Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 138


Frequent Homozygous Deletions of Type I Interferon Genes in Pleural Mesothelioma Confer Sensitivity to Oncolytic Measles Virus.

Delaunay T, Achard C, Boisgerault N, Grard M, Petithomme T, Chatelain C, Dutoit S, Blanquart C, Royer PJ, Minvielle S, Quetel L, Meiller C, Jean D, Fradin D, Bennouna J, Magnan A, Cellerin L, Tangy F, Grégoire M, Fonteneau JF.

J Thorac Oncol. 2020 Jan 13. pii: S1556-0864(20)30019-8. doi: 10.1016/j.jtho.2019.12.128. [Epub ahead of print]


E3 Ligase ITCH Interacts with the Z Matrix Protein of Lassa and Mopeia Viruses and Is Required for the Release of Infectious Particles.

Baillet N, Krieger S, Carnec X, Mateo M, Journeaux A, Merabet O, Caro V, Tangy F, Vidalain PO, Baize S.

Viruses. 2019 Dec 31;12(1). pii: E49. doi: 10.3390/v12010049.


Chemical composition, Fatty acids profile and Biological properties of Thymus capitatus (L.) Hoffmanns, essential Oil.

Zaïri A, Nouir S, Zarrouk A, Haddad H, Khélifa A, Achour L, Tangy F, Chaouachi M, Trabelsi M.

Sci Rep. 2019 Dec 27;9(1):20134. doi: 10.1038/s41598-019-56580-y.


An RNA-Binding Protein Secreted by a Bacterial Pathogen Modulates RIG-I Signaling.

Pagliuso A, Tham TN, Allemand E, Robertin S, Dupuy B, Bertrand Q, Bécavin C, Koutero M, Najburg V, Nahori MA, Tangy F, Stavru F, Bessonov S, Dessen A, Muchardt C, Lebreton A, Komarova AV, Cossart P.

Cell Host Microbe. 2019 Dec 11;26(6):823-835.e11. doi: 10.1016/j.chom.2019.10.004. Epub 2019 Nov 21.


Vaccines inducing immunity to Lassa virus glycoprotein and nucleoprotein protect macaques after a single shot.

Mateo M, Reynard S, Carnec X, Journeaux A, Baillet N, Schaeffer J, Picard C, Legras-Lachuer C, Allan R, Perthame E, Hillion KH, Pietrosemoli N, Dillies MA, Barrot L, Vallve A, Barron S, Fellmann L, Gaillard JC, Armengaud J, Carbonnelle C, Raoul H, Tangy F, Baize S.

Sci Transl Med. 2019 Oct 2;11(512). pii: eaaw3163. doi: 10.1126/scitranslmed.aaw3163.


LGP2 binds to PACT to regulate RIG-I- and MDA5-mediated antiviral responses.

Sanchez David RY, Combredet C, Najburg V, Millot GA, Beauclair G, Schwikowski B, Léger T, Camadro JM, Jacob Y, Bellalou J, Jouvenet N, Tangy F, Komarova AV.

Sci Signal. 2019 Oct 1;12(601). pii: eaar3993. doi: 10.1126/scisignal.aar3993.


A Functional Assay to Determine the Capacity of Oncolytic Viruses to Induce Immunogenic Tumor Cell Death.

Delaunay T, Achard C, Grégoire M, Tangy F, Boisgerault N, Fonteneau JF.

Methods Mol Biol. 2020;2058:127-132. doi: 10.1007/978-1-4939-9794-7_8.


Midgut barriers prevent the replication and dissemination of the yellow fever vaccine in Aedes aegypti.

Danet L, Beauclair G, Berthet M, Moratorio G, Gracias S, Tangy F, Choumet V, Jouvenet N.

PLoS Negl Trop Dis. 2019 Aug 14;13(8):e0007299. doi: 10.1371/journal.pntd.0007299. eCollection 2019 Aug.


Autophagy Promotes Infectious Particle Production of Mopeia and Lassa Viruses.

Baillet N, Krieger S, Journeaux A, Caro V, Tangy F, Vidalain PO, Baize S.

Viruses. 2019 Mar 23;11(3). pii: E293. doi: 10.3390/v11030293.


