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Disruption of type III interferon genes Ifnl2 and Ifnl3 recapitulates loss of the type III IFN receptor in the mucosal antiviral response.

Peterson ST, Kennedy EA, Brigleb PH, Taylor GM, Urbanek K, Bricker TL, Lee S, Shin H, Dermody TS, Boon ACM, Baldridge MT.

J Virol. 2019 Aug 28. pii: JVI.01073-19. doi: 10.1128/JVI.01073-19. [Epub ahead of print]


Transcriptional Terminators Allow Leak-Free Chromosomal Integration of Genetic Constructs in Cyanobacteria.

Kelly CL, Taylor GM, Šatkutė A, Dekker L, Heap JT.

Microorganisms. 2019 Aug 16;7(8). pii: E263. doi: 10.3390/microorganisms7080263.


A tubo-ovarian abscess mimicking an appendiceal abscess: a rare presentation of Streptococcus agalactiae.

Taylor GM, Erlich AH, Wallace LC, Williams V, Ali RM, Zygowiec JP.

Oxf Med Case Reports. 2019 Aug 1;2019(8). pii: omz071. doi: 10.1093/omcr/omz071.


Prescribing Prevalence, Effectiveness, and Mental Health Safety of Smoking Cessation Medicines in Patients With Mental Disorders.

Taylor GMJ, Itani T, Thomas KH, Rai D, Jones T, Windmeijer F, Martin RM, Munafò MR, Davies NM, Taylor AE.

Nicotine Tob Res. 2019 Jul 10. pii: ntz072. doi: 10.1093/ntr/ntz072. [Epub ahead of print]


Breast abscess in a competitive high school swimmer: a case of toxic shock syndrome.

Taylor GM, Vieder SJ, Cooley CN, Fan WC, Alper ME.

Oxf Med Case Reports. 2019 Jun 28;2019(6):omz054. doi: 10.1093/omcr/omz054. eCollection 2019 Jun.


High-output congestive heart failure: a potentially deadly complication of thyroid storm.

Taylor GM, Pop AMC, McDowell EL.

Oxf Med Case Reports. 2019 Jun 14;2019(6):omz045. doi: 10.1093/omcr/omz045. eCollection 2019 Jun.


Perianal abscess in a 2-year-old presenting with a febrile seizure and swelling of the perineum.

Taylor GM, Erlich AH.

Oxf Med Case Reports. 2019 Jan 24;2019(1):omy116. doi: 10.1093/omcr/omy116. eCollection 2019 Jan.


Leprosy at the edge of Europe-Biomolecular, isotopic and osteoarchaeological findings from medieval Ireland.

Taylor GM, Murphy EM, Mendum TA, Pike AWG, Linscott B, Wu H, O'Grady J, Richardson H, O'Donovan E, Troy C, Stewart GR.

PLoS One. 2018 Dec 26;13(12):e0209495. doi: 10.1371/journal.pone.0209495. eCollection 2018.


Does smoking cause poor mental health?

Taylor GMJ, Munafò MR.

Lancet Psychiatry. 2019 Jan;6(1):2-3. doi: 10.1016/S2215-0366(18)30459-0. Epub 2018 Dec 5. No abstract available.


Start-Stop Assembly: a functionally scarless DNA assembly system optimized for metabolic engineering.

Taylor GM, Mordaka PM, Heap JT.

Nucleic Acids Res. 2019 Feb 20;47(3):e17. doi: 10.1093/nar/gky1182.


Molecular Analyses in a Rabbit Model of Craniosynostosis: Likely Exclusion of Known Candidate Genes as the Loci of Origin.

Gilbert JR, Taylor GM, Losee JE, Mooney MP, Cooper GM.

Cleft Palate Craniofac J. 2019 Jul;56(6):786-790. doi: 10.1177/1055665618808623. Epub 2018 Oct 28.


Septic shock secondary to acute bacterial prostatitis in an HIV-positive male: a novel presentation.

Taylor GM, Paratore DM.

