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Items: 1 to 50 of 95

1.

Study profile of The Tohoku Medical Megabank Community-Based Cohort Study.

Hozawa A, Tanno K, Nakaya N, Nakamura T, Tsuchiya N, Hirata T, Narita A, Kogure M, Nochioka K, Sasaki R, Takanashi N, Otsuka K, Sakata K, Kuriyama S, Kikuya M, Tanabe O, Sugawara J, Suzuki K, Suzuki Y, Kodama EN, Fuse N, Kiyomoto H, Tomita H, Uruno A, Hamanaka Y, Metoki H, Ishikuro M, Obara T, Kobayashi T, Kitatani K, Takai-Igarashi T, Ogishima S, Satoh M, Ohmomo H, Tsuboi A, Egawa S, Ishii T, Ito K, Ito S, Taki Y, Minegishi N, Ishii N, Nagasaki M, Igarashi K, Koshiba S, Shimizu R, Tamiya G, Nakayama K, Motohashi H, Yasuda J, Shimizu A, Hachiya T, Shiwa Y, Tominaga T, Tanaka H, Oyama K, Tanaka R, Kawame H, Fukushima A, Ishigaki Y, Tokutomi T, Osumi N, Kobayashi T, Nagami F, Hashizume H, Arai T, Kawaguchi Y, Higuchi S, Sakaida M, Endo R, Nishizuka S, Tsuji I, Hitomi J, Nakamura M, Ogasawara K, Yaegashi N, Kinoshita K, Kure S, Sakai A, Kobayashi S, Sobue K, Sasaki M, Yamamoto M.

J Epidemiol. 2020 Jan 11. doi: 10.2188/jea.JE20190271. [Epub ahead of print]

2.

Cohort Profile: Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study): Rationale, Progress and Perspective.

Kuriyama S, Metoki H, Kikuya M, Obara T, Ishikuro M, Yamanaka C, Nagai M, Matsubara H, Kobayashi T, Sugawara J, Tamiya G, Hozawa A, Nakaya N, Tsuchiya N, Nakamura T, Narita A, Kogure M, Hirata T, Tsuji I, Nagami F, Fuse N, Arai T, Kawaguchi Y, Higuchi S, Sakaida M, Suzuki Y, Osumi N, Nakayama K, Ito K, Egawa S, Chida K, Kodama E, Kiyomoto H, Ishii T, Tsuboi A, Tomita H, Taki Y, Kawame H, Suzuki K, Ishii N, Ogishima S, Mizuno S, Takai-Igarashi T, Minegishi N, Yasuda J, Igarashi K, Shimizu R, Nagasaki M, Tanabe O, Koshiba S, Hashizume H, Motohashi H, Tominaga T, Ito S, Tanno K, Sakata K, Shimizu A, Hitomi J, Sasaki M, Kinoshita K, Tanaka H, Kobayashi T, Kure S, Yaegashi N, Yamamoto M; Tohoku Medical Megabank Project Study Group .

Int J Epidemiol. 2019 Aug 25. pii: dyz169. doi: 10.1093/ije/dyz169. [Epub ahead of print] No abstract available.

PMID:
31504573
3.

A single nucleotide polymorphism (-250 A/C) of the GFAP gene is associated with brain structures and cerebral blood flow.

Takahashi Y, Takeuchi H, Sakai M, Yu Z, Kikuchi Y, Ito F, Matsuoka H, Tanabe O, Yasuda J, Taki Y, Kawashima R, Tomita H.

Psychiatry Clin Neurosci. 2020 Jan;74(1):49-55. doi: 10.1111/pcn.12932. Epub 2019 Oct 16.

PMID:
31503390
4.

Construction of JRG (Japanese reference genome) with single-molecule real-time sequencing.

Nagasaki M, Kuroki Y, Shibata TF, Katsuoka F, Mimori T, Kawai Y, Minegishi N, Hozawa A, Kuriyama S, Suzuki Y, Kawame H, Nagami F, Takai-Igarashi T, Ogishima S, Kojima K, Misawa K, Tanabe O, Fuse N, Tanaka H, Yaegashi N, Kinoshita K, Kure S, Yasuda J, Yamamoto M.

