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Items: 34


Balancing dual demands on the physician-scientist workforce.

Martin DM, Rathmell WK, Tavazoie SF.

J Clin Invest. 2018 Aug 1;128(8):3204-3205. doi: 10.1172/JCI122099. Epub 2018 Jul 16. No abstract available.


LXR/ApoE Activation Restricts Innate Immune Suppression in Cancer.

Tavazoie MF, Pollack I, Tanqueco R, Ostendorf BN, Reis BS, Gonsalves FC, Kurth I, Andreu-Agullo C, Derbyshire ML, Posada J, Takeda S, Tafreshian KN, Rowinsky E, Szarek M, Waltzman RJ, Mcmillan EA, Zhao C, Mita M, Mita A, Chmielowski B, Postow MA, Ribas A, Mucida D, Tavazoie SF.

Cell. 2018 Feb 8;172(4):825-840.e18. doi: 10.1016/j.cell.2017.12.026. Epub 2018 Jan 11.


MicroRNA-203 predicts human survival after resection of colorectal liver metastasis.

Kingham TP, Nguyen HCB, Zheng J, Konstantinidis IT, Sadot E, Shia J, Kuk D, Zhang S, Saltz L, D'Angelica MI, Jarnagin WR, Goodarzi H, Tavazoie SF.

Oncotarget. 2017 Mar 21;8(12):18821-18831. doi: 10.18632/oncotarget.13816.


Cancer: Endothelial-cell killing promotes metastasis.

Alarcón CR, Tavazoie SF.

Nature. 2016 Aug 11;536(7615):154-5. Epub 2016 Aug 3. No abstract available.


TMEM2 Is a SOX4-Regulated Gene That Mediates Metastatic Migration and Invasion in Breast Cancer.

Lee H, Goodarzi H, Tavazoie SF, Alarcón CR.

Cancer Res. 2016 Sep 1;76(17):4994-5005. doi: 10.1158/0008-5472.CAN-15-2322. Epub 2016 Jun 21.


Modulated Expression of Specific tRNAs Drives Gene Expression and Cancer Progression.

Goodarzi H, Nguyen HCB, Zhang S, Dill BD, Molina H, Tavazoie SF.

Cell. 2016 Jun 2;165(6):1416-1427. doi: 10.1016/j.cell.2016.05.046.


Highly variable cancer subpopulations that exhibit enhanced transcriptome variability and metastatic fitness.

Nguyen A, Yoshida M, Goodarzi H, Tavazoie SF.

Nat Commun. 2016 May 3;7:11246. doi: 10.1038/ncomms11246.


PITPNC1 Recruits RAB1B to the Golgi Network to Drive Malignant Secretion.

Halberg N, Sengelaub CA, Navrazhina K, Molina H, Uryu K, Tavazoie SF.

Cancer Cell. 2016 Mar 14;29(3):339-353. doi: 10.1016/j.ccell.2016.02.013.


Muscleblind-like 1 suppresses breast cancer metastatic colonization and stabilizes metastasis suppressor transcripts.

Fish L, Pencheva N, Goodarzi H, Tran H, Yoshida M, Tavazoie SF.

Genes Dev. 2016 Feb 15;30(4):386-98. doi: 10.1101/gad.270645.115.


PKLR promotes colorectal cancer liver colonization through induction of glutathione synthesis.

Nguyen A, Loo JM, Mital R, Weinberg EM, Man FY, Zeng Z, Paty PB, Saltz L, Janjigian YY, de Stanchina E, Tavazoie SF.

J Clin Invest. 2016 Feb;126(2):681-94. doi: 10.1172/JCI83587. Epub 2016 Jan 19.


PTPRN2 and PLCβ1 promote metastatic breast cancer cell migration through PI(4,5)P2-dependent actin remodeling.

Sengelaub CA, Navrazhina K, Ross JB, Halberg N, Tavazoie SF.

EMBO J. 2016 Jan 4;35(1):62-76. doi: 10.15252/embj.201591973. Epub 2015 Nov 30.


HNRNPA2B1 Is a Mediator of m(6)A-Dependent Nuclear RNA Processing Events.

Alarcón CR, Goodarzi H, Lee H, Liu X, Tavazoie S, Tavazoie SF.

Cell. 2015 Sep 10;162(6):1299-308. doi: 10.1016/j.cell.2015.08.011. Epub 2015 Aug 27.


Mechanosensitive pannexin-1 channels mediate microvascular metastatic cell survival.

Furlow PW, Zhang S, Soong TD, Halberg N, Goodarzi H, Mangrum C, Wu YG, Elemento O, Tavazoie SF.

Nat Cell Biol. 2015 Jul;17(7):943-52. doi: 10.1038/ncb3194. Epub 2015 Jun 22.


Endogenous tRNA-Derived Fragments Suppress Breast Cancer Progression via YBX1 Displacement.

Goodarzi H, Liu X, Nguyen HC, Zhang S, Fish L, Tavazoie SF.

Cell. 2015 May 7;161(4):790-802. doi: 10.1016/j.cell.2015.02.053.


Identification of molecular determinants of primary and metastatic tumour re-initiation in breast cancer.

Ross JB, Huh D, Noble LB, Tavazoie SF.

