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Items: 1 to 50 of 199


Assessing the hazard of E-Cigarette flavor mixtures using zebrafish.

Holden LL, Truong L, Simonich MT, Tanguay RL.

Food Chem Toxicol. 2019 Nov 8:110945. doi: 10.1016/j.fct.2019.110945. [Epub ahead of print]


Otoferlin Depletion Results in Abnormal Synaptic Ribbons and Altered Intracellular Calcium Levels in Zebrafish.

Manchanda A, Chatterjee P, Bonventre JA, Haggard DE, Kindt KS, Tanguay RL, Johnson CP.

Sci Rep. 2019 Oct 3;9(1):14273. doi: 10.1038/s41598-019-50710-2.


Treatment with Nitrate, but Not Nitrite, Lowers the Oxygen Cost of Exercise and Decreases Glycolytic Intermediates While Increasing Fatty Acid Metabolites in Exercised Zebrafish.

Axton ER, Beaver LM, St Mary L, Truong L, Logan CR, Spagnoli S, Prater MC, Keller RM, Garcia-Jaramillo M, Ehrlicher SE, Stierwalt HD, Newsom SA, Robinson MM, Tanguay RL, Stevens JF, Hord NG.

J Nutr. 2019 Dec 1;149(12):2120-2132. doi: 10.1093/jn/nxz202.


Time-dependent behavioral data from zebrafish reveals novel signatures of chemical toxicity using point of departure analysis.

Thomas DG, Shankaran H, Truong L, Tanguay RL, Waters KM.

Comput Toxicol. 2019 Feb;9:50-60. doi: 10.1016/j.comtox.2018.11.001. Epub 2018 Nov 10.


Tris(1,3-dichloro-2-propyl)phosphate (TDCIPP) disrupts zebrafish tail fin development.

Rhyu D, Lee H, Tanguay RL, Kim KT.

Ecotoxicol Environ Saf. 2019 Oct 30;182:109449. doi: 10.1016/j.ecoenv.2019.109449. Epub 2019 Jul 27.


Glucocorticoid receptor-dependent induction of cripto-1 (one-eyed pinhead) inhibits zebrafish caudal fin regeneration.

Garland MA, Sengupta S, Mathew LK, Truong L, de Jong E, Piersma AH, La Du J, Tanguay RL.

Toxicol Rep. 2019 May 29;6:529-537. doi: 10.1016/j.toxrep.2019.05.013. eCollection 2019.


Neurodevelopmental toxicity assessments of alkyl phenanthrene and Dechlorane Plus co-exposure in zebrafish.

Chen X, Chen Y, Huang C, Dong Q, Roper C, Tanguay RL, Zhu Y, Zhang Y.

Ecotoxicol Environ Saf. 2019 Sep 30;180:762-769. doi: 10.1016/j.ecoenv.2019.05.066. Epub 2019 May 30.


Coupling Genome-wide Transcriptomics and Developmental Toxicity Profiles in Zebrafish to Characterize Polycyclic Aromatic Hydrocarbon (PAH) Hazard.

Shankar P, Geier MC, Truong L, McClure RS, Pande P, Waters KM, Tanguay RL.

Int J Mol Sci. 2019 May 25;20(10). pii: E2570. doi: 10.3390/ijms20102570.


Bioinformatics Resource Manager: a systems biology web tool for microRNA and omics data integration.

Brown J, Phillips AR, Lewis DA, Mans MA, Chang Y, Tanguay RL, Peterson ES, Waters KM, Tilton SC.

BMC Bioinformatics. 2019 May 17;20(1):255. doi: 10.1186/s12859-019-2805-6.


Determination of narcotic potency using a neurobehavioral assay with larval zebrafish.

Broening HW, La Du J, Carr GJ, Nash JF, Truong L, Tanguay RL.

Neurotoxicology. 2019 Sep;74:67-73. doi: 10.1016/j.neuro.2019.05.005. Epub 2019 May 11.


Formation of PAH Derivatives and Increased Developmental Toxicity during Steam Enhanced Extraction Remediation of Creosote Contaminated Superfund Soil.

Trine LSD, Davis EL, Roper C, Truong L, Tanguay RL, Simonich SLM.

Environ Sci Technol. 2019 Apr 16;53(8):4460-4469. doi: 10.1021/acs.est.8b07231. Epub 2019 Apr 8.


Systematic determination of the relationship between nanoparticle core diameter and toxicity for a series of structurally analogous gold nanoparticles in zebrafish.

Truong L, Zaikova T, Baldock BL, Balik-Meisner M, To K, Reif DM, Kennedy ZC, Hutchison JE, Tanguay RL.

