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Isolation of highly pathogenic H5N6 avian influenza virus in Southern Vietnam with genetic similarity to those infecting humans in China.

Tsunekuni R, Sudo K, Nguyen PT, Luu BD, Phuong TD, Tan TM, Nguyen T, Mine J, Nakayama M, Tanikawa T, Sharshov K, Takemae N, Saito T.

Transbound Emerg Dis. 2019 Jul 15. doi: 10.1111/tbed.13294. [Epub ahead of print]


Combined GLP-1, Oxyntomodulin, and Peptide YY Improves Body Weight and Glycemia in Obesity and Prediabetes/Type 2 Diabetes: A Randomized, Single-Blinded, Placebo-Controlled Study.

Behary P, Tharakan G, Alexiadou K, Johnson N, Wewer Albrechtsen NJ, Kenkre J, Cuenco J, Hope D, Anyiam O, Choudhury S, Alessimii H, Poddar A, Minnion J, Doyle C, Frost G, Le Roux C, Purkayastha S, Moorthy K, Dhillo W, Holst JJ, Ahmed AR, Prevost AT, Bloom SR, Tan TM.

Diabetes Care. 2019 Aug;42(8):1446-1453. doi: 10.2337/dc19-0449. Epub 2019 Jun 8.


Adjunctive liraglutide treatment in patients with persistent or recurrent type 2 diabetes after metabolic surgery (GRAVITAS): a randomised, double-blind, placebo-controlled trial.

Miras AD, Pérez-Pevida B, Aldhwayan M, Kamocka A, McGlone ER, Al-Najim W, Chahal H, Batterham RL, McGowan B, Khan O, Greener V, Ahmed AR, Petrie A, Scholtz S, Bloom SR, Tan TM.

Lancet Diabetes Endocrinol. 2019 Jul;7(7):549-559. doi: 10.1016/S2213-8587(19)30157-3. Epub 2019 Jun 4.


No Guts, No Loss: Toward the Ideal Treatment for Obesity in the Twenty-First Century.

Hope DCD, Tan TMM, Bloom SR.

Front Endocrinol (Lausanne). 2018 Aug 15;9:442. doi: 10.3389/fendo.2018.00442. eCollection 2018. Review.


Of Mice Not Men? Actions of Interleukin-6 on Glucose Tolerance.

McGlone ER, Tan TM.

Cell Metab. 2018 Jun 5;27(6):1157-1158. doi: 10.1016/j.cmet.2018.05.013.


Beyond Weight Loss: Establishing a Postbariatric Surgery Patient Support Group-What Do Patients Want?

Hameed S, Salem V, Tan TM, Collins A, Shah K, Scholtz S, Ahmed AR, Chahal H.

J Obes. 2018 Feb 14;2018:8419120. doi: 10.1155/2018/8419120. eCollection 2018.


Does spending on refugees make a difference? A cross-sectional study of the association between refugee program spending and health outcomes in 70 sites in 17 countries.

Tan TM, Spiegel P, Haskew C, Greenough PG.

Confl Health. 2016 Dec 7;10:28. doi: 10.1186/s13031-016-0095-4. eCollection 2016.


RAMP2 Influences Glucagon Receptor Pharmacology via Trafficking and Signaling.

Cegla J, Jones BJ, Gardiner JV, Hodson DJ, Marjot T, McGlone ER, Tan TM, Bloom SR.

Endocrinology. 2017 Aug 1;158(8):2680-2693. doi: 10.1210/en.2016-1755.


The preanalytical stability of glucagon as measured by liquid chromatography tandem mass spectrometry and two commercially available immunoassays.

Cegla J, Jones BJ, Howard J, Kay R, Creaser CS, Bloom SR, Tan TM.

Ann Clin Biochem. 2017 Mar;54(2):293-296. doi: 10.1177/0004563216675648. Epub 2016 Nov 2.


Clinical roles in clinical biochemistry: a national survey of practice in the UK.

Choudhury SM, Williams EL, Barnes SC, Alaghband-Zadeh J, Tan TM, Cegla J.

Ann Clin Biochem. 2017 May;54(3):370-377. doi: 10.1177/0004563216664368. Epub 2016 Sep 1.


Peptide receptor radionuclide therapy for metastatic paragangliomas.

Pinato DJ, Black JR, Ramaswami R, Tan TM, Adjogatse D, Sharma R.

Med Oncol. 2016 May;33(5):47. doi: 10.1007/s12032-016-0737-9. Epub 2016 Apr 8.


Gastrointestinal hormones and their role in obesity.

Choudhury SM, Tan TM, Bloom SR.

