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Items: 1 to 50 of 102

1.

In silico modeling of oxygen-enhanced MRI of specific ventilation.

Kang W, Tawhai MH, Clark AR, Sá RC, Geier ET, Prisk GK, Burrowes KS.

Physiol Rep. 2018 Apr;6(7):e13659. doi: 10.14814/phy2.13659.

2.

Metrics of lung tissue heterogeneity depend on BMI but not age.

Subramaniam K, Clark AR, Hoffman EA, Tawhai MH.

J Appl Physiol (1985). 2018 Aug 1;125(2):328-339. doi: 10.1152/japplphysiol.00510.2016. Epub 2018 Feb 22.

PMID:
29470150
3.

Next-generation, personalised, model-based critical care medicine: a state-of-the art review of in silico virtual patient models, methods, and cohorts, and how to validation them.

Chase JG, Preiser JC, Dickson JL, Pironet A, Chiew YS, Pretty CG, Shaw GM, Benyo B, Moeller K, Safaei S, Tawhai M, Hunter P, Desaive T.

Biomed Eng Online. 2018 Feb 20;17(1):24. doi: 10.1186/s12938-018-0455-y. Review.

4.

Gravity outweighs the contribution of structure to passive ventilation-perfusion matching in the supine adult human lung.

Kang W, Clark AR, Tawhai MH.

J Appl Physiol (1985). 2018 Jan 1;124(1):23-33. doi: 10.1152/japplphysiol.00791.2016. Epub 2017 Oct 19.

PMID:
29051337
5.

Parenchymal strain heterogeneity during oscillatory ventilation: why two frequencies are better than one.

Herrmann J, Tawhai MH, Kaczka DW.

J Appl Physiol (1985). 2018 Mar 1;124(3):653-663. doi: 10.1152/japplphysiol.00615.2017. Epub 2017 Oct 19.

PMID:
29051332
6.

Evidence for age-dependent air-space enlargement contributing to loss of lung tissue elastic recoil pressure and increased shear modulus in older age.

Subramaniam K, Kumar H, Tawhai MH.

J Appl Physiol (1985). 2017 Jul 1;123(1):79-87. doi: 10.1152/japplphysiol.00208.2016. Epub 2017 Apr 27.

7.

Association of Placental Jets and Mega-Jets With Reduced Villous Density.

Saghian R, James JL, Tawhai MH, Collins SL, Clark AR.

J Biomech Eng. 2017 May 1;139(5). doi: 10.1115/1.4036145.

PMID:
28267189
8.

Lobe based image reconstruction in Electrical Impedance Tomography.

Schullcke B, Gong B, Krueger-Ziolek S, Tawhai M, Adler A, Mueller-Lisse U, Moeller K.

Med Phys. 2017 Feb;44(2):426-436. doi: 10.1002/mp.12038. Epub 2017 Jan 25.

PMID:
28121374
9.

The impact of endoscopic sinus surgery on paranasal physiology in simulated sinus cavities.

Jain R, Kumar H, Tawhai M, Douglas R.

Int Forum Allergy Rhinol. 2017 Mar;7(3):248-255. doi: 10.1002/alr.21879. Epub 2016 Nov 21.

PMID:
27869357
10.

Regional gas transport in the heterogeneous lung during oscillatory ventilation.

Herrmann J, Tawhai MH, Kaczka DW.

J Appl Physiol (1985). 2016 Dec 1;121(6):1306-1318. doi: 10.1152/japplphysiol.00097.2016. Epub 2016 Oct 7.

11.

Automatic construction of subject-specific human airway geometry including trifurcations based on a CT-segmented airway skeleton and surface.

Miyawaki S, Tawhai MH, Hoffman EA, Wenzel SE, Lin CL.

Biomech Model Mechanobiol. 2017 Apr;16(2):583-596. doi: 10.1007/s10237-016-0838-6. Epub 2016 Oct 4.

12.

A multiscale model of placental oxygen exchange: The effect of villous tree structure on exchange efficiency.