Nanotoxicology. 2019 Sep;13(7):879-893. doi: 10.1080/17435390.2019.1592259. Epub 2019 Apr 2.


Improved in vivo targeting of BCL-2 phenotypic conversion through hollow gold nanoshell delivery.

Morgan E, Gamble JT, Pearce MC, Elson DJ, Tanguay RL, Kolluri SK, Reich NO.

Apoptosis. 2019 Jun;24(5-6):529-537. doi: 10.1007/s10495-019-01531-1.


Copper release and transformation following natural weathering of nano-enabled pressure-treated lumber.

Lankone RS, Challis K, Pourzahedi L, Durkin DP, Bi Y, Wang Y, Garland MA, Brown F, Hristovski K, Tanguay RL, Westerhoff P, Lowry G, Gilbertson LM, Ranville J, Fairbrother DH.

Sci Total Environ. 2019 Jun 10;668:234-244. doi: 10.1016/j.scitotenv.2019.01.433. Epub 2019 Feb 27.


PM2.5 Filter Extraction Methods: Implications for Chemical and Toxicological Analyses.

Roper C, Delgado LS, Barrett D, Massey Simonich SL, Tanguay RL.

Environ Sci Technol. 2019 Jan 2;53(1):434-442. doi: 10.1021/acs.est.8b04308. Epub 2018 Dec 12.


Characterizing sources of variability in zebrafish embryo screening protocols.

Hamm JT, Ceger P, Allen D, Stout M, Maull EA, Baker G, Zmarowski A, Padilla S, Perkins E, Planchart A, Stedman D, Tal T, Tanguay RL, Volz DC, Wilbanks MS, Walker NJ.

ALTEX. 2019;36(1):103-120. doi: 10.14573/altex.1804162. Epub 2018 Nov 10.


Signaling Events Downstream of AHR Activation That Contribute to Toxic Responses: The Functional Role of an AHR-Dependent Long Noncoding RNA (slincR) Using the Zebrafish Model.

Garcia GR, Shankar P, Dunham CL, Garcia A, La Du JK, Truong L, Tilton SC, Tanguay RL.

Environ Health Perspect. 2018 Nov;126(11):117002. doi: 10.1289/EHP3281.


Biodegradability and toxicity of monorhamnolipid biosurfactant diastereomers.

Hogan DE, Tian F, Malm SW, Olivares C, Palos Pacheco R, Simonich MT, Hunjan AS, Tanguay RL, Klimecki WT, Polt R, Pemberton JE, Curry JE, Maier RM.

J Hazard Mater. 2019 Feb 15;364:600-607. doi: 10.1016/j.jhazmat.2018.10.050. Epub 2018 Nov 1.


Elucidating Gene-by-Environment Interactions Associated with Differential Susceptibility to Chemical Exposure.

Balik-Meisner M, Truong L, Scholl EH, La Du JK, Tanguay RL, Reif DM.

Environ Health Perspect. 2018 Jun 28;126(6):067010. doi: 10.1289/EHP2662. eCollection 2018 Jun.


Induction of apoptosis and suppression of tumor growth by Nur77-derived Bcl-2 converting peptide in chemoresistant lung cancer cells.

Pearce MC, Gamble JT, Kopparapu PR, O'Donnell EF, Mueller MJ, Jang HS, Greenwood JA, Satterthwait AC, Tanguay RL, Zhang XK, Kolluri SK.

Oncotarget. 2018 May 25;9(40):26072-26085. doi: 10.18632/oncotarget.25437. eCollection 2018 May 25.


Development of a high-throughput in vivo screening platform for particulate matter exposures.

Roper C, Simonich SLM, Tanguay RL.

Environ Pollut. 2018 Apr;235:993-1005. doi: 10.1016/j.envpol.2018.01.025. Epub 2018 Feb 21.


The Rise of Zebrafish as a Model for Toxicology.

Tanguay RL.

Toxicol Sci. 2018 May 1;163(1):3-4. doi: 10.1093/toxsci/kfx295. No abstract available.


Synergistic Toxicity Produced by Mixtures of Biocompatible Gold Nanoparticles and Widely Used Surfactants.

Ginzburg AL, Truong L, Tanguay RL, Hutchison JE.

ACS Nano. 2018 Jun 26;12(6):5312-5322. doi: 10.1021/acsnano.8b00036. Epub 2018 May 16.


Trade-offs in ecosystem impacts from nanomaterial versus organic chemical ultraviolet filters in sunscreens.

Hanigan D, Truong L, Schoepf J, Nosaka T, Mulchandani A, Tanguay RL, Westerhoff P.

Water Res. 2018 Aug 1;139:281-290. doi: 10.1016/j.watres.2018.03.062. Epub 2018 Mar 27.


