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A head-to-head evaluation of the diagnostic efficacy and costs of trio versus singleton exome sequencing analysis.

Tan TY, Lunke S, Chong B, Phelan D, Fanjul-Fernandez M, Marum JE, Kumar VS, Stark Z, Yeung A, Brown NJ, Stutterd C, Delatycki MB, Sadedin S, Martyn M, Goranitis I, Thorne N, Gaff CL, White SM.

Eur J Hum Genet. 2019 Jul 18. doi: 10.1038/s41431-019-0471-9. [Epub ahead of print]


Definition of Successful Infection Management and Guidelines for Reporting of Outcomes After Surgical Treatment of Periprosthetic Joint Infection: From the Workgroup of the Musculoskeletal Infection Society (MSIS).

Fillingham YA, Della Valle CJ, Suleiman LI, Springer BD, Gehrke T, Bini SA, Segreti J, Chen AF, Goswami K, Tan TL, Shohat N, Diaz-Ledezma C, Schwartz AJ, Parvizi J.

J Bone Joint Surg Am. 2019 Jul 17;101(14):e69. doi: 10.2106/JBJS.19.00062. No abstract available.


AhR-ROR-γt complex is a therapeutic target for MAP4K3/GLKhighIL-17Ahigh subpopulation of systemic lupus erythematosus.

Chuang HC, Chen YM, Chen MH, Hung WT, Yang HY, Tseng YH, Tan TH.

FASEB J. 2019 Jul 18:fj201900105RR. doi: 10.1096/fj.201900105RR. [Epub ahead of print]


Impact of an interstitial lung disease service in the diagnosis and management of interstitial lung disease in Singapore.

Chai GT, Tan TC, Lee YS, Kaw GJ, Chuah KL, Lim YJ, Abisheganaden JA, Thong BY.

Singapore Med J. 2019 Jul 11. doi: 10.11622/smedj.2019069. [Epub ahead of print]


Familial hypercholesterolemia with early coronary atherosclerotic heart disease: A case report.

Luo Y, Zheng M, Zhang Y, He S, Zhang L, Sun H, Liu X, Tan T, Zhu H, He J.

Exp Ther Med. 2019 Aug;18(2):981-986. doi: 10.3892/etm.2019.7653. Epub 2019 Jun 10.


Ascertaining the burden of invasive Salmonella disease in hospitalised febrile children aged under four years in Blantyre, Malawi.

Msefula CL, Olgemoeller F, Jambo N, Segula D, Van Tan T, Nyirenda TS, Nedi W, Kennedy N, Graham M, Henrion MYR, Baker S, Feasey N, Gordon M, Heyderman RS.

PLoS Negl Trop Dis. 2019 Jul 17;13(7):e0007539. doi: 10.1371/journal.pntd.0007539. [Epub ahead of print]


Clinical and Pathophysiologic Significance of MRI Identified Bone Marrow Lesions Associated with Knee Osteoarthritis.

Singh V, Oliashirazi A, Tan T, Fayyad A, Shahi A.

Arch Bone Jt Surg. 2019 May;7(3):211-219. Review.


Validation of an indirect immunofluorescence assay (IFA) for the detection of IgG antibodies against Coxiella burnetii in bovine serum.

Wood C, Muleme M, Tan T, Bosward K, Gibson J, Alawneh J, McGowan M, Barnes TS, Stenos J, Perkins N, Firestone SM, Tozer S.

Prev Vet Med. 2019 Aug 1;169:104698. doi: 10.1016/j.prevetmed.2019.104698. Epub 2019 May 23.


Compressive Deformation and Failure of Trabecular Structures in A Turtle Shell.

Ampaw E, Owoseni TA, Du F, Pinilla N, Obayemi J, Hu J, Nigay PM, Nzihou A, Uzonwanne V, Kana Z, Dewoolkar M, Tan T, Soboyejo W.

Acta Biomater. 2019 Jul 13. pii: S1742-7061(19)30503-3. doi: 10.1016/j.actbio.2019.07.023. [Epub ahead of print]


Isolation of highly pathogenic H5N6 avian influenza virus in Southern Vietnam with genetic similarity to those infecting humans in China.

