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Items: 1 to 50 of 69

1.

GemC1 is a critical switch for neural stem cell generation in the postnatal brain.

Lalioti ME, Kaplani K, Lokka G, Georgomanolis T, Kyrousi C, Dong W, Dunbar A, Parlapani E, Damianidou E, Spassky N, Kahle KT, Papantonis A, Lygerou Z, Taraviras S.

Glia. 2019 Dec;67(12):2360-2373. doi: 10.1002/glia.23690. Epub 2019 Jul 22.

PMID:
31328313
2.

B cell depletion treatment decreases CD4+IL4+ and CD4+CD40L+ T cells in patients with systemic sclerosis.

Antonopoulos I, Daoussis D, Lalioti ME, Markatseli TE, Drosos AA, Taraviras S, Andonopoulos AP, Liossis SC.

Rheumatol Int. 2019 Nov;39(11):1889-1898. doi: 10.1007/s00296-019-04350-4. Epub 2019 Jun 21.

PMID:
31227855
3.

Replication Licensing Aberrations, Replication Stress, and Genomic Instability.

Petropoulos M, Champeris Tsaniras S, Taraviras S, Lygerou Z.

Trends Biochem Sci. 2019 Sep;44(9):752-764. doi: 10.1016/j.tibs.2019.03.011. Epub 2019 May 1. Review.

PMID:
31054805
4.

GemC1 governs multiciliogenesis through direct interaction with and transcriptional regulation of p73.

Lalioti ME, Arbi M, Loukas I, Kaplani K, Kalogeropoulou A, Lokka G, Kyrousi C, Mizi A, Georgomanolis T, Josipovic N, Gkikas D, Benes V, Politis PK, Papantonis A, Lygerou Z, Taraviras S.

J Cell Sci. 2019 Jun 3;132(11). pii: jcs228684. doi: 10.1242/jcs.228684.

PMID:
31028178
5.

Cortical Development and Brain Malformations: Insights From the Differential Regulation of Early Events of DNA Replication.

Kalogeropoulou A, Lygerou Z, Taraviras S.

Front Cell Dev Biol. 2019 Mar 11;7:29. doi: 10.3389/fcell.2019.00029. eCollection 2019. Review.

6.

Tobacco chemical-induced mouse lung adenocarcinoma cell lines pin the prolactin orthologue proliferin as a lung tumour promoter.

Kanellakis NI, Giannou AD, Pepe MA, Αgalioti T, Zazara DE, Giopanou I, Psallidas I, Spella M, Μarazioti A, Arendt KAM, Lamort AS, Tsaniras SC, Taraviras S, Papadaki H, Lilis I, Stathopoulos GT.

Carcinogenesis. 2019 Mar 4. pii: bgz047. doi: 10.1093/carcin/bgz047. [Epub ahead of print]

PMID:
30828726
7.

Adult Neural Stem Cells and Multiciliated Ependymal Cells Share a Common Lineage Regulated by the Geminin Family Members.

Ortiz-Álvarez G, Daclin M, Shihavuddin A, Lansade P, Fortoul A, Faucourt M, Clavreul S, Lalioti ME, Taraviras S, Hippenmeyer S, Livet J, Meunier A, Genovesio A, Spassky N.

Neuron. 2019 Apr 3;102(1):159-172.e7. doi: 10.1016/j.neuron.2019.01.051. Epub 2019 Feb 26.

8.

Direct binding of Cdt2 to PCNA is important for targeting the CRL4Cdt2 E3 ligase activity to Cdt1.

Hayashi A, Giakoumakis NN, Heidebrecht T, Ishii T, Panagopoulos A, Caillat C, Takahara M, Hibbert RG, Suenaga N, Stadnik-Spiewak M, Takahashi T, Shiomi Y, Taraviras S, von Castelmur E, Lygerou Z, Perrakis A, Nishitani H.

Life Sci Alliance. 2018 Dec 31;1(6):e201800238. doi: 10.26508/lsa.201800238. eCollection 2018 Dec.

9.

Visualizing the dynamics of histone variants in the S-phase nucleus.