Hum Genome Var. 2019 Jun 7;6:27. doi: 10.1038/s41439-019-0057-7. eCollection 2019.

5.

Estimating carrier frequencies of newborn screening disorders using a whole-genome reference panel of 3552 Japanese individuals.

Yamaguchi-Kabata Y, Yasuda J, Uruno A, Shimokawa K, Koshiba S, Suzuki Y, Fuse N, Kawame H, Tadaka S, Nagasaki M, Kojima K, Katsuoka F, Kumada K, Tanabe O, Tamiya G, Yaegashi N, Kinoshita K, Yamamoto M, Kure S; Tohoku Medical Megabank Project Study Group.

Hum Genet. 2019 Apr;138(4):389-409. doi: 10.1007/s00439-019-01998-7. Epub 2019 Mar 18.

PMID:
30887117
6.

Maternity Log study: a longitudinal lifelog monitoring and multiomics analysis for the early prediction of complicated pregnancy.

Sugawara J, Ochi D, Yamashita R, Yamauchi T, Saigusa D, Wagata M, Obara T, Ishikuro M, Tsunemoto Y, Harada Y, Shibata T, Mimori T, Kawashima J, Katsuoka F, Igarashi-Takai T, Ogishima S, Metoki H, Hashizume H, Fuse N, Minegishi N, Koshiba S, Tanabe O, Kuriyama S, Kinoshita K, Kure S, Yaegashi N, Yamamoto M, Hiyama S, Nagasaki M.

BMJ Open. 2019 Feb 19;9(2):e025939. doi: 10.1136/bmjopen-2018-025939.

7.

Genome analyses for the Tohoku Medical Megabank Project towards establishment of personalized healthcare.

Yasuda J, Kinoshita K, Katsuoka F, Danjoh I, Sakurai-Yageta M, Motoike IN, Kuroki Y, Saito S, Kojima K, Shirota M, Saigusa D, Otsuki A, Kawashima J, Yamaguchi-Kabata Y, Tadaka S, Aoki Y, Mimori T, Kumada K, Inoue J, Makino S, Kuriki M, Fuse N, Koshiba S, Tanabe O, Nagasaki M, Tamiya G, Shimizu R, Takai-Igarashi T, Ogishima S, Hozawa A, Kuriyama S, Sugawara J, Tsuboi A, Kiyomoto H, Ishii T, Tomita H, Minegishi N, Suzuki Y, Suzuki K, Kawame H, Tanaka H, Taki Y, Yaegashi N, Kure S, Nagami F; Tohoku Medical Megabank Project Study Group, Kosaki K, Sutoh Y, Hachiya T, Shimizu A, Sasaki M, Yamamoto M.

J Biochem. 2019 Feb 1;165(2):139-158. doi: 10.1093/jb/mvy096.

PMID:
30452759
8.

Long non-coding RNA-dependent mechanism to regulate heme biosynthesis and erythrocyte development.

Liu J, Li Y, Tong J, Gao J, Guo Q, Zhang L, Wang B, Zhao H, Wang H, Jiang E, Kurita R, Nakamura Y, Tanabe O, Engel JD, Bresnick EH, Zhou J, Shi L.

Nat Commun. 2018 Oct 22;9(1):4386. doi: 10.1038/s41467-018-06883-x.

9.

Regional genetic differences among Japanese populations and performance of genotype imputation using whole-genome reference panel of the Tohoku Medical Megabank Project.

Yasuda J, Katsuoka F, Danjoh I, Kawai Y, Kojima K, Nagasaki M, Saito S, Yamaguchi-Kabata Y, Tadaka S, Motoike IN, Kumada K, Sakurai-Yageta M, Tanabe O, Fuse N, Tamiya G, Higasa K, Matsuda F, Yasuda N, Iwasaki M, Sasaki M, Shimizu A, Kinoshita K, Yamamoto M.

BMC Genomics. 2018 Jul 24;19(1):551. doi: 10.1186/s12864-018-4942-0.

10.

Omics research project on prospective cohort studies from the Tohoku Medical Megabank Project.

