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MAP4K Family Kinases and DUSP Family Phosphatases in T-Cell Signaling and Systemic Lupus Erythematosus.

Chuang HC, Tan TH.

Cells. 2019 Nov 13;8(11). pii: E1433. doi: 10.3390/cells8111433. Review.


The Impact of Pre-operative Nutritional Status on Outcomes Following Congenital Heart Surgery.

Lim CYS, Lim JKB, Moorakonda RB, Ong C, Mok YH, Allen JC, Wong JJ, Tan TH, Lee JH.

Front Pediatr. 2019 Oct 23;7:429. doi: 10.3389/fped.2019.00429. eCollection 2019.


DUSP22 suppresses prostate cancer proliferation by targeting the EGFR-AR axis.

Lin HP, Ho HM, Chang CW, Yeh SD, Su YW, Tan TH, Lin WJ.

FASEB J. 2019 Dec;33(12):14653-14667. doi: 10.1096/fj.201802558RR. Epub 2019 Nov 5.


MAP4K3/GLK in autoimmune disease, cancer and aging.

Chuang HC, Tan TH.

J Biomed Sci. 2019 Oct 22;26(1):82. doi: 10.1186/s12929-019-0570-5. Review.


Intelligent Lecturer Tracking and Capturing System Based on Face Detection and Wireless Sensing Technology.

Tan TH, Kuo TY, Liu H.

Sensors (Basel). 2019 Sep 27;19(19). pii: E4193. doi: 10.3390/s19194193.


MAP4K3/GLK Promotes Lung Cancer Metastasis by Phosphorylating and Activating IQGAP1.

Chuang HC, Chang CC, Teng CF, Hsueh CH, Chiu LL, Hsu PM, Lee MC, Hsu CP, Chen YR, Liu YC, Lyu PC, Tan TH.

Cancer Res. 2019 Oct 1;79(19):4978-4993. doi: 10.1158/0008-5472.CAN-19-1402. Epub 2019 Aug 20.


Primary myelofibrosis: spectrum of imaging features and disease-related complications.

Oon SF, Singh D, Tan TH, Lee A, Noe G, Burbury K, Paiva J.

Insights Imaging. 2019 Aug 7;10(1):71. doi: 10.1186/s13244-019-0758-y. Review.


AhR-ROR-γt complex is a therapeutic target for MAP4K3/GLKhighIL-17Ahigh subpopulation of systemic lupus erythematosus.

Chuang HC, Chen YM, Chen MH, Hung WT, Yang HY, Tseng YH, Tan TH.

FASEB J. 2019 Oct;33(10):11469-11480. doi: 10.1096/fj.201900105RR. Epub 2019 Aug 1.


Quality of reporting on thoracic radiotherapy technique in prospective lung cancer trials: A systematic review.

Soon YY, Chen D, Tan TH, Tey JCS.

Medicine (Baltimore). 2019 Jun;98(26):e16124. doi: 10.1097/MD.0000000000016124.


Application of 18F-FDG PET-CT in the management of pulmonary nodule and mass - a pictorial review.

Wong TH, Tan TH, George UR, Kow KS, Liam CK.

Med J Malaysia. 2019 Jun;74(3):250-256.


Comparison of Risk for End-Stage Renal Disease Between Physicians and the General Population: A Nationwide Population-Based Cohort Study.

Yen CK, Tan TH, Feng IJ, Ho CH, Hsu CC, Lin HJ, Wang JJ, Huang CC.

Int J Environ Res Public Health. 2019 Jun 22;16(12). pii: E2211. doi: 10.3390/ijerph16122211.


Enzalutamide with Standard First-Line Therapy in Metastatic Prostate Cancer.

Davis ID, Martin AJ, Stockler MR, Begbie S, Chi KN, Chowdhury S, Coskinas X, Frydenberg M, Hague WE, Horvath LG, Joshua AM, Lawrence NJ, Marx G, McCaffrey J, McDermott R, McJannett M, North SA, Parnis F, Parulekar W, Pook DW, Reaume MN, Sandhu SK, Tan A, Tan TH, Thomson A, Tu E, Vera-Badillo F, Williams SG, Yip S, Zhang AY, Zielinski RR, Sweeney CJ; ENZAMET Trial Investigators and the Australian and New Zealand Urogenital and Prostate Cancer Trials Group.

N Engl J Med. 2019 Jul 11;381(2):121-131. doi: 10.1056/NEJMoa1903835. Epub 2019 Jun 2.