Lin M, Mauroy B, James JL, Tawhai MH, Clark AR.

J Theor Biol. 2016 Nov 7;408:1-12. doi: 10.1016/j.jtbi.2016.06.037. Epub 2016 Jul 1.

PMID:
27378004
13.

Airflow in the Human Nasal Passage and Sinuses of Chronic Rhinosinusitis Subjects.

Kumar H, Jain R, Douglas RG, Tawhai MH.

PLoS One. 2016 Jun 1;11(6):e0156379. doi: 10.1371/journal.pone.0156379. eCollection 2016.

14.

Simulation of Forced Expiration in a Biophysical Model, With Homogeneous and Clustered Bronchoconstriction.

Hedges KL, Tawhai MH.

J Biomech Eng. 2016 Jun;138(6):061008. doi: 10.1115/1.4033475.

15.

Phenotype, endotype and patient-specific computational modelling for optimal treatment design in asthma.

Donovan GM, Tawhai MH.

Drug Discov Today Dis Models. 2015 Spring;15:23-27. Epub 2014 Apr 29.

16.

Breathing Easier: Model-based decision support for respiratory care looks beyond tomorrow.

Tawhai M, Chase JG.

IEEE Pulse. 2015 Sep-Oct;6(5):10-5. doi: 10.1109/MPUL.2015.2456249.

PMID:
26414787
17.

Modeling the pharyngeal pressure during adult nasal high flow therapy.

Kumar H, Spence CJ, Tawhai MH.

Respir Physiol Neurobiol. 2015 Dec;219:51-7. doi: 10.1016/j.resp.2015.06.011. Epub 2015 Jul 18.

PMID:
26197246
18.

A Numerical Study of Water Loss Rate Distributions in MDCT-Based Human Airway Models.

Wu D, Miyawaki S, Tawhai MH, Hoffman EA, Lin CL.

Ann Biomed Eng. 2015 Nov;43(11):2708-21. doi: 10.1007/s10439-015-1318-3. Epub 2015 Apr 14.

19.

Comparison of generic and subject-specific models for simulation of pulmonary perfusion and forced expiration.

Hedges KL, Clark AR, Tawhai MH.

Interface Focus. 2015 Apr 6;5(2):20140090. doi: 10.1098/rsfs.2014.0090.

20.

Multiscale modelling of the feto-placental vasculature.

Clark AR, Lin M, Tawhai M, Saghian R, James JL.

Interface Focus. 2015 Apr 6;5(2):20140078. doi: 10.1098/rsfs.2014.0078.

21.

Quantifying normal geometric variation in human pulmonary lobar geometry from high resolution computed tomography.

Chan HF, Clark AR, Hoffman EA, Malcolm DT, Tawhai MH.

J Biomech Eng. 2015 May;137(5):051010. doi: 10.1115/1.4029919. Epub 2015 Mar 18.

22.

Dynamic blood flow and wall shear stress in pulmonary hypertensive disease.

Postles A, Clark AR, Tawhai MH.

Conf Proc IEEE Eng Med Biol Soc. 2014;2014:5671-4. doi: 10.1109/EMBC.2014.6944914.

PMID:
25571282
23.

Supine to upright lung mechanics: do changes in lung shape influence lung tissue deformation?

Chan HF, Tawhai MH, Levin DL, Bartholmai BB, Clark AR.

Conf Proc IEEE Eng Med Biol Soc. 2014;2014:832-5. doi: 10.1109/EMBC.2014.6943720.

PMID:
25570088
24.

The effect of gas exchange on multiple-breath nitrogen washout measures of ventilation inhomogeneity in the mouse.

Dharmakumara M, Prisk GK, Royce SG, Tawhai M, Thompson BR.

J Appl Physiol (1985). 2014 Nov 1;117(9):1049-54. doi: 10.1152/japplphysiol.00543.2014. Epub 2014 Sep 11.

25.

A numerical study of heat and water vapor transfer in MDCT-based human airway models.

