggregation are features of cellular inflammation in human T-lymphotropic virus type-1-associated myelopathy.

Saeed Z, Rowan A, Greiller C, Taylor GP, Pollock KM.

Clin Infect Dis. 2019 May 7. pii: ciz369. doi: 10.1093/cid/ciz369. [Epub ahead of print]


Molecular remissions are observed in chronic adult T cell leukemia/lymphoma in patients treated with mogamulizumab.

Cook LBM, Demontis MA, Sagawe S, Witkover A, Melamed A, Turpin J, Dillon R, Haddow J, Marks AJ, Bangham CRM, Fields P, Taylor GP, Rowan AG.

Haematologica. 2019 Apr 19. pii: haematol.2019.219253. doi: 10.3324/haematol.2019.219253. [Epub ahead of print]


Self-Flagellation as Possible Route of Human T-Cell Lymphotropic Virus Type-1 Transmission.

Tang AR, Taylor GP, Dhasmana D.

Emerg Infect Dis. 2019 Apr;25(4):811-813. doi: 10.3201/eid2504.180984.


Transmission of CMV, HTLV-1, and HIV through breastmilk.

Prendergast AJ, Goga AE, Waitt C, Gessain A, Taylor GP, Rollins N, Abrams EJ, Lyall EH, de Perre PV.

Lancet Child Adolesc Health. 2019 Apr;3(4):264-273. doi: 10.1016/S2352-4642(19)30024-0. Review.


Rapid onset and progression of myelopathy following an STI: a case for screening?

Caswell RJ, Nall P, Boothby M, Taylor GP.

Sex Transm Infect. 2019 Jun;95(4):244-245. doi: 10.1136/sextrans-2019-053978. Epub 2019 Mar 1.


Mogamulizumab versus investigator's choice of chemotherapy regimen in relapsed/refractory adult T-cell leukemia/lymphoma.

Phillips AA, Fields PA, Hermine O, Ramos JC, Beltran BE, Pereira J, Wandroo F, Feldman T, Taylor GP, Sawas A, Humphrey J, Kurman M, Moriya J, Dwyer K, Leoni M, Conlon K, Cook L, Gonsky J, Horwitz SM; 0761-009 Study Group.

Haematologica. 2019 May;104(5):993-1003. doi: 10.3324/haematol.2018.205096. Epub 2018 Dec 20.


Estimation of HTLV-1 vertical transmission cases in Brazil per annum.

Rosadas C, Malik B, Taylor GP, Puccioni-Sohler M.

PLoS Negl Trop Dis. 2018 Nov 12;12(11):e0006913. doi: 10.1371/journal.pntd.0006913. eCollection 2018 Nov.


DMS as an orthogonal separation to LC/ESI/MS/MS for quantifying isomeric cerebrosides in plasma and cerebrospinal fluid.

Xu H, Boucher FR, Nguyen TT, Taylor GP, Tomlinson JJ, Ortega RA, Simons B, Schlossmacher MG, Saunders-Pullman R, Shaw W, Bennett SAL.

J Lipid Res. 2019 Jan;60(1):200-211. doi: 10.1194/jlr.D089797. Epub 2018 Nov 9.


Histone H2A monoubiquitylation and p38-MAPKs regulate immediate-early gene-like reactivation of latent retrovirus HTLV-1.

Kulkarni A, Taylor GP, Klose RJ, Schofield CJ, Bangham CR.

JCI Insight. 2018 Oct 18;3(20). pii: 123196. doi: 10.1172/jci.insight.123196.


Decreased RORC expression and downstream signaling in HTLV-1-associated adult T-cell lymphoma/leukemia uncovers an antiproliferative IL17 link: A potential target for immunotherapy?

Subramanian K, Dierckx T, Khouri R, Menezes SM, Kagdi H, Taylor GP, Farre L, Bittencourt A, Kataoka K, Ogawa S, Van Weyenbergh J.

Int J Cancer. 2019 Apr 1;144(7):1664-1675. doi: 10.1002/ijc.31922. Epub 2018 Dec 18.


Phosphatidylinositol 3-kinase-δ (PI3K-δ) is a potential therapeutic target in adult T-cell leukemia-lymphoma.

Katsuya H, Cook LBM, Rowan AG, Satou Y, Taylor GP, Bangham CRM.

Biomark Res. 2018 Jul 18;6:24. doi: 10.1186/s40364-018-0138-7. eCollection 2018.


Can we reduce the incidence of adult T-cell leukaemia/lymphoma? Cost-effectiveness of human T-lymphotropic virus type 1 (HTLV-1) antenatal screening in the United Kingdom.