Regulation of Dual-Specificity Phosphatase (DUSP) Ubiquitination and Protein Stability.

Chen HF, Chuang HC, Tan TH.

Int J Mol Sci. 2019 May 30;20(11). pii: E2668. doi: 10.3390/ijms20112668. Review.


Automated image analysis of NSCLC biopsies to predict response to anti-PD-L1 therapy.

Althammer S, Tan TH, Spitzmüller A, Rognoni L, Wiestler T, Herz T, Widmaier M, Rebelatto MC, Kaplon H, Damotte D, Alifano M, Hammond SA, Dieu-Nosjean MC, Ranade K, Schmidt G, Higgs BW, Steele KE.

J Immunother Cancer. 2019 May 6;7(1):121. doi: 10.1186/s40425-019-0589-x.


MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo.

Fiedler LR, Chapman K, Xie M, Maifoshie E, Jenkins M, Golforoush PA, Bellahcene M, Noseda M, Faust D, Jarvis A, Newton G, Paiva MA, Harada M, Stuckey DJ, Song W, Habib J, Narasimham P, Aqil R, Sanmugalingam D, Yan R, Pavanello L, Sano M, Wang SC, Sampson RD, Kanayaganam S, Taffet GE, Michael LH, Entman ML, Tan TH, Harding SE, Low CMR, Tralau-Stewart C, Perrior T, Schneider MD.

Cell Stem Cell. 2019 Apr 4;24(4):579-591.e12. doi: 10.1016/j.stem.2019.01.013. Epub 2019 Mar 7.


ECG Noise Cancellation Based on Grey Spectral Noise Estimation.

Liu SH, Hsieh CH, Chen W, Tan TH.

Sensors (Basel). 2019 Feb 15;19(4). pii: E798. doi: 10.3390/s19040798.


Malignant mesothelioma of the tunica vaginalis: a atypical presentation of a rare scrotal tumour.

Harris MC, Logan C, Chetwood A, Cohen P, Titus J, Tan TH, Higgs B, Brook NR.

ANZ J Surg. 2019 Feb 1. doi: 10.1111/ans.14964. [Epub ahead of print] No abstract available.


Comparing disease-specific and generic quality of life measures in patients with schizophrenia.

Seow LSE, Tan THG, Abdin E, Chong SA, Subramaniam M.

Psychiatry Res. 2019 Mar;273:387-393. doi: 10.1016/j.psychres.2019.01.034. Epub 2019 Jan 11.


Medical management of metastatic prostate cancer.

Body A, Pranavan G, Tan TH, Slobodian P.

Aust Prescr. 2018 Oct;41(5):154-159. doi: 10.18773/austprescr.2018.046. Epub 2018 Oct 2. Review. No abstract available.


Using the Pulse Contour Method to Measure the Changes in Stroke Volume during a Passive Leg Raising Test.

Su CH, Liu SH, Tan TH, Lo CH.

Sensors (Basel). 2018 Oct 12;18(10). pii: E3420. doi: 10.3390/s18103420.


Identification and Characterization of Genes in the Curcuminoid Pathway of Curcuma zedoaria Roscoe.

Lan TTP, Huy ND, Luong NN, Nghi NV, Tan TH, Quan LV, Loc NH.

Curr Pharm Biotechnol. 2018;19(10):839-846. doi: 10.2174/1389201019666181008112244.


PP4 deficiency leads to DNA replication stress that impairs immunoglobulin class switch efficiency.

Chen MY, Hsu WC, Hsu SC, Yang YS, Chuang TH, Lin WJ, Tan TH, Su YW.

Cell Death Differ. 2019 Jul;26(7):1221-1234. doi: 10.1038/s41418-018-0199-z. Epub 2018 Sep 20.


GLK-IKKβ signaling induces dimerization and translocation of the AhR-RORγt complex in IL-17A induction and autoimmune disease.

Chuang HC, Tsai CY, Hsueh CH, Tan TH.

Sci Adv. 2018 Sep 12;4(9):eaat5401. doi: 10.1126/sciadv.aat5401. eCollection 2018 Sep.


RBM4a-SRSF3-MAP4K4 Splicing Cascade Constitutes a Molecular Mechanism for Regulating Brown Adipogenesis.

Peng HY, Liang YC, Tan TH, Chuang HC, Lin YJ, Lin JC.

Int J Mol Sci. 2018 Sep 6;19(9). pii: E2646. doi: 10.3390/ijms19092646.


Habitat complexity affects benthic harmful dinoflagellate assemblages in the fringing reef of Rawa Island, Malaysia.

