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Items: 1 to 50 of 125

1.

Long-term health of women with genetic POI due to FSH resistant ovaries.

Luiro K, Aittomaki K, Jousilahti P, Tapanainen JS.

Endocr Connect. 2019 Sep 1. pii: EC-19-0244.R2. doi: 10.1530/EC-19-0244. [Epub ahead of print]

2.

Metformin decreases bone turnover markers in polycystic ovary syndrome: a post hoc study.

Lingaiah S, Morin-Papunen L, Risteli J, Tapanainen JS.

Fertil Steril. 2019 Aug;112(2):362-370. doi: 10.1016/j.fertnstert.2019.04.013. Epub 2019 Jun 18.

PMID:
31227287
3.

Serum retinol-binding protein 4 levels in polycystic ovary syndrome.

Lingaiah S, Morin-Papunen L, Piltonen T, Sundström-Poromaa I, Stener-Victorin E, Tapanainen JS.

Endocr Connect. 2019 Jun 1;8(6):709-717. doi: 10.1530/EC-19-0116.

4.

The effect of length of birth interval on the risk of breast cancer by subtype in grand multiparous women.

Katuwal S, Tapanainen JS, Pukkala E, Kauppila A.

BMC Cancer. 2019 Mar 4;19(1):199. doi: 10.1186/s12885-019-5404-z.

5.

Age at adiposity rebound in childhood is associated with PCOS diagnosis and obesity in adulthood-longitudinal analysis of BMI data from birth to age 46 in cases of PCOS.

Koivuaho E, Laru J, Ojaniemi M, Puukka K, Kettunen J, Tapanainen JS, Franks S, Järvelin MR, Morin-Papunen L, Sebert S, Piltonen TT.

Int J Obes (Lond). 2019 Jul;43(7):1370-1379. doi: 10.1038/s41366-019-0318-z. Epub 2019 Feb 4.

6.

Hormone profiling, including anti-Müllerian hormone (AMH), for the diagnosis of polycystic ovary syndrome (PCOS) and characterization of PCOS phenotypes.

Sova H, Unkila-Kallio L, Tiitinen A, Hippeläinen M, Perheentupa A, Tinkanen H, Puukka K, Bloigu R, Piltonen T, Tapanainen JS, Morin-Papunen L.

Gynecol Endocrinol. 2019 Jul;35(7):595-600. doi: 10.1080/09513590.2018.1559807. Epub 2019 Jan 22.

PMID:
30668196
7.

Circulating antimüllerian hormone and steroid hormone levels remain high in pregnant women with polycystic ovary syndrome at term.

Piltonen TT, Giacobini P, Edvinsson Å, Hustad S, Lager S, Morin-Papunen L, Tapanainen JS, Sundström-Poromaa I, Arffman RK.

Fertil Steril. 2019 Mar;111(3):588-596.e1. doi: 10.1016/j.fertnstert.2018.11.028. Epub 2019 Jan 7.

8.

Self-Reported Polycystic Ovary Syndrome Is Associated With Hypertension: A Northern Finland Birth Cohort 1966 Study.

Ollila ME, Kaikkonen K, Järvelin MR, Huikuri HV, Tapanainen JS, Franks S, Piltonen TT, Morin-Papunen L.

J Clin Endocrinol Metab. 2019 Apr 1;104(4):1221-1231. doi: 10.1210/jc.2018-00570.

PMID:
30445634
9.

Demographic and evolutionary trends in ovarian function and aging.

Laisk T, Tšuiko O, Jatsenko T, Hõrak P, Otala M, Lahdenperä M, Lummaa V, Tuuri T, Salumets A, Tapanainen JS.

Hum Reprod Update. 2019 Jan 1;25(1):34-50. doi: 10.1093/humupd/dmy031.

PMID:
30346539
10.

Hyperglycosylated hCG activates LH/hCG-receptor with lower activity than hCG.

Koistinen H, Koel M, Peters M, Rinken A, Lundin K, Tuuri T, Tapanainen JS, Alfthan H, Salumets A, Stenman UH, Lavogina D.

Mol Cell Endocrinol. 2019 Jan 5;479:103-109. doi: 10.1016/j.mce.2018.09.006. Epub 2018 Oct 2.

11.

Advances in the Molecular Pathophysiology, Genetics, and Treatment of Primary Ovarian Insufficiency.

Huhtaniemi I, Hovatta O, La Marca A, Livera G, Monniaux D, Persani L, Heddar A, Jarzabek K, Laisk-Podar T, Salumets A, Tapanainen JS, Veitia RA, Visser JA, Wieacker P, Wolczynski S, Misrahi M.