Malik B, Taylor GP.

Br J Haematol. 2019 Mar;184(6):1040-1043. doi: 10.1111/bjh.15234. Epub 2018 Apr 20. No abstract available.


Protecting health care in armed conflict: action towards accountability.

Taylor GP, Castro I, Rebergen C, Rycroft M, Nuwayhid I, Rubenstein L, Tarakji A, Modirzadeh N, Venters H, Jabbour S.

Lancet. 2018 Apr 14;391(10129):1477-1478. doi: 10.1016/S0140-6736(18)30610-X. No abstract available.


Optimising the collection of female genital tract fluid for cytokine analysis in pregnant women.

Short CS, Quinlan R, Bennett P, Shattock RJ, Taylor GP.

J Immunol Methods. 2018 Jul;458:15-20. doi: 10.1016/j.jim.2018.03.014. Epub 2018 Apr 3.


Human T-lymphotrophic virus-a neglected cause of chronic pain?

Kemp HI, Rice ASC, Adonis A, Davies NWS, Taylor GP.

Pain. 2018 Aug;159(8):1433-1437. doi: 10.1097/j.pain.0000000000001214. Review. No abstract available.


Switching and loss of cellular cytokine producing capacity characterize in vivo viral infection and malignant transformation in human T- lymphotropic virus type 1 infection.

Kagdi H, Demontis MA, Ramos JC, Taylor GP.

PLoS Pathog. 2018 Feb 14;14(2):e1006861. doi: 10.1371/journal.ppat.1006861. eCollection 2018 Feb.


Human T-cell lymphotropic virus (HTLV)-associated encephalopathy: an under-recognised cause of acute encephalitis? Case series and literature review.

Crawshaw AA, Dhasmana D, Jones B, Gabriel CM, Sturman S, Davies NWS, Taylor GP.

J Neurol. 2018 Apr;265(4):871-879. doi: 10.1007/s00415-018-8777-z. Epub 2018 Feb 8. Review.


Human T-lymphotropic virus type 1 infection and solid organ transplantation.

Taylor GP.

Rev Med Virol. 2018 Mar;28(2). doi: 10.1002/rmv.1970. Epub 2018 Jan 29. Review.


Protease inhibitors and preterm delivery: another piece in the puzzle.

Favarato G, Townsend CL, Bailey H, Peters H, Tookey PA, Taylor GP, Thorne C.

AIDS. 2018 Jan 14;32(2):243-252. doi: 10.1097/QAD.0000000000001694.


Long-term clinical remission maintained after cessation of zidovudine and interferon-α therapy in chronic adult T-cell leukemia/lymphoma.

Cook LB, Rowan AG, Demontis MA, Sagawe S, Gillet NA, Melamed A, Greiller C, Witkover A, Bangham CRM, Taylor GP.

Int J Hematol. 2018 Mar;107(3):378-382. doi: 10.1007/s12185-017-2361-7. Epub 2017 Oct 31.


Interpretation of low reactivity in the Abbott Architect rHTLV I/II assay.

Tosswill JHC, Taylor GP.

Transfus Med. 2018 Aug;28(4):326-330. doi: 10.1111/tme.12482. Epub 2017 Oct 24.


Glucose Metabolism and Oxygen Availability Govern Reactivation of the Latent Human Retrovirus HTLV-1.

Kulkarni A, Mateus M, Thinnes CC, McCullagh JS, Schofield CJ, Taylor GP, Bangham CRM.

Cell Chem Biol. 2017 Nov 16;24(11):1377-1387.e3. doi: 10.1016/j.chembiol.2017.08.016. Epub 2017 Sep 28.


Antiretroviral therapy in pregnant women living with HIV: a clinical practice guideline.

Siemieniuk RAC, Lytvyn L, Mah Ming J, Mullen RM, Anam F, Otieno T, Guyatt GH, Taylor GP, Beltrán-Arroyave C, Okwen PM, Nduati R, Kinuthia J, Luma HN, Kirpalani H, Merglen A, Lesi OA, Vandvik PO, Agoritsas T, Bewley S.

BMJ. 2017 Sep 11;358:j3961. doi: 10.1136/bmj.j3961. No abstract available.


HTLV-1 is predominantly sexually transmitted in Salvador, the city with the highest HTLV-1 prevalence in Brazil.

Nunes D, Boa-Sorte N, Grassi MF, Taylor GP, Teixeira MG, Barreto ML, Dourado I, Galvão-Castro B.

