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Items: 43


Differences in lung cancer characteristics and mortality rate between screened and non-screened cohorts.

Wu FZ, Kuo PL, Huang YL, Tang EK, Chen CS, Wu MT, Lin YP.

Sci Rep. 2019 Dec 18;9(1):19386. doi: 10.1038/s41598-019-56025-6.


Synthesis of TPGS/Curcumin Nanoparticles by Thin-Film Hydration and Evaluation of Their Anti-Colon Cancer Efficacy In Vitro and In Vivo.

Li H, Yan L, Tang EKY, Zhang Z, Chen W, Liu G, Mo J.

Front Pharmacol. 2019 Jul 12;10:769. doi: 10.3389/fphar.2019.00769. eCollection 2019.


Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen.

Menden MP, Wang D, Mason MJ, Szalai B, Bulusu KC, Guan Y, Yu T, Kang J, Jeon M, Wolfinger R, Nguyen T, Zaslavskiy M; AstraZeneca-Sanger Drug Combination DREAM Consortium, Jang IS, Ghazoui Z, Ahsen ME, Vogel R, Neto EC, Norman T, Tang EKY, Garnett MJ, Veroli GYD, Fawell S, Stolovitzky G, Guinney J, Dry JR, Saez-Rodriguez J.

Nat Commun. 2019 Jun 17;10(1):2674. doi: 10.1038/s41467-019-09799-2.


Protective effects of novel derivatives of vitamin D3 and lumisterol against UVB-induced damage in human keratinocytes involve activation of Nrf2 and p53 defense mechanisms.

Chaiprasongsuk A, Janjetovic Z, Kim TK, Jarrett SG, D'Orazio JA, Holick MF, Tang EKY, Tuckey RC, Panich U, Li W, Slominski AT.

Redox Biol. 2019 Jun;24:101206. doi: 10.1016/j.redox.2019.101206. Epub 2019 Apr 20.


Catalytic properties of 25-hydroxyvitamin D3 3-epimerase in rat and human liver microsomes.

Tuckey RC, Tang EKY, Maresse SR, Delaney DS.

Arch Biochem Biophys. 2019 May 15;666:16-21. doi: 10.1016/ Epub 2019 Mar 27.


A rare presentation of pleomorphic carcinoma of lung mimic empyema.

Yang KM, Tang EK, Goan YG, Tseng YC.

Ann Transl Med. 2019 Feb;7(3):52. doi: 10.21037/atm.2018.12.19.


Bronchoscopic cryosurgery for metastatic tumor causing central airway obstruction: A case report.

Chen TY, Goan YG, Tang EK, Tseng YC.

Medicine (Baltimore). 2019 Mar;98(9):e14635. doi: 10.1097/MD.0000000000014635.


Benign Metastasising Leiomyomatosis of the Lung Presenting as Progressive Pneumothorax.

Tang EK, Wu FZ.

Heart Lung Circ. 2019 Apr;28(4):e94-e95. doi: 10.1016/j.hlc.2018.10.014. Epub 2018 Oct 26. No abstract available.


Natural History of Persistent Pulmonary Subsolid Nodules: Long-Term Observation of Different Interval Growth.

Tang EK, Chen CS, Wu CC, Wu MT, Yang TL, Liang HL, Hsu HT, Wu FZ.

Heart Lung Circ. 2019 Nov;28(11):1747-1754. doi: 10.1016/j.hlc.2018.08.015. Epub 2018 Sep 14.


A new application for argon beam coagulation: the thymoma patient with pleural recurrence.

Tseng YC, Tseng YH, Tang EK, Goan YG.

J Thorac Dis. 2018 May;10(5):E355-E358. doi: 10.21037/jtd.2018.04.114.


A novel, palatable paediatric oral formulation of midazolam: pharmacokinetics, tolerability, efficacy and safety.

Salman S, Tang EKY, Cheung LC, Nguyen MN, Sommerfield D, Slevin L, Lim LY, von Ungern Sternberg BS.

Anaesthesia. 2018 Dec;73(12):1469-1477. doi: 10.1111/anae.14318. Epub 2018 Jul 9.


Modified Lung-RADS Improves Performance of Screening LDCT in a Population with High Prevalence of Non-smoking-related Lung Cancer.

Hsu HT, Tang EK, Wu MT, Wu CC, Liang CH, Chen CS, Mar GY, Lai RS, Wang JC, Wu CL, Huang YL, Wu FZ.

Acad Radiol. 2018 Oct;25(10):1240-1251. doi: 10.1016/j.acra.2018.01.012. Epub 2018 Mar 9.


Qualitative CT Criterion for Subsolid Nodule Subclassification: Improving Interobserver Agreement and Pathologic Correlation in the Adenocarcinoma Spectrum.

Chen PA, Huang EP, Shih LY, Tang EK, Chien CC, Wu MT, Wu FZ.

Acad Radiol. 2018 Nov;25(11):1439-1445. doi: 10.1016/j.acra.2018.01.011. Epub 2018 Mar 9.


