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Items: 1 to 50 of 52

1.

Investigation of Seizure-Susceptibility in a Drosophila melanogaster Model of Human Epilepsy with Optogenetic Stimulation.

Saras A, Wu VV, Brawer HJ, Tanouye MA.

Genetics. 2017 Aug;206(4):1739-1746. doi: 10.1534/genetics.116.194779. Epub 2017 Jun 19.

2.

Seizure Suppression by High Temperature via cAMP Modulation in Drosophila.

Saras A, Tanouye MA.

G3 (Bethesda). 2016 Oct 13;6(10):3381-3387. doi: 10.1534/g3.116.034629.

3.

Mutations of the Calcium Channel Gene cacophony Suppress Seizures in Drosophila.

Saras A, Tanouye MA.

PLoS Genet. 2016 Jan 15;12(1):e1005784. doi: 10.1371/journal.pgen.1005784. eCollection 2016 Jan. Erratum in: PLoS Genet. 2016 Feb;12(2):e1005871.

4.

Disruption of Endocytosis with the Dynamin Mutant shibirets1 Suppresses Seizures in Drosophila.

Kroll JR, Wong KG, Siddiqui FM, Tanouye MA.

Genetics. 2015 Nov;201(3):1087-102. doi: 10.1534/genetics.115.177600. Epub 2015 Sep 4.

5.

Drosophila sodium channel mutations: Contributions to seizure-susceptibility.

Kroll JR, Saras A, Tanouye MA.

Exp Neurol. 2015 Dec;274(Pt A):80-7. doi: 10.1016/j.expneurol.2015.06.018. Epub 2015 Jun 18. Review.

6.

Modeling glial contributions to seizures and epileptogenesis: cation-chloride cotransporters in Drosophila melanogaster.

Rusan ZM, Kingsford OA, Tanouye MA.

PLoS One. 2014 Jun 27;9(6):e101117. doi: 10.1371/journal.pone.0101117. eCollection 2014. Erratum in: PLoS One. 2014;9(9):e108081.

7.

Seizure-sensitivity in Drosophila is ameliorated by dorsal vessel injection of the antiepileptic drug valproate.

Howlett IC, Tanouye MA.

J Neurogenet. 2013 Dec;27(4):143-50. doi: 10.3109/01677063.2013.817574. Epub 2013 Aug 14.

PMID:
23941042
8.

Drosophila as a model for intractable epilepsy: gilgamesh suppresses seizures in para(bss1) heterozygote flies.

Howlett IC, Rusan ZM, Parker L, Tanouye MA.

G3 (Bethesda). 2013 Aug 7;3(8):1399-407. doi: 10.1534/g3.113.006130.

9.

Rescue of easily shocked mutant seizure sensitivity in Drosophila adults.

Kroll JR, Tanouye MA.

J Comp Neurol. 2013 Oct 15;521(15):3500-7. doi: 10.1002/cne.23364.

10.

Seizure and epilepsy: studies of seizure disorders in Drosophila.

Parker L, Howlett IC, Rusan ZM, Tanouye MA.

Int Rev Neurobiol. 2011;99:1-21. doi: 10.1016/B978-0-12-387003-2.00001-X. Review.

11.

Drosophila as a model for epilepsy: bss is a gain-of-function mutation in the para sodium channel gene that leads to seizures.

Parker L, Padilla M, Du Y, Dong K, Tanouye MA.

Genetics. 2011 Feb;187(2):523-34. doi: 10.1534/genetics.110.123299. Epub 2010 Nov 29.

12.

Seizure sensitivity is ameliorated by targeted expression of K+-Cl- cotransporter function in the mushroom body of the Drosophila brain.

Hekmat-Scafe DS, Mercado A, Fajilan AA, Lee AW, Hsu R, Mount DB, Tanouye MA.

Genetics. 2010 Jan;184(1):171-83. doi: 10.1534/genetics.109.109074. Epub 2009 Nov 2.

13.

Neurocircuit assays for seizures in epilepsy mutants of Drosophila.

