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Items: 41

1.

Activation of β-Catenin Cooperates with Loss of Pten to Drive AR-Independent Castration-Resistant Prostate Cancer.

Patel R, Brzezinska EA, Repiscak P, Ahmad I, Mui E, Gao M, Blomme A, Harle V, Tan EH, Malviya G, Mrowinska A, Loveridge CJ, Rushworth LK, Edwards J, Ntala C, Nixon C, Hedley A, Mackay G, Tardito S, Sansom OJ, Leung HY.

Cancer Res. 2020 Feb 1;80(3):576-590. doi: 10.1158/0008-5472.CAN-19-1684. Epub 2019 Nov 12.

2.

Macrophage M1/M2 polarization and rheumatoid arthritis: A systematic review.

Tardito S, Martinelli G, Soldano S, Paolino S, Pacini G, Patane M, Alessandri E, Smith V, Cutolo M.

Autoimmun Rev. 2019 Nov;18(11):102397. doi: 10.1016/j.autrev.2019.102397. Epub 2019 Sep 11.

PMID:
31520798
3.

Cell Culture Medium Formulation and Its Implications in Cancer Metabolism.

Ackermann T, Tardito S.

Trends Cancer. 2019 Jun;5(6):329-332. doi: 10.1016/j.trecan.2019.05.004. Epub 2019 May 29.

4.

Innovations in the Assessment of Primary and Secondary Raynaud's Phenomenon.

Ruaro B, Smith V, Sulli A, Pizzorni C, Tardito S, Patané M, Paolino S, Cutolo M.

Front Pharmacol. 2019 Apr 16;10:360. doi: 10.3389/fphar.2019.00360. eCollection 2019.

5.

Correlation between circulating fibrocytes and dermal thickness in limited cutaneous systemic sclerosis patients: a pilot study.

Ruaro B, Soldano S, Smith V, Paolino S, Contini P, Montagna P, Pizzorni C, Casabella A, Tardito S, Sulli A, Cutolo M.

Rheumatol Int. 2019 Aug;39(8):1369-1376. doi: 10.1007/s00296-019-04315-7. Epub 2019 May 6.

PMID:
31056725
6.

Improving the metabolic fidelity of cancer models with a physiological cell culture medium.

Vande Voorde J, Ackermann T, Pfetzer N, Sumpton D, Mackay G, Kalna G, Nixon C, Blyth K, Gottlieb E, Tardito S.

Sci Adv. 2019 Jan 2;5(1):eaau7314. doi: 10.1126/sciadv.aau7314. eCollection 2019 Jan.

7.

White matter microstructure alterations correlate with terminally differentiated CD8+ effector T cell depletion in the peripheral blood in mania: Combined DTI and immunological investigation in the different phases of bipolar disorder.

Magioncalda P, Martino M, Tardito S, Sterlini B, Conio B, Marozzi V, Adavastro G, Capobianco L, Russo D, Parodi A, Kalli F, Nasi G, Altosole T, Piaggio N, Northoff G, Fenoglio D, Inglese M, Filaci G, Amore M.

Brain Behav Immun. 2018 Oct;73:192-204. doi: 10.1016/j.bbi.2018.04.017. Epub 2018 May 1.

PMID:
29723656
8.

Oligodendroglioma Cells Lack Glutamine Synthetase and Are Auxotrophic for Glutamine, but Do not Depend on Glutamine Anaplerosis for Growth.

Chiu M, Taurino G, Bianchi MG, Ottaviani L, Andreoli R, Ciociola T, Lagrasta CAM, Tardito S, Bussolati O.

Int J Mol Sci. 2018 Apr 6;19(4). pii: E1099. doi: 10.3390/ijms19041099.

9.

Altered metabolic landscape in IDH-mutant gliomas affects phospholipid, energy, and oxidative stress pathways.

Fack F, Tardito S, Hochart G, Oudin A, Zheng L, Fritah S, Golebiewska A, Nazarov PV, Bernard A, Hau AC, Keunen O, Leenders W, Lund-Johansen M, Stauber J, Gottlieb E, Bjerkvig R, Niclou SP.

EMBO Mol Med. 2017 Dec;9(12):1681-1695. doi: 10.15252/emmm.201707729.

10.

Targeting mitochondrial oxidative phosphorylation eradicates therapy-resistant chronic myeloid leukemia stem cells.

Kuntz EM, Baquero P, Michie AM, Dunn K, Tardito S, Holyoake TL, Helgason GV, Gottlieb E.

Nat Med. 2017 Oct;23(10):1234-1240. doi: 10.1038/nm.4399. Epub 2017 Sep 18.