Trends Endocrinol Metab. 2018 Jun;29(6):400-419. doi: 10.1016/j.tem.2018.03.010. Epub 2018 Apr 26. Review.

12.

The Long-Term Footprint of Endometriosis: Population-Based Cohort Analysis Reveals Increased Pain Symptoms and Decreased Pain Tolerance at Age 46 Years.

Vuontisjärvi S, Rossi HR, Herrala S, Morin-Papunen L, Tapanainen JS, Karjula S, Karppinen J, Auvinen J, Piltonen TT.

J Pain. 2018 Jul;19(7):754-763. doi: 10.1016/j.jpain.2018.02.005. Epub 2018 Mar 2.

PMID:
29496639
13.

A missense mutation in SLC26A3 is associated with human male subfertility and impaired activation of CFTR.

Wedenoja S, Khamaysi A, Shimshilashvili L, Anbtawe-Jomaa S, Elomaa O, Toppari J, Höglund P, Aittomäki K, Holmberg C, Hovatta O, Tapanainen JS, Ohana E, Kere J.

Sci Rep. 2017 Oct 27;7(1):14208. doi: 10.1038/s41598-017-14606-3.

14.

The prevalence of Type 2 diabetes is not increased in normal-weight women with PCOS.

Pelanis R, Mellembakken JR, Sundström-Poromaa I, Ravn P, Morin-Papunen L, Tapanainen JS, Piltonen T, Puurunen J, Hirschberg AL, Fedorcsak P, Andersen M, Glintborg D.

Hum Reprod. 2017 Nov 1;32(11):2279-2286. doi: 10.1093/humrep/dex294.

PMID:
29040530
15.

The Role of Sequential BMP Signaling in Directing Human Embryonic Stem Cells to Bipotential Gonadal Cells.

Sepponen K, Lundin K, Knuus K, Väyrynen P, Raivio T, Tapanainen JS, Tuuri T.

J Clin Endocrinol Metab. 2017 Nov 1;102(11):4303-4314. doi: 10.1210/jc.2017-01469.

PMID:
28938435
16.

Bone markers in polycystic ovary syndrome: A multicentre study.

Lingaiah S, Morin-Papunen L, Piltonen T, Puurunen J, Sundström-Poromaa I, Stener-Victorin E, Bloigu R, Risteli J, Tapanainen JS.

Clin Endocrinol (Oxf). 2017 Dec;87(6):673-679. doi: 10.1111/cen.13456. Epub 2017 Sep 21.

PMID:
28845895
17.

Testosterone is associated with insulin resistance index independently of adiposity in women with polycystic ovary syndrome.

Luotola K, Piltonen TT, Puurunen J, Morin-Papunen LC, Tapanainen JS.

Gynecol Endocrinol. 2018 Jan;34(1):40-44. doi: 10.1080/09513590.2017.1342793. Epub 2017 Jul 5.

PMID:
28678568
18.

Niche matters: The comparison between bone marrow stem cells and endometrial stem cells and stromal fibroblasts reveal distinct migration and cytokine profiles in response to inflammatory stimulus.

Khatun M, Sorjamaa A, Kangasniemi M, Sutinen M, Salo T, Liakka A, Lehenkari P, Tapanainen JS, Vuolteenaho O, Chen JC, Lehtonen S, Piltonen TT.

PLoS One. 2017 Apr 18;12(4):e0175986. doi: 10.1371/journal.pone.0175986. eCollection 2017.

19.

Racial and ethnic differences in the prevalence of metabolic syndrome and its components of metabolic syndrome in women with polycystic ovary syndrome: a regional cross-sectional study.

Chan JL, Kar S, Vanky E, Morin-Papunen L, Piltonen T, Puurunen J, Tapanainen JS, Maciel GAR, Hayashida SAY, Soares JM Jr, Baracat EC, Mellembakken JR, Dokras A.

Am J Obstet Gynecol. 2017 Aug;217(2):189.e1-189.e8. doi: 10.1016/j.ajog.2017.04.007. Epub 2017 Apr 8.

PMID:
28400308
20.

Overweight and obese but not normal weight women with PCOS are at increased risk of Type 2 diabetes mellitus-a prospective population-based cohort study.

Ollila MM, West S, Keinänen-Kiukaaniemi S, Jokelainen J, Auvinen J, Puukka K, Ruokonen A, Järvelin MR, Tapanainen JS, Franks S, Piltonen TT, Morin-Papunen LC.

Hum Reprod. 2017 Apr 1;32(4):968. doi: 10.1093/humrep/dex030. No abstract available.