Recombinant measles vaccine expressing malaria antigens induces long-term memory and protection in mice.

Mura M, Ruffié C, Combredet C, Aliprandini E, Formaglio P, Chitnis CE, Amino R, Tangy F.

NPJ Vaccines. 2019 Feb 27;4:12. doi: 10.1038/s41541-019-0106-8. eCollection 2019.


Evaluation of the Antiviral Activity of Sephin1 Treatment and Its Consequences on eIF2α Phosphorylation in Response to Viral Infections.

Fusade-Boyer M, Dupré G, Bessière P, Khiar S, Quentin-Froignant C, Beck C, Lecollinet S, Rameix-Welti MA, Eléouët JF, Tangy F, Lajoie B, Bertagnoli S, Vidalain PO, Gallardo F, Volmer R.

Front Immunol. 2019 Feb 12;10:134. doi: 10.3389/fimmu.2019.00134. eCollection 2019.


Strong antigen-specific T-cell immunity induced by a recombinant human TERT measles virus vaccine and amplified by a DNA/viral vector prime boost in IFNAR/CD46 mice.

Pliquet E, Ruffie C, Escande M, Thalmensi J, Najburg V, Combredet C, Bestetti T, Julithe M, Liard C, Huet T, Wain-Hobson S, Tangy F, Langlade-Demoyen P.

Cancer Immunol Immunother. 2019 Apr;68(4):533-544. doi: 10.1007/s00262-018-2272-3. Epub 2019 Jan 17.


Uncovering Flavivirus Host Dependency Factors through a Genome-Wide Gain-of-Function Screen.

Petrova E, Gracias S, Beauclair G, Tangy F, Jouvenet N.

Viruses. 2019 Jan 15;11(1). pii: E68. doi: 10.3390/v11010068.


Measles-vectored vaccine approaches against viral infections: a focus on Chikungunya.

Gerke C, Frantz PN, Ramsauer K, Tangy F.

Expert Rev Vaccines. 2019 Apr;18(4):393-403. doi: 10.1080/14760584.2019.1562908. Epub 2019 Mar 11.


p53 regulates CD46 expression and measles virus infection in myeloma cells.

Lok A, Descamps G, Tessoulin B, Chiron D, Eveillard M, Godon C, Le Bris Y, Vabret A, Bellanger C, Maillet L, Barillé-Nion S, Gregoire M, Fonteneau JF, Le Gouill S, Moreau P, Tangy F, Amiot M, Moreau-Aubry A, Pellat-Deceunynck C.

Blood Adv. 2018 Dec 11;2(23):3492-3505. doi: 10.1182/bloodadvances.2018025106.


hCD46 receptor is not required for measles vaccine Schwarz strain replication in vivo: Type-I IFN is the species barrier in mice.

Mura M, Ruffié C, Billon-Denis E, Combredet C, Tournier JN, Tangy F.

Virology. 2018 Nov;524:151-159. doi: 10.1016/j.virol.2018.08.014. Epub 2018 Sep 7.


Bringing vaccinology to the world.

Gerke C, Phalipon A, Tangy F.

Hum Vaccin Immunother. 2018;14(9):2105-2106. doi: 10.1080/21645515.2018.1490379. Epub 2018 Jul 26. No abstract available.


Immature particles and capsid-free viral RNA produced by Yellow fever virus-infected cells stimulate plasmacytoid dendritic cells to secrete interferons.

Sinigaglia L, Gracias S, Décembre E, Fritz M, Bruni D, Smith N, Herbeuval JP, Martin A, Dreux M, Tangy F, Jouvenet N.

Sci Rep. 2018 Jul 18;8(1):10889. doi: 10.1038/s41598-018-29235-7.


DI-tector: defective interfering viral genomes' detector for next-generation sequencing data.

Beauclair G, Mura M, Combredet C, Tangy F, Jouvenet N, Komarova AV.

RNA. 2018 Oct;24(10):1285-1296. doi: 10.1261/rna.066910.118. Epub 2018 Jul 16.


RIG-I Recognizes the 5' Region of Dengue and Zika Virus Genomes.