Howlett IC, Tanouye MA.

J Vis Exp. 2009 Apr 15;(26). pii: 1121. doi: 10.3791/1121.

14.

DNA topoisomerase I inhibitors ameliorate seizure-like behaviors and paralysis in a Drosophila model of epilepsy.

Song J, Parker L, Hormozi L, Tanouye MA.

Neuroscience. 2008 Oct 15;156(3):722-8. doi: 10.1016/j.neuroscience.2008.07.024. Epub 2008 Jul 23.

15.

Seymour Benzer 1921-2007.

Tanouye MA.

Nat Genet. 2008 Feb;40(2):121. doi: 10.1038/ng0208-121. No abstract available.

16.

From bench to drug: human seizure modeling using Drosophila.

Song J, Tanouye MA.

Prog Neurobiol. 2008 Feb;84(2):182-91. Epub 2007 Oct 26. Review.

17.

Mutations in the K+/Cl- cotransporter gene kazachoc (kcc) increase seizure susceptibility in Drosophila.

Hekmat-Scafe DS, Lundy MY, Ranga R, Tanouye MA.

J Neurosci. 2006 Aug 30;26(35):8943-54.

18.

Drosophila homolog of APP-BP1 (dAPP-BP1) interacts antagonistically with APPL during Drosophila development.

Kim HJ, Kim SH, Shim SO, Park E, Kim C, Kim K, Tanouye MA, Yim J.

Cell Death Differ. 2007 Jan;14(1):103-15. Epub 2006 Apr 21.

19.

Making an escape: development and function of the Drosophila giant fibre system.

Allen MJ, Godenschwege TA, Tanouye MA, Phelan P.

Semin Cell Dev Biol. 2006 Feb;17(1):31-41. Epub 2005 Dec 27. Review.

PMID:
16378740
20.

Seizure suppression by shakB2, a gap junction mutation in Drosophila.

Song J, Tanouye MA.

J Neurophysiol. 2006 Feb;95(2):627-35. Epub 2005 Sep 28.

21.

The mei-P26 gene encodes a RING finger B-box coiled-coil-NHL protein that regulates seizure susceptibility in Drosophilia.

Glasscock E, Singhania A, Tanouye MA.

Genetics. 2005 Aug;170(4):1677-89. Epub 2005 Jun 3.

22.

Drosophila couch potato mutants exhibit complex neurological abnormalities including epilepsy phenotypes.

Glasscock E, Tanouye MA.

Genetics. 2005 Apr;169(4):2137-49. Epub 2005 Jan 31.

23.

Seizure suppression by gain-of-function escargot mutations.

Hekmat-Scafe DS, Dang KN, Tanouye MA.

Genetics. 2005 Mar;169(3):1477-93. Epub 2005 Jan 16.

24.
25.

Genome-wide analysis of the odorant-binding protein gene family in Drosophila melanogaster.

Hekmat-Scafe DS, Scafe CR, McKinney AJ, Tanouye MA.

Genome Res. 2002 Sep;12(9):1357-69.

26.

Genetic suppression of seizure susceptibility in Drosophila.

Kuebler D, Zhang H, Ren X, Tanouye MA.

J Neurophysiol. 2001 Sep;86(3):1211-25.

27.

Modifications of seizure susceptibility in Drosophila.

Kuebler D, Tanouye MA.

J Neurophysiol. 2000 Feb;83(2):998-1009.

28.

Interspecific movement of the paternal sex ratio chromosome.

Dobson SL, Tanouye MA.

Heredity (Edinb). 1998 Sep;81 ( Pt 3):261-9.

30.

Identification of a Drosophila muscle development gene with structural homology to mammalian early growth response transcription factors.

Lee JC, VijayRaghavan K, Celniker SE, Tanouye MA.

Proc Natl Acad Sci U S A. 1995 Oct 24;92(22):10344-8.

31.
32.
33.

bendless, a Drosophila gene affecting neuronal connectivity, encodes a ubiquitin-conjugating enzyme homolog.

Oh CE, McMahon R, Benzer S, Tanouye MA.