Nat Cell Biol. 2015 May;17(5):651-64. doi: 10.1038/ncb3148. Epub 2015 Apr 13.


N6-methyladenosine marks primary microRNAs for processing.

Alarcón CR, Lee H, Goodarzi H, Halberg N, Tavazoie SF.

Nature. 2015 Mar 26;519(7544):482-5. doi: 10.1038/nature14281. Epub 2015 Mar 18.


Extracellular metabolic energetics can promote cancer progression.

Loo JM, Scherl A, Nguyen A, Man FY, Weinberg E, Zeng Z, Saltz L, Paty PB, Tavazoie SF.

Cell. 2015 Jan 29;160(3):393-406. doi: 10.1016/j.cell.2014.12.018. Epub 2015 Jan 15.


TARBP2 binding structured RNA elements drives metastasis.

Goodarzi H, Tavazoie SF, Tavazoie S.

Cell Cycle. 2014;13(18):2799-800. doi: 10.4161/15384101.2014.954453. No abstract available.


Metastasis-suppressor transcript destabilization through TARBP2 binding of mRNA hairpins.

Goodarzi H, Zhang S, Buss CG, Fish L, Tavazoie S, Tavazoie SF.

Nature. 2014 Sep 11;513(7517):256-60. doi: 10.1038/nature13466. Epub 2014 Jul 9.


Broad-spectrum therapeutic suppression of metastatic melanoma through nuclear hormone receptor activation.

Pencheva N, Buss CG, Posada J, Merghoub T, Tavazoie SF.

Cell. 2014 Feb 27;156(5):986-1001. doi: 10.1016/j.cell.2014.01.038.


Cardiorespiratory response to exercise on a large therapeutic roll.

Gappmaier E, Tavazoie SF, Jacketta MG.

Cardiopulm Phys Ther J. 2013 Sep;24(3):5-13.


Control of metastatic progression by microRNA regulatory networks.

Pencheva N, Tavazoie SF.

Nat Cell Biol. 2013 Jun;15(6):546-54. doi: 10.1038/ncb2769. Review.


Convergent multi-miRNA targeting of ApoE drives LRP1/LRP8-dependent melanoma metastasis and angiogenesis.

Pencheva N, Tran H, Buss C, Huh D, Drobnjak M, Busam K, Tavazoie SF.

Cell. 2012 Nov 21;151(5):1068-82. doi: 10.1016/j.cell.2012.10.028. Epub 2012 Nov 8.


microRNA regulation of cancer-endothelial interactions: vesicular microRNAs on the move….

Halberg N, Alarcón C, Tavazoie SF.

EMBO J. 2012 Aug 29;31(17):3509-10. doi: 10.1038/emboj.2012.198. Epub 2012 Jul 24. No abstract available.


A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells.

Png KJ, Halberg N, Yoshida M, Tavazoie SF.

Nature. 2011 Dec 14;481(7380):190-4. doi: 10.1038/nature10661.


Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs.

Oskarsson T, Acharyya S, Zhang XH, Vanharanta S, Tavazoie SF, Morris PG, Downey RJ, Manova-Todorova K, Brogi E, Massagué J.

Nat Med. 2011 Jun 26;17(7):867-74. doi: 10.1038/nm.2379.


MicroRNA-335 inhibits tumor reinitiation and is silenced through genetic and epigenetic mechanisms in human breast cancer.

Png KJ, Yoshida M, Zhang XH, Shu W, Lee H, Rimner A, Chan TA, Comen E, Andrade VP, Kim SW, King TA, Hudis CA, Norton L, Hicks J, Massagué J, Tavazoie SF.

Genes Dev. 2011 Feb 1;25(3):226-31. doi: 10.1101/gad.1974211.


Endogenous human microRNAs that suppress breast cancer metastasis.

Tavazoie SF, Alarcón C, Oskarsson T, Padua D, Wang Q, Bos PD, Gerald WL, Massagué J.

Nature. 2008 Jan 10;451(7175):147-52. doi: 10.1038/nature06487.


Regulation of neuronal morphology and function by the tumor suppressors Tsc1 and Tsc2.

Tavazoie SF, Alvarez VA, Ridenour DA, Kwiatkowski DJ, Sabatini BL.

Nat Neurosci. 2005 Dec;8(12):1727-34. Epub 2005 Nov 6.


Coexistence of widespread clones and large radial clones in early embryonic ferret cortex.

Ware ML, Tavazoie SF, Reid CB, Walsh CA.

Cereb Cortex. 1999 Sep;9(6):636-45.


CREB: a major mediator of neuronal neurotrophin responses.

Finkbeiner S, Tavazoie SF, Maloratsky A, Jacobs KM, Harris KM, Greenberg ME.

Neuron. 1997 Nov;19(5):1031-47.


Clonal dispersion and evidence for asymmetric cell division in ferret cortex.

Reid CB, Tavazoie SF, Walsh CA.

Development. 1997 Jun;124(12):2441-50.


Differential block of nicotinic synapses on B versus C neurones in sympathetic ganglia of frog by alpha-conotoxins MII and ImI.

Tavazoie SF, Tavazoie MF, McIntosh JM, Olivera BM, Yoshikami D.

Br J Pharmacol. 1997 Mar;120(6):995-1000.

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