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Items: 1 to 50 of 75

1.

Columbia Open Health Data, clinical concept prevalence and co-occurrence from electronic health records.

Ta CN, Dumontier M, Hripcsak G, Tatonetti NP, Weng C.

Sci Data. 2018 Nov 27;5:180273. doi: 10.1038/sdata.2018.273.

2.

Pharmacological risk factors associated with hospital readmission rates in a psychiatric cohort identified using prescriptome data mining.

Shameer K, Perez-Rodriguez MM, Bachar R, Li L, Johnson A, Johnson KW, Glicksberg BS, Smith MR, Readhead B, Scarpa J, Jebakaran J, Kovatch P, Lim S, Goodman W, Reich DL, Kasarskis A, Tatonetti NP, Dudley JT.

BMC Med Inform Decis Mak. 2018 Sep 14;18(Suppl 3):79. doi: 10.1186/s12911-018-0653-3.

3.

Structural and Functional Cardiac Profile after Prolonged Duration of Mechanical Unloading: Potential Implications for Myocardial Recovery.

Castillero E, Ali ZA, Akashi H, Giangreco N, Wang C, Stöhr EJ, Ji R, Zhang X, Kheysin N, Park JS, Hegde S, Patel S, Stein S, Cuenca C, Leung D, Homma S, Tatonetti NP, Topkara V, Takeda K, Colombo PC, Naka Y, Sweeney HL, Schulze PC, George I.

Am J Physiol Heart Circ Physiol. 2018 Aug 24. doi: 10.1152/ajpheart.00187.2018. [Epub ahead of print]

PMID:
30141986
4.

Pathogen population structure can explain hospital outbreaks.

Spagnolo F, Cristofari P, Tatonetti NP, Ginzburg LR, Dykhuizen DE.

ISME J. 2018 Dec;12(12):2835-2843. doi: 10.1038/s41396-018-0235-5. Epub 2018 Jul 25.

PMID:
30046167
5.

Tissue-Specific Analysis of Pharmacological Pathways.

Hao Y, Quinnies K, Realubit R, Karan C, Tatonetti NP.

CPT Pharmacometrics Syst Pharmacol. 2018 Jul;7(7):453-463. doi: 10.1002/psp4.12305. Epub 2018 Jun 19.

6.

Disease Heritability Inferred from Familial Relationships Reported in Medical Records.

Polubriaginof FCG, Vanguri R, Quinnies K, Belbin GM, Yahi A, Salmasian H, Lorberbaum T, Nwankwo V, Li L, Shervey MM, Glowe P, Ionita-Laza I, Simmerling M, Hripcsak G, Bakken S, Goldstein D, Kiryluk K, Kenny EE, Dudley J, Vawdrey DK, Tatonetti NP.

Cell. 2018 Jun 14;173(7):1692-1704.e11. doi: 10.1016/j.cell.2018.04.032. Epub 2018 May 17.

PMID:
29779949
7.
8.

Translational medicine in the Age of Big Data.

Tatonetti NP.

Brief Bioinform. 2017 Oct 12. doi: 10.1093/bib/bbx116. [Epub ahead of print]

PMID:
29040418
9.

Uncovering exposures responsible for birth season - disease effects: a global study.

Boland MR, Parhi P, Li L, Miotto R, Carroll R, Iqbal U, Nguyen PA, Schuemie M, You SC, Smith D, Mooney S, Ryan P, Li YJ, Park RW, Denny J, Dudley JT, Hripcsak G, Gentine P, Tatonetti NP.

J Am Med Inform Assoc. 2017 Sep 28. doi: 10.1093/jamia/ocx105. [Epub ahead of print]

PMID:
29036387
10.

Development of A Machine Learning Algorithm to Classify Drugs Of Unknown Fetal Effect.

Boland MR, Polubriaginof F, Tatonetti NP.

Sci Rep. 2017 Oct 9;7(1):12839. doi: 10.1038/s41598-017-12943-x.

11.

Machine learning: novel bioinformatics approaches for combating antimicrobial resistance.

Macesic N, Polubriaginof F, Tatonetti NP.

Curr Opin Infect Dis. 2017 Dec;30(6):511-517. doi: 10.1097/QCO.0000000000000406. Review.

PMID:
28914640
12.

Climate Classification is an Important Factor in Assessing Quality-of-Care Across Hospitals.

