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Items: 1 to 50 of 222

1.

Characterization of the human E2F4 promoter region and its response to 12-O-tetradecanoylphorbol-13-acetate.

Hamada H, Goto Y, Arakawa J, Murayama E, Ogawa Y, Konno M, Oyama T, Asai M, Sato A, Tanuma SI, Uchiumi F.

J Biochem. 2019 Jun 14. pii: mvz047. doi: 10.1093/jb/mvz047. [Epub ahead of print]

PMID:
31199460
2.

Targeting poly(ADP-ribose) glycohydrolase to draw apoptosis codes in cancer.

Tanuma SI, Shibui Y, Oyama T, Uchiumi F, Abe H.

Biochem Pharmacol. 2019 Jun 6. pii: S0006-2952(19)30223-0. doi: 10.1016/j.bcp.2019.06.004. [Epub ahead of print] Review.

PMID:
31176615
3.

Structure-based drug design of novel carborane-containing nicotinamide phosphoribosyltransferase inhibitors.

Asawa Y, Katsuragi K, Sato A, Yoshimori A, Tanuma SI, Nakamura H.

Bioorg Med Chem. 2019 Jul 1;27(13):2832-2844. doi: 10.1016/j.bmc.2019.05.013. Epub 2019 May 10.

PMID:
31103405
4.

Anticancer effects of a non-narcotic opium alkaloid medicine, papaverine, in human glioblastoma cells.

Inada M, Shindo M, Kobayashi K, Sato A, Yamamoto Y, Akasaki Y, Ichimura K, Tanuma SI.

PLoS One. 2019 May 17;14(5):e0216358. doi: 10.1371/journal.pone.0216358. eCollection 2019.

5.

Papaverine identified as an inhibitor of high mobility group box 1/receptor for advanced glycation end-products interaction suppresses high mobility group box 1-mediated inflammatory responses.

Tamada K, Nakajima S, Ogawa N, Inada M, Shibasaki H, Sato A, Takasawa R, Yoshimori A, Suzuki Y, Watanabe N, Oyama T, Abe H, Inoue S, Abe T, Yokomizo T, Tanuma S.

Biochem Biophys Res Commun. 2019 Apr 9;511(3):665-670. doi: 10.1016/j.bbrc.2019.01.136. Epub 2019 Feb 27.

PMID:
30826057
6.

Characterization of a novel microRNA, miR-188, elevated in serum of muscular dystrophy dog model.

Shibasaki H, Imamura M, Arima S, Tanihata J, Kuraoka M, Matsuzaka Y, Uchiumi F, Tanuma SI, Takeda S.

PLoS One. 2019 Jan 30;14(1):e0211597. doi: 10.1371/journal.pone.0211597. eCollection 2019.

7.

Genomic and tumor biological aspects of the anticancer nicotinamide phosphoribosyltransferase inhibitor FK866 in resistant human colorectal cancer cells.

Ogino Y, Sato A, Uchiumi F, Tanuma SI.

Genomics. 2018 Dec 21. pii: S0888-7543(18)30663-3. doi: 10.1016/j.ygeno.2018.12.012. [Epub ahead of print]

PMID:
30582964
8.

Glyoxalase 1 gene is highly expressed in basal-like human breast cancers and contributes to survival of ALDH1-positive breast cancer stem cells.

Tamori S, Nozaki Y, Motomura H, Nakane H, Katayama R, Onaga C, Kikuchi E, Shimada N, Suzuki Y, Noike M, Hara Y, Sato K, Sato T, Yamamoto K, Hanawa T, Imai M, Abe R, Yoshimori A, Takasawa R, Tanuma SI, Akimoto K.

Oncotarget. 2018 Nov 23;9(92):36515-36529. doi: 10.18632/oncotarget.26369. eCollection 2018 Nov 23.

9.

TRPV4 Channel-Regulated ATP Release Contributes to γ-Irradiation-Induced Production of IL-6 and IL-8 in Epidermal Keratinocytes.

Ohsaki A, Tanuma SI, Tsukimoto M.

