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Items: 40


Diagnostic Interpretation of Genetic Studies in Patients with Primary Immunodeficiency Diseases: A Working Group Report of the Primary Immunodeficiency Diseases Committee of the American Academy of Allergy, Asthma, and Immunology.

Chinn IK, Chan A, Chen K, Chou J, Dorsey MJ, Hajjar J, Jongco AM 3rd, Keller MD, Kobrynski LJ, Kumanovics A, Lawrence MG, Leiding JW, Lugar PL, Orange JS, Patel K, Platt CD, Puck JM, Raje N, Romberg ND, Slack MA, Sullivan KE, Tarrant TK, Torgerson TR, Walter JE.

J Allergy Clin Immunol. 2019 Sep 27. pii: S0091-6749(19)31245-X. doi: 10.1016/j.jaci.2019.09.009. [Epub ahead of print]


On Command Drug Delivery via Cell-Conveyed Phototherapeutics.

Marvin CM, Ding S, White RE, Orlova N, Wang Q, Zywot EM, Vickerman BM, Harr L, Tarrant TK, Dayton PA, Lawrence DS.

Small. 2019 Sep;15(37):e1901442. doi: 10.1002/smll.201901442. Epub 2019 Jul 28.


Laser Light Therapy in Inflammatory, Musculoskeletal, and Autoimmune Disease.

Wickenheisser VA, Zywot EM, Rabjohns EM, Lee HH, Lawrence DS, Tarrant TK.

Curr Allergy Asthma Rep. 2019 Jul 2;19(8):37. doi: 10.1007/s11882-019-0869-z.


Chemerin-activated functions of CMKLR1 are regulated by G protein-coupled receptor kinase 6 (GRK6) and β-arrestin 2 in inflammatory macrophages.

Serafin DS, Allyn B, Sassano MF, Timoshchenko RG, Mattox D, Brozowski JM, Siderovski DP, Truong YK, Esserman D, Tarrant TK, Billard MJ.

Mol Immunol. 2019 Feb;106:12-21. doi: 10.1016/j.molimm.2018.12.016. Epub 2018 Dec 18.


Chronic norovirus infection in primary immune deficiency disorders: an international case series.

Rolfes MC, Sriaroon P, Dávila Saldaña BJ, Dvorak CC, Chapdelaine H, Ferdman RM, Chen K, Jolles S, Patel NC, Kim YJ, Tarrant TK, Martelius T, Seppanen M, Joshi AY.

Diagn Microbiol Infect Dis. 2019 Jan;93(1):69-73. doi: 10.1016/j.diagmicrobio.2018.08.002. Epub 2018 Aug 12.


A functional genomics predictive network model identifies regulators of inflammatory bowel disease.

Peters LA, Perrigoue J, Mortha A, Iuga A, Song WM, Neiman EM, Llewellyn SR, Di Narzo A, Kidd BA, Telesco SE, Zhao Y, Stojmirovic A, Sendecki J, Shameer K, Miotto R, Losic B, Shah H, Lee E, Wang M, Faith JJ, Kasarskis A, Brodmerkel C, Curran M, Das A, Friedman JR, Fukui Y, Humphrey MB, Iritani BM, Sibinga N, Tarrant TK, Argmann C, Hao K, Roussos P, Zhu J, Zhang B, Dobrin R, Mayer LF, Schadt EE.

Nat Genet. 2017 Oct;49(10):1437-1449. doi: 10.1038/ng.3947. Epub 2017 Sep 11.


Immune Gamma Globulin Therapeutic Indications in Immune Deficiency and Autoimmunity.

Yang L, Wu EY, Tarrant TK.

Curr Allergy Asthma Rep. 2016 Jul;16(8):55. doi: 10.1007/s11882-016-0632-7. Review.


Single Cell Chemical Cytometry of Akt Activity in Rheumatoid Arthritis and Normal Fibroblast-like Synoviocytes in Response to Tumor Necrosis Factor α.

Mainz ER, Serafin DS, Nguyen TT, Tarrant TK, Sims CE, Allbritton NL.

Anal Chem. 2016 Aug 2;88(15):7786-92. doi: 10.1021/acs.analchem.6b01801. Epub 2016 Jul 20.


Apoptotic Debris Accumulates on Hematopoietic Cells and Promotes Disease in Murine and Human Systemic Lupus Erythematosus.

Kang S, Rogers JL, Monteith AJ, Jiang C, Schmitz J, Clarke SH, Tarrant TK, Truong YK, Diaz M, Fedoriw Y, Vilen BJ.

J Immunol. 2016 May 15;196(10):4030-9. doi: 10.4049/jimmunol.1500418. Epub 2016 Apr 8.


G Protein Coupled Receptor Kinase 3 Regulates Breast Cancer Migration, Invasion, and Metastasis.

Billard MJ, Fitzhugh DJ, Parker JS, Brozowski JM, McGinnis MW, Timoshchenko RG, Serafin DS, Lininger R, Klauber-Demore N, Sahagian G, Truong YK, Sassano MF, Serody JS, Tarrant TK.