Boland MR, Parhi P, Gentine P, Tatonetti NP.

Sci Rep. 2017 Jul 10;7(1):4948. doi: 10.1038/s41598-017-04708-3.

13.

Reply: Combination Therapy With Ceftriaxone and Lansoprazole, Acquired Long QT Syndrome and Torsades de Pointes Risk.

Lorberbaum T, Tatonetti NP.

J Am Coll Cardiol. 2017 Apr 11;69(14):1877-1878. doi: 10.1016/j.jacc.2016.12.042. No abstract available.

14.

Ten Simple Rules to Enable Multi-site Collaborations through Data Sharing.

Boland MR, Karczewski KJ, Tatonetti NP.

PLoS Comput Biol. 2017 Jan 19;13(1):e1005278. doi: 10.1371/journal.pcbi.1005278. eCollection 2017 Jan. No abstract available.

15.

METHODS TO ENHANCE THE REPRODUCIBILITY OF PRECISION MEDICINE.

Manrai AK, Patel CJ, Gehlenborg N, Tatonetti NP, Ioannidis JP, Kohane IS.

Pac Symp Biocomput. 2016;21:180-182. No abstract available.

16.

PREDICTIVE MODELING OF HOSPITAL READMISSION RATES USING ELECTRONIC MEDICAL RECORD-WIDE MACHINE LEARNING: A CASE-STUDY USING MOUNT SINAI HEART FAILURE COHORT.

Shameer K, Johnson KW, Yahi A, Miotto R, Li LI, Ricks D, Jebakaran J, Kovatch P, Sengupta PP, Gelijns S, Moskovitz A, Darrow B, David DL, Kasarskis A, Tatonetti NP, Pinney S, Dudley JT.

Pac Symp Biocomput. 2017;22:276-287. doi: 10.1142/9789813207813_0027.

17.

METHODS TO ENSURE THE REPRODUCIBILITY OF BIOMEDICAL RESEARCH.

Karczewski KJ, Tatonetti NP, Manrai AK, Patel CJ, Titus Brown C, Ioannidis JPA.

Pac Symp Biocomput. 2017;22:117-119. doi: 10.1142/9789813207813_0012.

18.

Silencing c-Myc translation as a therapeutic strategy through targeting PI3Kδ and CK1ε in hematological malignancies.

Deng C, Lipstein MR, Scotto L, Jirau Serrano XO, Mangone MA, Li S, Vendome J, Hao Y, Xu X, Deng SX, Realubit RB, Tatonetti NP, Karan C, Lentzsch S, Fruman DA, Honig B, Landry DW, O'Connor OA.

Blood. 2017 Jan 5;129(1):88-99. doi: 10.1182/blood-2016-08-731240. Epub 2016 Oct 26.

19.

Coupling Data Mining and Laboratory Experiments to Discover Drug Interactions Causing QT Prolongation.

Lorberbaum T, Sampson KJ, Chang JB, Iyer V, Woosley RL, Kass RS, Tatonetti NP.

J Am Coll Cardiol. 2016 Oct 18;68(16):1756-1764. doi: 10.1016/j.jacc.2016.07.761.

20.

Replicating Cardiovascular Condition-Birth Month Associations.

Li L, Boland MR, Miotto R, Tatonetti NP, Dudley JT.

Sci Rep. 2016 Sep 14;6:33166. doi: 10.1038/srep33166.

21.

Using a Novel Ontology to Inform the Discovery of Therapeutic Peptides from Animal Venoms.

Romano JD, Tatonetti NP.

AMIA Jt Summits Transl Sci Proc. 2016 Jul 20;2016:209-18. eCollection 2016.

22.

In Search of 'Birth Month Genes': Using Existing Data Repositories to Locate Genes Underlying Birth Month-Disease Relationships.

Boland MR, Tatonetti NP.

AMIA Jt Summits Transl Sci Proc. 2016 Jul 20;2016:189-98. eCollection 2016.

23.

Predicting G protein-coupled receptor downstream signaling by tissue expression.

Hao Y, Tatonetti NP.

Bioinformatics. 2016 Nov 15;32(22):3435-3443. Epub 2016 Aug 2.

24.

A novel, rapid method to compare the therapeutic windows of oral anticoagulants using the Hill coefficient.

Chang JB, Quinnies KM, Realubit R, Karan C, Rand JH, Tatonetti NP.