21.

Psychological Distress Is More Prevalent in Fertile Age and Premenopausal Women With PCOS Symptoms: 15-Year Follow-Up.

Karjula S, Morin-Papunen L, Auvinen J, Ruokonen A, Puukka K, Franks S, Järvelin MR, Tapanainen JS, Jokelainen J, Miettunen J, Piltonen TT.

J Clin Endocrinol Metab. 2017 Jun 1;102(6):1861-1869. doi: 10.1210/jc.2016-3863.

22.

Determination of biological activity of gonadotropins hCG and FSH by Förster resonance energy transfer based biosensors.

Mazina O, Allikalt A, Tapanainen JS, Salumets A, Rinken A.

Sci Rep. 2017 Feb 9;7:42219. doi: 10.1038/srep42219.

23.

Should we individualize lipid profiling in women with polycystic ovary syndrome?

Poromaa IS, Mellembakken JR, Morin-Papunen L, Piltonen T, Puurenen J, Tapanainen JS, Stener-Victorin E, Hirschberg AL, Vanky E, Ravn P, Glintborg D, Andersen M.

Hum Reprod. 2017 Apr 1;32(4):966. doi: 10.1093/humrep/dex009. No abstract available.

PMID:
28175322
24.

Normo- and hyperandrogenic women with polycystic ovary syndrome exhibit an adverse metabolic profile through life.

Pinola P, Puukka K, Piltonen TT, Puurunen J, Vanky E, Sundström-Poromaa I, Stener-Victorin E, Lindén Hirschberg A, Ravn P, Skovsager Andersen M, Glintborg D, Mellembakken JR, Ruokonen A, Tapanainen JS, Morin-Papunen LC.

Fertil Steril. 2017 Mar;107(3):788-795.e2. doi: 10.1016/j.fertnstert.2016.12.017. Epub 2017 Jan 12.

PMID:
28089571
25.

Overweight and obese but not normal weight women with PCOS are at increased risk of Type 2 diabetes mellitus-a prospective, population-based cohort study.

Ollila MM, West S, Keinänen-Kiukaanniemi S, Jokelainen J, Auvinen J, Puukka K, Ruokonen A, Järvelin MR, Tapanainen JS, Franks S, Piltonen TT, Morin-Papunen LC.

Hum Reprod. 2017 Feb;32(2):423-431. doi: 10.1093/humrep/dew329. Epub 2016 Dec 28. Erratum in: Hum Reprod. 2017 Apr 1;32(4):968.

26.

Should we individualize lipid profiling in women with polycystic ovary syndrome?

Sundström Poromaa I, Mellembakken JR, Morin-Papunen L, Piltonen T, Puurunen J, Tapanainen JS, Stener-Victorin E, Hirschberg AL, Vanky E, Ravn P, Glintborg D, Andersen M.

Hum Reprod. 2016 Dec;31(12):2791-2795. Epub 2016 Sep 22. Erratum in: Hum Reprod. 2017 Apr 1;32(4):966.

PMID:
27664213
27.

Copy number variation analysis detects novel candidate genes involved in follicular growth and oocyte maturation in a cohort of premature ovarian failure cases.

Tšuiko O, Nõukas M, Žilina O, Hensen K, Tapanainen JS, Mägi R, Kals M, Kivistik PA, Haller-Kikkatalo K, Salumets A, Kurg A.

Hum Reprod. 2016 Aug;31(8):1913-25. doi: 10.1093/humrep/dew142. Epub 2016 Jun 14.

28.

Functional Expression of FSH Receptor in Endometriotic Lesions.

Ponikwicka-Tyszko D, Chrusciel M, Stelmaszewska J, Bernaczyk P, Sztachelska M, Sidorkiewicz I, Doroszko M, Tomaszewski J, Tapanainen JS, Huhtaniemi I, Wolczynski S, Rahman NA.

J Clin Endocrinol Metab. 2016 Jul;101(7):2905-14. doi: 10.1210/jc.2016-1014. Epub 2016 May 25.

PMID:
27224263
29.

Ovarian Physiology and GWAS: Biobanks, Biology, and Beyond.

Laisk-Podar T, Lindgren CM, Peters M, Tapanainen JS, Lambalk CB, Salumets A, Mägi R.

Trends Endocrinol Metab. 2016 Jul;27(7):516-528. doi: 10.1016/j.tem.2016.04.011. Epub 2016 May 21. Review.

PMID:
27221566
30.

IL-1 receptor antagonist levels are associated with glucose tolerance in polycystic ovary syndrome.