11.

Phenotypic Alterations Involved in CD8+ Treg Impairment in Systemic Sclerosis.

Negrini S, Fenoglio D, Parodi A, Kalli F, Battaglia F, Nasi G, Curto M, Tardito S, Ferrera F, Filaci G.

Front Immunol. 2017 Jan 19;8:18. doi: 10.3389/fimmu.2017.00018. eCollection 2017.

12.

Cancer metabolism at a glance.

Vazquez A, Kamphorst JJ, Markert EK, Schug ZT, Tardito S, Gottlieb E.

J Cell Sci. 2016 Sep 15;129(18):3367-73. doi: 10.1242/jcs.181016. Review.

13.

AIRE polymorphism, melanoma antigen-specific T cell immunity, and susceptibility to melanoma.

Conteduca G, Fenoglio D, Parodi A, Battaglia F, Kalli F, Negrini S, Tardito S, Ferrera F, Salis A, Millo E, Pasquale G, Barra G, Damonte G, Indiveri F, Ferrone S, Filaci G.

Oncotarget. 2016 Sep 20;7(38):60872-60884. doi: 10.18632/oncotarget.11506.

14.

Residual tumor micro-foci and overwhelming regulatory T lymphocyte infiltration are the causes of bladder cancer recurrence.

Parodi A, Traverso P, Kalli F, Conteduca G, Tardito S, Curto M, Grillo F, Mastracci L, Bernardi C, Nasi G, Minaglia F, Simonato A, Carmignani G, Ferrera F, Fenoglio D, Filaci G.

Oncotarget. 2016 Feb 9;7(6):6424-35. doi: 10.18632/oncotarget.7024.

15.

Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma.

Tardito S, Oudin A, Ahmed SU, Fack F, Keunen O, Zheng L, Miletic H, Sakariassen PØ, Weinstock A, Wagner A, Lindsay SL, Hock AK, Barnett SC, Ruppin E, Mørkve SH, Lund-Johansen M, Chalmers AJ, Bjerkvig R, Niclou SP, Gottlieb E.

Nat Cell Biol. 2015 Dec;17(12):1556-68. doi: 10.1038/ncb3272. Epub 2015 Nov 23.

16.

Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress.

Schug ZT, Peck B, Jones DT, Zhang Q, Grosskurth S, Alam IS, Goodwin LM, Smethurst E, Mason S, Blyth K, McGarry L, James D, Shanks E, Kalna G, Saunders RE, Jiang M, Howell M, Lassailly F, Thin MZ, Spencer-Dene B, Stamp G, van den Broek NJ, Mackay G, Bulusu V, Kamphorst JJ, Tardito S, Strachan D, Harris AL, Aboagye EO, Critchlow SE, Wakelam MJ, Schulze A, Gottlieb E.

Cancer Cell. 2015 Jan 12;27(1):57-71. doi: 10.1016/j.ccell.2014.12.002.

17.

Glutamine depletion by crisantaspase hinders the growth of human hepatocellular carcinoma xenografts.

Chiu M, Tardito S, Pillozzi S, Arcangeli A, Armento A, Uggeri J, Missale G, Bianchi MG, Barilli A, Dall'Asta V, Campanini N, Silini EM, Fuchs J, Armeanu-Ebinger S, Bussolati O.

Br J Cancer. 2014 Sep 9;111(6):1159-67. doi: 10.1038/bjc.2014.425. Epub 2014 Jul 29.

18.

Glucose and glutamine metabolism regulate human hematopoietic stem cell lineage specification.

Oburoglu L, Tardito S, Fritz V, de Barros SC, Merida P, Craveiro M, Mamede J, Cretenet G, Mongellaz C, An X, Klysz D, Touhami J, Boyer-Clavel M, Battini JL, Dardalhon V, Zimmermann VS, Mohandas N, Gottlieb E, Sitbon M, Kinet S, Taylor N.

Cell Stem Cell. 2014 Aug 7;15(2):169-84. doi: 10.1016/j.stem.2014.06.002. Epub 2014 Jun 19. Erratum in: Cell Stem Cell. 2014 Nov 6;15(5):666-8.

19.

Polyphenon E(R), a standardized green tea extract, induces endoplasmic reticulum stress, leading to death of immortalized PNT1a cells by anoikis and tumorigenic PC3 by necroptosis.

Rizzi F, Naponelli V, Silva A, Modernelli A, Ramazzina I, Bonacini M, Tardito S, Gatti R, Uggeri J, Bettuzzi S.