Maxouri S, Taraviras S, Lygerou Z.

Genome Biol. 2018 Oct 31;19(1):182. doi: 10.1186/s13059-018-1556-4.

10.

Geminin ablation in vivo enhances tumorigenesis through increased genomic instability.

Champeris Tsaniras S, Villiou M, Giannou AD, Nikou S, Petropoulos M, Pateras IS, Tserou P, Karousi F, Lalioti ME, Gorgoulis VG, Patmanidi AL, Stathopoulos GT, Bravou V, Lygerou Z, Taraviras S.

J Pathol. 2018 Oct;246(2):134-140. doi: 10.1002/path.5128. Epub 2018 Aug 21.

PMID:
29952003
11.

EasyFRAP-web: a web-based tool for the analysis of fluorescence recovery after photobleaching data.

Koulouras G, Panagopoulos A, Rapsomaniki MA, Giakoumakis NN, Taraviras S, Lygerou Z.

Nucleic Acids Res. 2018 Jul 2;46(W1):W467-W472. doi: 10.1093/nar/gky508.

12.

Wound healing related agents: Ongoing research and perspectives.

Kaplani K, Koutsi S, Armenis V, Skondra FG, Karantzelis N, Champeris Tsaniras S, Taraviras S.

Adv Drug Deliv Rev. 2018 Apr;129:242-253. doi: 10.1016/j.addr.2018.02.007. Epub 2018 Mar 1. Review.

PMID:
29501699
13.

ILK Expression in Colorectal Cancer Is Associated with EMT, Cancer Stem Cell Markers and Chemoresistance.

Tsoumas D, Nikou S, Giannopoulou E, Champeris Tsaniras S, Sirinian C, Maroulis I, Taraviras S, Zolota V, Kalofonos HP, Bravou V.

Cancer Genomics Proteomics. 2018 Mar-Apr;15(2):127-141.

14.

Myeloid-derived interleukin-1β drives oncogenic KRAS-NF-κΒ addiction in malignant pleural effusion.

Marazioti A, Lilis I, Vreka M, Apostolopoulou H, Kalogeropoulou A, Giopanou I, Giotopoulou GA, Krontira AC, Iliopoulou M, Kanellakis NI, Agalioti T, Giannou AD, Jones-Paris C, Iwakura Y, Kardamakis D, Blackwell TS, Taraviras S, Spella M, Stathopoulos GT.

Nat Commun. 2018 Feb 14;9(1):672. doi: 10.1038/s41467-018-03051-z.

15.

Controlling centriole numbers: Geminin family members as master regulators of centriole amplification and multiciliogenesis.

Arbi M, Pefani DE, Taraviras S, Lygerou Z.

Chromosoma. 2018 Jun;127(2):151-174. doi: 10.1007/s00412-017-0652-7. Epub 2017 Dec 14. Review.

PMID:
29243212
16.

Geminin Participates in Differentiation Decisions of Adult Neural Stem Cells Transplanted in the Hemiparkinsonian Mouse Brain.

Taouki I, Tasiudi E, Lalioti ME, Kyrousi C, Skavatsou E, Kaplani K, Lygerou Z, Kouvelas ED, Mitsacos A, Giompres P, Taraviras S.

Stem Cells Dev. 2017 Aug 15;26(16):1214-1222. doi: 10.1089/scd.2016.0335. Epub 2017 Jun 30.

PMID:
28557659
17.

Mismatch repair regulates Cdt1 after UV damage.

Panagopoulos A, Taraviras S, Lygerou Z.

Cell Cycle. 2017 Jun 18;16(12):1143-1144. doi: 10.1080/15384101.2017.1319687. No abstract available.

18.

How a radial glial cell decides to become a multiciliated ependymal cell.

Kyrousi C, Lygerou Z, Taraviras S.

Glia. 2017 Jul;65(7):1032-1042. doi: 10.1002/glia.23118. Epub 2017 Feb 7. Review.

PMID:
28168763
19.

Simple in vitro generation of human leukocyte antigen-G-expressing T-regulatory cells through pharmacological hypomethylation for adoptive cellular immunotherapy against graft-versus-host disease.