Tsunekuni R, Sudo K, Nguyen PT, Luu BD, Phuong TD, Tan TM, Tung N, Mine J, Nakayama M, Tanikawa T, Sharshov K, Takemae N, Saito T.

Transbound Emerg Dis. 2019 Jul 15. doi: 10.1111/tbed.13294. [Epub ahead of print]


Dihydrotanshinone I inhibits the growth of osteosarcoma through the Wnt/β-catenin signaling pathway.

Tan T, Chen J, Hu Y, Wang N, Chen Y, Yu T, Lin D, Yang S, Luo J, Luo X.

Onco Targets Ther. 2019 Jul 2;12:5111-5122. doi: 10.2147/OTT.S204574. eCollection 2019.


Reevaluating Current Cutoffs for Acute Periprosthetic Joint Infection: Current Thresholds Are Insensitive.

Xu C, Tan TL, Kuo FC, Goswami K, Wang Q, Parvizi J.

J Arthroplasty. 2019 Jun 27. pii: S0883-5403(19)30639-4. doi: 10.1016/j.arth.2019.06.048. [Epub ahead of print]


[Correlation of quality of life with self-care efficacy and social support in patients with nasopharyngeal carcinoma after radiotherapy].

Tan T, Shen Y, Zhou X, Zhou B, Cheng M.

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2019 Jun 28;44(6):672-678. doi: 10.11817/j.issn.1672-7347.2019.06.010. Chinese.


Incidence and patterns of malignancies in a multi-ethnic cohort of rheumatoid arthritis patients.

Lim XR, Xiang W, Tan JWL, Koh LW, Lian TY, Leong KP, Koh ET; TTSH Rheumatoid Arthritis Study Group.

Int J Rheum Dis. 2019 Jul 11. doi: 10.1111/1756-185X.13655. [Epub ahead of print]


The mouse curly whiskers (cw) mutations are recessive alleles of hephaestin-like 1 (Hephl1).

Eragene S, Stewart JJ, Samuel-Constanzo JI, Tan T, Esgdaille NZ, Bigiarelli KJ, DaCosta VD, Jimenez H, King TR.

Mol Genet Metab Rep. 2019 Jun 20;20:100478. doi: 10.1016/j.ymgmr.2019.100478. eCollection 2019 Sep.


Association of the TP53 rs1042522 C>G polymorphism and hepatoblastoma risk in Chinese children.

Yang T, Wen Y, Li J, Yang J, Tan T, Pan J, Hu C, Zhang J, Xin Y, Li S, Xia H, He J, Zou Y.

J Cancer. 2019 Jun 9;10(15):3444-3449. doi: 10.7150/jca.33063. eCollection 2019.


Two-Stage Exchange Arthroplasty for Periprosthetic Joint Infection: The Rate and Reason for the Attrition After the First Stage.

Wang Q, Goswami K, Kuo FC, Xu C, Tan TL, Parvizi J.

J Arthroplasty. 2019 Jun 15. pii: S0883-5403(19)30591-1. doi: 10.1016/j.arth.2019.06.021. [Epub ahead of print]


Development and Validation of an Evidence-Based Algorithm for Diagnosing Periprosthetic Joint Infection.

Shohat N, Tan TL, Della Valle CJ, Calkins TE, George J, Higuera C, Parvizi J.

J Arthroplasty. 2019 Jun 13. pii: S0883-5403(19)30586-8. doi: 10.1016/j.arth.2019.06.016. [Epub ahead of print]


Coverage and determinants of influenza vaccine among pregnant women: a cross-sectional study.

Offeddu V, Tam CC, Yong TT, Tan LK, Thoon KC, Lee N, Tan TC, Yeo GSH, Yung CF.

BMC Public Health. 2019 Jul 5;19(1):890. doi: 10.1186/s12889-019-7172-8.


Creating vessel elements in vitro: Towards a comprehensive understanding of the molecular basis of xylem vessel element differentiation.

Tan TT, Demura T, Ohtani M.