Wu D, Tawhai MH, Hoffman EA, Lin CL.

Ann Biomed Eng. 2014 Oct;42(10):2117-31. doi: 10.1007/s10439-014-1074-9. Epub 2014 Aug 1.

26.

Hypoxic pulmonary vasoconstriction as a contributor to response in acute pulmonary embolism.

Burrowes KS, Clark AR, Wilsher ML, Milne DG, Tawhai MH.

Ann Biomed Eng. 2014 Aug;42(8):1631-43. doi: 10.1007/s10439-014-1011-y. Epub 2014 Apr 26.

PMID:
24770844
27.

Integrative approaches for modeling regulation and function of the respiratory system.

Ben-Tal A, Tawhai MH.

Wiley Interdiscip Rev Syst Biol Med. 2013 Nov-Dec;5(6):687-99. doi: 10.1002/wsbm.1244. Epub 2013 Sep 9. Review.

28.

Lack of functional information explains the poor performance of 'clot load scores' at predicting outcome in acute pulmonary embolism.

Clark AR, Milne D, Wilsher M, Burrowes KS, Bajaj M, Tawhai MH.

Respir Physiol Neurobiol. 2014 Jan 1;190:1-13. doi: 10.1016/j.resp.2013.09.005. Epub 2013 Sep 27.

PMID:
24080246
29.

Blood flow in capillaries of the human lung.

Haber S, Clark A, Tawhai M.

J Biomech Eng. 2013 Oct 1;135(10):101006-11. doi: 10.1115/1.4025092.

PMID:
23897065
30.

Multiscale image-based modeling and simulation of gas flow and particle transport in the human lungs.

Lin CL, Tawhai MH, Hoffman EA.

Wiley Interdiscip Rev Syst Biol Med. 2013 Sep-Oct;5(5):643-55. doi: 10.1002/wsbm.1234. Epub 2013 Jul 10. Review.

31.

Physiology's impact: discovering life.

Sieck GC, Mantilla C, Tawhai M.

Physiology (Bethesda). 2013 Jul;28(4):212-3. doi: 10.1152/physiol.00027.2013. No abstract available.

32.

A multiscale MDCT image-based breathing lung model with time-varying regional ventilation.

Yin Y, Choi J, Hoffman EA, Tawhai MH, Lin CL.

J Comput Phys. 2013 Jul 1;244:168-192.

33.

Registration-based assessment of regional lung function via volumetric CT images of normal subjects vs. severe asthmatics.

Choi S, Hoffman EA, Wenzel SE, Tawhai MH, Yin Y, Castro M, Lin CL.

J Appl Physiol (1985). 2013 Sep 1;115(5):730-42. doi: 10.1152/japplphysiol.00113.2013. Epub 2013 Jun 6.

34.

MDCT-based quantification of porcine pulmonary arterial morphometry and self-similarity of arterial branching geometry.

Lee YC, Clark AR, Fuld MK, Haynes S, Divekar AA, Hoffman EA, Tawhai MH.

J Appl Physiol (1985). 2013 May;114(9):1191-201. doi: 10.1152/japplphysiol.00868.2012. Epub 2013 Feb 28.

35.

Multiscale imaging and registration-driven model for pulmonary acinar mechanics in the mouse.

Kumar H, Vasilescu DM, Yin Y, Hoffman EA, Tawhai MH, Lin CL.

J Appl Physiol (1985). 2013 Apr;114(8):971-8. doi: 10.1152/japplphysiol.01136.2012. Epub 2013 Feb 14.

36.

Ventilatory and cardiac responses to pulmonary embolism: consequences for gas exchange and blood pressure.

Clark AR, Bajaj M, Wilsher ML, Milne DG, Tawhai MH.

Conf Proc IEEE Eng Med Biol Soc. 2012;2012:6657-60. doi: 10.1109/EMBC.2012.6347521.

PMID:
23367456
37.

An in-vivo computed tomography approach for quantifying porcine pulmonary arterial morphometry.

