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Items: 1 to 50 of 106

1.

BPR1M97, a dual mu opioid receptor/nociceptin-orphanin FQ peptide receptor agonist, produces potent antinociceptive effects with safer properties than morphine.

Chao PK, Chang HF, Chang WT, Yeh TK, Ou LC, Chuang JY, Tsu-An Hsu J, Tao PL, Loh HH, Shih C, Ueng SH, Yeh SH.

Neuropharmacology. 2019 Jul 3:107678. doi: 10.1016/j.neuropharm.2019.107678. [Epub ahead of print]

PMID:
31278929
2.

Delta-opioid receptor antagonist naltrindole reduces oxycodone addiction and constipation in mice.

Yang PP, Yeh TK, Loh HH, Law PY, Wang Y, Tao PL.

Eur J Pharmacol. 2019 Jun 5;852:265-273. doi: 10.1016/j.ejphar.2019.04.009. Epub 2019 Apr 6.

PMID:
30959048
3.

Convallatoxin enhance the ligand-induced mu-opioid receptor endocytosis and attenuate morphine antinociceptive tolerance in mice.

Chao PK, Chang HF, Ou LC, Chuang JY, Lee PT, Chang WT, Chen SC, Ueng SH, Hsu JT, Tao PL, Law PY, Loh HH, Yeh SH.

Sci Rep. 2019 Feb 20;9(1):2405. doi: 10.1038/s41598-019-39555-x.

4.

The in vivo antinociceptive and μ-opioid receptor activating effects of the combination of N-phenyl-2',4'-dimethyl-4,5'-bi-1,3-thiazol-2-amines and naloxone.

Lin SY, Kuo YH, Tien YW, Ke YY, Chang WT, Chang HF, Ou LC, Law PY, Xi JH, Tao PL, Loh HH, Chao YS, Shih C, Chen CT, Yeh SH, Ueng SH.

Eur J Med Chem. 2019 Apr 1;167:312-323. doi: 10.1016/j.ejmech.2019.01.063. Epub 2019 Feb 2.

PMID:
30776693
5.

1-(2,4-Dibromophenyl)-3,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indazol-4-one: A Novel Opioid Receptor Agonist with Less Accompanying Gastrointestinal Dysfunction than Morphine.

Chao PK, Ueng SH, Ou LC, Yeh TK, Chang WT, Chang HF, Chen SC, Tao PL, Law PY, Loh HH, Cheng MF, Chuang JY, Chen CT, Shih C, Yeh SH.

Anesthesiology. 2017 May;126(5):952-966. doi: 10.1097/ALN.0000000000001568.

PMID:
28212204
6.

Reply to: Agonism at delta-opioid receptor contributes to the antinociceptive effect of oxycodone in mice.

Tao PL.

Pharmacol Res. 2016 Dec;114:293. doi: 10.1016/j.phrs.2016.10.013. Epub 2016 Oct 21. No abstract available.

PMID:
27777132
7.

Activation of delta-opioid receptor contributes to the antinociceptive effect of oxycodone in mice.

Yang PP, Yeh GC, Yeh TK, Xi J, Loh HH, Law PY, Tao PL.

Pharmacol Res. 2016 Sep;111:867-876. doi: 10.1016/j.phrs.2016.05.034. Epub 2016 Aug 2.

PMID:
27496654
8.

Delayed extinction and stronger drug-primed reinstatement of methamphetamine seeking in rats prenatally exposed to morphine.

Shen YL, Chen ST, Chan TY, Hung TW, Tao PL, Liao RM, Chan MH, Chen HH.

Neurobiol Learn Mem. 2016 Feb;128:56-64. doi: 10.1016/j.nlm.2015.12.002. Epub 2015 Dec 29.

PMID:
26743042
9.

Angiotensin IV possibly acts through PKMzeta in the hippocampus to regulate cognitive memory in rats.

Chow LH, Tao PL, Chen YH, Lin YH, Huang EY.

Neuropeptides. 2015 Oct;53:1-10. doi: 10.1016/j.npep.2015.09.004. Epub 2015 Sep 14.

PMID:
26412453
10.

Effects of dextromethorphan and oxycodone on treatment of neuropathic pain in mice.

Yang PP, Yeh GC, Huang EY, Law PY, Loh HH, Tao PL.