PLoS One. 2017 Feb 3;12(2):e0171303. doi: 10.1371/journal.pone.0171303. eCollection 2017.


Risk stratification of adult T-cell leukemia/lymphoma using immunophenotyping.

Kagdi HH, Demontis MA, Fields PA, Ramos JC, Bangham CR, Taylor GP.

Cancer Med. 2017 Jan;6(1):298-309. doi: 10.1002/cam4.928. Epub 2016 Dec 30.


T Cell Receptor Vβ Staining Identifies the Malignant Clone in Adult T cell Leukemia and Reveals Killing of Leukemia Cells by Autologous CD8+ T cells.

Rowan AG, Witkover A, Melamed A, Tanaka Y, Cook LB, Fields P, Taylor GP, Bangham CR.

PLoS Pathog. 2016 Nov 28;12(11):e1006030. doi: 10.1371/journal.ppat.1006030. eCollection 2016 Nov.


Reducing the global burden of HTLV-1 infection: An agenda for research and action.

Willems L, Hasegawa H, Accolla R, Bangham C, Bazarbachi A, Bertazzoni U, Carneiro-Proietti AB, Cheng H, Chieco-Bianchi L, Ciminale V, Coelho-Dos-Reis J, Esparza J, Gallo RC, Gessain A, Gotuzzo E, Hall W, Harford J, Hermine O, Jacobson S, Macchi B, Macpherson C, Mahieux R, Matsuoka M, Murphy E, Peloponese JM, Simon V, Tagaya Y, Taylor GP, Watanabe T, Yamano Y.

Antiviral Res. 2017 Jan;137:41-48. doi: 10.1016/j.antiviral.2016.10.015. Epub 2016 Nov 11. Review.


Evidence of Brain Inflammation in Patients with Human T-Lymphotropic Virus Type 1-Associated Myelopathy (HAM): A Pilot, Multimodal Imaging Study Using 11C-PBR28 PET, MR T1-Weighted, and Diffusion-Weighted Imaging.

Dimber R, Guo Q, Bishop C, Adonis A, Buckley A, Kocsis A, Owen D, Kalk N, Newbould R, Gunn RN, Rabiner EA, Taylor GP.

J Nucl Med. 2016 Dec;57(12):1905-1912. Epub 2016 Aug 25.


Assessing Walking Ability in People with HTLV-1-Associated Myelopathy Using the 10 Meter Timed Walk and the 6 Minute Walk Test.

Adonis A, Taylor GP.

PLoS One. 2016 Jun 23;11(6):e0157132. doi: 10.1371/journal.pone.0157132. eCollection 2016.


CADM1/TSLC1 Identifies HTLV-1-Infected Cells and Determines Their Susceptibility to CTL-Mediated Lysis.

Manivannan K, Rowan AG, Tanaka Y, Taylor GP, Bangham CR.

PLoS Pathog. 2016 Apr 22;12(4):e1005560. doi: 10.1371/journal.ppat.1005560. eCollection 2016 Apr.


Effect of Pulsed Methylprednisolone on Pain, in Patients with HTLV-1-Associated Myelopathy.

Buell KG, Puri A, Demontis MA, Short CL, Adonis A, Haddow J, Martin F, Dhasmana D, Taylor GP.

PLoS One. 2016 Apr 14;11(4):e0152557. doi: 10.1371/journal.pone.0152557. eCollection 2016.


Long Terminal Repeat Circular DNA as Markers of Active Viral Replication of Human T Lymphotropic Virus-1 in Vivo.

Fox JM, Hilburn S, Demontis MA, Brighty DW, Rios Grassi MF, Galvão-Castro B, Taylor GP, Martin F.

Viruses. 2016 Mar 14;8(3):80. doi: 10.3390/v8030080.


PD-1 Expression and Cytokine Secretion Profiles of Mycobacterium tuberculosis-Specific CD4+ T-Cell Subsets; Potential Correlates of Containment in HIV-TB Co-Infection.

Pollock KM, Montamat-Sicotte DJ, Grass L, Cooke GS, Kapembwa MS, Kon OM, Sampson RD, Taylor GP, Lalvani A.

PLoS One. 2016 Jan 12;11(1):e0146905. doi: 10.1371/journal.pone.0146905. eCollection 2016.


Rapid dissemination of human T-lymphotropic virus type 1 during primary infection in transplant recipients.

Cook LB, Melamed A, Demontis MA, Laydon DJ, Fox JM, Tosswill JH, de Freitas D, Price AD, Medcalf JF, Martin F, Neuberger JM, Bangham CR, Taylor GP.