Carcinogenesis. 2014 Apr;35(4):828-39. doi: 10.1093/carcin/bgt481. Epub 2013 Dec 16.

PMID:
24343359
20.

Comparative analysis of cancer vaccine settings for the selection of an effective protocol in mice.

Kalli F, Machiorlatti R, Battaglia F, Parodi A, Conteduca G, Ferrera F, Proietti M, Tardito S, Sanguineti M, Millo E, Fenoglio D, De Palma R, Inghirami G, Filaci G.

J Transl Med. 2013 May 12;11:120. doi: 10.1186/1479-5876-11-120.

21.

CD39 is highly involved in mediating the suppression activity of tumor-infiltrating CD8+ T regulatory lymphocytes.

Parodi A, Battaglia F, Kalli F, Ferrera F, Conteduca G, Tardito S, Stringara S, Ivaldi F, Negrini S, Borgonovo G, Simonato A, Traverso P, Carmignani G, Fenoglio D, Filaci G.

Cancer Immunol Immunother. 2013 May;62(5):851-62. doi: 10.1007/s00262-013-1392-z. Epub 2013 Jan 29.

22.

Indoleamine 2,3 dioxygenase gene polymorphisms correlate with CD8+ Treg impairment in systemic sclerosis.

Tardito S, Negrini S, Conteduca G, Ferrera F, Parodi A, Battaglia F, Kalli F, Fenoglio D, Cutolo M, Filaci G.

Hum Immunol. 2013 Feb;74(2):166-9. doi: 10.1016/j.humimm.2012.11.008. Epub 2012 Nov 29.

23.

Single nucleotide polymorphisms in the promoter regions of Foxp3 and ICOSLG genes are associated with Alopecia areata.

Conteduca G, Rossi A, Megiorni F, Parodi A, Ferrera F, Tardito S, Battaglia F, Kalli F, Negrini S, Pizzuti A, Rizza E, Indiveri F, Fenoglio D, Filaci G.

Clin Exp Med. 2014 Feb;14(1):91-7. doi: 10.1007/s10238-012-0224-3. Epub 2012 Nov 30.

24.

Copper-dependent cytotoxicity of 8-hydroxyquinoline derivatives correlates with their hydrophobicity and does not require caspase activation.

Tardito S, Barilli A, Bassanetti I, Tegoni M, Bussolati O, Franchi-Gazzola R, Mucchino C, Marchiò L.

J Med Chem. 2012 Dec 13;55(23):10448-59. doi: 10.1021/jm301053a. Epub 2012 Dec 3.

PMID:
23170953
25.

HIF-independent role of prolyl hydroxylases in the cellular response to amino acids.

Durán RV, MacKenzie ED, Boulahbel H, Frezza C, Heiserich L, Tardito S, Bussolati O, Rocha S, Hall MN, Gottlieb E.

Oncogene. 2013 Sep 19;32(38):4549-56. doi: 10.1038/onc.2012.465. Epub 2012 Oct 22.

26.

Glutamine stimulates mTORC1 independent of the cell content of essential amino acids.

Chiu M, Tardito S, Barilli A, Bianchi MG, Dall'Asta V, Bussolati O.

Amino Acids. 2012 Dec;43(6):2561-7. doi: 10.1007/s00726-012-1312-0. Epub 2012 May 8.

PMID:
22566039
27.

Cyclophosphamide inhibits the generation and function of CD8(+) regulatory T cells.

Traverso I, Fenoglio D, Negrini S, Parodi A, Battaglia F, Kalli F, Conteduca G, Tardito S, Traverso P, Indiveri F, Filaci G.

Hum Immunol. 2012 Mar;73(3):207-13. doi: 10.1016/j.humimm.2011.12.020. Epub 2012 Jan 14.

28.

Expanding targets for a metabolic therapy of cancer: L-asparaginase.

Covini D, Tardito S, Bussolati O, Chiarelli LR, Pasquetto MV, Digilio R, Valentini G, Scotti C.

Recent Pat Anticancer Drug Discov. 2012 Jan;7(1):4-13. Review.

PMID:
21854356
29.

L-Asparaginase and inhibitors of glutamine synthetase disclose glutamine addiction of β-catenin-mutated human hepatocellular carcinoma cells.

Tardito S, Chiu M, Uggeri J, Zerbini A, Da Ros F, Dall'Asta V, Missale G, Bussolati O.

Curr Cancer Drug Targets. 2011 Oct;11(8):929-43.

PMID:
21834755
30.

The non-proteinogenic amino acids L-methionine sulfoximine and DL-phosphinothricin activate mTOR.

