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Items: 1 to 50 of 277

1.

The β2-adrenergic receptor is a molecular switch for neuroendocrine transdifferentiation of prostate cancer cells.

Braadland PR, Ramberg H, Grytli HH, Urbanucci A, Nielsen HK, Guldvik IJ, Engedal A, Ketola K, Wang W, Svindland A, Mills IG, Bjartell A, Tasken KA.

Mol Cancer Res. 2019 Aug 8. pii: molcanres.0605.2018. doi: 10.1158/1541-7786.MCR-18-0605. [Epub ahead of print]

PMID:
31395667
2.

Low Expression of miR-424-3p is Highly Correlated with Clinical Failure in Prostate Cancer.

Richardsen E, Andersen S, Al-Saad S, Rakaee M, Nordby Y, Pedersen MI, Ness N, Ingebriktsen LM, Fassina A, Taskén KA, Mills IG, Donnem T, Bremnes RM, Busund LT.

Sci Rep. 2019 Jul 23;9(1):10662. doi: 10.1038/s41598-019-47234-0.

3.

Carboxyl-Terminal Src Kinase Binds CD28 upon Activation and Mutes Downstream Signaling.

Skånland SS, Taskén K.

J Immunol. 2019 Aug 15;203(4):1055-1063. doi: 10.4049/jimmunol.1801660. Epub 2019 Jul 10.

PMID:
31292214
4.

Correction: Ezrin-anchored PKA phosphorylates serine 369 and 373 on connexin 43 to enhance gap junction assembly, communication, and cell fusion.

Dukic AR, Gerbaud P, Guibourdenche J, Thiede B, Taskén K, Pidoux G.

Biochem J. 2019 Jul 2;476(13):1927. doi: 10.1042/BCJ-2017-0529_COR. No abstract available.

PMID:
31266855
5.

Prognostic biomarkers for immunotherapy with ipilimumab in metastatic melanoma.

Nyakas M, Aamdal E, Jacobsen KD, Guren TK, Aamdal S, Hagene KT, Brunsvig P, Yndestad A, Halvorsen B, Tasken KA, Aukrust P, Maelandsmo GM, Ueland T.

Clin Exp Immunol. 2019 Jul;197(1):74-82. doi: 10.1111/cei.13283. Epub 2019 Mar 21.

6.

Remodeling of secretory lysosomes during education tunes functional potential in NK cells.

Goodridge JP, Jacobs B, Saetersmoen ML, Clement D, Hammer Q, Clancy T, Skarpen E, Brech A, Landskron J, Grimm C, Pfefferle A, Meza-Zepeda L, Lorenz S, Wiiger MT, Louch WE, Ask EH, Liu LL, Oei VYS, Kjällquist U, Linnarsson S, Patel S, Taskén K, Stenmark H, Malmberg KJ.

Nat Commun. 2019 Jan 31;10(1):514. doi: 10.1038/s41467-019-08384-x.

7.

FOXK1 and FOXK2 regulate aerobic glycolysis.

Sukonina V, Ma H, Zhang W, Bartesaghi S, Subhash S, Heglind M, Foyn H, Betz MJ, Nilsson D, Lidell ME, Naumann J, Haufs-Brusberg S, Palmgren H, Mondal T, Beg M, Jedrychowski MP, Taskén K, Pfeifer A, Peng XR, Kanduri C, Enerbäck S.

Nature. 2019 Feb;566(7743):279-283. doi: 10.1038/s41586-019-0900-5. Epub 2019 Jan 30.

PMID:
30700909
8.

The PI3K p110δ Isoform Inhibitor Idelalisib Preferentially Inhibits Human Regulatory T Cell Function.

Chellappa S, Kushekhar K, Munthe LA, Tjønnfjord GE, Aandahl EM, Okkenhaug K, Taskén K.

J Immunol. 2019 Mar 1;202(5):1397-1405. doi: 10.4049/jimmunol.1701703. Epub 2019 Jan 28.