J Neurosci. 1994 May;14(5 Pt 2):3166-79.

34.

Tandem linkage of Shaker K+ channel subunits does not ensure the stoichiometry of expressed channels.

McCormack K, Lin L, Iverson LE, Tanouye MA, Sigworth FJ.

Biophys J. 1992 Nov;63(5):1406-11.

35.

The size of gating charge in wild-type and mutant Shaker potassium channels.

Schoppa NE, McCormack K, Tanouye MA, Sigworth FJ.

Science. 1992 Mar 27;255(5052):1712-5.

PMID:
1553560
36.

A role for hydrophobic residues in the voltage-dependent gating of Shaker K+ channels.

McCormack K, Tanouye MA, Iverson LE, Lin JW, Ramaswami M, McCormack T, Campanelli JT, Mathew MK, Rudy B.

Proc Natl Acad Sci U S A. 1991 Apr 1;88(7):2931-5.

37.

Expression of ion channel genes in Drosophila.

Tseng-Crank J, Pollock JA, Hayashi I, Tanouye MA.

J Neurogenet. 1991;7(4):229-39.

PMID:
1653317
38.

Human potassium channel genes: Molecular cloning and functional expression.

Ramaswami M, Gautam M, Kamb A, Rudy B, Tanouye MA, Mathew MK.

Mol Cell Neurosci. 1990 Dec;1(3):214-23.

PMID:
19912772
39.

Molecular cloning and functional expression of a potassium channel cDNA isolated from a rat cardiac library.

Tseng-Crank JC, Tseng GN, Schwartz A, Tanouye MA.

FEBS Lett. 1990 Jul 30;268(1):63-8.

40.
41.

Genetic analysis of the Shaker gene complex of Drosophila melanogaster.

Ferrús A, Llamazares S, de la Pompa JL, Tanouye MA, Pongs O.

Genetics. 1990 Jun;125(2):383-98.

42.

Expression of Drosophila Shaker potassium channels in mammalian cells infected with recombinant vaccinia virus.

Leonard RJ, Karschin A, Jayashree-Aiyar S, Davidson N, Tanouye MA, Thomas L, Thomas G, Lester HA.

Proc Natl Acad Sci U S A. 1989 Oct;86(19):7629-33.

43.

Two sodium-channel genes in Drosophila: implications for channel diversity.

Ramaswami M, Tanouye MA.

Proc Natl Acad Sci U S A. 1989 Mar;86(6):2079-82.

44.

A-type potassium channels expressed from Shaker locus cDNA.

Iverson LE, Tanouye MA, Lester HA, Davidson N, Rudy B.

Proc Natl Acad Sci U S A. 1988 Aug;85(15):5723-7.

45.

Multiple products of the Drosophila Shaker gene may contribute to potassium channel diversity.

Kamb A, Tseng-Crank J, Tanouye MA.

Neuron. 1988 Jul;1(5):421-30.

PMID:
3272175
46.

Molecular characterization of Shaker, a Drosophila gene that encodes a potassium channel.

Kamb A, Iverson LE, Tanouye MA.

Cell. 1987 Jul 31;50(3):405-13.

PMID:
2440582
47.

Genetics of ion channels.

Salkoff LB, Tanouye MA.

Physiol Rev. 1986 Apr;66(2):301-29. Review. No abstract available.

PMID:
2421364
48.

Genetics and molecular biology of ionic channels in Drosophila.

Tanouye MA, Kamb CA, Iverson LE, Salkoff L.

Annu Rev Neurosci. 1986;9:255-76. Review. No abstract available.

PMID:
2423005
49.

Action potentials in normal and Shaker mutant Drosophila.

Tanouye MA, Ferrus A.

J Neurogenet. 1985 Sep;2(4):253-71.

PMID:
3936906
50.

Abnormal action potentials associated with the Shaker complex locus of Drosophila.

Tanouye MA, Ferrus A, Fujita SC.

Proc Natl Acad Sci U S A. 1981 Oct;78(10):6548-52.

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