Sci Rep. 2016 Jul 21;6:29387. doi: 10.1038/srep29387.

25.

Investigation of 7-dehydrocholesterol reductase pathway to elucidate off-target prenatal effects of pharmaceuticals: a systematic review.

Boland MR, Tatonetti NP.

Pharmacogenomics J. 2016 Oct;16(5):411-29. doi: 10.1038/tpj.2016.48. Epub 2016 Jul 12. Review.

26.

A Computational Drug Repositioning Approach for Targeting Oncogenic Transcription Factors.

Gayvert KM, Dardenne E, Cheung C, Boland MR, Lorberbaum T, Wanjala J, Chen Y, Rubin MA, Tatonetti NP, Rickman DS, Elemento O.

Cell Rep. 2016 Jun 14;15(11):2348-56. doi: 10.1016/j.celrep.2016.05.037. Epub 2016 Jun 2.

27.

A curated and standardized adverse drug event resource to accelerate drug safety research.

Banda JM, Evans L, Vanguri RS, Tatonetti NP, Ryan PB, Shah NH.

Sci Data. 2016 May 10;3:160026. doi: 10.1038/sdata.2016.26.

28.

Improving condition severity classification with an efficient active learning based framework.

Nissim N, Boland MR, Tatonetti NP, Elovici Y, Hripcsak G, Shahar Y, Moskovitch R.

J Biomed Inform. 2016 Jun;61:44-54. doi: 10.1016/j.jbi.2016.03.016. Epub 2016 Mar 22.

29.

A Pharmacovigilance Signaling System Based on FDA Regulatory Action and Post-Marketing Adverse Event Reports.

Hoffman KB, Dimbil M, Tatonetti NP, Kyle RF.

Drug Saf. 2016 Jun;39(6):561-75. doi: 10.1007/s40264-016-0409-x.

PMID:
26946292
30.

An Integrative Data Science Pipeline to Identify Novel Drug Interactions that Prolong the QT Interval.

Lorberbaum T, Sampson KJ, Woosley RL, Kass RS, Tatonetti NP.

Drug Saf. 2016 May;39(5):433-41. doi: 10.1007/s40264-016-0393-1.

31.

A Drug Safety Rating System Based on Postmarketing Costs Associated with Adverse Events and Patient Outcomes.

Hoffman KB, Dimbil M, Kyle RF, Tatonetti NP, Erdman CB, Demakas A, Chen D, Overstreet BM.

J Manag Care Spec Pharm. 2015 Dec;21(12):1134-43.

32.

Mapping the effects of drugs on the immune system.

Kidd BA, Wroblewska A, Boland MR, Agudo J, Merad M, Tatonetti NP, Brown BD, Dudley JT.

Nat Biotechnol. 2016 Jan;34(1):47-54. doi: 10.1038/nbt.3367. Epub 2015 Nov 30.

33.

VenomKB, a new knowledge base for facilitating the validation of putative venom therapies.

Romano JD, Tatonetti NP.

Sci Data. 2015 Nov 24;2:150065. doi: 10.1038/sdata.2015.65.

34.

Systems biology approaches for identifying adverse drug reactions and elucidating their underlying biological mechanisms.

Boland MR, Jacunski A, Lorberbaum T, Romano JD, Moskovitch R, Tatonetti NP.

Wiley Interdiscip Rev Syst Biol Med. 2016 Mar-Apr;8(2):104-22. doi: 10.1002/wsbm.1323. Epub 2015 Nov 12. Review.

35.

Connectivity Homology Enables Inter-Species Network Models of Synthetic Lethality.

Jacunski A, Dixon SJ, Tatonetti NP.

PLoS Comput Biol. 2015 Oct 9;11(10):e1004506. doi: 10.1371/journal.pcbi.1004506. eCollection 2015 Oct.

36.

Are All Vaccines Created Equal? Using Electronic Health Records to Discover Vaccines Associated With Clinician-Coded Adverse Events.

Boland MR, Tatonetti NP.

AMIA Jt Summits Transl Sci Proc. 2015 Mar 23;2015:196-200. eCollection 2015.

37.

A knowledge-based, automated method for phenotyping in the EHR using only clinical pathology reports.

Yahi A, Tatonetti NP.

AMIA Jt Summits Transl Sci Proc. 2015 Mar 23;2015:64-8. eCollection 2015.

38.