PLoS One. 2016 Apr 6;11(4):e0152856. doi: 10.1371/journal.pone.0152856. eCollection 2016.


Clinically focused exome sequencing identifies an homozygous mutation that confers DOCK8 deficiency.

Burbank AJ, Shah SN, Montgomery M, Peden D, Tarrant TK, Weimer ET.

Pediatr Allergy Immunol. 2016 Feb;27(1):96-8. doi: 10.1111/pai.12451. Epub 2015 Oct 12. No abstract available.


Roles of chemokines CCL2 and CCL5 in the pharmacokinetics of PEGylated liposomal doxorubicin in vivo and in patients with recurrent epithelial ovarian cancer.

Song G, Tarrant TK, White TF, Barrow DA, Santos CM, Timoshchenko RG, Hanna SK, Ramanathan RK, Lee CR, Bae-Jump VL, Gehrig PA, Zamboni WC.

Nanomedicine. 2015 Oct;11(7):1797-807. doi: 10.1016/j.nano.2015.05.007. Epub 2015 Jun 17.


Nanoscience advances in rheumatology and immunology.

Tarrant TK.

Curr Rheumatol Rev. 2014;10(1):1-2. No abstract available.


Effects of tumor microenvironment heterogeneity on nanoparticle disposition and efficacy in breast cancer tumor models.

Song G, Darr DB, Santos CM, Ross M, Valdivia A, Jordan JL, Midkiff BR, Cohen S, Nikolaishvili-Feinberg N, Miller CR, Tarrant TK, Rogers AB, Dudley AC, Perou CM, Zamboni WC.

Clin Cancer Res. 2014 Dec 1;20(23):6083-95. doi: 10.1158/1078-0432.CCR-14-0493. Epub 2014 Sep 17.


G protein signaling modulator-3: a leukocyte regulator of inflammation in health and disease.

Billard MJ, Gall BJ, Richards KL, Siderovski DP, Tarrant TK.

Am J Clin Exp Immunol. 2014 Aug 15;3(2):97-106. eCollection 2014. Review.


Autoimmune lymphoproliferative syndrome: an update and review of the literature.

Shah S, Wu E, Rao VK, Tarrant TK.

Curr Allergy Asthma Rep. 2014 Sep;14(9):462. doi: 10.1007/s11882-014-0462-4. Review.


Targeting the molecular and cellular interactions of the bone marrow niche in immunologic disease.

Brozowski JM, Billard MJ, Tarrant TK.

Curr Allergy Asthma Rep. 2014 Feb;14(2):402. doi: 10.1007/s11882-013-0402-8. Review.


G protein-coupled receptor kinase-3-deficient mice exhibit WHIM syndrome features and attenuated inflammatory responses.

Tarrant TK, Billard MJ, Timoshchenko RG, McGinnis MW, Serafin DS, Foreman O, Esserman DA, Chao NJ, Lento WE, Lee DM, Patel D, Siderovski DP.

J Leukoc Biol. 2013 Dec;94(6):1243-51. doi: 10.1189/jlb.0213097. Epub 2013 Aug 9.


Autoimmunity in immunodeficiency.

Todoric K, Koontz JB, Mattox D, Tarrant TK.

Curr Allergy Asthma Rep. 2013 Aug;13(4):361-70. doi: 10.1007/s11882-013-0350-3. Review.


G-protein signaling modulator-3, a gene linked to autoimmune diseases, regulates monocyte function and its deficiency protects from inflammatory arthritis.

Giguère PM, Billard MJ, Laroche G, Buckley BK, Timoshchenko RG, McGinnis MW, Esserman D, Foreman O, Liu P, Siderovski DP, Tarrant TK.

Mol Immunol. 2013 Jun;54(2):193-8. doi: 10.1016/j.molimm.2012.12.001. Epub 2012 Dec 29.


Cellular targeting in autoimmunity.

Rogers JL, Serafin DS, Timoshchenko RG, Tarrant TK.

Curr Allergy Asthma Rep. 2012 Dec;12(6):495-510. doi: 10.1007/s11882-012-0307-y. Review.


Decreased Th17 and antigen-specific humoral responses in CX₃ CR1-deficient mice in the collagen-induced arthritis model.

Tarrant TK, Liu P, Rampersad RR, Esserman D, Rothlein LR, Timoshchenko RG, McGinnis MW, Fitzhugh DJ, Patel DD, Fong AM.

Arthritis Rheum. 2012 May;64(5):1379-87. doi: 10.1002/art.34320.


Second generation automated anti-CCP test better predicts the clinical diagnosis of rheumatoid arthritis.

Elrefaei M, Boose K, McGee M, Tarrant TK, Lin FC, Fine JP, Schmitz JL.

J Clin Immunol. 2012 Feb;32(1):131-7. doi: 10.1007/s10875-011-9610-y. Epub 2011 Nov 10.


