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Effect of basal insulin supplement therapy on diabetic retinopathy in short-duration type 2 diabetes: A one-year randomized parallel-group trial.

Mu PW, Tang XX, Tan Y, Wang YN, Lin S, Wang MM, Shu J, Wang J, Zhang YJ, Liang H, Lin BR, Cai MY, Chen YM.

J Diabetes. 2019 Apr 11. doi: 10.1111/1753-0407.12928. [Epub ahead of print]


Small-molecule ion channels increase host defences in cystic fibrosis airway epithelia.

Muraglia KA, Chorghade RS, Kim BR, Tang XX, Shah VS, Grillo AS, Daniels PN, Cioffi AG, Karp PH, Zhu L, Welsh MJ, Burke MD.

Nature. 2019 Mar;567(7748):405-408. doi: 10.1038/s41586-019-1018-5. Epub 2019 Mar 13.


Phenylephrine Attenuated Sepsis-Induced Cardiac Inflammation and Mitochondrial Injury Through an Effect on the PI3K/Akt Signaling Pathway.

Li HM, Li KY, Xing Y, Tang XX, Yang DM, Dai XM, Lu DX, Wang HD.

J Cardiovasc Pharmacol. 2019 Mar;73(3):186-194. doi: 10.1097/FJC.0000000000000651.


Fusarisolins A⁻E, Polyketides from the Marine-Derived Fungus Fusarium solani H918.

Niu S, Tang XX, Fan Z, Xia JM, Xie CL, Yang XW.

Mar Drugs. 2019 Feb 20;17(2). pii: E125. doi: 10.3390/md17020125.


New β-Lactone with Tea Pathogenic Fungus Inhibitory Effect from Marine-Derived Fungus MCCC3A00957.

Tang XX, Yan X, Fu WH, Yi LQ, Tang BW, Yu LB, Fang MJ, Wu Z, Qiu YK.

J Agric Food Chem. 2019 Mar 13;67(10):2877-2885. doi: 10.1021/acs.jafc.9b00228. Epub 2019 Feb 26.


New Bis-Alkenoic Acid Derivatives from a Marine-Derived Fungus Fusarium solani H915.

Liu SZ, Yan X, Tang XX, Lin JG, Qiu YK.

Mar Drugs. 2018 Dec 3;16(12). pii: E483. doi: 10.3390/md16120483.


Microalgal Microscale Model for Microalgal Growth Inhibition Evaluation of Marine Natural Products.

Zhao Q, Chen AN, Hu SX, Liu Q, Chen M, Liu L, Shao CL, Tang XX, Wang CY.

Sci Rep. 2018 Jul 12;8(1):10541. doi: 10.1038/s41598-018-28980-z.


Synthesis, crystal structure and aggregation-induced emission of a new pyrene-based compound, 3,3-diphenyl-2-[4-(pyren-1-yl)phen-yl]acrylo-nitrile.

Miao BX, Tang XX, Zhang LF.

Acta Crystallogr E Crystallogr Commun. 2018 Apr 6;74(Pt 5):638-641. doi: 10.1107/S2056989018005182. eCollection 2018 May 1.


Description of a Zostera marina catalase gene involved in responses to temperature stress.

Zang Y, Liu J, Tang XX, Zhou B.

PeerJ. 2018 Mar 26;6:e4532. doi: 10.7717/peerj.4532. eCollection 2018.


MYC-family protein overexpression and prominent nucleolar formation represent prognostic indicators and potential therapeutic targets for aggressive high-MKI neuroblastomas: a report from the children's oncology group.

Niemas-Teshiba R, Matsuno R, Wang LL, Tang XX, Chiu B, Zeki J, Coburn J, Ornell K, Naranjo A, Van Ryn C, London WB, Hogarty MD, Gastier-Foster JM, Look AT, Park JR, Maris JM, Cohn SL, Seeger RC, Asgharzadeh S, Ikegaki N, Shimada H.

Oncotarget. 2017 Dec 15;9(5):6416-6432. doi: 10.18632/oncotarget.23740. eCollection 2018 Jan 19.


Nominal carbonic anhydrase activity minimizes airway-surface liquid pH changes during breathing.

Thornell IM, Li X, Tang XX, Brommel CM, Karp PH, Welsh MJ, Zabner J.

Physiol Rep. 2018 Jan;6(2). doi: 10.14814/phy2.13569.


Motile cilia of human airway epithelia contain hedgehog signaling components that mediate noncanonical hedgehog signaling.

Mao S, Shah AS, Moninger TO, Ostedgaard LS, Lu L, Tang XX, Thornell IM, Reznikov LR, Ernst SE, Karp PH, Tan P, Keshavjee S, Abou Alaiwa MH, Welsh MJ.