Koshiba S, Motoike I, Saigusa D, Inoue J, Shirota M, Katoh Y, Katsuoka F, Danjoh I, Hozawa A, Kuriyama S, Minegishi N, Nagasaki M, Takai-Igarashi T, Ogishima S, Fuse N, Kure S, Tamiya G, Tanabe O, Yasuda J, Kinoshita K, Yamamoto M.

Genes Cells. 2018 Jun;23(6):406-417. doi: 10.1111/gtc.12588. Epub 2018 Apr 27. Review.

11.

Polymorphisms in the microglial marker molecule CX3CR1 affect the blood volume of the human brain.

Sakai M, Takeuchi H, Yu Z, Kikuchi Y, Ono C, Takahashi Y, Ito F, Matsuoka H, Tanabe O, Yasuda J, Taki Y, Kawashima R, Tomita H.

Psychiatry Clin Neurosci. 2018 Jun;72(6):409-422. doi: 10.1111/pcn.12649. Epub 2018 Apr 10.

12.

Evaluation of reported pathogenic variants and their frequencies in a Japanese population based on a whole-genome reference panel of 2049 individuals.

Yamaguchi-Kabata Y, Yasuda J, Tanabe O, Suzuki Y, Kawame H, Fuse N, Nagasaki M, Kawai Y, Kojima K, Katsuoka F, Saito S, Danjoh I, Motoike IN, Yamashita R, Koshiba S, Saigusa D, Tamiya G, Kure S, Yaegashi N, Kawaguchi Y, Nagami F, Kuriyama S, Sugawara J, Minegishi N, Hozawa A, Ogishima S, Kiyomoto H, Takai-Igarashi T; ToMMo Study Group, Kinoshita K, Yamamoto M.

J Hum Genet. 2018 Feb;63(2):213-230. doi: 10.1038/s10038-017-0347-1. Epub 2017 Dec 1.

PMID:
29192238
13.

The orphan nuclear receptor TR4 regulates erythroid cell proliferation and maturation.

Lee MP, Tanabe O, Shi L, Jearawiriyapaisarn N, Lucas D, Engel JD.

Blood. 2017 Dec 7;130(23):2537-2547. doi: 10.1182/blood-2017-05-783159. Epub 2017 Oct 10.

14.

Establishment of Protocols for Global Metabolomics by LC-MS for Biomarker Discovery.

Saigusa D, Okamura Y, Motoike IN, Katoh Y, Kurosawa Y, Saijyo R, Koshiba S, Yasuda J, Motohashi H, Sugawara J, Tanabe O, Kinoshita K, Yamamoto M.

PLoS One. 2016 Aug 31;11(8):e0160555. doi: 10.1371/journal.pone.0160555. eCollection 2016.

15.

The structural origin of metabolic quantitative diversity.

Koshiba S, Motoike I, Kojima K, Hasegawa T, Shirota M, Saito T, Saigusa D, Danjoh I, Katsuoka F, Ogishima S, Kawai Y, Yamaguchi-Kabata Y, Sakurai M, Hirano S, Nakata J, Motohashi H, Hozawa A, Kuriyama S, Minegishi N, Nagasaki M, Takai-Igarashi T, Fuse N, Kiyomoto H, Sugawara J, Suzuki Y, Kure S, Yaegashi N, Tanabe O, Kinoshita K, Yasuda J, Yamamoto M.

Sci Rep. 2016 Aug 16;6:31463. doi: 10.1038/srep31463.

16.

The Tohoku Medical Megabank Project: Design and Mission.

Kuriyama S, Yaegashi N, Nagami F, Arai T, Kawaguchi Y, Osumi N, Sakaida M, Suzuki Y, Nakayama K, Hashizume H, Tamiya G, Kawame H, Suzuki K, Hozawa A, Nakaya N, Kikuya M, Metoki H, Tsuji I, Fuse N, Kiyomoto H, Sugawara J, Tsuboi A, Egawa S, Ito K, Chida K, Ishii T, Tomita H, Taki Y, Minegishi N, Ishii N, Yasuda J, Igarashi K, Shimizu R, Nagasaki M, Koshiba S, Kinoshita K, Ogishima S, Takai-Igarashi T, Tominaga T, Tanabe O, Ohuchi N, Shimosegawa T, Kure S, Tanaka H, Ito S, Hitomi J, Tanno K, Nakamura M, Ogasawara K, Kobayashi S, Sakata K, Satoh M, Shimizu A, Sasaki M, Endo R, Sobue K, Tohoku Medical Megabank Project Study Group T, Yamamoto M.