Yong HL, Mustapa NI, Lee LK, Lim ZF, Tan TH, Usup G, Gu H, Litaker RW, Tester PA, Lim PT, Leaw CP.

Harmful Algae. 2018 Sep;78:56-68. doi: 10.1016/j.hal.2018.07.009. Epub 2018 Aug 10.


DUSP6 mediates T cell receptor-engaged glycolysis and restrains TFH cell differentiation.

Hsu WC, Chen MY, Hsu SC, Huang LR, Kao CY, Cheng WH, Pan CH, Wu MS, Yu GY, Hung MS, Leu CM, Tan TH, Su YW.

Proc Natl Acad Sci U S A. 2018 Aug 21;115(34):E8027-E8036. doi: 10.1073/pnas.1800076115. Epub 2018 Aug 7.


Unobtrusive Activity Recognition of Elderly People Living Alone Using Anonymous Binary Sensors and DCNN.

Gochoo M, Tan TH, Liu SH, Jean FR, Alnajjar FS, Huang SC.

IEEE J Biomed Health Inform. 2019 Mar;23(2):693-702. doi: 10.1109/JBHI.2018.2833618. Epub 2018 May 7.


Induction of DUSP14 ubiquitination by PRMT5-mediated arginine methylation.

Yang CY, Chiu LL, Chang CC, Chuang HC, Tan TH.

FASEB J. 2018 Jun 19:fj201800244RR. doi: 10.1096/fj.201800244RR. [Epub ahead of print]


Nutritional practices and adequacy in children supported on extracorporeal membrane oxygenation.

Ong C, Mok YH, Tan ZH, Lim CYS, Ang B, Tan TH, Loh YJ, Chan YH, Lee JH.

Clin Nutr ESPEN. 2018 Aug;26:21-26. doi: 10.1016/j.clnesp.2018.05.005. Epub 2018 May 30.


Self-organized stress patterns drive state transitions in actin cortices.

Tan TH, Malik-Garbi M, Abu-Shah E, Li J, Sharma A, MacKintosh FC, Keren K, Schmidt CF, Fakhri N.

Sci Adv. 2018 Jun 6;4(6):eaar2847. doi: 10.1126/sciadv.aar2847. eCollection 2018 Jun.


Quality of radiotherapy reporting in randomized controlled trials of prostate cancer.

Soon YY, Chen D, Tan TH, Tey J.

Radiat Oncol. 2018 Jun 7;13(1):108. doi: 10.1186/s13014-018-1053-7.


Impact of 68Ga-DOTA-Peptide PET/CT on the Management of Gastrointestinal Neuroendocrine Tumour (GI-NET): Malaysian National Referral Centre Experience.

Tan TH, Boey CY, Lee BN.

Nucl Med Mol Imaging. 2018 Apr;52(2):119-124. doi: 10.1007/s13139-017-0496-3. Epub 2017 Dec 8.


Quality of head and neck radiotherapy reporting in randomized controlled trials.

Tseng M, Tan TH, Zheng H, Soon YY, Tey J.

Head Neck. 2018 Aug;40(8):1854-1860. doi: 10.1002/hed.25133. Epub 2018 Mar 25. Review.


Induction chemotherapy for locally advanced nasopharyngeal carcinoma treated with concurrent chemoradiation: A systematic review and meta-analysis.

Tan TH, Soon YY, Cheo T, Ho F, Wong LC, Tey J, Tham IWK.

Radiother Oncol. 2018 Oct;129(1):10-17. doi: 10.1016/j.radonc.2018.02.027. Epub 2018 Mar 16.


Measuring multiple parameters of CD8+ tumor-infiltrating lymphocytes in human cancers by image analysis.

Steele KE, Tan TH, Korn R, Dacosta K, Brown C, Kuziora M, Zimmermann J, Laffin B, Widmaier M, Rognoni L, Cardenes R, Schneider K, Boutrin A, Martin P, Zha J, Wiestler T.

J Immunother Cancer. 2018 Mar 6;6(1):20. doi: 10.1186/s40425-018-0326-x.


Novel use of a balloon dilatation catheter to enable mechanical lithotripsy of difficult common bile duct stones after initial failed attempt: A case report.

Loh WL, Tung JYM, Tan THY, Tan LT, Tan S, Ngoi SS.

Int J Surg Case Rep. 2018;43:9-12. doi: 10.1016/j.ijscr.2018.01.005. Epub 2018 Jan 28.