Plant Biotechnol (Tokyo). 2019;36(1):1-6. doi: 10.5511/plantbiotechnology.18.1119b.


miR‑1 reverses multidrug resistance in gastric cancer cells via downregulation of sorcin through promoting the accumulation of intracellular drugs and apoptosis of cells.

Deng LM, Tan T, Zhang TY, Xiao XF, Gu H.

Int J Oncol. 2019 Jun 25. doi: 10.3892/ijo.2019.4831. [Epub ahead of print]


Clinical and dosimetric predictors of physician and patient reported xerostomia following intensity modulated radiotherapy for nasopharyngeal cancer - A prospective cohort analysis.

Sommat K, Hussain A, Ong WS, Yit NLF, Khoo JBK, Soong YL, Wee JTS, Fong KW, Tan TWK.

Radiother Oncol. 2019 Jun 29;138:149-157. doi: 10.1016/j.radonc.2019.05.023. [Epub ahead of print]


Quality of reporting on thoracic radiotherapy technique in prospective lung cancer trials: A systematic review.

Soon YY, Chen D, Tan TH, Tey JCS.

Medicine (Baltimore). 2019 Jun;98(26):e16124. doi: 10.1097/MD.0000000000016124.


High-sensitivity off-axis integrated cavity output spectroscopy implementing wavelength modulation and white noise perturbation.

Wang J, Tian X, Dong Y, Chen J, Tan T, Zhu G, Chen W, Gao X.

Opt Lett. 2019 Jul 1;44(13):3298-3301. doi: 10.1364/OL.44.003298.


Overexpression of microRNA-620 facilitates the resistance of triple negative breast cancer cells to gemcitabine treatment by targeting DCTD.

Wu C, Zhao A, Tan T, Wang Y, Shen Z.

Exp Ther Med. 2019 Jul;18(1):550-558. doi: 10.3892/etm.2019.7601. Epub 2019 May 23.


2019 John Insall Award: Fructosamine is a better glycaemic marker compared with glycated haemoglobin (HbA1C) in predicting adverse outcomes following total knee arthroplasty: a prospective multicentre study.

Shohat N, Tarabichi M, Tan TL, Goswami K, Kheir M, Malkani AL, Shah RP, Schwarzkopf R, Parvizi J.

Bone Joint J. 2019 Jul;101-B(7_Supple_C):3-9. doi: 10.1302/0301-620X.101B7.BJJ-2018-1418.R1.


Reduced opioid requirements following unicompartmental knee arthroplasty compared with total knee arthroplasty.

Kalbian IL, Tan TL, Rondon AJ, Bonaddio VA, Klement MR, Foltz C, Lonner JH.

Bone Joint J. 2019 Jul;101-B(7_Supple_C):22-27. doi: 10.1302/0301-620X.101B7.BJJ-2018-1454.R1.


Application of 18F-FDG PET-CT in the management of pulmonary nodule and mass - a pictorial review.

Wong TH, Tan TH, George UR, Kow KS, Liam CK.

Med J Malaysia. 2019 Jun;74(3):250-256.


Superior emotional regulating effects of creative cognitive reappraisal.

Wu X, Guo T, Tan T, Zhang W, Qin S, Fan J, Luo J.

Neuroimage. 2019 Jun 26;200:540-551. doi: 10.1016/j.neuroimage.2019.06.061. [Epub ahead of print]


Interface-mediated Kirkendall effect and nanoscale void migration in bimetallic nanoparticles during interdiffusion.

Chee SW, Wong ZM, Baraissov Z, Tan SF, Tan TL, Mirsaidov U.

Nat Commun. 2019 Jun 27;10(1):2831. doi: 10.1038/s41467-019-10623-0.


One hypervirulent clone, sequence type 283, accounts for a large proportion of invasive Streptococcus agalactiae isolated from humans and diseased tilapia in Southeast Asia.

Barkham T, Zadoks RN, Azmai MNA, Baker S, Bich VTN, Chalker V, Chau ML, Dance D, Deepak RN, van Doorn HR, Gutierrez RA, Holmes MA, Huong LNP, Koh TH, Martins E, Mehershahi K, Newton P, Ng LC, Phuoc NN, Sangwichian O, Sawatwong P, Surin U, Tan TY, Tang WY, Thuy NV, Turner P, Vongsouvath M, Zhang D, Whistler T, Chen SL.