Biol Pharm Bull. 2018 Oct 1;41(10):1620-1626. doi: 10.1248/bpb.b18-00361. Epub 2018 Jul 19.

10.

Cross resistance to diverse anticancer nicotinamide phosphoribosyltransferase inhibitors induced by FK866 treatment.

Ogino Y, Sato A, Uchiumi F, Tanuma SI.

Oncotarget. 2018 Mar 27;9(23):16451-16461. doi: 10.18632/oncotarget.24731. eCollection 2018 Mar 27.

11.

A Novel Mechanism of γ-Irradiation-Induced IL-6 Production Mediated by P2Y11 Receptor in Epidermal Keratinocytes.

Ohsaki A, Miyano Y, Tanaka R, Tanuma SI, Kojima S, Tsukimoto M.

Biol Pharm Bull. 2018 Jun 1;41(6):925-936. doi: 10.1248/bpb.b18-00075. Epub 2018 Mar 16.

12.

In vitro anticancer effects of a RAGE inhibitor discovered using a structure-based drug design system.

El-Far AHAM, Munesue S, Harashima A, Sato A, Shindo M, Nakajima S, Inada M, Tanaka M, Takeuchi A, Tsuchiya H, Yamamoto H, Shaheen HME, El-Sayed YS, Kawano S, Tanuma SI, Yamamoto Y.

Oncol Lett. 2018 Apr;15(4):4627-4634. doi: 10.3892/ol.2018.7902. Epub 2018 Jan 29.

13.

Interdependence of GLO I and PKM2 in the Metabolic shift to escape apoptosis in GLO I-dependent cancer cells.

Shimada N, Takasawa R, Tanuma SI.

Arch Biochem Biophys. 2018 Jan 15;638:1-7. doi: 10.1016/j.abb.2017.12.008. Epub 2017 Dec 8.

PMID:
29225125
14.

Correlation between c-Met and ALDH1 contributes to the survival and tumor-sphere formation of ALDH1 positive breast cancer stem cells and predicts poor clinical outcome in breast cancer.

Nozaki Y, Tamori S, Inada M, Katayama R, Nakane H, Minamishima O, Onodera Y, Abe M, Shiina S, Tamura K, Kodama D, Sato K, Hara Y, Abe R, Takasawa R, Yoshimori A, Shinomiya N, Tanuma SI, Akimoto K.

Genes Cancer. 2017 Jul;8(7-8):628-639. doi: 10.18632/genesandcancer.148.

15.

Calculations of Electron Inelastic Mean Free Paths. XI. Data for Liquid Water for Energies from 50 eV to 30 keV.

Shinotsuka H, Da B, Tanuma S, Yoshikawa H, Powell CJ, Penn DR.

Surf Interface Anal. 2017 Apr;49(4):238-252. doi: 10.1002/sia.6123. Epub 2017 Mar 16.

16.

Virtual substrate method for nanomaterials characterization.

Da B, Liu J, Yamamoto M, Ueda Y, Watanabe K, Cuong NT, Li S, Tsukagoshi K, Yoshikawa H, Iwai H, Tanuma S, Guo H, Gao Z, Sun X, Ding Z.

Nat Commun. 2017 May 26;8:15629. doi: 10.1038/ncomms15629.

17.

Structural insight into the active site of mushroom tyrosinase using phenylbenzoic acid derivatives.

Oyama T, Yoshimori A, Takahashi S, Yamamoto T, Sato A, Kamiya T, Abe H, Abe T, Tanuma SI.

Bioorg Med Chem Lett. 2017 Jul 1;27(13):2868-2872. doi: 10.1016/j.bmcl.2017.04.074. Epub 2017 Apr 26.

PMID:
28495084
18.

Impact of Acetazolamide, a Carbonic Anhydrase Inhibitor, on the Development of Intestinal Polyps in Min Mice.

Noma N, Fujii G, Miyamoto S, Komiya M, Nakanishi R, Shimura M, Tanuma SI, Mutoh M.

Int J Mol Sci. 2017 Apr 17;18(4). pii: E851. doi: 10.3390/ijms18040851.

19.