Proc Natl Acad Sci U S A. 2018 Feb 6;115(6):1370-1375. doi: 10.1073/pnas.1719177115. Epub 2018 Jan 22.


High beam quality 5 J, 200 Hz Nd:YAG laser system.

Fan ZW, Qiu JS, Kang ZJ, Chen YZ, Ge WQ, Tang XX.

Light Sci Appl. 2017 Mar 24;6(3):e17004. doi: 10.1038/lsa.2017.4. eCollection 2017 Mar. No abstract available.


[Characterizing Dissolved Organic Matter (DOM) in Wastewater from Scale Pig Farms Using Three-Dimensional Excitation-Emission Matrices (3DEEM].

Li L, Li ZP, Liu M, Ma XY, Tang XX.

Guang Pu Xue Yu Guang Pu Fen Xi. 2017 Feb;37(2):577-83. Chinese.


[Structural Analysis of Organic Matter Composition in Piggery Wastewater during the Process of Organic Degradation Based on FTIR Spectroscopy].

Li L, Li ZP, Liu M, Wu M, Ma XY, Tang XX.

Guang Pu Xue Yu Guang Pu Fen Xi. 2016 Nov;36(11):3517-22. Chinese.


Macrolactins from Marine-Derived Bacillus subtilis B5 Bacteria as Inhibitors of Inducible Nitric Oxide and Cytokines Expression.

Yan X, Zhou YX, Tang XX, Liu XX, Yi ZW, Fang MJ, Wu Z, Jiang FQ, Qiu YK.

Mar Drugs. 2016 Oct 26;14(11). pii: E195.


Two-beam combined 3.36  J, 100  Hz diode-pumped high beam quality Nd:YAG laser system.

Qiu JS, Tang XX, Fan ZW, Wang HC, Liu H.

Appl Opt. 2016 Jul 20;55(21):5630-3. doi: 10.1364/AO.55.005630.


Biosynthetic Functional Gene Analysis of Bis-Indole Metabolites from 25D7, a Clone Derived from a Deep-Sea Sediment Metagenomic Library.

Yan X, Tang XX, Qin D, Yi ZW, Fang MJ, Wu Z, Qiu YK.

Mar Drugs. 2016 Jun 1;14(6). pii: E107. doi: 10.3390/md14060107.


Relationships among CFTR expression, HCO3- secretion, and host defense may inform gene- and cell-based cystic fibrosis therapies.

Shah VS, Ernst S, Tang XX, Karp PH, Parker CP, Ostedgaard LS, Welsh MJ.

Proc Natl Acad Sci U S A. 2016 May 10;113(19):5382-7. doi: 10.1073/pnas.1604905113. Epub 2016 Apr 25.


A new macrolactin antibiotic from deep sea-derived bacteria Bacillus subtilis B5.

Li W, Tang XX, Yan X, Wu Z, Yi ZW, Fang MJ, Su X, Qiu YK.

Nat Prod Res. 2016 Dec;30(24):2777-2782. doi: 10.1080/14786419.2016.1155576. Epub 2016 Apr 13.


Airway acidification initiates host defense abnormalities in cystic fibrosis mice.

Shah VS, Meyerholz DK, Tang XX, Reznikov L, Abou Alaiwa M, Ernst SE, Karp PH, Wohlford-Lenane CL, Heilmann KP, Leidinger MR, Allen PD, Zabner J, McCray PB Jr, Ostedgaard LS, Stoltz DA, Randak CO, Welsh MJ.

Science. 2016 Jan 29;351(6272):503-7. doi: 10.1126/science.aad5589.


Acidic pH increases airway surface liquid viscosity in cystic fibrosis.

Tang XX, Ostedgaard LS, Hoegger MJ, Moninger TO, Karp PH, McMenimen JD, Choudhury B, Varki A, Stoltz DA, Welsh MJ.

J Clin Invest. 2016 Mar 1;126(3):879-91. doi: 10.1172/JCI83922. Epub 2016 Jan 25.


Electrolyte transport properties in distal small airways from cystic fibrosis pigs with implications for host defense.

Li X, Tang XX, Vargas Buonfiglio LG, Comellas AP, Thornell IM, Ramachandran S, Karp PH, Taft PJ, Sheets K, Abou Alaiwa MH, Welsh MJ, Meyerholz DK, Stoltz DA, Zabner J.

Am J Physiol Lung Cell Mol Physiol. 2016 Apr 1;310(7):L670-9. doi: 10.1152/ajplung.00422.2015. Epub 2016 Jan 22.


Peripheral invariant natural killer T cell deficiency in metabolically unhealthy but normal weight versus metabolically healthy but obese individuals.

Wang XL, Chang XY, Tang XX, Chen ZG, Zhou T, Sun K.

J Int Med Res. 2016 Dec;44(6):1272-1282. doi: 10.1177/0300060516663778. Epub 2016 Nov 10.