Enhanced Th17-cell responses render CCR2-deficient mice more susceptible for autoimmune arthritis.

Rampersad RR, Tarrant TK, Vallanat CT, Quintero-Matthews T, Weeks MF, Esserman DA, Clark J, Di Padova F, Patel DD, Fong AM, Liu P.

PLoS One. 2011;6(10):e25833. doi: 10.1371/journal.pone.0025833. Epub 2011 Oct 4.


Sclerosing mesenteritis successfully treated with a TNF antagonist.

Rothlein LR, Shaheen AW, Vavalle JP, Smith SV, Renner JB, Shaheen NJ, Tarrant TK.

BMJ Case Rep. 2010 Dec 20;2010. pii: bcr0720103145. doi: 10.1136/bcr.07.2010.3145.


S100A9 is not essential for disease expression in an acute (K/BxN) or chronic (CIA) model of inflammatory arthritis.

Rampersad RR, Esserman D, McGinnis MW, Lee DM, Patel DD, Tarrant TK.

Scand J Rheumatol. 2009 Nov-Dec;38(6):445-9. doi: 10.3109/03009740902895743.


Multimodal optical and Gd-based nanoparticles for imaging in inflammatory arthritis.

Kim JS, An H, Rieter WJ, Esserman D, Taylor-Pashow KM, Sartor RB, Lin W, Lin W, Tarrant TK.

Clin Exp Rheumatol. 2009 Jul-Aug;27(4):580-6.


A desensitization protocol for the mAb cetuximab.

Jerath MR, Kwan M, Kannarkat M, Mirakhur B, Carey L, Valgus J, Platts-Mills TA, Tarrant TK.

J Allergy Clin Immunol. 2009 Jan;123(1):260-2. doi: 10.1016/j.jaci.2008.09.046. Epub 2008 Nov 20. No abstract available.


Granulocyte chemotaxis and disease expression are differentially regulated by GRK subtype in an acute inflammatory arthritis model (K/BxN).

Tarrant TK, Rampersad RR, Esserman D, Rothlein LR, Liu P, Premont RT, Lefkowitz RJ, Lee DM, Patel DD.

Clin Immunol. 2008 Oct;129(1):115-22. doi: 10.1016/j.clim.2008.06.008. Epub 2008 Jul 26.


An Endogenous TNF-α Antagonist Induced by Splice-switching Oligonucleotides Reduces Inflammation in Hepatitis and Arthritis Mouse Models.

Graziewicz MA, Tarrant TK, Buckley B, Roberts J, Fulton L, Hansen H, Ørum H, Kole R, Sazani P.

Mol Ther. 2008 Jul;16(7):1316-1322. doi: 10.1038/mt.2008.85. Epub 2016 Dec 8.


An endogenous TNF-alpha antagonist induced by splice-switching oligonucleotides reduces inflammation in hepatitis and arthritis mouse models.

Graziewicz MA, Tarrant TK, Buckley B, Roberts J, Fulton L, Hansen H, Ørum H, Kole R, Sazani P.

Mol Ther. 2008 Jul;16(7):1316-22. doi: 10.1038/mt.2008.85. Epub 2008 May 6.


Chemokines and leukocyte trafficking in rheumatoid arthritis.

Tarrant TK, Patel DD.

Pathophysiology. 2006 Feb 21;13(1):1-14. Epub 2005 Dec 27.


Tgf-beta inhibits activation and uveitogenicity of primary but not of fully polarized retinal antigen-specific memory-effector T cells.

Xu H, Silver PB, Tarrant TK, Chan CC, Caspi RR.

Invest Ophthalmol Vis Sci. 2003 Nov;44(11):4805-12.


B cell loss leading to remission in severe systemic lupus erythematosus.

Tarrant TK, Frazer DH, Aya-Ay JP, Patel DD.

J Rheumatol. 2003 Feb;30(2):412-4. Review.


Mice deficient in inducible nitric oxide synthase are susceptible to experimental autoimmune uveoretinitis.

Silver PB, Tarrant TK, Chan CC, Wiggert B, Caspi RR.

Invest Ophthalmol Vis Sci. 1999 May;40(6):1280-4.


Endogenous IL-12 is required for induction and expression of experimental autoimmune uveitis.

Tarrant TK, Silver PB, Chan CC, Wiggert B, Caspi RR.

J Immunol. 1998 Jul 1;161(1):122-7.


T cell traffic and the inflammatory response in experimental autoimmune uveoretinitis.

Prendergast RA, Iliff CE, Coskuncan NM, Caspi RR, Sartani G, Tarrant TK, Lutty GA, McLeod DS.

Invest Ophthalmol Vis Sci. 1998 Apr;39(5):754-62.


IFN-gamma-deficient mice develop experimental autoimmune uveitis in the context of a deviant effector response.

Jones LS, Rizzo LV, Agarwal RK, Tarrant TK, Chan CC, Wiggert B, Caspi RR.

J Immunol. 1997 Jun 15;158(12):5997-6005.


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