Semiquantative Visual Assessment of Sub-solid Pulmonary Nodules ≦3 cm in Differentiation of Lung Adenocarcinoma Spectrum.

Wu FZ, Chen PA, Wu CC, Kuo PL, Tsao SP, Chien CC, Tang EK, Wu MT.

Sci Rep. 2017 Nov 17;7(1):15790. doi: 10.1038/s41598-017-16042-9.


1α,20S-Dihydroxyvitamin D3 Interacts with Vitamin D Receptor: Crystal Structure and Route of Chemical Synthesis.

Lin Z, Chen H, Belorusova AY, Bollinger JC, Tang EKY, Janjetovic Z, Kim TK, Wu Z, Miller DD, Slominski AT, Postlethwaite AE, Tuckey RC, Rochel N, Li W.

Sci Rep. 2017 Aug 31;7(1):10193. doi: 10.1038/s41598-017-10917-7.


Dumbbell-Mimicked Mediastinal Angiomatosis.

Tang EK, Chu PT, Goan YG, Hsieh PP, Lin JC.

Ann Thorac Surg. 2016 Dec;102(6):e555-e556. doi: 10.1016/j.athoracsur.2016.05.051.


Endogenously produced nonclassical vitamin D hydroxy-metabolites act as "biased" agonists on VDR and inverse agonists on RORα and RORγ.

Slominski AT, Kim TK, Hobrath JV, Oak ASW, Tang EKY, Tieu EW, Li W, Tuckey RC, Jetten AM.

J Steroid Biochem Mol Biol. 2017 Oct;173:42-56. doi: 10.1016/j.jsbmb.2016.09.024. Epub 2016 Sep 28. Review.


Assessment of Selection Criteria for Low-Dose Lung Screening CT Among Asian Ethnic Groups in Taiwan: From Mass Screening to Specific Risk-Based Screening for Non-Smoker Lung Cancer.

Wu FZ, Huang YL, Wu CC, Tang EK, Chen CS, Mar GY, Yen Y, Wu MT.

Clin Lung Cancer. 2016 Sep;17(5):e45-e56. doi: 10.1016/j.cllc.2016.03.004. Epub 2016 Mar 30.


Hemocompatibility evaluation for peptide fragments of human serum albumin cleaved by cyanogens bromide.

Wu XJ, Tang EK, Xu CQ, Yuan ZX.

J Biomater Appl. 2016 Feb;30(7):974-82. doi: 10.1177/0885328215608018. Epub 2015 Oct 18.


Detection of novel CYP11A1-derived secosteroids in the human epidermis and serum and pig adrenal gland.

Slominski AT, Kim TK, Li W, Postlethwaite A, Tieu EW, Tang EKY, Tuckey RC.

Sci Rep. 2015 Oct 8;5:14875. doi: 10.1038/srep14875.


Caspase-8 activation by TRAIL monotherapy predicts responses to IAPi and TRAIL combination treatment in breast cancer cell lines.

Polanski R, Vincent J, Polanska UM, Petreus T, Tang EK.

Cell Death Dis. 2015 Oct 1;6:e1893. doi: 10.1038/cddis.2015.234.


Kinetic analysis of human CYP24A1 metabolism of vitamin D via the C24-oxidation pathway.

Tieu EW, Tang EK, Tuckey RC.

FEBS J. 2014 Jul;281(14):3280-96. doi: 10.1111/febs.12862. Epub 2014 Jun 25.


Novel vitamin D analogs as potential therapeutics: metabolism, toxicity profiling, and antiproliferative activity.

Chen J, Wang J, Kim TK, Tieu EW, Tang EK, Lin Z, Kovacic D, Miller DD, Postlethwaite A, Tuckey RC, Slominski AT, Li W.

Anticancer Res. 2014 May;34(5):2153-63.


In vivo production of novel vitamin D2 hydroxy-derivatives by human placentas, epidermal keratinocytes, Caco-2 colon cells and the adrenal gland.

Slominski AT, Kim TK, Shehabi HZ, Tang EK, Benson HA, Semak I, Lin Z, Yates CR, Wang J, Li W, Tuckey RC.

Mol Cell Endocrinol. 2014 Mar 5;383(1-2):181-92. doi: 10.1016/j.mce.2013.12.012. Epub 2013 Dec 29.


Hydroxylation of CYP11A1-derived products of vitamin D3 metabolism by human and mouse CYP27B1.

Tang EK, Chen J, Janjetovic Z, Tieu EW, Slominski AT, Li W, Tuckey RC.

Drug Metab Dispos. 2013 May;41(5):1112-24. doi: 10.1124/dmd.113.050955. Epub 2013 Mar 1.


An uncommon cause of esophageal ulcer: a diagnostic pitfall.

Chiu HY, Tang EK, Chang HC, Goan YG.

Gastrointest Endosc. 2013 Feb;77(2):294-6. doi: 10.1016/j.gie.2012.09.019. Epub 2012 Nov 20. No abstract available.


Rat CYP24A1 acts on 20-hydroxyvitamin D(3) producing hydroxylated products with increased biological activity.