Radiosensitizing Effect of P2X7 Receptor Antagonist on Melanoma in Vitro and in Vivo.

Tanamachi K, Nishino K, Mori N, Suzuki T, Tanuma SI, Abe R, Tsukimoto M.

Biol Pharm Bull. 2017 Jun 1;40(6):878-887. doi: 10.1248/bpb.b17-00083. Epub 2017 Mar 24.

20.

Piceatannol, a natural trans-stilbene compound, inhibits human glyoxalase I.

Takasawa R, Akahane H, Tanaka H, Shimada N, Yamamoto T, Uchida-Maruki H, Sai M, Yoshimori A, Tanuma SI.

Bioorg Med Chem Lett. 2017 Mar 1;27(5):1169-1174. doi: 10.1016/j.bmcl.2017.01.070. Epub 2017 Jan 25.

PMID:
28169168
21.

Differences in the effects of four TRPV1 channel antagonists on lipopolysaccharide-induced cytokine production and COX-2 expression in murine macrophages.

Ninomiya Y, Tanuma SI, Tsukimoto M.

Biochem Biophys Res Commun. 2017 Mar 11;484(3):668-674. doi: 10.1016/j.bbrc.2017.01.173. Epub 2017 Jan 31.

PMID:
28153725
22.

Cationic Amphiphilic Tris-Cyclometalated Iridium(III) Complexes Induce Cancer Cell Death via Interaction with Ca2+-Calmodulin Complex.

Hisamatsu Y, Suzuki N, Masum AA, Shibuya A, Abe R, Sato A, Tanuma SI, Aoki S.

Bioconjug Chem. 2017 Feb 15;28(2):507-523. doi: 10.1021/acs.bioconjchem.6b00627. Epub 2016 Dec 29.

PMID:
28032992
23.

New Insights into the Roles of NAD+-Poly(ADP-ribose) Metabolism and Poly(ADP-ribose) Glycohydrolase.

Tanuma S, Sato A, Oyama T, Yoshimori A, Abe H, Uchiumi F.

Curr Protein Pept Sci. 2016;17(7):668-682. Review.

PMID:
27817743
24.

Discovery of a new type of scaffold for the creation of novel tyrosinase inhibitors.

Oyama T, Takahashi S, Yoshimori A, Yamamoto T, Sato A, Kamiya T, Abe H, Abe T, Tanuma SI.

Bioorg Med Chem. 2016 Sep 15;24(18):4509-4515. doi: 10.1016/j.bmc.2016.07.060. Epub 2016 Jul 28.

PMID:
27507110
25.

Silica nanoparticles activate purinergic signaling via P2X7 receptor in dendritic cells, leading to production of pro-inflammatory cytokines.

Nakanishi K, Tsukimoto M, Tanuma S, Takeda K, Kojima S.

Toxicol In Vitro. 2016 Sep;35:202-11. doi: 10.1016/j.tiv.2016.06.003. Epub 2016 Jun 14.

PMID:
27311643
26.

Radiosensitizing Effect of TRPV1 Channel Inhibitors in Cancer Cells.

Nishino K, Tanamachi K, Nakanishi Y, Ide S, Kojima S, Tanuma S, Tsukimoto M.

Biol Pharm Bull. 2016 Jul 1;39(7):1224-30. doi: 10.1248/bpb.b16-00080. Epub 2016 May 3.

27.

TLSC702, a Novel Inhibitor of Human Glyoxalase I, Induces Apoptosis in Tumor Cells.

Takasawa R, Shimada N, Uchiro H, Takahashi S, Yoshimori A, Tanuma S.

Biol Pharm Bull. 2016;39(5):869-73. doi: 10.1248/bpb.b15-00710.

28.

Characterization of the 5'-flanking region of the human DNA helicase B (HELB) gene and its response to trans-Resveratrol.

Uchiumi F, Arakawa J, Iwakoshi K, Ishibashi S, Tanuma S.

Sci Rep. 2016 Apr 15;6:24510. doi: 10.1038/srep24510.

29.

MicroRNA-351 Regulates Two-Types of Cell Death, Necrosis and Apoptosis, Induced by 5-fluoro-2'-deoxyuridine.