The Impact of Time to Rate Control of Junctional Ectopic Tachycardia After Congenital Heart Surgery.

Lim JKB, Mok YH, Loh YJ, Tan TH, Lee JH.

World J Pediatr Congenit Heart Surg. 2017 Nov;8(6):685-690. doi: 10.1177/2150135117732544.


RBM4-SRSF3-MAP4K4 splicing cascade modulates the metastatic signature of colorectal cancer cell.

Lin JC, Lee YC, Tan TH, Liang YC, Chuang HC, Fann YC, Johnson KR, Lin YJ.

Biochim Biophys Acta Mol Cell Res. 2018 Feb;1865(2):259-272. doi: 10.1016/j.bbamcr.2017.11.005. Epub 2017 Nov 11.


Deficiency in VHR/DUSP3, a suppressor of focal adhesion kinase, reveals its role in regulating cell adhesion and migration.

Chen YR, Chou HC, Yang CH, Chen HY, Liu YW, Lin TY, Yeh CL, Chao WT, Tsou HH, Chuang HC, Tan TH.

Oncogene. 2017 Nov 23;36(47):6509-6517. doi: 10.1038/onc.2017.255. Epub 2017 Jul 31.


18F-FDG Uptake in Benign Fibrous Histiocytoma of Adrenal Gland: A Potential Pitfall.

Tan TH, Lai CNB.

Clin Nucl Med. 2017 Aug;42(8):622-623. doi: 10.1097/RLU.0000000000001730.


Stereotactic ablative body radiotherapy for inoperable primary kidney cancer: a prospective clinical trial.

Siva S, Pham D, Kron T, Bressel M, Lam J, Tan TH, Chesson B, Shaw M, Chander S, Gill S, Brook NR, Lawrentschuk N, Murphy DG, Foroudi F.

BJU Int. 2017 Nov;120(5):623-630. doi: 10.1111/bju.13811. Epub 2017 Mar 10.


Ubiquitous Emergency Medical Service System Based on Wireless Biosensors, Traffic Information, and Wireless Communication Technologies: Development and Evaluation.

Tan TH, Gochoo M, Chen YF, Hu JJ, Chiang JY, Chang CS, Lee MH, Hsu YN, Hsu JC.

Sensors (Basel). 2017 Jan 21;17(1). pii: E202. doi: 10.3390/s17010202.


New scenario for speciation in the benthic dinoflagellate genus Coolia (Dinophyceae).

Leaw CP, Tan TH, Lim HC, Teng ST, Yong HL, Smith KF, Rhodes L, Wolf M, Holland WC, Vandersea MW, Litaker RW, Tester PA, Gu H, Usup G, Lim PT.

Harmful Algae. 2016 May;55:137-149. doi: 10.1016/j.hal.2016.02.010. Epub 2016 Mar 15.


MAP4K4 and IL-6+ Th17 cells play important roles in non-obese type 2 diabetes.

Chuang HC, Tan TH.

J Biomed Sci. 2017 Jan 7;24(1):4. doi: 10.1186/s12929-016-0307-7. Review.


Dual-specificity phosphatase 6 deficiency regulates gut microbiome and transcriptome response against diet-induced obesity in mice.

Ruan JW, Statt S, Huang CT, Tsai YT, Kuo CC, Chan HL, Liao YC, Tan TH, Kao CY.

Nat Microbiol. 2016 Nov 28;2:16220. doi: 10.1038/nmicrobiol.2016.220.


Feasibility study of toxicity outcomes using GEC-ESTRO contouring guidelines on CT based instead of MRI-based planning in locally advanced cervical cancer patients.

Koh V, Choo BA, Lee KM, Tan TH, Low JH, Ng SY, Ilancheran A, Shen L, Tang J.

Brachytherapy. 2017 Jan - Feb;16(1):126-132. doi: 10.1016/j.brachy.2016.09.009. Epub 2016 Nov 2.


Super-resolution imaging of fluorescently labeled, endogenous RNA Polymerase II in living cells with CRISPR/Cas9-mediated gene editing.

Cho WK, Jayanth N, Mullen S, Tan TH, Jung YJ, Cissé II.

Sci Rep. 2016 Oct 26;6:35949. doi: 10.1038/srep35949.


Clinical, demographic and laboratory characteristics of methotrexate-responsive eczema.

Chen KS, Tan TH, Yesudian PD.

J Eur Acad Dermatol Venereol. 2016 Nov;30(11):e158-e159. doi: 10.1111/jdv.13465. Epub 2015 Nov 11. No abstract available.


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