Lee YC, Clark A, Fuld M, Haynes S, Divekar A, Hoffman E, Tawhai M.

Conf Proc IEEE Eng Med Biol Soc. 2012;2012:5400-3. doi: 10.1109/EMBC.2012.6347215.

PMID:
23367150
38.

Quantifying tissue heterogeneity using quadtree decomposition.

Subramaniam K, Hoffman EA, Tawhai MH.

Conf Proc IEEE Eng Med Biol Soc. 2012;2012:4079-82. doi: 10.1109/EMBC.2012.6346863.

PMID:
23366824
39.

The importance of synergy between deep inspirations and fluidization in reversing airway closure.

Donovan GM, Sneyd J, Tawhai MH.

PLoS One. 2012;7(11):e48552. doi: 10.1371/journal.pone.0048552. Epub 2012 Nov 8.

40.

Optimal graph search based segmentation of airway tree double surfaces across bifurcations.

Liu X, Chen DZ, Tawhai MH, Wu X, Hoffman EA, Sonka M.

IEEE Trans Med Imaging. 2013 Mar;32(3):493-510. doi: 10.1109/TMI.2012.2223760. Epub 2012 Oct 10.

41.

Relating indices of inert gas washout to localised bronchoconstriction.

Mitchell JH, Hoffman EA, Tawhai MH.

Respir Physiol Neurobiol. 2012 Sep 30;183(3):224-33. doi: 10.1016/j.resp.2012.06.031. Epub 2012 Jul 5. Erratum in: Respir Physiol Neurobiol. 2013 Feb 1;185(3):665.

42.

Quantifying parenchymal tethering in a finite element simulation of a human lung slice under bronchoconstriction.

Breen BJ, Donovan GM, Sneyd J, Tawhai MH.

Respir Physiol Neurobiol. 2012 Aug 15;183(2):85-90. doi: 10.1016/j.resp.2012.06.014. Epub 2012 Jun 23.

43.

A multi-scale approach to airway hyperresponsiveness: from molecule to organ.

Lauzon AM, Bates JH, Donovan G, Tawhai M, Sneyd J, Sanderson MJ.

Front Physiol. 2012 Jun 11;3:191. doi: 10.3389/fphys.2012.00191. eCollection 2012.

44.

Arteries dominate volume changes during brief functional hyperemia: evidence from mathematical modelling.

Barrett MJ, Tawhai MH, Suresh V.

Neuroimage. 2012 Aug 1;62(1):482-92. doi: 10.1016/j.neuroimage.2012.05.005. Epub 2012 May 12.

PMID:
22587899
45.

What can imaging tell us about physiology? Lung growth and regional mechanical strain.

Hsia CC, Tawhai MH.

J Appl Physiol (1985). 2012 Sep;113(6):937-46. doi: 10.1152/japplphysiol.00289.2012. Epub 2012 May 10. Review.

46.

A computational model of the topographic distribution of ventilation in healthy human lungs.

Swan AJ, Clark AR, Tawhai MH.

J Theor Biol. 2012 May 7;300:222-31. doi: 10.1016/j.jtbi.2012.01.042. Epub 2012 Feb 5.

47.

Effect of carrier gas properties on aerosol distribution in a CT-based human airway numerical model.

Miyawaki S, Tawhai MH, Hoffman EA, Lin CL.

Ann Biomed Eng. 2012 Jul;40(7):1495-507. doi: 10.1007/s10439-011-0503-2. Epub 2012 Jan 14.

48.

Blood flow redistribution and ventilation-perfusion mismatch during embolic pulmonary arterial occlusion.

Burrowes KS, Clark AR, Tawhai MH.

Pulm Circ. 2011 Jul-Sep;1(3):365-76. doi: 10.4103/2045-8932.87302.

49.

Computational models of the pulmonary circulation: Insights and the move towards clinically directed studies.

Tawhai MH, Clark AR, Burrowes KS.

Pulm Circ. 2011 Apr-Jun;1(2):224-38. doi: 10.4103/2045-8932.83452.

50.

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