J Biomed Sci. 2015 Sep 22;22:81. doi: 10.1186/s12929-015-0186-3.

11.

Beneficial effects of co-treatment with dextromethorphan on prenatally methadone-exposed offspring.

Chiang YC, Ye LC, Hsu KY, Liao CW, Hung TW, Lo WJ, Ho IK, Tao PL.

J Biomed Sci. 2015 Mar 20;22:19. doi: 10.1186/s12929-015-0126-2.

12.

A novel literature-based approach to identify genetic and molecular predictors of survival in glioblastoma multiforme: Analysis of 14,678 patients using systematic review and meta-analytical tools.

Thuy MN, Kam JK, Lee GC, Tao PL, Ling DQ, Cheng M, Goh SK, Papachristos AJ, Shukla L, Wall KL, Smoll NR, Jones JJ, Gikenye N, Soh B, Moffat B, Johnson N, Drummond KJ.

J Clin Neurosci. 2015 May;22(5):785-99. doi: 10.1016/j.jocn.2014.10.029. Epub 2015 Feb 16. Review.

PMID:
25698544
13.

Genetics and pharmacogenetics of substance use disorders.

Tao PL, Chen LS, Chen CK, Liu YL.

J Food Drug Anal. 2013 Dec;21(4):S23-S24.

14.

Effect of naltrexone on neuropathic pain in mice locally transfected with the mutant μ-opioid receptor gene in spinal cord.

Kao JH, Gao MJ, Yang PP, Law PY, Loh HH, Tao PL.

Br J Pharmacol. 2015 Jan;172(2):630-41. doi: 10.1111/bph.12790.

15.
16.

Mu-opioid receptor knockout mice are more sensitive to chlordiazepoxide-induced anxiolytic behavior.

Wang KC, Lee YJ, Fan LW, Yang PP, Tao PL, Ho IK, Tien LT.

Brain Res Bull. 2013 Jan;90:137-41. doi: 10.1016/j.brainresbull.2012.10.009. Epub 2012 Nov 8.

PMID:
23142328
17.

A possible correlation between oxytocin-induced and angiotensin IV-induced anti-hyperalgesia at the spinal level in rats.

Chow LH, Tao PL, Chen JC, Liao RM, Chang EP, Huang EY.

Peptides. 2013 Jan;39:21-8. doi: 10.1016/j.peptides.2012.10.012. Epub 2012 Nov 8.

PMID:
23142109
18.

Dextromethorphan attenuated inflammation and combined opioid use in humans undergoing methadone maintenance treatment.

Chen SL, Lee SY, Tao PL, Chang YH, Chen SH, Chu CH, Chen PS, Lee IH, Yeh TL, Yang YK, Hong JS, Lu RB.

J Neuroimmune Pharmacol. 2012 Dec;7(4):1025-33. doi: 10.1007/s11481-012-9400-1. Epub 2012 Sep 19.

PMID:
22990619
19.

p53 acts as a co-repressor to regulate keratin 14 expression during epidermal cell differentiation.

Cai BH, Hsu PC, Hsin IL, Chao CF, Lu MH, Lin HC, Chiou SH, Tao PL, Chen JY.

PLoS One. 2012;7(7):e41742. doi: 10.1371/journal.pone.0041742. Epub 2012 Jul 24.

20.

Resveratrol regulates N-methyl-D-aspartate receptor expression and suppresses neuroinflammation in morphine-tolerant rats.

Tsai RY, Chou KY, Shen CH, Chien CC, Tsai WY, Huang YN, Tao PL, Lin YS, Wong CS.

Anesth Analg. 2012 Oct;115(4):944-52. Epub 2012 Jun 19.

PMID:
22713680
21.

Post-treatment of dextromethorphan on methamphetamine-induced drug-seeking and behavioral sensitization in rats.

Yang PP, Huang EY, Fu YY, Ho TS, Tao PL.

Synapse. 2012 Oct;66(10):858-69. doi: 10.1002/syn.21576. Epub 2012 Jun 26.

PMID:
22674496
22.

LVV-hemorphin 7 and angiotensin IV in correlation with antinociception and anti-thermal hyperalgesia in rats.

Cheng BC, Tao PL, Cheng YY, Huang EY.

Peptides. 2012 Jul;36(1):9-16. doi: 10.1016/j.peptides.2012.03.019. Epub 2012 Mar 29.