PMID:
30692213
9.

EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology.

Brennecke P, Rasina D, Aubi O, Herzog K, Landskron J, Cautain B, Vicente F, Quintana J, Mestres J, Stechmann B, Ellinger B, Brea J, Kolanowski JL, Pilarski R, Orzaez M, Pineda-Lucena A, Laraia L, Nami F, Zielenkiewicz P, Paruch K, Hansen E, von Kries JP, Neuenschwander M, Specker E, Bartunek P, Simova S, Leśnikowski Z, Krauss S, Lehtiö L, Bilitewski U, Brönstrup M, Taskén K, Jirgensons A, Lickert H, Clausen MH, Andersen JH, Vicent MJ, Genilloud O, Martinez A, Nazaré M, Fecke W, Gribbon P.

SLAS Discov. 2019 Mar;24(3):398-413. doi: 10.1177/2472555218816276. Epub 2019 Jan 7.

PMID:
30616481
10.

Cryopreservation of primary B cells minimally influences their signaling responses.

Hermansen JU, Tjønnfjord GE, Munthe LA, Taskén K, Skånland SS.

Sci Rep. 2018 Dec 5;8(1):17651. doi: 10.1038/s41598-018-36121-9.

11.

Levels and prognostic impact of circulating markers of inflammation, endothelial activation and extracellular matrix remodelling in patients with lung cancer and chronic obstructive pulmonary disease.

Berg J, Halvorsen AR, Bengtson MB, Taskén KA, Mælandsmo GM, Yndestad A, Halvorsen B, Brustugun OT, Aukrust P, Ueland T, Helland Å.

BMC Cancer. 2018 Jul 13;18(1):739. doi: 10.1186/s12885-018-4659-0.

12.

Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4-insufficient subjects.

Schwab C, Gabrysch A, Olbrich P, Patiño V, Warnatz K, Wolff D, Hoshino A, Kobayashi M, Imai K, Takagi M, Dybedal I, Haddock JA, Sansom DM, Lucena JM, Seidl M, Schmitt-Graeff A, Reiser V, Emmerich F, Frede N, Bulashevska A, Salzer U, Schubert D, Hayakawa S, Okada S, Kanariou M, Kucuk ZY, Chapdelaine H, Petruzelkova L, Sumnik Z, Sediva A, Slatter M, Arkwright PD, Cant A, Lorenz HM, Giese T, Lougaris V, Plebani A, Price C, Sullivan KE, Moutschen M, Litzman J, Freiberger T, van de Veerdonk FL, Recher M, Albert MH, Hauck F, Seneviratne S, Pachlopnik Schmid J, Kolios A, Unglik G, Klemann C, Speckmann C, Ehl S, Leichtner A, Blumberg R, Franke A, Snapper S, Zeissig S, Cunningham-Rundles C, Giulino-Roth L, Elemento O, Dückers G, Niehues T, Fronkova E, Kanderová V, Platt CD, Chou J, Chatila TA, Geha R, McDermott E, Bunn S, Kurzai M, Schulz A, Alsina L, Casals F, Deyà-Martinez A, Hambleton S, Kanegane H, Taskén K, Neth O, Grimbacher B.

J Allergy Clin Immunol. 2018 Dec;142(6):1932-1946. doi: 10.1016/j.jaci.2018.02.055. Epub 2018 May 4.

PMID:
29729943
13.

OPA1-anchored PKA phosphorylates perilipin 1 on S522 and S497 in adipocytes differentiated from human adipose stem cells.

Rogne M, Chu DT, Küntziger TM, Mylonakou MN, Collas P, Tasken K.

Mol Biol Cell. 2018 Jun 15;29(12):1487-1501. doi: 10.1091/mbc.E17-09-0538. Epub 2018 Apr 24.

14.

Role of serum response factor expression in prostate cancer biochemical recurrence.

