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Items: 13

1.

Nonimmune cell-derived ICOS ligand functions as a renoprotective αvβ3 integrin-selective antagonist.

Koh KH, Cao Y, Mangos S, Tardi NJ, Dande RR, Lee HW, Samelko B, Altintas MM, Schmitz VP, Lee H, Mukherjee K, Peev V, Cimbaluk DJ, Reiser J, Hahm E.

J Clin Invest. 2019 Apr 1;129(4):1713-1726. doi: 10.1172/JCI123386. Epub 2019 Mar 18.

2.

uPAR isoform 2 forms a dimer and induces severe kidney disease in mice.

Wei C, Li J, Adair BD, Zhu K, Cai J, Merchant M, Samelko B, Liao Z, Koh KH, Tardi NJ, Dande RR, Liu S, Ma J, Dibartolo S, Hägele S, Peev V, Hayek SS, Cimbaluk DJ, Tracy M, Klein J, Sever S, Shattil SJ, Arnaout MA, Reiser J.

J Clin Invest. 2019 Apr 2;130. pii: 124793. doi: 10.1172/JCI124793. eCollection 2019 Apr 2.

3.

Podocytes exhibit a specialized protein quality control employing derlin-2 in kidney disease.

Ren G, Tardi NJ, Matsuda F, Koh KH, Ruiz P, Wei C, Altintas MM, Ploegh H, Reiser J.

Am J Physiol Renal Physiol. 2018 Mar 1;314(3):F471-F482. doi: 10.1152/ajprenal.00691.2016. Epub 2017 Nov 22.

4.

A tripartite complex of suPAR, APOL1 risk variants and αvβ3 integrin on podocytes mediates chronic kidney disease.

Hayek SS, Koh KH, Grams ME, Wei C, Ko YA, Li J, Samelko B, Lee H, Dande RR, Lee HW, Hahm E, Peev V, Tracy M, Tardi NJ, Gupta V, Altintas MM, Garborcauskas G, Stojanovic N, Winkler CA, Lipkowitz MS, Tin A, Inker LA, Levey AS, Zeier M, Freedman BI, Kopp JB, Skorecki K, Coresh J, Quyyumi AA, Sever S, Reiser J.

Nat Med. 2017 Aug;23(8):945-953. doi: 10.1038/nm.4362. Epub 2017 Jun 26.

5.

Apoptosis and Compensatory Proliferation Signaling Are Coupled by CrkI-Containing Microvesicles.

Gupta KH, Goldufsky JW, Wood SJ, Tardi NJ, Moorthy GS, Gilbert DZ, Zayas JP, Hahm E, Altintas MM, Reiser J, Shafikhani SH.

Dev Cell. 2017 Jun 19;41(6):674-684.e5. doi: 10.1016/j.devcel.2017.05.014.

6.

The Use of Sildenafil for Glomerular Disease.

Tardi NJ, Reiser J.

J Am Soc Nephrol. 2017 May;28(5):1329-1331. doi: 10.1681/ASN.2017020171. Epub 2017 Mar 30. No abstract available.

7.

Bone marrow-derived immature myeloid cells are a main source of circulating suPAR contributing to proteinuric kidney disease.

Hahm E, Wei C, Fernandez I, Li J, Tardi NJ, Tracy M, Wadhwani S, Cao Y, Peev V, Zloza A, Lusciks J, Hayek SS, O'Connor C, Bitzer M, Gupta V, Sever S, Sykes DB, Scadden DT, Reiser J.

Nat Med. 2017 Jan;23(1):100-106. doi: 10.1038/nm.4242. Epub 2016 Dec 12.

8.

Absence of miR-146a in Podocytes Increases Risk of Diabetic Glomerulopathy via Up-regulation of ErbB4 and Notch-1.

Lee HW, Khan SQ, Khaliqdina S, Altintas MM, Grahammer F, Zhao JL, Koh KH, Tardi NJ, Faridi MH, Geraghty T, Cimbaluk DJ, Susztak K, Moita LF, Baltimore D, Tharaux PL, Huber TB, Kretzler M, Bitzer M, Reiser J, Gupta V.

J Biol Chem. 2017 Jan 13;292(2):732-747. doi: 10.1074/jbc.M116.753822. Epub 2016 Dec 2.

9.

A Podocyte-Based Automated Screening Assay Identifies Protective Small Molecules.

Lee HW, Khan SQ, Faridi MH, Wei C, Tardi NJ, Altintas MM, Elshabrawy HA, Mangos S, Quick KL, Sever S, Reiser J, Gupta V.

J Am Soc Nephrol. 2015 Nov;26(11):2741-52. doi: 10.1681/ASN.2014090859. Epub 2015 Apr 9.

10.

Controlled expression of Drosophila homeobox loci using the Hostile takeover system.

Javeed N, Tardi NJ, Maher M, Singari S, Edwards KA.

Dev Dyn. 2015 Jun;244(6):808-25. doi: 10.1002/dvdy.24279.

11.

Inducible protein traps with dominant phenotypes for functional analysis of the Drosophila genome.

Singari S, Javeed N, Tardi NJ, Marada S, Carlson JC, Kirk S, Thorn JM, Edwards KA.

Genetics. 2014 Jan;196(1):91-105. doi: 10.1534/genetics.113.157529. Epub 2013 Oct 30.

12.

Rapid phenotypic analysis of uncoated Drosophila samples with low-vacuum scanning electron microscopy.

Tardi NJ, Cook ME, Edwards KA.

Fly (Austin). 2012 Jul-Sep;6(3):184-92. doi: 10.4161/fly.20525. Epub 2012 Jun 22.

PMID:
22722327
13.

Comprehensive analysis of microRNA genomic loci identifies pervasive repetitive-element origins.

Borchert GM, Holton NW, Williams JD, Hernan WL, Bishop IP, Dembosky JA, Elste JE, Gregoire NS, Kim JA, Koehler WW, Lengerich JC, Medema AA, Nguyen MA, Ower GD, Rarick MA, Strong BN, Tardi NJ, Tasker NM, Wozniak DJ, Gatto C, Larson ED.

Mob Genet Elements. 2011 May;1(1):8-17.

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