PMID:
22484286
23.
24.

Low-dose memantine attenuated morphine addictive behavior through its anti-inflammation and neurotrophic effects in rats.

Chen SL, Tao PL, Chu CH, Chen SH, Wu HE, Tseng LF, Hong JS, Lu RB.

J Neuroimmune Pharmacol. 2012 Jun;7(2):444-53. doi: 10.1007/s11481-011-9337-9. Epub 2011 Dec 29.

25.

Intrathecal ultra-low dose naloxone enhances the antinociceptive effect of morphine by enhancing the reuptake of excitatory amino acids from the synaptic cleft in the spinal cord of partial sciatic nerve-transected rats.

Yang CP, Cherng CH, Wu CT, Huang HY, Tao PL, Wong CS.

Anesth Analg. 2011 Dec;113(6):1490-500. doi: 10.1213/ANE.0b013e31822d39c1. Epub 2011 Aug 24.

PMID:
21865493
26.
27.

NR2B subunit of NMDA receptor at nucleus accumbens is involved in morphine rewarding effect by siRNA study.

Kao JH, Huang EY, Tao PL.

Drug Alcohol Depend. 2011 Nov 1;118(2-3):366-74. doi: 10.1016/j.drugalcdep.2011.04.019. Epub 2011 May 23.

PMID:
21601998
28.

Low doses of dextromethorphan attenuate morphine-induced rewarding via the sigma-1 receptor at ventral tegmental area in rats.

Chen SL, Hsu KY, Huang EY, Lu RB, Tao PL.

Drug Alcohol Depend. 2011 Sep 1;117(2-3):164-9. doi: 10.1016/j.drugalcdep.2011.01.013. Epub 2011 Feb 12.

PMID:
21320758
29.

A possible association of the norepinephrine transporter gene in the development of heroin dependence in Han Chinese.

Yeh YW, Lu RB, Tao PL, Shih MC, Huang SY.

Pharmacogenet Genomics. 2011 Apr;21(4):197-205. doi: 10.1097/FPC.0b013e32833ef418.

PMID:
20818294
30.

Intrathecal delivery of a mutant micro-opioid receptor activated by naloxone as a possible antinociceptive paradigm.

Kao JH, Chen SL, Ma HI, Law PY, Tao PL, Loh HH.

J Pharmacol Exp Ther. 2010 Sep 1;334(3):739-45. doi: 10.1124/jpet.109.165399. Epub 2010 Jun 16.

31.

Prenatal exposure to methamphetamine alters the mechanical withdrawal threshold and tonic hyperalgesia in the offspring.

Chen JY, Yeh GC, Tao PL, Kuo CT, Chen KB, Wen YR.

Neurotoxicology. 2010 Sep;31(5):432-8. doi: 10.1016/j.neuro.2010.06.002. Epub 2010 Jun 12.

PMID:
20547178
32.

Neither single-marker nor haplotype analyses support an association between the dopamine transporter gene and heroin dependence in Han Chinese.

Yeh YW, Lu RB, Tao PL, Shih MC, Lin WW, Huang SY.

Genes Brain Behav. 2010 Aug;9(6):638-47. doi: 10.1111/j.1601-183X.2010.00597.x. Epub 2010 May 20.

33.

Antinociceptive effects of morphine and naloxone in mu-opioid receptor knockout mice transfected with the MORS196A gene.

Chen SL, Ma HI, Han JM, Lu RB, Tao PL, Law PY, Loh HH.

J Biomed Sci. 2010 Apr 20;17:28. doi: 10.1186/1423-0127-17-28.

34.

Distribution of neuropeptide FF (NPFF) receptors in correlation with morphine-induced reward in the rat brain.

Wu CH, Tao PL, Huang EY.

Peptides. 2010 Jul;31(7):1374-82. doi: 10.1016/j.peptides.2010.03.036. Epub 2010 Apr 8.

PMID:
20381562
35.

Search for the "ideal analgesic" in pain treatment by engineering the mu-opioid receptor.

Tao PL, Law PY, Loh HH.

IUBMB Life. 2010 Feb;62(2):103-11. doi: 10.1002/iub.292. Review.

36.
37.

Decoy receptor 3 ameliorates experimental autoimmune encephalomyelitis by directly counteracting local inflammation and downregulating Th17 cells.