Curr Opin Endocrinol Diabetes Obes. 2016 Feb;23(1):18-22. doi: 10.1097/MED.0000000000000216. Review.


Up-regulation of microRNA-210 inhibits proliferation of hepatocellular carcinoma cells by targeting YES1.

Tan W, Lim SG, Tan TM.

World J Gastroenterol. 2015 Dec 14;21(46):13030-41. doi: 10.3748/wjg.v21.i46.13030.


Glucagon increases energy expenditure independently of brown adipose tissue activation in humans.

Salem V, Izzi-Engbeaya C, Coello C, Thomas DB, Chambers ES, Comninos AN, Buckley A, Win Z, Al-Nahhas A, Rabiner EA, Gunn RN, Budge H, Symonds ME, Bloom SR, Tan TM, Dhillo WS.

Diabetes Obes Metab. 2016 Jan;18(1):72-81. doi: 10.1111/dom.12585. Epub 2015 Nov 20.


Suicide screening tools and their association with near-term adverse events in the ED.

Chang BP, Tan TM.

Am J Emerg Med. 2015 Nov;33(11):1680-3. doi: 10.1016/j.ajem.2015.08.013. Epub 2015 Aug 10.


A Malaysia 97 monovalent foot-and-mouth disease vaccine (>6PD50/dose) protects pigs against challenge with a variant FMDV A SEA-97 lineage virus, 4 and 7 days post vaccination.

Nagendrakumar SB, Hong NT, Geoffrey FT, Jacqueline MM, Andrew D, Michelle G, Van Phuc K, Ngon QV, Phuong le TT, Phuc NN, Hanh TX, Van Hung V, Quynhanh le T, Tan TM, Long NT, Wilna V.

Vaccine. 2015 Aug 26;33(36):4513-9. doi: 10.1016/j.vaccine.2015.07.014. Epub 2015 Jul 17.


Obesity: Lifestyle management, bariatric surgery, drugs, and the therapeutic exploitation of gut hormones.

Behary P, Cegla J, Tan TM, Bloom SR.

Postgrad Med. 2015 Jun;127(5):494-502. doi: 10.1080/00325481.2015.1048181. Review.


Family structure and sexual and reproductive health outcomes among adolescents in rural Sierra Leone.

Stark L, Tan TM, Muldoon KA, King D, Lamin DFM, Lilley S, Wessells MG.

Glob Public Health. 2016 Mar;11(3):309-321. doi: 10.1080/17441692.2015.1031155. Epub 2015 Apr 16.


Can Bayliss and Starling gut hormones cure a worldwide pandemic?

Scott RV, Tan TM, Bloom SR.

J Physiol. 2014 Dec 1;592(23):5153-67. doi: 10.1113/jphysiol.2014.272955. Epub 2014 Sep 12.


Combination of peptide YY3-36 with GLP-1(7-36) amide causes an increase in first-phase insulin secretion after IV glucose.

Tan TM, Salem V, Troke RC, Alsafi A, Field BC, De Silva A, Misra S, Baynes KC, Donaldson M, Minnion J, Ghatei MA, Godsland IF, Bloom SR.

J Clin Endocrinol Metab. 2014 Nov;99(11):E2317-24. doi: 10.1210/jc.2014-2143. Epub 2014 Aug 21.


Coinfusion of low-dose GLP-1 and glucagon in man results in a reduction in food intake.

Cegla J, Troke RC, Jones B, Tharakan G, Kenkre J, McCullough KA, Lim CT, Parvizi N, Hussein M, Chambers ES, Minnion J, Cuenco J, Ghatei MA, Meeran K, Tan TM, Bloom SR.

Diabetes. 2014 Nov;63(11):3711-20. doi: 10.2337/db14-0242. Epub 2014 Jun 17.


miR-106b-25/miR-17-92 clusters: polycistrons with oncogenic roles in hepatocellular carcinoma.

Tan W, Li Y, Lim SG, Tan TM.

World J Gastroenterol. 2014 May 28;20(20):5962-72. doi: 10.3748/wjg.v20.i20.5962. Review.


The biochemistry and cell biology of aging: metabolic regulation through mitochondrial signaling.

Long YC, Tan TM, Takao I, Tang BL.

Am J Physiol Endocrinol Metab. 2014 Mar;306(6):E581-91. doi: 10.1152/ajpendo.00665.2013. Epub 2014 Jan 22. Review.


The future role of gut hormones in the treatment of obesity.

Troke RC, Tan TM, Bloom SR.

Ther Adv Chronic Dis. 2014 Jan;5(1):4-14. doi: 10.1177/2040622313506730. Review.