Luotola K, Piltonen TT, Puurunen J, Tapanainen JS.

Clin Endocrinol (Oxf). 2016 Sep;85(3):430-5. doi: 10.1111/cen.13077. Epub 2016 Apr 26.

PMID:
27061312
31.

Weight Gain and Dyslipidemia in Early Adulthood Associate With Polycystic Ovary Syndrome: Prospective Cohort Study.

Ollila MM, Piltonen T, Puukka K, Ruokonen A, Järvelin MR, Tapanainen JS, Franks S, Morin-Papunen L.

J Clin Endocrinol Metab. 2016 Feb;101(2):739-47. doi: 10.1210/jc.2015-3543. Epub 2015 Dec 10.

32.

Incidence of cancer among grand multiparous women in Finland with special focus on non-gynaecological cancers: A population-based cohort study.

Högnäs E, Kauppila A, Hinkula M, Tapanainen JS, Pukkala E.

Acta Oncol. 2016;55(3):370-6. doi: 10.3109/0284186X.2015.1063775. Epub 2015 Jul 28.

PMID:
26217985
33.

Androgen Profile Through Life in Women With Polycystic Ovary Syndrome: A Nordic Multicenter Collaboration Study.

Pinola P, Piltonen TT, Puurunen J, Vanky E, Sundström-Poromaa I, Stener-Victorin E, Ruokonen A, Puukka K, Tapanainen JS, Morin-Papunen LC.

J Clin Endocrinol Metab. 2015 Sep;100(9):3400-7. doi: 10.1210/jc.2015-2123. Epub 2015 Jul 20.

PMID:
26192874
34.

The effect of atorvastatin treatment on serum oxysterol concentrations and cytochrome P450 3A4 activity.

Hukkanen J, Puurunen J, Hyötyläinen T, Savolainen MJ, Ruokonen A, Morin-Papunen L, Orešič M, Piltonen T, Tapanainen JS.

Br J Clin Pharmacol. 2015 Sep;80(3):473-9. doi: 10.1111/bcp.12701. Epub 2015 Jul 22.

35.

The clinical utility of serum anti-Müllerian hormone in the follow-up of ovarian adult-type granulosa cell tumors--A comparative study with inhibin B.

Färkkilä A, Koskela S, Bryk S, Alfthan H, Bützow R, Leminen A, Puistola U, Tapanainen JS, Heikinheimo M, Anttonen M, Unkila-Kallio L.

Int J Cancer. 2015 Oct 1;137(7):1661-71. doi: 10.1002/ijc.29532. Epub 2015 Apr 11.

36.

Effect of controlled hypoglycaemia on sympathetic skin response in patients with Type 1 diabetes and control subjects.

Koivikko ML, Airaksinen KE, Perkiömäki JS, Huikuri HV, Tapanainen JS, Kallio MA.

Diabet Med. 2015 Apr;32(4):556-60. doi: 10.1111/dme.12619. Epub 2015 Jan 23.

PMID:
25346161
37.

Irregular menstruation and hyperandrogenaemia in adolescence are associated with polycystic ovary syndrome and infertility in later life: Northern Finland Birth Cohort 1986 study.

West S, Lashen H, Bloigu A, Franks S, Puukka K, Ruokonen A, Järvelin MR, Tapanainen JS, Morin-Papunen L.

Hum Reprod. 2014 Oct 10;29(10):2339-51. doi: 10.1093/humrep/deu200. Epub 2014 Aug 1.

38.

Anti-Müllerian hormone: correlation with testosterone and oligo- or amenorrhoea in female adolescence in a population-based cohort study.

Pinola P, Morin-Papunen LC, Bloigu A, Puukka K, Ruokonen A, Järvelin MR, Franks S, Tapanainen JS, Lashen H.

Hum Reprod. 2014 Oct 10;29(10):2317-25. doi: 10.1093/humrep/deu182. Epub 2014 Jul 23.

39.

Cancer risk in women with 10 or more deliveries.

Högnäs E, Kauppila A, Pukkala E, Tapanainen JS.

Obstet Gynecol. 2014 Apr;123(4):811-6. doi: 10.1097/AOG.0000000000000182.

PMID:
24785609
40.

Serum sex hormone-binding globulin and testosterone in relation to cardiovascular disease risk factors in young men: a population-based study.

Canoy D, Barber TM, Pouta A, Hartikainen AL, McCarthy MI, Franks S, Järvelin MR, Tapanainen JS, Ruokonen A, Huhtaniemi IT, Martikainen H.