Chazal M, Beauclair G, Gracias S, Najburg V, Simon-Lorière E, Tangy F, Komarova AV, Jouvenet N.

Cell Rep. 2018 Jul 10;24(2):320-328. doi: 10.1016/j.celrep.2018.06.047.


Measles-derived vaccines to prevent emerging viral diseases.

Frantz PN, Teeravechyan S, Tangy F.

Microbes Infect. 2018 Oct - Nov;20(9-10):493-500. doi: 10.1016/j.micinf.2018.01.005. Epub 2018 Feb 1. Review.


Oncolytic viruses sensitize human tumor cells for NY-ESO-1 tumor antigen recognition by CD4+ effector T cells.

Delaunay T, Violland M, Boisgerault N, Dutoit S, Vignard V, Münz C, Gannage M, Dréno B, Vaivode K, Pjanova D, Labarrière N, Wang Y, Chiocca EA, Boeuf FL, Bell JC, Erbs P, Tangy F, Grégoire M, Fonteneau JF.

Oncoimmunology. 2017 Dec 26;7(3):e1407897. doi: 10.1080/2162402X.2017.1407897. eCollection 2018.


Original Chemical Series of Pyrimidine Biosynthesis Inhibitors That Boost the Antiviral Interferon Response.

Lucas-Hourani M, Dauzonne D, Munier-Lehmann H, Khiar S, Nisole S, Dairou J, Helynck O, Afonso PV, Tangy F, Vidalain PO.

Antimicrob Agents Chemother. 2017 Sep 22;61(10). pii: e00383-17. doi: 10.1128/AAC.00383-17. Print 2017 Oct.


Nonencapsidated 5' Copy-Back Defective Interfering Genomes Produced by Recombinant Measles Viruses Are Recognized by RIG-I and LGP2 but Not MDA5.

Mura M, Combredet C, Najburg V, Sanchez David RY, Tangy F, Komarova AV.

J Virol. 2017 Sep 27;91(20). pii: e00643-17. doi: 10.1128/JVI.00643-17. Print 2017 Oct 15.


Yeast lysates carrying the nucleoprotein from measles virus vaccine as a novel subunit vaccine platform to deliver Plasmodium circumsporozoite antigen.

Jacob D, Ruffie C, Combredet C, Formaglio P, Amino R, Ménard R, Tangy F, Sala M.

Malar J. 2017 Jun 29;16(1):259. doi: 10.1186/s12936-017-1908-7.


Identification of a small molecule that primes the type I interferon response to cytosolic DNA.

Khiar S, Lucas-Hourani M, Nisole S, Smith N, Helynck O, Bourgine M, Ruffié C, Herbeuval JP, Munier-Lehmann H, Tangy F, Vidalain PO.

Sci Rep. 2017 May 31;7(1):2561. doi: 10.1038/s41598-017-02776-z.


HSV-1/HSV-2 Infection-Related Cancers in Bantu Populations Driving HIV-1 Prevalence in Africa: Tracking the Origin of AIDS at the Onset of the 20th Century.

Le Goaster J, Bouree P, El Sissy FN, Phuong Bui F, Pokossy Epee J, Rollin P, Tangy F, Haenni AL.

Case Rep Oncol. 2016 Nov 29;9(3):815-825. doi: 10.1159/000450939. eCollection 2016 Sep-Dec.


Oncolytic measles virus induces tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated cytotoxicity by human myeloid and plasmacytoid dendritic cells.

Achard C, Guillerme JB, Bruni D, Boisgerault N, Combredet C, Tangy F, Jouvenet N, Grégoire M, Fonteneau JF.

Oncoimmunology. 2016 Nov 18;6(1):e1261240. doi: 10.1080/2162402X.2016.1261240. eCollection 2017.


Modulation of the Type I Interferon Response Defines the Sensitivity of Human Melanoma Cells to Oncolytic Measles Virus.

Allagui F, Achard C, Panterne C, Combredet C, Labarrière N, Dréno B, Elgaaied AB, Pouliquen D, Tangy F, Fonteneau JF, Grégoire M, Boisgerault N.

Curr Gene Ther. 2017;16(6):419-428. doi: 10.2174/1566523217666170102110502.