Oxf Med Case Reports. 2018 Oct 17;2018(11):omy086. doi: 10.1093/omcr/omy086. eCollection 2018 Nov.


What about treatment of smoking to improve survival and reduce depression?

Taylor GMJ, Munafò MR.

Lancet Psychiatry. 2018 Jun;5(6):464. doi: 10.1016/S2215-0366(18)30132-9. No abstract available.


Response to: Long-term smoking cessation: from general practice to public health.

Taylor GMJ, Davies NM.

Int J Epidemiol. 2018 Aug 1;47(4):1356. doi: 10.1093/ije/dyy084. No abstract available.


Ancient genomes reveal a high diversity of Mycobacterium leprae in medieval Europe.

Schuenemann VJ, Avanzi C, Krause-Kyora B, Seitz A, Herbig A, Inskip S, Bonazzi M, Reiter E, Urban C, Dangvard Pedersen D, Taylor GM, Singh P, Stewart GR, Velemínský P, Likovsky J, Marcsik A, Molnár E, Pálfi G, Mariotti V, Riga A, Belcastro MG, Boldsen JL, Nebel A, Mays S, Donoghue HD, Zakrzewski S, Benjak A, Nieselt K, Cole ST, Krause J.

PLoS Pathog. 2018 May 10;14(5):e1006997. doi: 10.1371/journal.ppat.1006997. eCollection 2018 May.


A Rhamnose-Inducible System for Precise and Temporal Control of Gene Expression in Cyanobacteria.

Kelly CL, Taylor GM, Hitchcock A, Torres-Méndez A, Heap JT.

ACS Synth Biol. 2018 Apr 20;7(4):1056-1066. doi: 10.1021/acssynbio.7b00435. Epub 2018 Apr 2.


Fournier gangrene: a rare case of necrotizing fasciitis of the entire right hemi-pelvis in a diabetic female.

Taylor GM, Hess DV.

Oxf Med Case Reports. 2018 Feb 9;2018(2):omx094. doi: 10.1093/omcr/omx094. eCollection 2018 Feb.


The effects of prescribing varenicline on two-year health outcomes: an observational cohort study using electronic medical records.

Davies NM, Taylor GMJ, Taylor AE, Jones T, Martin RM, Munafò MR, Windmeijer F, Thomas KH.

Addiction. 2018 Jun;113(6):1105-1116. doi: 10.1111/add.14146. Epub 2018 Feb 20.


Molecular Analysis of Gli3, Ihh, Rab23, and Jag1 in a Rabbit Model of Craniosynostosis: Likely Exclusion as the Loci of Origin.

Gilbert JR, Taylor GM, Losee JE, Mooney MP, Cooper GM.

Cleft Palate Craniofac J. 2018 Mar;55(3):375-382. doi: 10.1177/1055665617739001. Epub 2017 Dec 18.


The effectiveness of varenicline versus nicotine replacement therapy on long-term smoking cessation in primary care: a prospective cohort study of electronic medical records.

Taylor GMJ, Taylor AE, Thomas KH, Jones T, Martin RM, Munafò MR, Windmeijer F, Davies NM.

Int J Epidemiol. 2017 Dec 1;46(6):1948-1957. doi: 10.1093/ije/dyx109.


Leprosy in pre-Norman Suffolk, UK: biomolecular and geochemical analysis of the woman from Hoxne.

Inskip S, Taylor GM, Anderson S, Stewart G.

J Med Microbiol. 2017 Nov;66(11):1640-1649. doi: 10.1099/jmm.0.000606. Epub 2017 Oct 6.


Internet-based interventions for smoking cessation.

Taylor GMJ, Dalili MN, Semwal M, Civljak M, Sheikh A, Car J.

Cochrane Database Syst Rev. 2017 Sep 4;9:CD007078. doi: 10.1002/14651858.CD007078.pub5. Review.


TLR4 Inactivation in Myeloid Cells Accelerates Bone Healing of a Calvarial Defect Model in Mice.

Wang D, Gilbert JR, Taylor GM, Sodhi CP, Hackam DJ, Losee JE, Billiar TR, Cooper GM.