Tieu EW, Tang EK, Chen J, Li W, Nguyen MN, Janjetovic Z, Slominski A, Tuckey RC.

Biochem Pharmacol. 2012 Dec 15;84(12):1696-704. doi: 10.1016/j.bcp.2012.09.032. Epub 2012 Oct 5.


Expression of human CYP27B1 in Escherichia coli and characterization in phospholipid vesicles.

Tang EKY, Tieu EW, Tuckey RC.

FEBS J. 2012 Oct;279(19):3749-3761. doi: 10.1111/j.1742-4658.2012.08736.x. Epub 2012 Aug 28.


In vivo evidence for a novel pathway of vitamin D₃ metabolism initiated by P450scc and modified by CYP27B1.

Slominski AT, Kim TK, Shehabi HZ, Semak I, Tang EK, Nguyen MN, Benson HA, Korik E, Janjetovic Z, Chen J, Yates CR, Postlethwaite A, Li W, Tuckey RC.

FASEB J. 2012 Sep;26(9):3901-15. doi: 10.1096/fj.12-208975. Epub 2012 Jun 8.


Correlation between secosteroid-induced vitamin D receptor activity in melanoma cells and computer-modeled receptor binding strength.

Kim TK, Wang J, Janjetovic Z, Chen J, Tuckey RC, Nguyen MN, Tang EK, Miller D, Li W, Slominski AT.

Mol Cell Endocrinol. 2012 Sep 25;361(1-2):143-52. doi: 10.1016/j.mce.2012.04.001. Epub 2012 Apr 21.


Design, synthesis, and biological action of 20R-hydroxyvitamin D3.

Lu Y, Chen J, Janjetovic Z, Michaels P, Tang EK, Wang J, Tuckey RC, Slominski AT, Li W, Miller DD.

J Med Chem. 2012 Apr 12;55(7):3573-7. doi: 10.1021/jm201478e. Epub 2012 Mar 20.


20-Hydroxyvitamin D2 is a noncalcemic analog of vitamin D with potent antiproliferative and prodifferentiation activities in normal and malignant cells.

Slominski AT, Kim TK, Janjetovic Z, Tuckey RC, Bieniek R, Yue J, Li W, Chen J, Nguyen MN, Tang EK, Miller D, Chen TC, Holick M.

Am J Physiol Cell Physiol. 2011 Mar;300(3):C526-41. doi: 10.1152/ajpcell.00203.2010. Epub 2010 Dec 15.


Purified mouse CYP27B1 can hydroxylate 20,23-dihydroxyvitamin D3, producing 1alpha,20,23-trihydroxyvitamin D3, which has altered biological activity.

Tang EK, Li W, Janjetovic Z, Nguyen MN, Wang Z, Slominski A, Tuckey RC.

Drug Metab Dispos. 2010 Sep;38(9):1553-9. doi: 10.1124/dmd.110.034389. Epub 2010 Jun 16.


Metabolism of substrates incorporated into phospholipid vesicles by mouse 25-hydroxyvitamin D3 1alpha-hydroxylase (CYP27B1).

Tang EK, Voo KJ, Nguyen MN, Tuckey RC.

J Steroid Biochem Mol Biol. 2010 Apr;119(3-5):171-9. doi: 10.1016/j.jsbmb.2010.02.022. Epub 2010 Mar 1.


Predicting stature from knee height in Chinese elderly subjects.

Li ET, Tang EK, Wong CY, Lui SS, Chan VY, Dai DL.

Asia Pac J Clin Nutr. 2000 Dec;9(4):252-5.


New non-peptide endothelin-A receptor antagonists: synthesis, biological properties, and structure-activity relationships of 5-(dimethylamino)-N-pyridyl-,-N-pyrimidinyl-,-N-pyridazinyl-, and -N-pyrazinyl-1-naphthalenesulfonamides.

Bradbury RH, Bath C, Butlin RJ, Dennis M, Heys C, Hunt SJ, James R, Mortlock AA, Sumner NF, Tang EK, Telford B, Whiting E, Wilson C.

J Med Chem. 1997 Mar 14;40(6):996-1004.


Cell-based assay for functional screening of compounds active at the human endothelin A receptor.

McLean JS, Kruger H, Swift D, Tang EK, Brennand JC.

J Cardiovasc Pharmacol. 1995 Dec;26(6):978-82.


Structural features of tracheal tube biofilm formed during prolonged mechanical ventilation.

Inglis TJ, Lim TM, Ng ML, Tang EK, Hui KP.

Chest. 1995 Oct;108(4):1049-52.


Cytoskeletal proteolysis during calcium-induced morphological transitions of human erythrocytes.

Whatmore JL, Tang EK, Hickman JA.

Exp Cell Res. 1992 Jun;200(2):316-25.


Identification of two cAMP-dependent phosphorylation sites on erythrocyte protein 4.1.

Horne WC, Prinz WC, Tang EK.

Biochim Biophys Acta. 1990 Oct 15;1055(1):87-92.


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