Eur J Endocrinol. 2014 Jun;170(6):863-72. doi: 10.1530/EJE-13-1046. Epub 2014 Mar 26.

PMID:
24670886
41.

Statin therapy worsens insulin sensitivity in women with polycystic ovary syndrome (PCOS): a prospective, randomized, double-blind, placebo-controlled study.

Puurunen J, Piltonen T, Puukka K, Ruokonen A, Savolainen MJ, Bloigu R, Morin-Papunen L, Tapanainen JS.

J Clin Endocrinol Metab. 2013 Dec;98(12):4798-807. doi: 10.1210/jc.2013-2674. Epub 2013 Oct 23.

PMID:
24152688
42.

Factors affecting the outcome of frozen-thawed embryo transfer.

Veleva Z, Orava M, Nuojua-Huttunen S, Tapanainen JS, Martikainen H.

Hum Reprod. 2013 Sep;28(9):2425-31. doi: 10.1093/humrep/det251. Epub 2013 Jun 11.

PMID:
23756705
43.

Masculinization of the eruption pattern of permanent mandibular canines in opposite sex twin girls.

Heikkinen T, Harila V, Tapanainen JS, Alvesalo L.

Am J Phys Anthropol. 2013 Aug;151(4):566-72. doi: 10.1002/ajpa.22298. Epub 2013 Jun 11.

PMID:
23754587
44.

Research resource: small RNA-seq of human granulosa cells reveals miRNAs in FSHR and aromatase genes.

Velthut-Meikas A, Simm J, Tuuri T, Tapanainen JS, Metsis M, Salumets A.

Mol Endocrinol. 2013 Jul;27(7):1128-41. doi: 10.1210/me.2013-1058. Epub 2013 May 9.

45.

Antimüllerian hormone levels decrease in women using combined contraception independently of administration route.

Kallio S, Puurunen J, Ruokonen A, Vaskivuo T, Piltonen T, Tapanainen JS.

Fertil Steril. 2013 Apr;99(5):1305-10. doi: 10.1016/j.fertnstert.2012.11.034. Epub 2012 Dec 20.

PMID:
23260855
46.

Oral, transdermal and vaginal combined contraceptives induce an increase in markers of chronic inflammation and impair insulin sensitivity in young healthy normal-weight women: a randomized study.

Piltonen T, Puurunen J, Hedberg P, Ruokonen A, Mutt SJ, Herzig KH, Nissinen A, Morin-Papunen L, Tapanainen JS.

Hum Reprod. 2012 Oct;27(10):3046-56. doi: 10.1093/humrep/des225. Epub 2012 Jul 18.

PMID:
22811306
47.

Metformin improves pregnancy and live-birth rates in women with polycystic ovary syndrome (PCOS): a multicenter, double-blind, placebo-controlled randomized trial.

Morin-Papunen L, Rantala AS, Unkila-Kallio L, Tiitinen A, Hippeläinen M, Perheentupa A, Tinkanen H, Bloigu R, Puukka K, Ruokonen A, Tapanainen JS.

J Clin Endocrinol Metab. 2012 May;97(5):1492-500. doi: 10.1210/jc.2011-3061. Epub 2012 Mar 14.

PMID:
22419702
48.

Anti-Mullerian hormone as a predictor of follicular reserve in ovarian insufficiency: special emphasis on FSH-resistant ovaries.

Kallio S, Aittomäki K, Piltonen T, Veijola R, Liakka A, Vaskivuo TE, Dunkel L, Tapanainen JS.

Hum Reprod. 2012 Mar;27(3):854-60. doi: 10.1093/humrep/der473. Epub 2012 Jan 17.

PMID:
22258659
49.

Full-length visfatin levels are associated with inflammation in women with polycystic ovary syndrome.

Lajunen TK, Purhonen AK, Haapea M, Ruokonen A, Puukka K, Hartikainen AL, Savolainen MJ, Morin-Papunen L, Tapanainen JS, Franks S, Järvelin MR, Herzig KH.

Eur J Clin Invest. 2012 Mar;42(3):321-8. doi: 10.1111/j.1365-2362.2011.02586.x. Epub 2011 Sep 13.

PMID:
21913913
50.

Unfavorable hormonal, metabolic, and inflammatory alterations persist after menopause in women with PCOS.

Puurunen J, Piltonen T, Morin-Papunen L, Perheentupa A, Järvelä I, Ruokonen A, Tapanainen JS.

J Clin Endocrinol Metab. 2011 Jun;96(6):1827-34. doi: 10.1210/jc.2011-0039. Epub 2011 Mar 30.

PMID:
21450988

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