Sato A, Omi T, Yamamoto A, Satake A, Hiramoto A, Masutani M, Tanuma S, Wataya Y, Kim HS.

PLoS One. 2016 Apr 12;11(4):e0153130. doi: 10.1371/journal.pone.0153130. eCollection 2016.

30.

Determination of the catalytic activity of LEOPARD syndrome-associated SHP2 mutants toward parafibromin, a bona fide SHP2 substrate involved in Wnt signaling.

Noda S, Takahashi A, Hayashi T, Tanuma S, Hatakeyama M.

Biochem Biophys Res Commun. 2016 Jan 22;469(4):1133-9. doi: 10.1016/j.bbrc.2015.12.117. Epub 2015 Dec 29.

PMID:
26742426
31.

Characterization of the 5'-flanking region of the human TP53 gene and its response to the natural compound, Resveratrol.

Uchiumi F, Shoji K, Sasaki Y, Sasaki M, Sasaki Y, Oyama T, Sugisawa K, Tanuma S.

J Biochem. 2016 Apr;159(4):437-47. doi: 10.1093/jb/mvv126. Epub 2015 Dec 17.

32.

The hematopoietic regulator, ELF-1, enhances the transcriptional response to Interferon-β of the OAS1 anti-viral gene.

Larsen S, Kawamoto S, Tanuma S, Uchiumi F.

Sci Rep. 2015 Dec 8;5:17497. doi: 10.1038/srep17497.

33.

Effects of 3-styrylchromones on metabolic profiles and cell death in oral squamous cell carcinoma cells.

Sakagami H, Shimada C, Kanda Y, Amano O, Sugimoto M, Ota S, Soga T, Tomita M, Sato A, Tanuma SI, Takao K, Sugita Y.

Toxicol Rep. 2015 Dec 4;2:1281-1290. doi: 10.1016/j.toxrep.2015.09.009. eCollection 2015.

34.

Extracellular ATP induces P2X7 receptor activation in mouse Kupffer cells, leading to release of IL-1β, HMGB1, and PGE2, decreased MHC class I expression and necrotic cell death.

Toki Y, Takenouchi T, Harada H, Tanuma S, Kitani H, Kojima S, Tsukimoto M.

Biochem Biophys Res Commun. 2015 Mar 20;458(4):771-6. doi: 10.1016/j.bbrc.2015.02.011. Epub 2015 Feb 11.

PMID:
25681768
35.

Transcriptional regulation of Tal2 gene by all-trans retinoic acid (atRA) in P19 cells.

Kobayashi T, Suzuki M, Morikawa M, Kino K, Tanuma S, Miyazawa H.

Biol Pharm Bull. 2015;38(2):248-56. doi: 10.1248/bpb.b14-00617. Epub 2014 Dec 5.

36.

Structure-activity relationships of the thujaplicins for inhibition of human tyrosinase.

Yoshimori A, Oyama T, Takahashi S, Abe H, Kamiya T, Abe T, Tanuma S.

Bioorg Med Chem. 2014 Nov 1;22(21):6193-200. doi: 10.1016/j.bmc.2014.08.027. Epub 2014 Sep 21.

PMID:
25288494
37.

[Application of DEAE-dextran method to an efficient gene transfer system].

Uchiumi F, Ohi H, Tanuma S.

Seikagaku. 2014 Aug;86(4):532-7. Japanese. No abstract available.

PMID:
25255642
38.

Extended Mermin method for calculating the electron inelastic mean free path.

Da B, Shinotsuka H, Yoshikawa H, Ding ZJ, Tanuma S.

Phys Rev Lett. 2014 Aug 8;113(6):063201. Epub 2014 Aug 7.

PMID:
25148325
39.

Tal2 expression is induced by all-trans retinoic acid in P19 cells prior to acquisition of neural fate.

Kobayashi T, Komori R, Ishida K, Kino K, Tanuma S, Miyazawa H.

Sci Rep. 2014 May 12;4:4935. doi: 10.1038/srep04935.

40.