J Epidemiol. 2016 Sep 5;26(9):493-511. doi: 10.2188/jea.JE20150268. Epub 2016 Jul 2.

17.

Amelioration of inflammation and tissue damage in sickle cell model mice by Nrf2 activation.

Keleku-Lukwete N, Suzuki M, Otsuki A, Tsuchida K, Katayama S, Hayashi M, Naganuma E, Moriguchi T, Tanabe O, Engel JD, Imaizumi M, Yamamoto M.

Proc Natl Acad Sci U S A. 2015 Sep 29;112(39):12169-74. doi: 10.1073/pnas.1509158112. Epub 2015 Sep 14.

18.

Rare variant discovery by deep whole-genome sequencing of 1,070 Japanese individuals.

Nagasaki M, Yasuda J, Katsuoka F, Nariai N, Kojima K, Kawai Y, Yamaguchi-Kabata Y, Yokozawa J, Danjoh I, Saito S, Sato Y, Mimori T, Tsuda K, Saito R, Pan X, Nishikawa S, Ito S, Kuroki Y, Tanabe O, Fuse N, Kuriyama S, Kiyomoto H, Hozawa A, Minegishi N, Douglas Engel J, Kinoshita K, Kure S, Yaegashi N; ToMMo Japanese Reference Panel Project, Yamamoto M.

Nat Commun. 2015 Aug 21;6:8018. doi: 10.1038/ncomms9018.

19.

Compound loss of function of nuclear receptors Tr2 and Tr4 leads to induction of murine embryonic β-type globin genes.

Cui S, Tanabe O, Sierant M, Shi L, Campbell A, Lim KC, Engel JD.

Blood. 2015 Feb 26;125(9):1477-87. doi: 10.1182/blood-2014-10-605022. Epub 2015 Jan 5.

20.

Validation of multiple single nucleotide variation calls by additional exome analysis with a semiconductor sequencer to supplement data of whole-genome sequencing of a human population.

Motoike IN, Matsumoto M, Danjoh I, Katsuoka F, Kojima K, Nariai N, Sato Y, Yamaguchi-Kabata Y, Ito S, Kudo H, Nishijima I, Nishikawa S, Pan X, Saito R, Saito S, Saito T, Shirota M, Tsuda K, Yokozawa J, Igarashi K, Minegishi N, Tanabe O, Fuse N, Nagasaki M, Kinoshita K, Yasuda J, Yamamoto M.

BMC Genomics. 2014 Aug 10;15:673. doi: 10.1186/1471-2164-15-673.

21.

Biased, non-equivalent gene-proximal and -distal binding motifs of orphan nuclear receptor TR4 in primary human erythroid cells.

Shi L, Sierant MC, Gurdziel K, Zhu F, Cui S, Kolodziej KE, Strouboulis J, Guan Y, Tanabe O, Lim KC, Engel JD.

PLoS Genet. 2014 May 8;10(5):e1004339. doi: 10.1371/journal.pgen.1004339. eCollection 2014 May.

22.

Developmental transcriptome analysis of human erythropoiesis.

Shi L, Lin YH, Sierant MC, Zhu F, Cui S, Guan Y, Sartor MA, Tanabe O, Lim KC, Engel JD.

Hum Mol Genet. 2014 Sep 1;23(17):4528-42. doi: 10.1093/hmg/ddu167. Epub 2014 Apr 29.

23.

PGC-1 coactivator activity is required for murine erythropoiesis.

Cui S, Tanabe O, Lim KC, Xu HE, Zhou XE, Lin JD, Shi L, Schmidt L, Campbell A, Shimizu R, Yamamoto M, Engel JD.

Mol Cell Biol. 2014 Jun;34(11):1956-65. doi: 10.1128/MCB.00247-14. Epub 2014 Mar 24.

24.

TRIM28 is essential for erythroblast differentiation in the mouse.

Hosoya T, Clifford M, Losson R, Tanabe O, Engel JD.

Blood. 2013 Nov 28;122(23):3798-807. doi: 10.1182/blood-2013-04-496166. Epub 2013 Oct 3.