Stamou P, Marioli D, Patmanidi AL, Sgourou A, Vittoraki A, Theofani E, Pierides C, Taraviras S, Costeas PA, Spyridonidis A.

Cytotherapy. 2017 Apr;19(4):521-530. doi: 10.1016/j.jcyt.2017.01.004. Epub 2017 Feb 2.

PMID:
28162915
20.

Concise Review: Geminin-A Tale of Two Tails: DNA Replication and Transcriptional/Epigenetic Regulation in Stem Cells.

Patmanidi AL, Champeris Tsaniras S, Karamitros D, Kyrousi C, Lygerou Z, Taraviras S.

Stem Cells. 2017 Feb;35(2):299-310. doi: 10.1002/stem.2529. Epub 2016 Nov 11. Review.

21.

Geminin prevents DNA damage in vagal neural crest cells to ensure normal enteric neurogenesis.

Konstantinidou C, Taraviras S, Pachnis V.

BMC Biol. 2016 Oct 24;14(1):94.

22.

Mcidas and GemC1/Lynkeas specify embryonic radial glial cells.

Kyrousi C, Lalioti ME, Skavatsou E, Lygerou Z, Taraviras S.

Neurogenesis (Austin). 2016 Apr 27;3(1):e1172747. doi: 10.1080/23262133.2016.1172747. eCollection 2016.

23.

Mammalian PNLDC1 is a novel poly(A) specific exonuclease with discrete expression during early development.

Anastasakis D, Skeparnias I, Shaukat AN, Grafanaki K, Kanellou A, Taraviras S, Papachristou DJ, Papakyriakou A, Stathopoulos C.

Nucleic Acids Res. 2016 Oct 14;44(18):8908-8920. Epub 2016 Aug 11.

24.

Whole transcriptome data analysis of mouse embryonic hematopoietic stem and progenitor cells that lack Geminin expression.

Patmanidi AL, Kanellakis NI, Karamitros D, Papadimitriou C, Lygerou Z, Taraviras S.

Data Brief. 2016 Mar 12;7:889-93. doi: 10.1016/j.dib.2016.03.028. eCollection 2016 Jun.

25.

GemC1 controls multiciliogenesis in the airway epithelium.

Arbi M, Pefani DE, Kyrousi C, Lalioti ME, Kalogeropoulou A, Papanastasiou AD, Taraviras S, Lygerou Z.

EMBO Rep. 2016 Mar;17(3):400-13. doi: 10.15252/embr.201540882. Epub 2016 Feb 4.

26.

Inactivation of Geminin in neural crest cells affects the generation and maintenance of enteric progenitor cells, leading to enteric aganglionosis.

Stathopoulou A, Natarajan D, Nikolopoulou P, Patmanidi AL, Lygerou Z, Pachnis V, Taraviras S.

Dev Biol. 2016 Jan 15;409(2):392-405. doi: 10.1016/j.ydbio.2015.11.023. Epub 2015 Dec 3.

27.

The structure of the GemC1 coiled coil and its interaction with the Geminin family of coiled-coil proteins.

Caillat C, Fish A, Pefani DE, Taraviras S, Lygerou Z, Perrakis A.

Acta Crystallogr D Biol Crystallogr. 2015 Nov;71(Pt 11):2278-86. doi: 10.1107/S1399004715016892. Epub 2015 Oct 31.

28.

Mcidas and GemC1 are key regulators for the generation of multiciliated ependymal cells in the adult neurogenic niche.

Kyrousi C, Arbi M, Pilz GA, Pefani DE, Lalioti ME, Ninkovic J, Götz M, Lygerou Z, Taraviras S.

Development. 2015 Nov 1;142(21):3661-74. doi: 10.1242/dev.126342. Epub 2015 Sep 22.

29.

Mast cells mediate malignant pleural effusion formation.