Improving Detection of Arrhythmia Drug-Drug Interactions in Pharmacovigilance Data through the Implementation of Similarity-Based Modeling.

Vilar S, Lorberbaum T, Hripcsak G, Tatonetti NP.

PLoS One. 2015 Jun 12;10(6):e0129974. doi: 10.1371/journal.pone.0129974. eCollection 2015.

39.

Birth month affects lifetime disease risk: a phenome-wide method.

Boland MR, Shahn Z, Madigan D, Hripcsak G, Tatonetti NP.

J Am Med Inform Assoc. 2015 Sep;22(5):1042-53. doi: 10.1093/jamia/ocv046. Epub 2015 Jun 2.

40.

Toward a complete dataset of drug-drug interaction information from publicly available sources.

Ayvaz S, Horn J, Hassanzadeh O, Zhu Q, Stan J, Tatonetti NP, Vilar S, Brochhausen M, Samwald M, Rastegar-Mojarad M, Dumontier M, Boyce RD.

J Biomed Inform. 2015 Jun;55:206-17. doi: 10.1016/j.jbi.2015.04.006. Epub 2015 Apr 24.

41.

Development and validation of a classification approach for extracting severity automatically from electronic health records.

Boland MR, Tatonetti NP, Hripcsak G.

J Biomed Semantics. 2015 Apr 6;6:14. doi: 10.1186/s13326-015-0010-8. eCollection 2015.

42.

3D pharmacophoric similarity improves multi adverse drug event identification in pharmacovigilance.

Vilar S, Tatonetti NP, Hripcsak G.

Sci Rep. 2015 Mar 6;5:8809. doi: 10.1038/srep08809.

43.

Systems pharmacology augments drug safety surveillance.

Lorberbaum T, Nasir M, Keiser MJ, Vilar S, Hripcsak G, Tatonetti NP.

Clin Pharmacol Ther. 2015 Feb;97(2):151-8. doi: 10.1002/cpt.2. Epub 2014 Dec 20.

44.

An Assessment of Family History Information Captured in an Electronic Health Record.

Polubriaginof F, Tatonetti NP, Vawdrey DK.

AMIA Annu Symp Proc. 2015 Nov 5;2015:2035-42. eCollection 2015.

45.

State of the art and development of a drug-drug interaction large scale predictor based on 3D pharmacophoric similarity.

Vilar S, Uriarte E, Santana L, Friedman C, Tatonetti NP.

Curr Drug Metab. 2014;15(5):490-501.

PMID:
25431152
46.

Stimulated reporting: the impact of US food and drug administration-issued alerts on the adverse event reporting system (FAERS).

Hoffman KB, Demakas AR, Dimbil M, Tatonetti NP, Erdman CB.

Drug Saf. 2014 Nov;37(11):971-80. doi: 10.1007/s40264-014-0225-0.

47.

Similarity-based modeling applied to signal detection in pharmacovigilance.

Vilar S, Ryan PB, Madigan D, Stang PE, Schuemie MJ, Friedman C, Tatonetti NP, Hripcsak G.

CPT Pharmacometrics Syst Pharmacol. 2014 Sep 24;3:e137. doi: 10.1038/psp.2014.35.

48.

Similarity-based modeling in large-scale prediction of drug-drug interactions.

Vilar S, Uriarte E, Santana L, Lorberbaum T, Hripcsak G, Friedman C, Tatonetti NP.

Nat Protoc. 2014 Sep;9(9):2147-63. doi: 10.1038/nprot.2014.151. Epub 2014 Aug 14.

49.

Insight into the interactions between novel coumarin derivatives and human A3 adenosine receptors.

Matos MJ, Vilar S, Kachler S, Fonseca A, Santana L, Uriarte E, Borges F, Tatonetti NP, Klotz KN.

ChemMedChem. 2014 Oct;9(10):2245-53. doi: 10.1002/cmdc.201402205. Epub 2014 Jul 18.

PMID:
25044491
50.

Bridging islands of information to establish an integrated knowledge base of drugs and health outcomes of interest.

Boyce RD, Ryan PB, Norén GN, Schuemie MJ, Reich C, Duke J, Tatonetti NP, Trifirò G, Harpaz R, Overhage JM, Hartzema AG, Khayter M, Voss EA, Lambert CG, Huser V, Dumontier M.

Drug Saf. 2014 Aug;37(8):557-67. doi: 10.1007/s40264-014-0189-0.

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