The status of occupational blood and infectious body fluids exposures in five blood centres in China: a 5-year review.

Wang YJ, Meng ZH, Zheng XF, Tang XX, Sang LY, Du XM, Cheng YZ.

Transfus Med. 2015 Dec;25(6):399-405. doi: 10.1111/tme.12262. Epub 2015 Nov 17.


Constitutive secretion of Interleukin-4 dictates CD133+ side population cells to resist drug treatment and cell death.

Guan GF, Tang XX, Zhang DJ, Zheng Y, Yu DJ, Zhao Y, Lu YQ, Zhu L.

J BUON. 2015 Sep-Oct;20(5):1350-9.


[Diagnostic Significance of BAT in Anaphylaxis to Non-ionic Contrast Media].

Zhang HY, Xu SJ, Tang XX, Niu JJ, Guo XJ, Gao CR.

Fa Yi Xue Za Zhi. 2015 Jun;31(3):188-90. Chinese.


[Extraction of Heavy Metals from Sludge Using Biodegradable Chelating Agent N,N-bis(carboxymethyl) Glutamic Acid Tetrasodium].

Wu Q, Cui YR, Tang XX, Yang HJ, Sun JH.

Huan Jing Ke Xue. 2015 May;36(5):1733-8. Chinese.


Augmented expression of MYC and/or MYCN protein defines highly aggressive MYC-driven neuroblastoma: a Children's Oncology Group study.

Wang LL, Teshiba R, Ikegaki N, Tang XX, Naranjo A, London WB, Hogarty MD, Gastier-Foster JM, Look AT, Park JR, Maris JM, Cohn SL, Seeger RC, Asgharzadeh S, Shimada H.

Br J Cancer. 2015 Jun 30;113(1):57-63. doi: 10.1038/bjc.2015.188. Epub 2015 Jun 2.


Apoptosis-inducing factor and calpain upregulation in glutamate-induced injury of rat spiral ganglion neurons.

Ding ZJ, Chen X, Tang XX, Wang X, Song YL, Chen XD, Wang J, Wang RF, Mi WJ, Chen FQ, Qiu JH.

Mol Med Rep. 2015 Aug;12(2):1685-92. doi: 10.3892/mmr.2015.3626. Epub 2015 Apr 16.


Calpain inhibitor PD150606 attenuates glutamate induced spiral ganglion neuron apoptosis through apoptosis inducing factor pathway in vitro.

Ding ZJ, Chen X, Tang XX, Wang X, Song YL, Chen XD, Mi WJ, Wang J, Lin Y, Chen FQ, Qiu JH.

PLoS One. 2015 Apr 15;10(4):e0123130. doi: 10.1371/journal.pone.0123130. eCollection 2015.


Basic fibroblast growth factor lentiviral vector-transfected sheep bone marrow mesenchymal stem cells and non-specific osteogenic gene expression.

Hu Y, Zhang Q, Zhang L, Tang XX, He HY.

Mol Med Rep. 2015 Jul;12(1):267-72. doi: 10.3892/mmr.2015.3399. Epub 2015 Feb 27.


Medical reversal of chronic sinusitis in a cystic fibrosis patient with ivacaftor.

Chang EH, Tang XX, Shah VS, Launspach JL, Ernst SE, Hilkin B, Karp PH, Abou Alaiwa MH, Graham SM, Hornick DB, Welsh MJ, Stoltz DA, Zabner J.

Int Forum Allergy Rhinol. 2015 Feb;5(2):178-81. doi: 10.1002/alr.21440. Epub 2014 Oct 31.


Fecal lactoferrin in discriminating inflammatory bowel disease from irritable bowel syndrome: a diagnostic meta-analysis.

Zhou XL, Xu W, Tang XX, Luo LS, Tu JF, Zhang CJ, Xu X, Wu QD, Pan WS.

BMC Gastroenterol. 2014 Jul 7;14:121. doi: 10.1186/1471-230X-14-121. Review.


Two new cytotoxic indole alkaloids from a deep-sea sediment derived metagenomic clone.

Yan X, Tang XX, Chen L, Yi ZW, Fang MJ, Wu Z, Qiu YK.

Mar Drugs. 2014 Apr 8;12(4):2156-63. doi: 10.3390/md12042156.


Gene expression during induced differentiation of sheep bone marrow mesenchymal stem cells into osteoblasts.

Hu Y, Tang XX, He HY.

Genet Mol Res. 2013 Dec 11;12(4):6527-34. doi: 10.4238/2013.December.11.4.


Destabilization of MYC/MYCN by the mitochondrial inhibitors, metaiodobenzylguanidine, metformin and phenformin.

Wang SS, Hsiao R, Limpar MM, Lomahan S, Tran TA, Maloney NJ, Ikegaki N, Tang XX.