An expression signature of the angiogenic response in gastrointestinal neuroendocrine tumours: correlation with tumour phenotype and survival outcomes.

Pinato DJ, Tan TM, Toussi ST, Ramachandran R, Martin N, Meeran K, Ngo N, Dina R, Sharma R.

Br J Cancer. 2014 Jan 7;110(1):115-22. doi: 10.1038/bjc.2013.682. Epub 2013 Nov 14.


Immunohistochemical markers of the hypoxic response can identify malignancy in phaeochromocytomas and paragangliomas and optimize the detection of tumours with VHL germline mutations.

Pinato DJ, Ramachandran R, Toussi ST, Vergine M, Ngo N, Sharma R, Lloyd T, Meeran K, Palazzo F, Martin N, Khoo B, Dina R, Tan TM.

Br J Cancer. 2013 Feb 5;108(2):429-37. doi: 10.1038/bjc.2012.538. Epub 2012 Dec 20.


Coadministration of glucagon-like peptide-1 during glucagon infusion in humans results in increased energy expenditure and amelioration of hyperglycemia.

Tan TM, Field BC, McCullough KA, Troke RC, Chambers ES, Salem V, Gonzalez Maffe J, Baynes KC, De Silva A, Viardot A, Alsafi A, Frost GS, Ghatei MA, Bloom SR.

Diabetes. 2013 Apr;62(4):1131-8. doi: 10.2337/db12-0797. Epub 2012 Dec 17.


The role of the gut/brain axis in modulating food intake.

Sam AH, Troke RC, Tan TM, Bewick GA.

Neuropharmacology. 2012 Jul;63(1):46-56. doi: 10.1016/j.neuropharm.2011.10.008. Epub 2011 Oct 21. Review.


A role for metalloendopeptidases in the breakdown of the gut hormone, PYY 3-36.

Addison ML, Minnion JS, Shillito JC, Suzuki K, Tan TM, Field BC, Germain-Zito N, Becker-Pauly C, Ghatei MA, Bloom SR, Murphy KG.

Endocrinology. 2011 Dec;152(12):4630-40. doi: 10.1210/en.2011-1195. Epub 2011 Sep 27.


A novel MLL5 isoform that is essential to activate E6 and E7 transcription in HPV16/18-associated cervical cancers.

Yew CW, Lee P, Chan WK, Lim VK, Tay SK, Tan TM, Deng LW.

Cancer Res. 2011 Nov 1;71(21):6696-707. doi: 10.1158/0008-5472.CAN-11-1271. Epub 2011 Sep 9.


Pharmacokinetics, adverse effects and tolerability of a novel analogue of human pancreatic polypeptide, PP 1420.

Tan TM, Field BC, Minnion JS, Cuenco-Shillito J, Chambers ES, Zac-Varghese S, Brindley CJ, Mt-Isa S, Fiorentino F, Ashby D, Ward I, Ghatei MA, Bloom SR.

Br J Clin Pharmacol. 2012 Feb;73(2):232-9. doi: 10.1111/j.1365-2125.2011.04082.x.


A global transcriptomic view of the multifaceted role of glutathione peroxidase-1 in cerebral ischemic-reperfusion injury.

Chen MJ, Wong CH, Peng ZF, Manikandan J, Melendez AJ, Tan TM, Crack PJ, Cheung NS.

Free Radic Biol Med. 2011 Mar 15;50(6):736-48. doi: 10.1016/j.freeradbiomed.2010.12.025. Epub 2010 Dec 28.


NRAMP1 and hGPX1 gene polymorphism and response to bacillus Calmette-Guérin therapy for bladder cancer.

Chiong E, Kesavan A, Mahendran R, Chan YH, Sng JH, Lim YK, Kamaraj R, Tan TM, Esuvaranathan K.

Eur Urol. 2011 Mar;59(3):430-7. doi: 10.1016/j.eururo.2010.11.031. Epub 2010 Dec 1.


Gene profiling reveals hydrogen sulphide recruits death signaling via the N-methyl-D-aspartate receptor identifying commonalities with excitotoxicity.

Chen MJ, Peng ZF, Manikandan J, Melendez AJ, Tan GS, Chung CM, Li QT, Tan TM, Deng LW, Whiteman M, Beart PM, Moore PK, Cheung NS.

J Cell Physiol. 2011 May;226(5):1308-22. doi: 10.1002/jcp.22459.


Gut-brain cross-talk in appetite regulation.

Cegla J, Tan TM, Bloom SR.

Curr Opin Clin Nutr Metab Care. 2010 Sep;13(5):588-93. doi: 10.1097/MCO.0b013e32833b64a3. Review.