Prencipe M, Fabre A, Murphy TB, Vargyas E, O'Neill A, Bjartell A, Tasken KA, Grytli HH, Svindland A, Berge V, Eri LM, Gallagher W, Watson RW.

Prostate. 2018 Jul;78(10):724-730. doi: 10.1002/pros.23516. Epub 2018 Apr 2.

PMID:
29608018
15.

Single cell profiling of phospho-protein levels in chronic lymphocytic leukemia.

Myhrvold IK, Cremaschi A, Hermansen JU, Tjønnfjord GE, Munthe LA, Taskén K, Skånland SS.

Oncotarget. 2018 Jan 4;9(10):9273-9284. doi: 10.18632/oncotarget.23949. eCollection 2018 Feb 6.

16.

Ex vivo metabolic fingerprinting identifies biomarkers predictive of prostate cancer recurrence following radical prostatectomy.

Braadland PR, Giskeødegård G, Sandsmark E, Bertilsson H, Euceda LR, Hansen AF, Guldvik IJ, Selnæs KM, Grytli HH, Katz B, Svindland A, Bathen TF, Eri LM, Nygård S, Berge V, Taskén KA, Tessem MB.

Br J Cancer. 2018 Mar 20;118(6):e11. doi: 10.1038/bjc.2017.470. Epub 2018 Feb 20.

17.

Ezrin-anchored PKA phosphorylates serine 369 and 373 on connexin 43 to enhance gap junction assembly, communication, and cell fusion.

Dukic AR, Gerbaud P, Guibourdenche J, Thiede B, Taskén K, Pidoux G.

Biochem J. 2018 Jan 31;475(2):455-476. doi: 10.1042/BCJ20170529. Erratum in: Biochem J. 2019 Jul 2;476(13):1927.

PMID:
29259079
18.

Reply to M. Løberg et al.

Bains SJ, Mahic M, Myklebust TÅ, Småstuen MC, Yaqub S, Dørum LM, Bjørnbeth BA, Møller B, Brudvik KW, Taskén K.

J Clin Oncol. 2017 Feb 10;35(5):569-571. doi: 10.1200/JCO.2016.70.8263. Epub 2016 Nov 14. No abstract available.

PMID:
29236616
19.

Ex vivo metabolic fingerprinting identifies biomarkers predictive of prostate cancer recurrence following radical prostatectomy.

Braadland PR, Giskeødegård G, Sandsmark E, Bertilsson H, Euceda LR, Hansen AF, Guldvik IJ, Selnæs KM, Grytli HH, Katz B, Svindland A, Bathen TF, Eri LM, Nygård S, Berge V, Taskén KA, Tessem MB.

Br J Cancer. 2017 Nov 21;117(11):1656-1664. doi: 10.1038/bjc.2017.346. Epub 2017 Oct 3. Erratum in: Br J Cancer. 2018 Feb 20;:.

20.

C77G in PTPRC (CD45) is no risk allele for ovarian cancer, but associated with less aggressive disease.

Landskron J, Kraggerud SM, Wik E, Dørum A, Bjørnslett M, Melum E, Helland Ø, Bjørge L, Lothe RA, Salvesen HB, Taskén K.

PLoS One. 2017 Jul 31;12(7):e0182030. doi: 10.1371/journal.pone.0182030. eCollection 2017.

21.

Defective IL-4 signaling in T cells defines severe common variable immunodeficiency.

Taraldsrud E, Fevang B, Jørgensen SF, Moltu K, Hilden V, Taskén K, Aukrust P, Myklebust JH, Olweus J.

J Autoimmun. 2017 Jul;81:110-119. doi: 10.1016/j.jaut.2017.04.004. Epub 2017 May 3.

PMID:
28476239
22.

Immune activation and HIV-specific T cell responses are modulated by a cyclooxygenase-2 inhibitor in untreated HIV-infected individuals: An exploratory clinical trial.

Prebensen C, Trøseid M, Ueland T, Dahm A, Sandset PM, Aaberge I, Waalen K, Dyrhol-Riise AM, Taskén K, Kvale D.