PLoS Negl Trop Dis. 2019 Jun 27;13(6):e0007421. doi: 10.1371/journal.pntd.0007421. eCollection 2019 Jun.


Interaction between Antibiotic Resistance, Resistance Genes and Treatment Response for Urinary Tract Infections in Primary Care.

Ho HJ, Tan MX, Chen MI, Tan TY, Koo SH, Koong AYL, Ng LP, Hu PL, Tan KT, Moey PKS, Koh EYL, Wong CS, Lye DC, Tan NC.

J Clin Microbiol. 2019 Jun 26. pii: JCM.00143-19. doi: 10.1128/JCM.00143-19. [Epub ahead of print]


Surgical risk factors of retroperitoneal teratoma resection in children.

Yang T, Li H, Li J, Wu H, Hu C, Tan T, Yang J, Pan J, Zou Y.

J Pediatr Surg. 2019 Jul;54(7):1495-1499. doi: 10.1016/j.jpedsurg.2018.09.020. Epub 2018 Oct 10.


An Asia Pacific Consensus on Perinatal Nutrition and Breastfeeding.

Tan KH, Tan TYT, Chua MC, Kor-Anantakul O.

Ann Nutr Metab. 2019 Jun 25:1-2. doi: 10.1159/000501192. [Epub ahead of print] No abstract available.


Impact of AKI on Urinary Protein Excretion: Analysis of Two Prospective Cohorts.

Hsu CY, Hsu RK, Liu KD, Yang J, Anderson A, Chen J, Chinchilli VM, Feldman HI, Garg AX, Hamm L, Himmelfarb J, Kaufman JS, Kusek JW, Parikh CR, Ricardo AC, Rosas SE, Saab G, Sha D, Siew ED, Sondheimer J, Taliercio JJ, Yang W, Go AS; Chronic Renal Insufficiency Cohort (CRIC) Study Investigators and the Assessment, Serial Evaluation, and Subsequent Sequelae of Acute Kidney Injury (ASSESS-AKI) Study.

J Am Soc Nephrol. 2019 Jul;30(7):1271-1281. doi: 10.1681/ASN.2018101036. Epub 2019 Jun 24.


Comparison of Risk for End-Stage Renal Disease Between Physicians and the General Population: A Nationwide Population-Based Cohort Study.

Yen CK, Tan TH, Feng IJ, Ho CH, Hsu CC, Lin HJ, Wang JJ, Huang CC.

Int J Environ Res Public Health. 2019 Jun 22;16(12). pii: E2211. doi: 10.3390/ijerph16122211.


Pulsed-field gel electrophoresis (PFGE): A review of the "gold standard" for bacteria typing and current alternatives.

Neoh HM, Tan XE, Sapri HF, Tan TL.

Infect Genet Evol. 2019 Jun 22;74:103935. doi: 10.1016/j.meegid.2019.103935. [Epub ahead of print] Review.


Solitary fibrous tumour of the parotid gland: a case report and a 15-year literature review.

Lim DWJ, Tan TSH, Tan JL, Venkateswaran K.

AME Case Rep. 2019 May 24;3:14. doi: 10.21037/acr.2019.04.05. eCollection 2019.


Postural control adaptation to optic flow in children and adults with autism spectrum disorder.

Lim YH, Lee HC, Falkmer T, Allison GT, Tan T, Lee WL, Morris SL.

Gait Posture. 2019 Jun 10;72:175-181. doi: 10.1016/j.gaitpost.2019.06.007. [Epub ahead of print]


Analgesia, anaesthesia and obstetric outcome in women with inherited bleeding disorders.

Boyd SC, O'Connor AD, Horan MA, Dicker P, Manning C, Lynch C, Regan C, Ryan K, Tan T, Byrne BM.

Eur J Obstet Gynecol Reprod Biol. 2019 Aug;239:60-63. doi: 10.1016/j.ejogrb.2019.05.043. Epub 2019 Jun 4.