Role of the miR-106b-25 microRNA cluster in hepatocellular carcinoma.

Li Y, Tan W, Neo TW, Aung MO, Wasser S, Lim SG, Tan TM.

Cancer Sci. 2009 Jul;100(7):1234-42. doi: 10.1111/j.1349-7006.2009.01164.x. Epub 2009 Apr 15.


A legacy of tinnitus: multiple head and neck paragangliomas.

Tan TM, Hatfield EC, Thakker RV, Maher ER, Meeran K, Martin NM, Turner JJ.

Rare Tumors. 2009 Dec 28;1(2):e29. doi: 10.4081/rt.2009.e29.


Automated device that complies with current guidelines for office blood pressure measurement: design and pilot application study of the Microlife WatchBP Office device.

Stergiou GS, Lin CW, Lin CM, Chang SL, Protogerou AD, Tzamouranis D, Nasothimiou E, Tan TM.

Blood Press Monit. 2008 Aug;13(4):231-5. doi: 10.1097/MBP.0b013e3283057a84.


MELAS syndrome, diabetes and thyroid disease: the role of mitochondrial oxidative stress.

Tan TM, Caputo C, Medici F, Pambakian AL, Dornhorst A, Meeran K, Williams GR, Khoo B.

Clin Endocrinol (Oxf). 2009 Feb;70(2):340-1. doi: 10.1111/j.1365-2265.2008.03341.x. Epub 2008 Jul 7. No abstract available.


The obesity epidemic: pharmacological challenges.

Bloom SR, Kuhajda FP, Laher I, Pi-Sunyer X, Ronnett GV, Tan TM, Weigle DS.

Mol Interv. 2008 Apr;8(2):82-98. doi: 10.1124/mi.8.2.6. Review.


The pursuit of beauty.

Druce M, Goldstone AP, Tan TM, Meeran K.

Lancet. 2008 Feb 16;371(9612):596. doi: 10.1016/S0140-6736(08)60272-X. No abstract available.


Induction of human sulfotransferase 1A3 (SULT1A3) by glucocorticoids.

Bian HS, Ngo SY, Tan W, Wong CH, Boelsterli UA, Tan TM.

Life Sci. 2007 Dec 14;81(25-26):1659-67. Epub 2007 Oct 9.


Pituitary macroadenomas: are combination antiplatelet and anticoagulant therapy contraindicated? A case report.

Tan TM, Caputo C, Mehta A, Hatfield EC, Martin NM, Meeran K.

J Med Case Rep. 2007 Aug 30;1:74.


Inhibition of enterovirus 71 in virus-infected mice by RNA interference.

Tan EL, Tan TM, Tak Kwong Chow V, Poh CL.

Mol Ther. 2007 Nov;15(11):1931-8. Epub 2007 Aug 21.


Molecular and functional characterization of drug-metabolizing enzymes and transporter expression in the novel spontaneously immortalized human hepatocyte line HC-04.

Lim PL, Tan W, Latchoumycandane C, Mok WC, Khoo YM, Lee HS, Sattabongkot J, Beerheide W, Lim SG, Tan TM, Boelsterli UA.

Toxicol In Vitro. 2007 Dec;21(8):1390-401. Epub 2007 May 17.


Control of quorum sensing by a Burkholderia pseudomallei multidrug efflux pump.

Chan YY, Bian HS, Tan TM, Mattmann ME, Geske GD, Igarashi J, Hatano T, Suga H, Blackwell HE, Chua KL.

J Bacteriol. 2007 Jun;189(11):4320-4. Epub 2007 Mar 23.


A tool for reliable self-home blood pressure monitoring designed according to the European Society of Hypertension recommendations: the Microlife WatchBP Home monitor.

Stergiou GS, Jaenecke B, Giovas PP, Chang A, Chung-Yueh Y, Tan TM.

Blood Press Monit. 2007 Apr;12(2):127-31. Review.


Traceless solid-phase synthesis and biological evaluation of purine analogs as inhibitors of multidrug resistance protein 4.

Tan TM, Yang F, Fu H, Raghavendra MS, Lam Y.

J Comb Chem. 2007 Mar-Apr;9(2):210-8.


Enhanced potency and efficacy of 29-mer shRNAs in inhibition of Enterovirus 71.

Tan EL, Tan TM, Chow VT, Poh CL.

Antiviral Res. 2007 Apr;74(1):9-15. Epub 2007 Jan 31.


Vitamin D status in patients with osteopenia or osteoporosis--an audit of an endocrine clinic.

Kocjan T, Tan TM, Conway GS, Prelevic G.

Int J Vitam Nutr Res. 2006 Sep;76(5):307-13.


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