25.

Disruption of the Hbs1l-Myb locus causes hereditary persistence of fetal hemoglobin in a mouse model.

Suzuki M, Yamazaki H, Mukai HY, Motohashi H, Shi L, Tanabe O, Engel JD, Yamamoto M.

Mol Cell Biol. 2013 Apr;33(8):1687-95. doi: 10.1128/MCB.01617-12. Epub 2013 Feb 19.

26.

Lysine-specific demethylase 1 is a therapeutic target for fetal hemoglobin induction.

Shi L, Cui S, Engel JD, Tanabe O.

Nat Med. 2013 Mar;19(3):291-4. doi: 10.1038/nm.3101. Epub 2013 Feb 17.

27.

The TRK-fused gene is mutated in hereditary motor and sensory neuropathy with proximal dominant involvement.

Ishiura H, Sako W, Yoshida M, Kawarai T, Tanabe O, Goto J, Takahashi Y, Date H, Mitsui J, Ahsan B, Ichikawa Y, Iwata A, Yoshino H, Izumi Y, Fujita K, Maeda K, Goto S, Koizumi H, Morigaki R, Ikemura M, Yamauchi N, Murayama S, Nicholson GA, Ito H, Sobue G, Nakagawa M, Kaji R, Tsuji S.

Am J Hum Genet. 2012 Aug 10;91(2):320-9. doi: 10.1016/j.ajhg.2012.07.014.

28.

Forced TR2/TR4 expression in sickle cell disease mice confers enhanced fetal hemoglobin synthesis and alleviated disease phenotypes.

Campbell AD, Cui S, Shi L, Urbonya R, Mathias A, Bradley K, Bonsu KO, Douglas RR, Halford B, Schmidt L, Harro D, Giacherio D, Tanimoto K, Tanabe O, Engel JD.

Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):18808-13. doi: 10.1073/pnas.1104964108. Epub 2011 Oct 31.

29.

Nuclear receptors TR2 and TR4 recruit multiple epigenetic transcriptional corepressors that associate specifically with the embryonic β-type globin promoters in differentiated adult erythroid cells.

Cui S, Kolodziej KE, Obara N, Amaral-Psarris A, Demmers J, Shi L, Engel JD, Grosveld F, Strouboulis J, Tanabe O.

Mol Cell Biol. 2011 Aug;31(16):3298-311. doi: 10.1128/MCB.05310-11. Epub 2011 Jun 13.

30.

Genome-wide binding of the orphan nuclear receptor TR4 suggests its general role in fundamental biological processes.

O'Geen H, Lin YH, Xu X, Echipare L, Komashko VM, He D, Frietze S, Tanabe O, Shi L, Sartor MA, Engel JD, Farnham PJ.

BMC Genomics. 2010 Dec 2;11:689. doi: 10.1186/1471-2164-11-689.

31.

The orphan nuclear receptor TR4 is a vitamin A-activated nuclear receptor.

Zhou XE, Suino-Powell KM, Xu Y, Chan CW, Tanabe O, Kruse SW, Reynolds R, Engel JD, Xu HE.

J Biol Chem. 2011 Jan 28;286(4):2877-85. doi: 10.1074/jbc.M110.168740. Epub 2010 Nov 9.

32.

FIP200 is required for the cell-autonomous maintenance of fetal hematopoietic stem cells.

Liu F, Lee JY, Wei H, Tanabe O, Engel JD, Morrison SJ, Guan JL.

Blood. 2010 Dec 2;116(23):4806-14. doi: 10.1182/blood-2010-06-288589. Epub 2010 Aug 17.

33.

The TR2 and TR4 orphan nuclear receptors repress Gata1 transcription.

Tanabe O, Shen Y, Liu Q, Campbell AD, Kuroha T, Yamamoto M, Engel JD.

Genes Dev. 2007 Nov 1;21(21):2832-44.

34.

Linear distance from the locus control region determines epsilon-globin transcriptional activity.

Shimotsuma M, Matsuzaki H, Tanabe O, Campbell AD, Engel JD, Fukamizu A, Tanimoto K.

Mol Cell Biol. 2007 Aug;27(16):5664-72. Epub 2007 Jun 4.