Plast Reconstr Surg. 2017 Aug;140(2):296e-306e. doi: 10.1097/PRS.0000000000003541.


How to compare instrumental variable and conventional regression analyses using negative controls and bias plots.

Davies NM, Thomas KH, Taylor AE, Taylor GMJ, Martin RM, Munafò MR, Windmeijer F.

Int J Epidemiol. 2017 Dec 1;46(6):2067-2077. doi: 10.1093/ije/dyx014.


Enhanced Calvarial Bone Healing in CD11c-TLR4-/- and MyD88-/- Mice.

Wang D, Taylor GM, Gilbert JR, Losee JE, Sodhi CP, Hackam DJ, Billiar TR, Cooper GM.

Plast Reconstr Surg. 2017 Apr;139(4):933e-940e. doi: 10.1097/PRS.0000000000003206.


Molecular Analysis of Ephrin A4 and Ephrin B1 in a Rabbit Model of Craniosynostosis: Likely Exclusion as the Loci of Origin.

Taylor GM, Cooper GM, Losee JE, Mooney MP, Gilbert J.

Cleft Palate Craniofac J. 2018 Aug;55(7):1020-1025. doi: 10.1597/16-135. Epub 2018 Feb 22.


Investigation of a Medieval Pilgrim Burial Excavated from the Leprosarium of St Mary Magdalen Winchester, UK.

Roffey S, Tucker K, Filipek-Ogden K, Montgomery J, Cameron J, O'Connell T, Evans J, Marter P, Taylor GM.

PLoS Negl Trop Dis. 2017 Jan 26;11(1):e0005186. doi: 10.1371/journal.pntd.0005186. eCollection 2017 Jan.


The Human 343delT HSPB5 Chaperone Associated with Early-onset Skeletal Myopathy Causes Defects in Protein Solubility.

Mitzelfelt KA, Limphong P, Choi MJ, Kondrat FD, Lai S, Kolander KD, Kwok WM, Dai Q, Grzybowski MN, Zhang H, Taylor GM, Lui Q, Thao MT, Hudson JA, Barresi R, Bushby K, Jungbluth H, Wraige E, Geurts AM, Benesch JL, Riedel M, Christians ES, Minella AC, Benjamin IJ.

J Biol Chem. 2016 Jul 15;291(29):14939-53. doi: 10.1074/jbc.M116.730481. Epub 2016 May 19.


The Green Prescription Active Families programme in Taranaki, New Zealand 2007-2009: Did it reach children in need?

Anderson YC, Taylor GM, Grant CC, Fulton RB, Hofman PL.

J Prim Health Care. 2015 Sep 1;7(3):192-7.


Osteological, biomolecular and geochemical examination of an early anglo-saxon case of lepromatous leprosy.

Inskip SA, Taylor GM, Zakrzewski SR, Mays SA, Pike AW, Llewellyn G, Williams CM, Lee OY, Wu HH, Minnikin DE, Besra GS, Stewart GR.

PLoS One. 2015 May 13;10(5):e0124282. doi: 10.1371/journal.pone.0124282. eCollection 2015.


Modeling HLA associations with EBV-positive and -negative Hodgkin lymphoma suggests distinct mechanisms in disease pathogenesis.

Johnson PC, McAulay KA, Montgomery D, Lake A, Shield L, Gallagher A, Little AM, Shah A, Marsh SG, Taylor GM, Jarrett RF.

Int J Cancer. 2015 Sep 1;137(5):1066-75. doi: 10.1002/ijc.29467. Epub 2015 Feb 20.


A meta-analysis of Hodgkin lymphoma reveals 19p13.3 TCF3 as a novel susceptibility locus.