Giannou AD, Marazioti A, Spella M, Kanellakis NI, Apostolopoulou H, Psallidas I, Prijovich ZM, Vreka M, Zazara DE, Lilis I, Papaleonidopoulos V, Kairi CA, Patmanidi AL, Giopanou I, Spiropoulou N, Harokopos V, Aidinis V, Spyratos D, Teliousi S, Papadaki H, Taraviras S, Snyder LA, Eickelberg O, Kardamakis D, Iwakura Y, Feyerabend TB, Rodewald HR, Kalomenidis I, Blackwell TS, Agalioti T, Stathopoulos GT.

J Clin Invest. 2015 Jun;125(6):2317-34. doi: 10.1172/JCI79840. Epub 2015 Apr 27.

30.

Geminin deletion increases the number of fetal hematopoietic stem cells by affecting the expression of key transcription factors.

Karamitros D, Patmanidi AL, Kotantaki P, Potocnik AJ, Bähr-Ivacevic T, Benes V, Lygerou Z, Kioussis D, Taraviras S.

Development. 2015 Jan 1;142(1):70-81. doi: 10.1242/dev.109454.

31.

Licensing of DNA replication, cancer, pluripotency and differentiation: an interlinked world?

Champeris Tsaniras S, Kanellakis N, Symeonidou IE, Nikolopoulou P, Lygerou Z, Taraviras S.

Semin Cell Dev Biol. 2014 Jun;30:174-80. doi: 10.1016/j.semcdb.2014.03.013. Epub 2014 Mar 15. Review.

32.

Multi-step loading of human minichromosome maintenance proteins in live human cells.

Symeonidou IE, Kotsantis P, Roukos V, Rapsomaniki MA, Grecco HE, Bastiaens P, Taraviras S, Lygerou Z.

J Biol Chem. 2013 Dec 13;288(50):35852-67. doi: 10.1074/jbc.M113.474825. Epub 2013 Oct 24.

33.

The Geminin and Idas coiled coils preferentially form a heterodimer that inhibits Geminin function in DNA replication licensing.

Caillat C, Pefani DE, Gillespie PJ, Taraviras S, Blow JJ, Lygerou Z, Perrakis A.

J Biol Chem. 2013 Nov 1;288(44):31624-34. doi: 10.1074/jbc.M113.491928. Epub 2013 Sep 24.

34.

Cell cycle-dependent subcellular translocation of the human DNA licensing inhibitor geminin.

Dimaki M, Xouri G, Symeonidou IE, Sirinian C, Nishitani H, Taraviras S, Lygerou Z.

J Biol Chem. 2013 Aug 16;288(33):23953-63. doi: 10.1074/jbc.M113.453092. Epub 2013 Jun 29.

35.

Reduced Geminin levels promote cellular senescence.

Iliou MS, Kotantaki P, Karamitros D, Spella M, Taraviras S, Lygerou Z.

Mech Ageing Dev. 2013 Jan-Feb;134(1-2):10-23. doi: 10.1016/j.mad.2012.10.001. Epub 2012 Nov 8.

PMID:
23142824
36.

Neural stem cells transplanted in a mouse model of Parkinson's disease differentiate to neuronal phenotypes and reduce rotational deficit.

Ziavra D, Makri G, Giompres P, Taraviras S, Thomaidou D, Matsas R, Mitsacos A, Kouvelas ED.

CNS Neurol Disord Drug Targets. 2012 Nov 1;11(7):829-35.

PMID:
23131156
37.

Control over DNA replication in time and space.

Symeonidou IE, Taraviras S, Lygerou Z.

FEBS Lett. 2012 Aug 31;586(18):2803-12. doi: 10.1016/j.febslet.2012.07.042. Epub 2012 Jul 25. Review.

38.

easyFRAP: an interactive, easy-to-use tool for qualitative and quantitative analysis of FRAP data.

Rapsomaniki MA, Kotsantis P, Symeonidou IE, Giakoumakis NN, Taraviras S, Lygerou Z.

Bioinformatics. 2012 Jul 1;28(13):1800-1. doi: 10.1093/bioinformatics/bts241. Epub 2012 Apr 27.

PMID:
22543368
39.

Cdt1 is differentially targeted for degradation by anticancer chemotherapeutic drugs.

Stathopoulou A, Roukos V, Petropoulou C, Kotsantis P, Karantzelis N, Nishitani H, Lygerou Z, Taraviras S.