PLoS One. 2017 May 2;12(5):e0176527. doi: 10.1371/journal.pone.0176527. eCollection 2017.

23.

OPA1 in Lipid Metabolism: Function of OPA1 in Lipolysis and Thermogenesis of Adipocytes.

Chu DT, Tao Y, Taskén K.

Horm Metab Res. 2017 Apr;49(4):276-285. doi: 10.1055/s-0043-100384. Epub 2017 Apr 20. Review.

PMID:
28427098
24.

Autologous bone marrow Th cells can support multiple myeloma cell proliferation in vitro and in xenografted mice.

Wang D, Fløisand Y, Myklebust CV, Bürgler S, Parente-Ribes A, Hofgaard PO, Bogen B, Taskén K, Tjønnfjord GE, Schjesvold F, Dalgaard J, Tveita A, Munthe LA.

Leukemia. 2017 Oct;31(10):2114-2121. doi: 10.1038/leu.2017.69. Epub 2017 Feb 24.

PMID:
28232741
25.

A protein kinase A-ezrin complex regulates connexin 43 gap junction communication in liver epithelial cells.

Dukic AR, Haugen LH, Pidoux G, Leithe E, Bakke O, Taskén K.

Cell Signal. 2017 Apr;32:1-11. doi: 10.1016/j.cellsig.2017.01.008. Epub 2017 Jan 8.

PMID:
28077322
26.

CD8+ T Cells That Coexpress RORγt and T-bet Are Functionally Impaired and Expand in Patients with Distal Bile Duct Cancer.

Chellappa S, Hugenschmidt H, Hagness M, Subramani S, Melum E, Line PD, Labori KJ, Wiedswang G, Taskén K, Aandahl EM.

J Immunol. 2017 Feb 15;198(4):1729-1739. doi: 10.4049/jimmunol.1600061. Epub 2017 Jan 4.

27.

Observed correlation between the expression levels of catalytic subunit, Cβ2, of cyclic adenosine monophosphate-dependent protein kinase and prostate cancer aggressiveness.

Moen LV, Ramberg H, Zhao S, Grytli HH, Sveen A, Berge V, Skotheim RI, Taskén KA, Skålhegg BS.

Urol Oncol. 2017 Mar;35(3):111.e1-111.e8. doi: 10.1016/j.urolonc.2016.10.002. Epub 2016 Nov 9.

PMID:
27838142
28.

The COX- inhibitor indomethacin reduces Th1 effector and T regulatory cells in vitro in Mycobacterium tuberculosis infection.

Tonby K, Wergeland I, Lieske NV, Kvale D, Tasken K, Dyrhol-Riise AM.

BMC Infect Dis. 2016 Oct 24;16(1):599.

29.

Proximal signaling responses in peripheral T cells from colorectal cancer patients are affected by high concentrations of circulating prostaglandin E2.

Moltu K, Henjum K, Oberprieler NG, Bjørnbeth BA, Taskén K.

Hum Immunol. 2017 Feb;78(2):129-137. doi: 10.1016/j.humimm.2016.10.007. Epub 2016 Oct 18.

PMID:
27769746
30.

Plasma IP-10 Is Increased in Immunological NonResponders and Associated With Activated Regulatory T Cells and Persisting Low CD4 Counts.

Stiksrud B, Lorvik KB, Kvale D, Mollnes TE, Ueland PM, Trøseid M, Taskén K, Dyrhol-Riise AM.

J Acquir Immune Defic Syndr. 2016 Oct 1;73(2):138-48. doi: 10.1097/QAI.0000000000001080.

PMID:
27632144
31.

A Cell-Based High-Throughput Assay for Gap Junction Communication Suitable for Assessing Connexin 43-Ezrin Interaction Disruptors Using IncuCyte ZOOM.

Dukic AR, McClymont DW, Taskén K.