Cozen W, Timofeeva MN, Li D, Diepstra A, Hazelett D, Delahaye-Sourdeix M, Edlund CK, Franke L, Rostgaard K, Van Den Berg DJ, Cortessis VK, Smedby KE, Glaser SL, Westra HJ, Robison LL, Mack TM, Ghesquieres H, Hwang AE, Nieters A, de Sanjose S, Lightfoot T, Becker N, Maynadie M, Foretova L, Roman E, Benavente Y, Rand KA, Nathwani BN, Glimelius B, Staines A, Boffetta P, Link BK, Kiemeney L, Ansell SM, Bhatia S, Strong LC, Galan P, Vatten L, Habermann TM, Duell EJ, Lake A, Veenstra RN, Visser L, Liu Y, Urayama KY, Montgomery D, Gaborieau V, Weiss LM, Byrnes G, Lathrop M, Cocco P, Best T, Skol AD, Adami HO, Melbye M, Cerhan JR, Gallagher A, Taylor GM, Slager SL, Brennan P, Coetzee GA, Conti DV, Onel K, Jarrett RF, Hjalgrim H, van den Berg A, McKay JD.

Nat Commun. 2014 Jun 12;5:3856. doi: 10.1038/ncomms4856.


Mycobacterium leprae genomes from a British medieval leprosy hospital: towards understanding an ancient epidemic.

Mendum TA, Schuenemann VJ, Roffey S, Taylor GM, Wu H, Singh P, Tucker K, Hinds J, Cole ST, Kierzek AM, Nieselt K, Krause J, Stewart GR.

BMC Genomics. 2014 Apr 8;15:270. doi: 10.1186/1471-2164-15-270.


Genome-wide RNAi screen identifies novel host proteins required for alphavirus entry.

Ooi YS, Stiles KM, Liu CY, Taylor GM, Kielian M.

PLoS Pathog. 2013;9(12):e1003835. doi: 10.1371/journal.ppat.1003835. Epub 2013 Dec 19.


Genome-wide comparison of medieval and modern Mycobacterium leprae.

Schuenemann VJ, Singh P, Mendum TA, Krause-Kyora B, Jäger G, Bos KI, Herbig A, Economou C, Benjak A, Busso P, Nebel A, Boldsen JL, Kjellström A, Wu H, Stewart GR, Taylor GM, Bauer P, Lee OY, Wu HH, Minnikin DE, Besra GS, Tucker K, Roffey S, Sow SO, Cole ST, Nieselt K, Krause J.

Science. 2013 Jul 12;341(6142):179-83. doi: 10.1126/science.1238286. Epub 2013 Jun 13.


Detection and strain typing of ancient Mycobacterium leprae from a medieval leprosy hospital.

Taylor GM, Tucker K, Butler R, Pike AW, Lewis J, Roffey S, Marter P, Lee OY, Wu HH, Minnikin DE, Besra GS, Singh P, Cole ST, Stewart GR.

PLoS One. 2013 Apr 30;8(4):e62406. doi: 10.1371/journal.pone.0062406. Print 2013.


Parkinson's disease is not associated with gastrointestinal myenteric ganglion neuron loss.

Annerino DM, Arshad S, Taylor GM, Adler CH, Beach TG, Greene JG.

Acta Neuropathol. 2012 Nov;124(5):665-80. doi: 10.1007/s00401-012-1040-2. Epub 2012 Sep 2.


HLA-DPβ1 Asp84-Lys69 antigen-binding signature predicts event-free survival in childhood B-cell precursor acute lymphoblastic leukaemia: results from the MRC UKALL XI childhood ALL trial.

Taylor GM, Wade R, Hussain A, Thompson P, Hann I, Gibson B, Eden T, Richards S.

Blood Cancer J. 2012 Jul;2(7):e80. doi: 10.1038/bcj.2012.25. Epub 2012 Jul 20.


Alpha-synuclein transgenic mice display age-related slowing of gastrointestinal motility associated with transgene expression in the vagal system.

Noorian AR, Rha J, Annerino DM, Bernhard D, Taylor GM, Greene JG.

Neurobiol Dis. 2012 Oct;48(1):9-19. doi: 10.1016/j.nbd.2012.06.005. Epub 2012 Jun 18.


Safety evaluation of a recombinant plasmin derivative lacking kringles 2-5 and rt-PA in a rat model of transient ischemic stroke.