Int J Mol Med. 2014 Jan;33(1):35-42. doi: 10.3892/ijmm.2013.1545. Epub 2013 Nov 1.


S(+)-ibuprofen destabilizes MYC/MYCN and AKT, increases p53 expression, and induces unfolded protein response and favorable phenotype in neuroblastoma cell lines.

Ikegaki N, Hicks SL, Regan PL, Jacobs J, Jumbo AS, Leonhardt P, Rappaport EF, Tang XX.

Int J Oncol. 2014 Jan;44(1):35-43. doi: 10.3892/ijo.2013.2148. Epub 2013 Oct 25.


Transient treatment with epigenetic modifiers yields stable neuroblastoma stem cells resembling aggressive large-cell neuroblastomas.

Ikegaki N, Shimada H, Fox AM, Regan PL, Jacobs JR, Hicks SL, Rappaport EF, Tang XX.

Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):6097-102. doi: 10.1073/pnas.1118262110. Epub 2013 Mar 11.


Pancreatic and biliary secretion are both altered in cystic fibrosis pigs.

Uc A, Giriyappa R, Meyerholz DK, Griffin M, Ostedgaard LS, Tang XX, Abu-El-Haija M, Stoltz DA, Ludwig P, Pezzulo A, Abu-El-Haija M, Taft P, Welsh MJ.

Am J Physiol Gastrointest Liver Physiol. 2012 Oct 15;303(8):G961-8. doi: 10.1152/ajpgi.00030.2012. Epub 2012 Aug 30.


[Predictability of the corneal flap creation with the femtosecond laser in LASIK].

Mai ZB, Liu SB, Nie XL, Sun HX, Xin BL, Tang XX.

Zhonghua Yan Ke Za Zhi. 2012 May;48(5):390-3. Chinese.


Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung.

Pezzulo AA, Tang XX, Hoegger MJ, Abou Alaiwa MH, Ramachandran S, Moninger TO, Karp PH, Wohlford-Lenane CL, Haagsman HP, van Eijk M, Bánfi B, Horswill AR, Stoltz DA, McCray PB Jr, Welsh MJ, Zabner J.

Nature. 2012 Jul 4;487(7405):109-13. doi: 10.1038/nature11130.


Lymphocyte CFTR promotes epithelial bicarbonate secretion for bacterial killing.

Tang XX, Fok KL, Chen H, Chan KS, Tsang LL, Rowlands DK, Zhang XH, Dong JD, Ruan YC, Jiang X, Yu SS, Chung YW, Chan HC.

J Cell Physiol. 2012 Dec;227(12):3887-94. doi: 10.1002/jcp.24101.


Two new compounds from marine-derived fungus Penicillium sp. F11.

Zhuang P, Tang XX, Yi ZW, Qiu YK, Wu Z.

J Asian Nat Prod Res. 2012;14(3):197-203. doi: 10.1080/10286020.2011.634279. Epub 2012 Jan 16.


Expression of a neurotoxin gene improves the insecticidal activity of Spodoptera litura nucleopolyhedrovirus (SpltNPV).

Tang XX, Sun XL, Pu GQ, Wang WB, Zhang CX, Zhu J.

Virus Res. 2011 Jul;159(1):51-6. doi: 10.1016/j.virusres.2011.04.025. Epub 2011 May 6.


A novel indole alkaloid from deep-sea sediment metagenomic clone-derived Escherichia coli fermentation broth.

Chen L, Tang XX, Zheng M, Yi ZW, Xiao X, Qiu YK, Wu Z.

J Asian Nat Prod Res. 2011 May;13(5):444-8. doi: 10.1080/10286020.2011.570262.


Apoptosis induced by yessotoxins in Hela human cervical cancer cells in vitro.

Pang M, Gao CL, Wu ZX, Lv N, Wang ZL, Tang XX, Qu P.

Mol Med Rep. 2010 Jul-Aug;3(4):629-34. doi: 10.3892/mmr_00000307.


Hsp90 inhibition increases p53 expression and destabilizes MYCN and MYC in neuroblastoma.

Regan PL, Jacobs J, Wang G, Torres J, Edo R, Friedmann J, Tang XX.

Int J Oncol. 2011 Jan;38(1):105-12.


Biological effects of induced MYCN hyper-expression in MYCN-amplified neuroblastomas.

Torres J, Regan PL, Edo R, Leonhardt P, Jeng EI, Rappaport EF, Ikegaki N, Tang XX.

Int J Oncol. 2010 Oct;37(4):983-91.


Lymphocytes accelerate epithelial tight junction assembly: role of AMP-activated protein kinase (AMPK).

Tang XX, Chen H, Yu S, Zhang L, Caplan MJ, Chan HC.

PLoS One. 2010 Aug 23;5(8):e12343. doi: 10.1371/journal.pone.0012343.

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