Chikungunya Virus Vaccines: Viral Vector-Based Approaches.

Ramsauer K, Tangy F.

J Infect Dis. 2016 Dec 15;214(suppl 5):S500-S505.


The CREB3-Herp signalling module limits the cytosolic calcium concentration increase and apoptosis induced by poliovirus.

Mirabelli C, Pelletier I, Téoulé F, Vidalain PO, Brisac C, Tangy F, Delpeyroux F, Blondel B.

J Gen Virol. 2016 Sep;97(9):2194-2200. doi: 10.1099/jgv.0.000544. Epub 2016 Jul 12.


HIV-Infected Dendritic Cells Present Endogenous MHC Class II-Restricted Antigens to HIV-Specific CD4+ T Cells.

Coulon PG, Richetta C, Rouers A, Blanchet FP, Urrutia A, Guerbois M, Piguet V, Theodorou I, Bet A, Schwartz O, Tangy F, Graff-Dubois S, Cardinaud S, Moris A.

J Immunol. 2016 Jul 15;197(2):517-32. doi: 10.4049/jimmunol.1600286. Epub 2016 Jun 10.


Comparative analysis of viral RNA signatures on different RIG-I-like receptors.

Sanchez David RY, Combredet C, Sismeiro O, Dillies MA, Jagla B, Coppée JY, Mura M, Guerbois Galla M, Despres P, Tangy F, Komarova AV.

Elife. 2016 Mar 24;5:e11275. doi: 10.7554/eLife.11275.


Biosafety considerations for attenuated measles virus vectors used in virotherapy and vaccination.

Baldo A, Galanis E, Tangy F, Herman P.

Hum Vaccin Immunother. 2016 May 3;12(5):1102-16. doi: 10.1080/21645515.2015.1122146. Epub 2015 Dec 2. Review.


Respiratory syncytial virus infection in macaques is not suppressed by intranasal sprays of pyrimidine biosynthesis inhibitors.

Grandin C, Hourani ML, Janin YL, Dauzonne D, Munier-Lehmann H, Paturet A, Taborik F, Vabret A, Contamin H, Tangy F, Vidalain PO.

Antiviral Res. 2016 Jan;125:58-62. doi: 10.1016/j.antiviral.2015.11.006. Epub 2015 Nov 22.


Sensitivity of human pleural mesothelioma to oncolytic measles virus depends on defects of the type I interferon response.

Achard C, Boisgerault N, Delaunay T, Roulois D, Nedellec S, Royer PJ, Pain M, Combredet C, Mesel-Lemoine M, Cellerin L, Magnan A, Tangy F, Grégoire M, Fonteneau JF.

Oncotarget. 2015 Dec 29;6(42):44892-904. doi: 10.18632/oncotarget.6285.


Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH).

Lucas-Hourani M, Munier-Lehmann H, El Mazouni F, Malmquist NA, Harpon J, Coutant EP, Guillou S, Helynck O, Noel A, Scherf A, Phillips MA, Tangy F, Vidalain PO, Janin YL.

J Med Chem. 2015 Jul 23;58(14):5579-98. doi: 10.1021/acs.jmedchem.5b00606. Epub 2015 Jun 30.


Herpes Viral Origin of the Parsonage-Turner Syndrome: Highlighting of Serological Immune Anti-Herpes Deficiency Cured by Anti-Herpes Therapy.

Goaster JL, Bourée P, Ifergan C, Tangy F, Olivier R, Haenni AL.

Case Rep Neurol. 2015 May 13;7(2):110-4. doi: 10.1159/000381945. eCollection 2015 May-Aug.


Immunogenicity, safety, and tolerability of a recombinant measles-virus-based chikungunya vaccine: a randomised, double-blind, placebo-controlled, active-comparator, first-in-man trial.

Ramsauer K, Schwameis M, Firbas C, Müllner M, Putnak RJ, Thomas SJ, Desprès P, Tauber E, Jilma B, Tangy F.

Lancet Infect Dis. 2015 May;15(5):519-27. doi: 10.1016/S1473-3099(15)70043-5. Epub 2015 Mar 2.


A field-proven yeast two-hybrid protocol used to identify coronavirus-host protein-protein interactions.