35.

Embryonic and fetal beta-globin gene repression by the orphan nuclear receptors, TR2 and TR4.

Tanabe O, McPhee D, Kobayashi S, Shen Y, Brandt W, Jiang X, Campbell AD, Chen YT, Chang Cs, Yamamoto M, Tanimoto K, Engel JD.

EMBO J. 2007 May 2;26(9):2295-306. Epub 2007 Apr 12.

36.

Transcriptional interference among the murine beta-like globin genes.

Hu X, Eszterhas S, Pallazzi N, Bouhassira EE, Fields J, Tanabe O, Gerber SA, Bulger M, Engel JD, Groudine M, Fiering S.

Blood. 2007 Mar 1;109(5):2210-6. Epub 2006 Oct 31.

37.

Adult stage gamma-globin silencing is mediated by a promoter direct repeat element.

Omori A, Tanabe O, Engel JD, Fukamizu A, Tanimoto K.

Mol Cell Biol. 2005 May;25(9):3443-51.

38.

Expression of progastrin-releasing peptide and gastrin-releasing peptide receptor mRNA transcripts in tumor cells of patients with small cell lung cancer.

Uchida K, Kojima A, Morokawa N, Tanabe O, Anzai C, Kawakami M, Eto Y, Yoshimura K.

J Cancer Res Clin Oncol. 2002 Dec;128(12):633-40. Epub 2002 Nov 13.

PMID:
12474049
39.

[Status of life science research at Northwestern University--Studies on gene expression of beta-globin].

Tanabe O.

Tanpakushitsu Kakusan Koso. 2002 Aug;47(10):1344-9. Japanese. No abstract available.

PMID:
12184075
40.

An embryonic/fetal beta-type globin gene repressor contains a nuclear receptor TR2/TR4 heterodimer.

Tanabe O, Katsuoka F, Campbell AD, Song W, Yamamoto M, Tanimoto K, Engel JD.

EMBO J. 2002 Jul 1;21(13):3434-42.

41.

Fission yeast homologues of the B' subunit of protein phosphatase 2A: multiple roles in mitotic cell division and functional interaction with calcineurin.

Tanabe O, Hirata D, Usui H, Nishito Y, Miyakawa T, Igarashi K, Takeda M.

Genes Cells. 2001 May;6(5):455-73.

42.

Detection of measles virus genome in bronchoalveolar lavage cells in a patient with measles pneumonia.

Shimizu A, Tanabe O, Anzai C, Uchida K, Tada H, Yoshimura K.

Eur Respir J. 2000 Mar;15(3):619-22.

44.
45.

Direct metal analyses of Mn2+-dependent and -independent protein phosphatase 2A from human erythrocytes detect zinc and iron only in the Mn2+-independent one.

Nishito Y, Usui H, Shinzawa-Itoh K, Inoue R, Tanabe O, Nagase T, Murakami T, Takeda M.

FEBS Lett. 1999 Mar 19;447(1):29-33.

46.

Activation of NF-kappaB in Mycobacterium tuberculosis- induced interleukin-2 receptor expression in mononuclear phagocytes.

Tchou-Wong KM, Tanabe O, Chi C, Yie TA, Rom WN.

Am J Respir Crit Care Med. 1999 Apr;159(4 Pt 1):1323-9.

PMID:
10194184
47.

[Clinical features of the new influenza virus infection].

Tanabe O.

Ryoikibetsu Shokogun Shirizu. 1999;(23 Pt 1):77-9. Review. Japanese. No abstract available.

PMID:
10088342
48.

Negative association between asthma and variants of CC16(CC10) on chromosome 11q13 in British and Japanese populations.

Gao PS, Mao XQ, Kawai M, Enomoto T, Sasaki S, Tanabe O, Yoshimura K, Shaldon SR, Dake Y, Kitano H, Coull P, Shirakawa T, Hopkin JM.

Hum Genet. 1998 Jul;103(1):57-9.

PMID:
9737777
49.
50.

[Protein phosphatase 2A in the control of cell function].

Tanabe O.

Tanpakushitsu Kakusan Koso. 1998 Jun;43(8 Suppl):1013-20. Review. Japanese. No abstract available.

PMID:
9655958

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