A gain-of-function screen to identify genes that reduce lifespan in the adult of Drosophila melanogaster.

Nakayama M, Ishibashi T, Ishikawa HO, Sato H, Usui T, Okuda T, Yashiro H, Ishikawa H, Taikou Y, Minami A, Kato K, Taki M, Aigaki T, Gunji W, Ohtsu M, Murakami Y, Tanuma S, Tsuboi A, Adachi M, Kuroda J, Sasamura T, Yamakawa T, Matsuno K.

BMC Genet. 2014 Apr 16;15:46. doi: 10.1186/1471-2156-15-46.

41.

DNase γ is the effector endonuclease for internucleosomal DNA fragmentation in necrosis.

Mizuta R, Araki S, Furukawa M, Furukawa Y, Ebara S, Shiokawa D, Hayashi K, Tanuma S, Kitamura D.

PLoS One. 2013 Dec 2;8(12):e80223. doi: 10.1371/journal.pone.0080223. eCollection 2013.

42.

PARP1 gene expression is downregulated by knockdown of PARG gene.

Uchiumi F, Watanabe T, Ohta R, Abe H, Tanuma S.

Oncol Rep. 2013 May;29(5):1683-8. doi: 10.3892/or.2013.2321. Epub 2013 Mar 4.

43.

CHK1 cleavage in programmed cell death is intricately regulated by both caspase and non-caspase family proteases.

Okita N, Yoshimura M, Watanabe K, Minato S, Kudo Y, Higami Y, Tanuma S.

Biochim Biophys Acta. 2013 Jan;1830(1):2204-13. doi: 10.1016/j.bbagen.2012.10.009. Epub 2012 Oct 16.

PMID:
23085068
44.

DNA damage-induced CHK1 autophosphorylation at Ser296 is regulated by an intramolecular mechanism.

Okita N, Minato S, Ohmi E, Tanuma S, Higami Y.

FEBS Lett. 2012 Nov 16;586(22):3974-9. doi: 10.1016/j.febslet.2012.09.048. Epub 2012 Oct 12.

45.

Novel compound SK-1009 suppresses interleukin-6 expression through modulation of activation of nuclear factor-kappaB pathway.

Shimura M, Yamamoto M, Fujii G, Takahashi M, Komiya M, Noma N, Tanuma S, Yanaka A, Mutoh M.

Biol Pharm Bull. 2012;35(12):2186-91. Epub 2012 Sep 27.

46.

[Biological functions of the duplicated GGAA-motifs in various human promoter regions].

Uchiumi F, Miyazaki S, Tanuma S.

Yakugaku Zasshi. 2011;131(12):1787-800. Review.

47.

Structure-based design of dipeptide derivatives for the human neutral endopeptidase.

Misawa K, Suzuki Y, Takahashi S, Yoshimori A, Takasawa R, Shibuya Y, Tanuma S.

Bioorg Med Chem. 2011 Oct 15;19(20):5935-47. doi: 10.1016/j.bmc.2011.08.064. Epub 2011 Sep 1.

PMID:
21937235
48.

Cladribine enhances apoptotic cell death in lung carcinoma cells over-expressing DNase γ.

Hayakawa A, Suzuki H, Kamei Y, Tanuma S, Magae J.

Biol Pharm Bull. 2011;34(7):1001-4.

49.

Discovery of a new type inhibitor of human glyoxalase I by myricetin-based 4-point pharmacophore.

Takasawa R, Tao A, Saeki K, Shionozaki N, Tanaka R, Uchiro H, Takahashi S, Yoshimori A, Tanuma S.

Bioorg Med Chem Lett. 2011 Jul 15;21(14):4337-42. doi: 10.1016/j.bmcl.2011.05.046. Epub 2011 May 23.

PMID:
21669529
50.

The possible functions of duplicated ets (GGAA) motifs located near transcription start sites of various human genes.

Uchiumi F, Miyazaki S, Tanuma S.

Cell Mol Life Sci. 2011 Jun;68(12):2039-51. doi: 10.1007/s00018-011-0674-x. Epub 2011 Apr 3.

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