PLoS One. 2012;7(3):e34621. doi: 10.1371/journal.pone.0034621. Epub 2012 Mar 30.

40.

T cell proliferation and homeostasis: an emerging role for the cell cycle inhibitor geminin.

Karamitros D, Kotantaki P, Lygerou Z, Kioussis D, Taraviras S.

Crit Rev Immunol. 2011;31(3):209-31. Review.

PMID:
21740351
41.

Geminin regulates cortical progenitor proliferation and differentiation.

Spella M, Kyrousi C, Kritikou E, Stathopoulou A, Guillemot F, Kioussis D, Pachnis V, Lygerou Z, Taraviras S.

Stem Cells. 2011 Aug;29(8):1269-82. doi: 10.1002/stem.678.

42.

Idas, a novel phylogenetically conserved geminin-related protein, binds to geminin and is required for cell cycle progression.

Pefani DE, Dimaki M, Spella M, Karantzelis N, Mitsiki E, Kyrousi C, Symeonidou IE, Perrakis A, Taraviras S, Lygerou Z.

J Biol Chem. 2011 Jul 1;286(26):23234-46. doi: 10.1074/jbc.M110.207688. Epub 2011 May 4.

43.

Age and visual experience-dependent expression of NMDAR1 splice variants in rat retina.

Manta G, Spathis AD, Taraviras S, Kouvelas ED, Mitsacos A.

Neurochem Res. 2011 Aug;36(8):1417-25. doi: 10.1007/s11064-011-0467-5. Epub 2011 Apr 16.

PMID:
21499738
44.

Dynamic recruitment of licensing factor Cdt1 to sites of DNA damage.

Roukos V, Kinkhabwala A, Colombelli J, Kotsantis P, Taraviras S, Nishitani H, Stelzer E, Bastiaens P, Lygerou Z.

J Cell Sci. 2011 Feb 1;124(Pt 3):422-34. doi: 10.1242/jcs.074229. Epub 2011 Jan 11.

45.

Self-renewal mechanisms in neural cancer stem cells.

Mantamadiotis T, Taraviras S.

Front Biosci (Landmark Ed). 2011 Jan 1;16:598-607. Review.

PMID:
21196191
46.

Life without geminin.

Karamitros D, Kotantaki P, Lygerou Z, Veiga-Fernandes H, Pachnis V, Kioussis D, Taraviras S.

Cell Cycle. 2010 Aug 15;9(16):3181-5. doi: 10.4161/cc.9.16.12554. Epub 2010 Aug 28.

47.

Differential geminin requirement for proliferation of thymocytes and mature T cells.

Karamitros D, Kotantaki P, Lygerou Z, Veiga-Fernandes H, Pachnis V, Kioussis D, Taraviras S.

J Immunol. 2010 Mar 1;184(5):2432-41. doi: 10.4049/jimmunol.0901983. Epub 2010 Jan 27.

48.

Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing.

De Marco V, Gillespie PJ, Li A, Karantzelis N, Christodoulou E, Klompmaker R, van Gerwen S, Fish A, Petoukhov MV, Iliou MS, Lygerou Z, Medema RH, Blow JJ, Svergun DI, Taraviras S, Perrakis A.

Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):19807-12. doi: 10.1073/pnas.0905281106. Epub 2009 Nov 11.

49.

Cdt1 and Geminin in cancer: markers or triggers of malignant transformation?

Petropoulou C, Kotantaki P, Karamitros D, Taraviras S.

Front Biosci. 2008 May 1;13:4485-94. Review.

PMID:
18508524
50.

Deregulated overexpression of hCdt1 and hCdc6 promotes malignant behavior.

Liontos M, Koutsami M, Sideridou M, Evangelou K, Kletsas D, Levy B, Kotsinas A, Nahum O, Zoumpourlis V, Kouloukoussa M, Lygerou Z, Taraviras S, Kittas C, Bartkova J, Papavassiliou AG, Bartek J, Halazonetis TD, Gorgoulis VG.

Cancer Res. 2007 Nov 15;67(22):10899-909.

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