A bio-inspired strategy for enhanced hydrogen evolution: carbonate ions as hole vehicles to promote carrier separation.

Tan T, Xie J, Wang W, Ping H, Ma P, Xie H, Wang W, Fu Z.

Nanoscale. 2019 Jun 20;11(24):11451-11456. doi: 10.1039/c9nr04057a.


Surgical Treatment of Chronic Periprosthetic Joint Infection: Fate of Spacer Exchanges.

Tan TL, Goswami K, Kheir MM, Xu C, Wang Q, Parvizi J.

J Arthroplasty. 2019 Apr 12. pii: S0883-5403(19)30348-1. doi: 10.1016/j.arth.2019.04.016. [Epub ahead of print]


LINC00673 rs11655237 C>T Polymorphism Impacts Hepatoblastoma Susceptibility in Chinese Children.

Yang T, Li J, Wen Y, Tan T, Yang J, Pan J, Hu C, Yao Y, Zhang J, Xin Y, Li S, Xia H, He J, Zou Y.

Front Genet. 2019 May 24;10:506. doi: 10.3389/fgene.2019.00506. eCollection 2019.


Self-Directed Home Exercises vs Outpatient Physical Therapy After Total Knee Arthroplasty: Value and Outcomes Following a Protocol Change.

Wang WL, Rondon AJ, Tan TL, Wilsman J, Purtill JJ.

J Arthroplasty. 2019 May 16. pii: S0883-5403(19)30494-2. doi: 10.1016/j.arth.2019.05.020. [Epub ahead of print]


Combined GLP-1, Oxyntomodulin, and Peptide YY Improves Body Weight and Glycemia in Obesity and Prediabetes/Type 2 Diabetes: A Randomized Single-Blinded Placebo Controlled Study.

Behary P, Tharakan G, Alexiadou K, Johnson N, Wewer Albrechtsen NJ, Kenkre J, Cuenco J, Hope D, Anyiam O, Choudhury S, Alessimii H, Poddar A, Minnion J, Doyle C, Frost G, Le Roux C, Purkayastha S, Moorthy K, Dhillo W, Holst JJ, Ahmed AR, Prevost AT, Bloom SR, Tan TM.

Diabetes Care. 2019 Jun 8. pii: dc190449. doi: 10.2337/dc19-0449. [Epub ahead of print]


Adjunctive liraglutide treatment in patients with persistent or recurrent type 2 diabetes after metabolic surgery (GRAVITAS): a randomised, double-blind, placebo-controlled trial.

Miras AD, Pérez-Pevida B, Aldhwayan M, Kamocka A, McGlone ER, Al-Najim W, Chahal H, Batterham RL, McGowan B, Khan O, Greener V, Ahmed AR, Petrie A, Scholtz S, Bloom SR, Tan TM.

Lancet Diabetes Endocrinol. 2019 Jul;7(7):549-559. doi: 10.1016/S2213-8587(19)30157-3. Epub 2019 Jun 4.


Tracking Foot Drop Recovery Following Lumbar-Spine Surgery, Applying Multiclass Gait Classification Using Machine Learning Techniques.

Sharif Bidabadi S, Tan T, Murray I, Lee G.

Sensors (Basel). 2019 Jun 4;19(11). pii: E2542. doi: 10.3390/s19112542.


ST-segment elevation myocardial infarction with non-chest pain presentation at the Emergency Department: Insights from the Singapore Myocardial Infarction Registry.

Pong JZ, Ho AFW, Tan TXZ, Zheng H, Pek PP, Sia CH, Hausenloy DJ, Ong MEH.

Intern Emerg Med. 2019 Jun 5. doi: 10.1007/s11739-019-02122-3. [Epub ahead of print]


SNAI1 recruits HDAC1 to suppress SNAI2 transcription during epithelial to mesenchymal transition.

Sundararajan V, Tan M, Tan TZ, Ye J, Thiery JP, Huang RY.

Sci Rep. 2019 Jun 5;9(1):8295. doi: 10.1038/s41598-019-44826-8.

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