Crumrine RC, Marder VJ, Taylor GM, LaManna JC, Tsipis CP, Novokhatny V, Scuderi P, Petteway SR Jr, Arora V.

Exp Transl Stroke Med. 2012 May 16;4(1):10. doi: 10.1186/2040-7378-4-10.


Intra-arterial administration of recombinant tissue-type plasminogen activator (rt-PA) causes more intracranial bleeding than does intravenous rt-PA in a transient rat middle cerebral artery occlusion model.

Crumrine RC, Marder VJ, Taylor GM, Lamanna JC, Tsipis CP, Scuderi P, Petteway SR Jr, Arora V.

Exp Transl Stroke Med. 2011 Sep 20;3(1):10. doi: 10.1186/2040-7378-3-10.


Endoplasmic reticulum stress causes EBV lytic replication.

Taylor GM, Raghuwanshi SK, Rowe DT, Wadowsky RM, Rosendorff A.

Blood. 2011 Nov 17;118(20):5528-39. doi: 10.1182/blood-2011-04-347112. Epub 2011 Aug 17.


Multiple loci variable number tandem repeat (VNTR) analysis (MLVA) of Mycobacterium leprae isolates amplified from European archaeological human remains with lepromatous leprosy.

Taylor GM, Donoghue HD.

Microbes Infect. 2011 Oct;13(11):923-9. doi: 10.1016/j.micinf.2011.05.003. Epub 2011 May 27.


Neurochemical phenotypes of myenteric neurons in the rhesus monkey.

Noorian AR, Taylor GM, Annerino DM, Greene JG.

J Comp Neurol. 2011 Dec 1;519(17):3387-401. doi: 10.1002/cne.22679.


HLA-A alleles and infectious mononucleosis suggest a critical role for cytotoxic T-cell response in EBV-related Hodgkin lymphoma.

Hjalgrim H, Rostgaard K, Johnson PC, Lake A, Shield L, Little AM, Ekstrom-Smedby K, Adami HO, Glimelius B, Hamilton-Dutoit S, Kane E, Taylor GM, McConnachie A, Ryder LP, Sundstrom C, Andersen PS, Chang ET, Alexander FE, Melbye M, Jarrett RF.

Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6400-5. doi: 10.1073/pnas.0915054107. Epub 2010 Mar 22.


Genetic variation in the folate metabolic pathway and risk of childhood leukemia.

Lightfoot TJ, Johnston WT, Painter D, Simpson J, Roman E, Skibola CF, Smith MT, Allan JM, Taylor GM; United Kingdom Childhood Cancer Study.

Blood. 2010 May 13;115(19):3923-9. doi: 10.1182/blood-2009-10-249722. Epub 2010 Jan 25.


Comparative genomic and phylogeographic analysis of Mycobacterium leprae.

Monot M, Honoré N, Garnier T, Zidane N, Sherafi D, Paniz-Mondolfi A, Matsuoka M, Taylor GM, Donoghue HD, Bouwman A, Mays S, Watson C, Lockwood D, Khamesipour A, Dowlati Y, Jianping S, Rea TH, Vera-Cabrera L, Stefani MM, Banu S, Macdonald M, Sapkota BR, Spencer JS, Thomas J, Harshman K, Singh P, Busso P, Gattiker A, Rougemont J, Brennan PJ, Cole ST.

Nat Genet. 2009 Dec;41(12):1282-9. doi: 10.1038/ng.477. Epub 2009 Nov 1. Erratum in: Nat Genet. 2010 Apr;42(4):361. Khamispour, Ali [corrected to Khamesipour, Ali].


Relationship between HLA-DP supertype and survival in childhood acute lymphoblastic leukaemia: evidence for selective loss of immunological control of residual disease?

Taylor GM, Richards S, Wade R, Hussain A, Simpson J, Hill F, Mitchell C, Eden T; UKCCS and CCLG Investigators.

Br J Haematol. 2009 Apr;145(1):87-95. doi: 10.1111/j.1365-2141.2008.07571.x. Epub 2009 Jan 16.


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