Vidalain PO, Jacob Y, Hagemeijer MC, Jones LM, Neveu G, Roussarie JP, Rottier PJ, Tangy F, de Haan CA.

Methods Mol Biol. 2015;1282:213-29. doi: 10.1007/978-1-4939-2438-7_18.


[Stimulation of the antiviral innate immune response by pyrimidine biosynthesis inhibitors: a surprise of phenotypic screening].

Vidalain PO, Lucas-Hourani M, Helynck O, Tangy F, Munier-Lehmann H.

Med Sci (Paris). 2015 Jan;31(1):98-104. doi: 10.1051/medsci/20153101019. Epub 2015 Feb 6. Review. French.


Original 2-(3-alkoxy-1H-pyrazol-1-yl)pyrimidine derivatives as inhibitors of human dihydroorotate dehydrogenase (DHODH).

Munier-Lehmann H, Lucas-Hourani M, Guillou S, Helynck O, Zanghi G, Noel A, Tangy F, Vidalain PO, Janin YL.

J Med Chem. 2015 Jan 22;58(2):860-77. doi: 10.1021/jm501446r. Epub 2015 Jan 6.


Oncolytic virotherapy for human malignant mesothelioma: recent advances.

Boisgerault N, Achard C, Delaunay T, Cellerin L, Tangy F, Grégoire M, Fonteneau JF.

Oncolytic Virother. 2015 Sep 10;4:133-40. doi: 10.2147/OV.S66091. eCollection 2015. Review.


Evidence for an intranasal immune response to human respiratory syncytial virus infection in cynomolgus macaques.

Grandin C, Lucas-Hourani M, Clavel M, Taborik F, Vabret A, Tangy F, Contamin H, Vidalain PO.

J Gen Virol. 2015 Apr;96(Pt 4):782-92. doi: 10.1099/vir.0.000039. Epub 2014 Dec 23.


Use of SLAM and PVRL4 and identification of pro-HB-EGF as cell entry receptors for wild type phocine distemper virus.

Melia MM, Earle JP, Abdullah H, Reaney K, Tangy F, Cosby SL.

PLoS One. 2014 Aug 29;9(8):e106281. doi: 10.1371/journal.pone.0106281. eCollection 2014.


High-throughput screening for broad-spectrum chemical inhibitors of RNA viruses.

Lucas-Hourani M, Munier-Lehmann H, Helynck O, Komarova A, Desprès P, Tangy F, Vidalain PO.

J Vis Exp. 2014 May 5;(87). doi: 10.3791/51222.


Protection from SARS coronavirus conferred by live measles vaccine expressing the spike glycoprotein.

Escriou N, Callendret B, Lorin V, Combredet C, Marianneau P, Février M, Tangy F.

Virology. 2014 Mar;452-453:32-41. doi: 10.1016/j.virol.2014.01.002. Epub 2014 Jan 28.


In vitro activities of dermaseptins K4S4 and K4K20S4 against Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa planktonic growth and biofilm formation.

Zaïri A, Ferrières L, Latour-Lambert P, Beloin C, Tangy F, Ghigo JM, Hani K.

Antimicrob Agents Chemother. 2014;58(4):2221-8. doi: 10.1128/AAC.02142-13. Epub 2014 Feb 3.


Large-scale nucleotide optimization of simian immunodeficiency virus reduces its capacity to stimulate type I interferon in vitro.

Vabret N, Bailly-Bechet M, Lepelley A, Najburg V, Schwartz O, Verrier B, Tangy F.

J Virol. 2014 Apr;88(8):4161-72. doi: 10.1128/JVI.03223-13. Epub 2014 Jan 29.


Whole Pichia pastoris yeast expressing measles virus nucleoprotein as a production and delivery system to multimerize Plasmodium antigens.

Jacob D, Ruffie C, Dubois M, Combredet C, Amino R, Formaglio P, Gorgette O, Pehau-Arnaudet G, Guery C, Puijalon O, Barale JC, Ménard R, Tangy F, Sala M.

PLoS One. 2014 Jan 27;9(1):e86658. doi: 10.1371/journal.pone.0086658. eCollection 2014.

Supplemental Content

Support Center