SLAS Discov. 2017 Jan;22(1):77-85. doi: 10.1177/1087057116669120. Epub 2016 Sep 26.

PMID:
27628689
32.

Malonate in the nucleotide-binding site traps human AKAP18γ/δ in a novel conformational state.

Bjerregaard-Andersen K, Østensen E, Scott JD, Taskén K, Morth JP.

Acta Crystallogr F Struct Biol Commun. 2016 Aug;72(Pt 8):591-7. doi: 10.1107/S2053230X16010189. Epub 2016 Jul 13.

33.

Tomato-based randomized controlled trial in prostate cancer patients: Effect on PSA.

Paur I, Lilleby W, Bøhn SK, Hulander E, Klein W, Vlatkovic L, Axcrona K, Bolstad N, Bjøro T, Laake P, Taskén KA, Svindland A, Eri LM, Brennhovd B, Carlsen MH, Fosså SD, Smeland SS, Karlsen AS, Blomhoff R.

Clin Nutr. 2017 Jun;36(3):672-679. doi: 10.1016/j.clnu.2016.06.014. Epub 2016 Jun 30.

34.

Molecular Mechanisms for cAMP-Mediated Immunoregulation in T cells - Role of Anchored Protein Kinase A Signaling Units.

Wehbi VL, Taskén K.

Front Immunol. 2016 Jun 8;7:222. doi: 10.3389/fimmu.2016.00222. eCollection 2016. Review.

35.

PBX3 is a putative biomarker of aggressive prostate cancer.

Ramberg H, Grytli HH, Nygård S, Wang W, Ögren O, Zhao S, Løvf M, Katz B, Skotheim RI, Bjartell A, Eri LM, Berge V, Svindland A, Taskén KA.

Int J Cancer. 2016 Oct 15;139(8):1810-20. doi: 10.1002/ijc.30220. Epub 2016 Jun 25.

36.

Aspirin As Secondary Prevention in Patients With Colorectal Cancer: An Unselected Population-Based Study.

Bains SJ, Mahic M, Myklebust TÅ, Småstuen MC, Yaqub S, Dørum LM, Bjørnbeth BA, Møller B, Brudvik KW, Taskén K.

J Clin Oncol. 2016 Jul 20;34(21):2501-8. doi: 10.1200/JCO.2015.65.3519. Epub 2016 May 31.

PMID:
27247217
37.

Regulatory T cells that co-express RORγt and FOXP3 are pro-inflammatory and immunosuppressive and expand in human pancreatic cancer.

Chellappa S, Hugenschmidt H, Hagness M, Line PD, Labori KJ, Wiedswang G, Taskén K, Aandahl EM.

Oncoimmunology. 2015 Oct 29;5(4):e1102828. eCollection 2016 Apr.

38.

Critical Role of CD2 Co-stimulation in Adaptive Natural Killer Cell Responses Revealed in NKG2C-Deficient Humans.

Liu LL, Landskron J, Ask EH, Enqvist M, Sohlberg E, Traherne JA, Hammer Q, Goodridge JP, Larsson S, Jayaraman J, Oei VYS, Schaffer M, Taskén K, Ljunggren HG, Romagnani C, Trowsdale J, Malmberg KJ, Béziat V.

Cell Rep. 2016 May 3;15(5):1088-1099. doi: 10.1016/j.celrep.2016.04.005. Epub 2016 Apr 21.

39.

Human regulatory T cells control TCR signaling and susceptibility to suppression in CD4+ T cells.

Chellappa S, Lieske NV, Hagness M, Line PD, Taskén K, Aandahl EM.

J Leukoc Biol. 2016 Jul;100(1):5-16. doi: 10.1189/jlb.2HI0815-334R. Epub 2015 Dec 29.

PMID:
26715685
40.

Low β₂-adrenergic receptor level may promote development of castration resistant prostate cancer and altered steroid metabolism.