Tardito S, Chiu M, Franchi-Gazzola R, Dall'Asta V, Comi P, Bussolati O.

Amino Acids. 2012 Jun;42(6):2507-12. doi: 10.1007/s00726-011-0981-4. Epub 2011 Jul 17.

PMID:
21769496
31.

Copper binding agents acting as copper ionophores lead to caspase inhibition and paraptotic cell death in human cancer cells.

Tardito S, Bassanetti I, Bignardi C, Elviri L, Tegoni M, Mucchino C, Bussolati O, Franchi-Gazzola R, Marchiò L.

J Am Chem Soc. 2011 Apr 27;133(16):6235-42. doi: 10.1021/ja109413c. Epub 2011 Mar 31.

PMID:
21452832
32.

Platelet gel in the treatment of cutaneous ulcers: the experience of the Immunohaematology and Transfusion Centre of Parma.

Bernuzzi G, Tardito S, Bussolati O, Adorni D, Cantarelli S, Fagnoni F, Rossetti A, Azzarone M, Ficarelli E, Caleffi E, Gazzola G, Franchini M.

Blood Transfus. 2010 Oct;8(4):237-47. doi: 10.2450/2009.0118-09.

33.

The thioxotriazole copper(II) complex A0 induces endoplasmic reticulum stress and paraptotic death in human cancer cells.

Tardito S, Isella C, Medico E, Marchiò L, Bevilacqua E, Hatzoglou M, Bussolati O, Franchi-Gazzola R.

J Biol Chem. 2009 Sep 4;284(36):24306-19. doi: 10.1074/jbc.M109.026583. Epub 2009 Jun 26.

34.

TOE1 interacts with p53 to modulate its transactivation potential.

Sperandio S, Tardito S, Surzycki A, Latterich M, de Belle I.

FEBS Lett. 2009 Jul 7;583(13):2165-70. doi: 10.1016/j.febslet.2009.06.004. Epub 2009 Jun 7.

35.

Synthesis, structural characterisation and solution chemistry of ruthenium(III) triazole-thiadiazine complexes.

Delferro M, Marchiò L, Tegoni M, Tardito S, Franchi-Gazzola R, Lanfranchi M.

Dalton Trans. 2009 May 21;(19):3766-73. doi: 10.1039/b823271g. Epub 2009 Mar 20.

PMID:
19417942
36.

Copper compounds in anticancer strategies.

Tardito S, Marchiò L.

Curr Med Chem. 2009;16(11):1325-48.

PMID:
19355889
37.

Glutamatergic dysfunction in schizophrenia: from basic neuroscience to clinical psychopharmacology.

Paz RD, Tardito S, Atzori M, Tseng KY.

Eur Neuropsychopharmacol. 2008 Nov;18(11):773-86. doi: 10.1016/j.euroneuro.2008.06.005. Epub 2008 Jul 23. Review.

38.

Thioamido coordination in a thioxo-1,2,4-triazole copper(II) complex enhances nonapoptotic programmed cell death associated with copper accumulation and oxidative stress in human cancer cells.

Tardito S, Bussolati O, Maffini M, Tegoni M, Giannetto M, Dall'asta V, Franchi-Gazzola R, Lanfranchi M, Pellinghelli MA, Mucchino C, Mori G, Marchio L.

J Med Chem. 2007 Apr 19;50(8):1916-24. Epub 2007 Mar 21.

PMID:
17373781
39.

The inhibition of glutamine synthetase sensitizes human sarcoma cells to L-asparaginase.

Tardito S, Uggeri J, Bozzetti C, Bianchi MG, Rotoli BM, Franchi-Gazzola R, Gazzola GC, Gatti R, Bussolati O.

Cancer Chemother Pharmacol. 2007 Oct;60(5):751-8. Epub 2007 Jan 26.

PMID:
17256128
40.

Non-apoptotic programmed cell death induced by a copper(II) complex in human fibrosarcoma cells.

Tardito S, Bussolati O, Gaccioli F, Gatti R, Guizzardi S, Uggeri J, Marchiò L, Lanfranchi M, Franchi-Gazzola R.

Histochem Cell Biol. 2006 Oct;126(4):473-82. Epub 2006 May 30.

PMID:
16733666
41.

Synthesis, solution equilibria and antiproliferative activity of copper(II) aminomethyltriazole and aminomethylthioxotriazoline complexes.

Gaccioli F, Franchi-Gazzola R, Lanfranchi M, Marchiò L, Metta G, Pellinghelli MA, Tardito S, Tegoni M.

J Inorg Biochem. 2005 Aug;99(8):1573-84.

PMID:
15953645

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