Systematic developmental neurotoxicity assessment of a representative PAH Superfund mixture using zebrafish.

Geier MC, James Minick D, Truong L, Tilton S, Pande P, Anderson KA, Teeguardan J, Tanguay RL.

Toxicol Appl Pharmacol. 2018 Sep 1;354:115-125. doi: 10.1016/j.taap.2018.03.029. Epub 2018 Apr 6.


Multidimensional chemobehavior analysis of flavonoids and neuroactive compounds in zebrafish.

Bugel SM, Tanguay RL.

Toxicol Appl Pharmacol. 2018 Apr 1;344:23-34. doi: 10.1016/j.taap.2018.02.019. Epub 2018 Feb 27.


AHR2 required for normal behavioral responses and proper development of the skeletal and reproductive systems in zebrafish.

Garcia GR, Bugel SM, Truong L, Spagnoli S, Tanguay RL.

PLoS One. 2018 Mar 1;13(3):e0193484. doi: 10.1371/journal.pone.0193484. eCollection 2018.


Transcriptomic and phenotypic profiling in developing zebrafish exposed to thyroid hormone receptor agonists.

Haggard DE, Noyes PD, Waters KM, Tanguay RL.

Reprod Toxicol. 2018 Apr;77:80-93. doi: 10.1016/j.reprotox.2018.02.006. Epub 2018 Feb 16.


Population genetic diversity in zebrafish lines.

Balik-Meisner M, Truong L, Scholl EH, Tanguay RL, Reif DM.

Mamm Genome. 2018 Feb;29(1-2):90-100. doi: 10.1007/s00335-018-9735-x. Epub 2018 Jan 24.


Developmental and behavioral alterations in zebrafish embryonically exposed to valproic acid (VPA): An aquatic model for autism.

Chen J, Lei L, Tian L, Hou F, Roper C, Ge X, Zhao Y, Chen Y, Dong Q, Tanguay RL, Huang C.

Neurotoxicol Teratol. 2018 Mar - Apr;66:8-16. doi: 10.1016/ Epub 2018 Jan 5.


Identification of a Raloxifene Analog That Promotes AhR-Mediated Apoptosis in Cancer Cells.

Jang HS, Pearce M, O'Donnell EF, Nguyen BD, Truong L, Mueller MJ, Bisson WH, Kerkvliet NI, Tanguay RL, Kolluri SK.

Biology (Basel). 2017 Dec 1;6(4). pii: E41. doi: 10.3390/biology6040041.


Comparative developmental toxicity of a comprehensive suite of polycyclic aromatic hydrocarbons.

Geier MC, Chlebowski AC, Truong L, Massey Simonich SL, Anderson KA, Tanguay RL.

Arch Toxicol. 2018 Feb;92(2):571-586. doi: 10.1007/s00204-017-2068-9. Epub 2017 Nov 1.


Ecotoxicity of the insensitive munitions compound 3-nitro-1,2,4-triazol-5-one (NTO) and its reduced metabolite 3-amino-1,2,4-triazol-5-one (ATO).

Madeira CL, Field JA, Simonich MT, Tanguay RL, Chorover J, Sierra-Alvarez R.

J Hazard Mater. 2018 Feb 5;343:340-346. doi: 10.1016/j.jhazmat.2017.09.052. Epub 2017 Sep 28.


Combinatorial effects of zinc deficiency and arsenic exposure on zebrafish (Danio rerio) development.

Beaver LM, Truong L, Barton CL, Chase TT, Gonnerman GD, Wong CP, Tanguay RL, Ho E.

PLoS One. 2017 Aug 24;12(8):e0183831. doi: 10.1371/journal.pone.0183831. eCollection 2017.


Investigating the application of a nitroreductase-expressing transgenic zebrafish line for high-throughput toxicity testing.

Chlebowski AC, La Du JK, Truong L, Massey Simonich SL, Tanguay RL.

Toxicol Rep. 2017;4:202-210. doi: 10.1016/j.toxrep.2017.04.005. Epub 2017 Apr 27.


Evaluation of Embryotoxicity Using the Zebrafish Model.

Truong L, Tanguay RL.

Methods Mol Biol. 2017;1641:325-333. doi: 10.1007/978-1-4939-7172-5_18.


Formation of Developmentally Toxic Phenanthrene Metabolite Mixtures by Mycobacterium sp. ELW1.

Schrlau JE, Kramer AL, Chlebowski A, Truong L, Tanguay RL, Simonich SLM, Semprini L.

Environ Sci Technol. 2017 Aug 1;51(15):8569-8578. doi: 10.1021/acs.est.7b01377. Epub 2017 Jul 20.