Chen SJ, Wang YL, Kao JH, Wu SF, Lo WT, Wu CC, Tao PL, Wang CC, Chang DM, Sytwu HK.

Mol Immunol. 2009 Dec;47(2-3):567-74. doi: 10.1016/j.molimm.2009.09.017. Epub 2009 Oct 12.

PMID:
19819554
38.

Amitriptyline suppresses neuroinflammation-dependent interleukin-10-p38 mitogen-activated protein kinase-heme oxygenase-1 signaling pathway in chronic morphine-infused rats.

Tai YH, Tsai RY, Lin SL, Yeh CC, Wang JJ, Tao PL, Wong CS.

Anesthesiology. 2009 Jun;110(6):1379-89. doi: 10.1097/ALN.0b013e31819fccd5.

PMID:
19417613
39.

Coadministration of dextromethorphan during pregnancy and throughout lactation prevents morphine-induced hyperprolactinemia in female rats.

Wu LY, Huang EY, Tao PL.

Fertil Steril. 2010 Mar 15;93(5):1686-94. doi: 10.1016/j.fertnstert.2009.01.143. Epub 2009 Mar 26.

PMID:
19324339
40.

Overexpression of Thellungiella halophila H(+)-PPase (TsVP) in cotton enhances drought stress resistance of plants.

Lv SL, Lian LJ, Tao PL, Li ZX, Zhang KW, Zhang JR.

Planta. 2009 Mar;229(4):899-910. doi: 10.1007/s00425-008-0880-4. Epub 2009 Jan 8.

PMID:
19130078
41.

Prenatal morphine alters the synaptic complex of postsynaptic density 95 with N-methyl-D-aspartate receptor subunit in hippocampal CA1 subregion of rat offspring leading to long-term cognitive deficits.

Lin CS, Tao PL, Jong YJ, Chen WF, Yang CH, Huang LT, Chao CF, Yang SN.

Neuroscience. 2009 Feb 18;158(4):1326-37. doi: 10.1016/j.neuroscience.2008.11.007. Epub 2008 Nov 8.

PMID:
19041927
42.

Amitriptyline induces nuclear transcription factor-kappaB-dependent glutamate transporter upregulation in chronic morphine-infused rats.

Tai YH, Tsai RY, Wang YH, Cherng CH, Tao PL, Liu TM, Wong CS.

Neuroscience. 2008 May 15;153(3):823-31. doi: 10.1016/j.neuroscience.2008.02.055. Epub 2008 Mar 6.

PMID:
18400403
43.

dsAAV type 2-mediated gene transfer of MORS196A-EGFP into spinal cord as a pain management paradigm.

Chen SL, Ma HI, Han JM, Tao PL, Law PY, Loh HH.

Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):20096-101. Epub 2007 Dec 4.

44.

Post-treatment of dextromethorphan reverses morphine effect on conditioned place preference in rats.

Lue WM, Huang EY, Yang SN, Wong CS, Tao PL.

Synapse. 2007 Jun;61(6):420-8.

PMID:
17372963
45.
46.

Co-administration of dextromethorphan with methamphetamine attenuates methamphetamine-induced rewarding and behavioral sensitization.

Yang PP, Huang EY, Yeh GC, Tao PL.

J Biomed Sci. 2006 Sep;13(5):695-702. Epub 2006 Jul 23.

PMID:
16865411
47.
48.

Amitriptyline suppresses neuroinflammation and up-regulates glutamate transporters in morphine-tolerant rats.

Tai YH, Wang YH, Wang JJ, Tao PL, Tung CS, Wong CS.

Pain. 2006 Sep;124(1-2):77-86. Epub 2006 May 11.

PMID:
16697108
49.

Alterations of postsynaptic density proteins in the hippocampus of rat offspring from the morphine-addicted mother: Beneficial effect of dextromethorphan.

Yang SN, Liu CA, Chung MY, Huang HC, Yeh GC, Wong CS, Lin WW, Yang CH, Tao PL.

Hippocampus. 2006;16(6):521-30.

PMID:
16598705
50.

Nalbuphine is effective in decreasing the rewarding effect induced by morphine in rats.

Tao PL, Liang KW, Sung WY, Wu YT, Huang EY.

Drug Alcohol Depend. 2006 Sep 15;84(2):175-81. Epub 2006 Mar 6.

PMID:
16517095

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