Retrovirology. 2016 Jan 8;13:3. doi: 10.1186/s12977-015-0236-7.


Seroprevalence of HTLV-1 and HTLV-2 amongst mothers and children in Malawi within the context of a systematic review and meta-analysis of HTLV seroprevalence in Africa.

Fox JM, Mutalima N, Molyneux E, Carpenter LM, Taylor GP, Bland M, Newton R, Martin F.

Trop Med Int Health. 2016 Mar;21(3):312-24. doi: 10.1111/tmi.12659. Epub 2016 Feb 3. Review.


Immune Compromise in HIV-1/HTLV-1 Coinfection With Paradoxical Resolution of CD4 Lymphocytosis During Antiretroviral Therapy: A Case Report.

Rockwood N, Cook L, Kagdi H, Basnayake S, Bangham CR, Pozniak AL, Taylor GP.

Medicine (Baltimore). 2015 Dec;94(50):e2275. doi: 10.1097/MD.0000000000002275.


HTLV-1 drives vigorous clonal expansion of infected CD8(+) T cells in natural infection.

Melamed A, Laydon DJ, Al Khatib H, Rowan AG, Taylor GP, Bangham CR.

Retrovirology. 2015 Nov 9;12:91. doi: 10.1186/s12977-015-0221-1.


The risk of viral rebound in the year after delivery in women remaining on antiretroviral therapy.

Huntington S, Thorne C, Newell ML, Anderson J, Taylor GP, Pillay D, Hill T, Tookey PA, Sabin C; UK Collaborative HIV Cohort (UK CHIC) Study and the UK and Ireland National Study of HIV in Pregnancy and Childhood (NSHPC).

AIDS. 2015 Nov;29(17):2269-78. doi: 10.1097/QAD.0000000000000826.


No Need for Lopinavir Dose Adjustment during Pregnancy: a Population Pharmacokinetic and Exposure-Response Analysis in Pregnant and Nonpregnant HIV-Infected Subjects.

Salem AH, Jones AK, Santini-Oliveira M, Taylor GP, Patterson KB, Nilius AM, Klein CE.

Antimicrob Agents Chemother. 2015 Nov 2;60(1):400-8. doi: 10.1128/AAC.01197-15. Print 2016 Jan.


Timed walk as primary outcome measure of treatment response in clinical trials for HTLV-1-associated myelopathy: a feasibility study.

Martin F, Inoue E, Cortese IC, de Almeida Kruschewsky R, Adonis A, Grassi MF, Galvão-Castro B, Jacobson S, Yamano Y, Taylor GP, Bland M.

Pilot Feasibility Stud. 2015 Oct 23;1:35. eCollection 2015.


Comparison of Immune Profiles in Fetal Hearts with Idiopathic Dilated Cardiomyopathy, Maternal Autoimmune-Associated Dilated Cardiomyopathy and the Normal Fetus.

Nield LE, von Both I, Popel N, Strachan K, Manlhiot C, Shannon P, McCrindle BW, Atkinson A, Miner SE, Jaeggi ET, Taylor GP.

Pediatr Cardiol. 2016 Feb;37(2):353-63. doi: 10.1007/s00246-015-1284-4. Epub 2015 Oct 20.


Differences in antigen-specific CD4+ responses to opportunistic infections in HIV infection.

Pollock KM, Montamat-Sicotte DJ, Cooke GS, Kapembwa MS, Kon OM, Grass L, Sampson RD, Taylor GP, Lalvani A.

Immun Inflamm Dis. 2015 Sep;3(3):141-53. doi: 10.1002/iid3.50. Epub 2015 Apr 29.


Treatment of adult T-cell leukaemia/lymphoma: is the virus a target?

Cook LB, Taylor GP.

Curr Opin Infect Dis. 2015 Dec;28(6):583-8. doi: 10.1097/QCO.0000000000000207. Review.


Lopinavir and atazanavir in pregnancy: comparable infant outcomes, virological efficacies and preterm delivery rates.

Perry ME, Taylor GP, Sabin CA, Conway K, Flanagan S, Dwyer E, Stevenson J, Mulka L, McKendry A, Williams E, Barbour A, Dermont S, Roedling S, Shah R, Anderson J, Rodgers M, Wood C, Sarner L, Hay P, Hawkins D, deRuiter A.

HIV Med. 2016 Jan;17(1):28-35. doi: 10.1111/hiv.12277. Epub 2015 Jul 22.

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