Colloidal Gold Nanoparticles Induce Changes in Cellular and Subcellular Morphology.

Ma X, Hartmann R, Jimenez de Aberasturi D, Yang F, Soenen SJH, Manshian BB, Franz J, Valdeperez D, Pelaz B, Feliu N, Hampp N, Riethmüller C, Vieker H, Frese N, Gölzhäuser A, Simonich M, Tanguay RL, Liang XJ, Parak WJ.

ACS Nano. 2017 Aug 22;11(8):7807-7820. doi: 10.1021/acsnano.7b01760. Epub 2017 Jul 18.


Transgenerational inheritance of neurobehavioral and physiological deficits from developmental exposure to benzo[a]pyrene in zebrafish.

Knecht AL, Truong L, Marvel SW, Reif DM, Garcia A, Lu C, Simonich MT, Teeguarden JG, Tanguay RL.

Toxicol Appl Pharmacol. 2017 Aug 15;329:148-157. doi: 10.1016/j.taap.2017.05.033. Epub 2017 Jun 3.



Noyes PD, Garcia GR, Tanguay RL.

Green Chem. 2016 Dec 21;18(24):6410-6430. doi: 10.1039/C6GC02061E. Epub 2016 Oct 21.


In Vivo Characterization of an AHR-Dependent Long Noncoding RNA Required for Proper Sox9b Expression.

Garcia GR, Goodale BC, Wiley MW, La Du JK, Hendrix DA, Tanguay RL.

Mol Pharmacol. 2017 Jun;91(6):609-619. doi: 10.1124/mol.117.108233. Epub 2017 Apr 6.


Alcohol use disorder and depression: proposed rewording of Choosing Wisely recommendation.

Tanguay RL, Lamba W, Fraser R, Mills P, Azarbar A, El-Guebaly N.

CMAJ. 2017 Mar 20;189(11):E442-E443. doi: 10.1503/cmaj.732873. No abstract available.


Using passive sampling and zebrafish to identify developmental toxicants in complex mixtures.

Bergmann AJ, Tanguay RL, Anderson KA.

Environ Toxicol Chem. 2017 Sep;36(9):2290-2298. doi: 10.1002/etc.3802. Epub 2017 Apr 17.


Adverse effects of parental zinc deficiency on metal homeostasis and embryonic development in a zebrafish model.

Beaver LM, Nkrumah-Elie YM, Truong L, Barton CL, Knecht AL, Gonnerman GD, Wong CP, Tanguay RL, Ho E.

J Nutr Biochem. 2017 May;43:78-87. doi: 10.1016/j.jnutbio.2017.02.006. Epub 2017 Feb 20.


Mechanistic Investigations Into the Developmental Toxicity of Nitrated and Heterocyclic PAHs.

Chlebowski AC, Garcia GR, La Du JK, Bisson WH, Truong L, Massey Simonich SL, Tanguay RL.

Toxicol Sci. 2017 May 1;157(1):246-259. doi: 10.1093/toxsci/kfx035.


A New Statistical Approach to Characterize Chemical-Elicited Behavioral Effects in High-Throughput Studies Using Zebrafish.

Zhang G, Truong L, Tanguay RL, Reif DM.

PLoS One. 2017 Jan 18;12(1):e0169408. doi: 10.1371/journal.pone.0169408. eCollection 2017.


Developmental benzo[a]pyrene (B[a]P) exposure impacts larval behavior and impairs adult learning in zebrafish.

Knecht AL, Truong L, Simonich MT, Tanguay RL.

Neurotoxicol Teratol. 2017 Jan - Feb;59:27-34. doi: 10.1016/ Epub 2016 Oct 27.


Comparative Toxicogenomic Responses to the Flame Retardant mITP in Developing Zebrafish.

Haggard DE, Das SR, Tanguay RL.

Chem Res Toxicol. 2017 Feb 20;30(2):508-515. doi: 10.1021/acs.chemrestox.6b00423. Epub 2016 Dec 13.


A data-driven weighting scheme for multivariate phenotypic endpoints recapitulates zebrafish developmental cascades.

Zhang G, Roell KR, Truong L, Tanguay RL, Reif DM.

Toxicol Appl Pharmacol. 2017 Jan 1;314:109-117. doi: 10.1016/j.taap.2016.11.010. Epub 2016 Nov 22.


Developmental bisphenol A exposure impairs sperm function and reproduction in zebrafish.

Chen J, Saili KS, Liu Y, Li L, Zhao Y, Jia Y, Bai C, Tanguay RL, Dong Q, Huang C.

Chemosphere. 2017 Feb;169:262-270. doi: 10.1016/j.chemosphere.2016.11.089. Epub 2016 Nov 20.


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