Braadland PR, Grytli HH, Ramberg H, Katz B, Kellman R, Gauthier-Landry L, Fazli L, Krobert KA, Wang W, Levy FO, Bjartell A, Berge V, Rennie PS, Mellgren G, Mælandsmo GM, Svindland A, Barbier O, Taskén KA.

Oncotarget. 2016 Jan 12;7(2):1878-94. doi: 10.18632/oncotarget.6479.

41.

Spleen tyrosine kinase inhibitors reduce CD40L-induced proliferation of chronic lymphocytic leukemia cells but not normal B cells.

Parente-Ribes A, Skånland SS, Bürgler S, Os A, Wang D, Bogen B, Tjønnfjord GE, Taskén K, Munthe LA.

Haematologica. 2016 Feb;101(2):e59-62. doi: 10.3324/haematol.2015.135590. Epub 2015 Nov 20. No abstract available.

42.

Phosphoprotein Detection by High-Throughput Flow Cytometry.

Landskron J, Taskén K.

Methods Mol Biol. 2016;1355:275-90. doi: 10.1007/978-1-4939-3049-4_19.

PMID:
26584933
43.

Targeting Tuberculosis and HIV Infection-Specific Regulatory T Cells with MEK/ERK Signaling Pathway Inhibitors.

Lieske NV, Tonby K, Kvale D, Dyrhol-Riise AM, Tasken K.

PLoS One. 2015 Nov 6;10(11):e0141903. doi: 10.1371/journal.pone.0141903. eCollection 2015.

44.

Anchored PKA as a gatekeeper for gap junctions.

Pidoux G, Taskén K.

Commun Integr Biol. 2015 Aug 31;8(4):e1057361. doi: 10.1080/19420889.2015.1057361. eCollection 2015 Jul-Aug.

45.

Spatiotemporal regulation of cAMP signaling controls the human trophoblast fusion.

Gerbaud P, Taskén K, Pidoux G.

Front Pharmacol. 2015 Sep 15;6:202. doi: 10.3389/fphar.2015.00202. eCollection 2015.

46.

Targeting protein-protein interactions in complexes organized by A kinase anchoring proteins.

Calejo AI, Taskén K.

Front Pharmacol. 2015 Sep 8;6:192. doi: 10.3389/fphar.2015.00192. eCollection 2015. Review.

47.

Targeting of type I protein kinase A to lipid rafts is required for platelet inhibition by the 3',5'-cyclic adenosine monophosphate-signaling pathway.

Raslan Z, Magwenzi S, Aburima A, Taskén K, Naseem KM.

J Thromb Haemost. 2015 Sep;13(9):1721-34. doi: 10.1111/jth.13042. Epub 2015 Aug 12.

48.

Monitoring regulatory T cells in clinical samples: consensus on an essential marker set and gating strategy for regulatory T cell analysis by flow cytometry.

Santegoets SJ, Dijkgraaf EM, Battaglia A, Beckhove P, Britten CM, Gallimore A, Godkin A, Gouttefangeas C, de Gruijl TD, Koenen HJ, Scheffold A, Shevach EM, Staats J, Taskén K, Whiteside TL, Kroep JR, Welters MJ, van der Burg SH.

Cancer Immunol Immunother. 2015 Oct;64(10):1271-86. doi: 10.1007/s00262-015-1729-x. Epub 2015 Jun 28.

49.

β-Adrenergic Receptor Signaling in Prostate Cancer.

Braadland PR, Ramberg H, Grytli HH, Taskén KA.

Front Oncol. 2015 Jan 12;4:375. doi: 10.3389/fonc.2014.00375. eCollection 2014. Review.

50.

Activated regulatory and memory T-cells accumulate in malignant ascites from ovarian carcinoma patients.

Landskron J, Helland Ø, Torgersen KM, Aandahl EM, Gjertsen BT, Bjørge L, Taskén K.

Cancer Immunol Immunother. 2015 Mar;64(3):337-47. doi: 10.1007/s00262-014-1636-6. Epub 2014 Nov 22.

PMID:
25416072

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