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Utility of lumbar puncture after a normal brain computed tomography scan in patients presenting to the emergency department with suspected subarachnoid haemorrhage: A new more rational approach?

Pouryahya P, Haydon R, Meyer A, Easaw-Mamutil N, Tan SYZ, Teng GHW.

Emerg Med Australas. 2020 Mar 20. doi: 10.1111/1742-6723.13502. [Epub ahead of print]


Investigation of three clusters of COVID-19 in Singapore: implications for surveillance and response measures.

Pung R, Chiew CJ, Young BE, Chin S, Chen MI, Clapham HE, Cook AR, Maurer-Stroh S, Toh MPHS, Poh C, Low M, Lum J, Koh VTJ, Mak TM, Cui L, Lin RVTP, Heng D, Leo YS, Lye DC, Lee VJM; Singapore 2019 Novel Coronavirus Outbreak Research Team.

Lancet. 2020 Mar 28;395(10229):1039-1046. doi: 10.1016/S0140-6736(20)30528-6. Epub 2020 Mar 17.


Mitochondrial Dysfunction in Age-Related Metabolic Disorders.

Natarajan V, Chawla R, Mah T, Vivekanandan R, Tan SY, Sato PY, Mallilankaraman K.

Proteomics. 2020 Mar 4:e1800404. doi: 10.1002/pmic.201800404. [Epub ahead of print] Review.


Approach to evaluation of choledocholithiasis in patient with or without acute cholangitis.

Tan SY, Chong CF, Chong VH.

QJM. 2020 Mar 3. pii: hcaa076. doi: 10.1093/qjmed/hcaa076. [Epub ahead of print] No abstract available.


Epidemiologic Features and Clinical Course of Patients Infected With SARS-CoV-2 in Singapore.

Young BE, Ong SWX, Kalimuddin S, Low JG, Tan SY, Loh J, Ng OT, Marimuthu K, Ang LW, Mak TM, Lau SK, Anderson DE, Chan KS, Tan TY, Ng TY, Cui L, Said Z, Kurupatham L, Chen MI, Chan M, Vasoo S, Wang LF, Tan BH, Lin RTP, Lee VJM, Leo YS, Lye DC; Singapore 2019 Novel Coronavirus Outbreak Research Team.

JAMA. 2020 Mar 3. doi: 10.1001/jama.2020.3204. [Epub ahead of print]


Spontaneous spinal epidural haematoma following intra-arterial catheter-directed thrombolysis: A case report.

Shannon NB, Kumar P, Tay KH, Tan SY, Chng SP, Tay HT.

SAGE Open Med Case Rep. 2020 Feb 10;8:2050313X20906741. doi: 10.1177/2050313X20906741. eCollection 2020.


Preoperative Weight Loss via Very Low Caloric Diet (VLCD) and Its Effect on Outcomes After Bariatric Surgery.

Tan SYT, Loi PL, Lim CH, Ganguly S, Syn N, Tham KW, Tan HC, Chan WH, Wong HM, Lee PC.

Obes Surg. 2020 Feb 19. doi: 10.1007/s11695-020-04446-y. [Epub ahead of print]


[Treatment of postprandial discomfort syndrome in the elderly: a multi-centered prospective randomized controlled clinical study].

Wang GS, Xu L, Chen HT, Shi LP, Huang MJ, Xi L, Xu LS, Wang F, Li HY, Li S, Zhang YJ, Tan SY, Hong RT, Lyu NH, Ye M, Gan HT, Liu M, Wu BY; Committee of Geriatric Gastroenterology, Chinese Society of Gastroenterology.

Zhonghua Nei Ke Za Zhi. 2020 Feb 1;59(2):117-123. doi: 10.3760/cma.j.issn.0578-1426.2020.02.005. Chinese.


Allan MacLeod Cormack (1924-1998): Discoverer of computerised axial tomography.

Tan SY, Poole PS.

Singapore Med J. 2020 Jan;61(1):4-5. doi: 10.11622/smedj.2020003. No abstract available.


Mapping patterns of abiotic and biotic stress resilience uncovers conservation gaps and breeding potential of Vigna wild relatives.

van Zonneveld M, Rakha M, Tan SY, Chou YY, Chang CH, Yen JY, Schafleitner R, Nair R, Naito K, Solberg SØ.

Sci Rep. 2020 Feb 7;10(1):2111. doi: 10.1038/s41598-020-58646-8.


[Effect of metformin on mitochondrial pathway of apoptosis and oxidative stress in cell model of nonalcoholic fatty liver disease].

Wu PB, Song Q, Yu YJ, Yu HG, Luo HS, Tan SY.

Zhonghua Gan Zang Bing Za Zhi. 2020 Jan 20;28(1):64-68. doi: 10.3760/cma.j.issn.1007-3418.2020.01.015. Chinese.


Charcot's triad.

Tan SY, Chong CF, Chong VH.

QJM. 2020 Feb 3. pii: hcaa019. doi: 10.1093/qjmed/hcaa019. [Epub ahead of print] No abstract available.


Application of an ex-vivo drug sensitivity platform towards achieving complete remission in a refractory T-cell lymphoma.

de Mel S, Rashid MBM, Zhang XY, Goh J, Lee CT, Poon LM, Chan EHL, Liu X, Chng WJ, Chee YL, Lee J, Yuen YC, Lim JQ, Chia BKH, Laurensia Y, Huang D, Pang WL, Cheah DMZ, Wong EKY, Ong CK, Tang T, Lim ST, Ng SB, Tan SY, Loi HY, Tan LK, Chow EK, Jeyasekharan AD.

Blood Cancer J. 2020 Jan 27;10(1):9. doi: 10.1038/s41408-020-0276-7. No abstract available.


Tuberculosis and Melioidosis at Distinct Sites Occurring Simultaneously.

Tan SY.

Case Rep Infect Dis. 2020 Jan 3;2020:9818129. doi: 10.1155/2020/9818129. eCollection 2020.


Barrett's Esophagus and Intestinal Metaplasia of the Gastroesophageal Junction in Children: A Clinicopathologic Study.

Putra J, Arva NC, Tan SY, Melin-Aldana H, Bass LM, Mitchell PD, Fox VL, Goldsmith JD.

J Pediatr Gastroenterol Nutr. 2020 Jan 23. doi: 10.1097/MPG.0000000000002640. [Epub ahead of print]


Restoring apoptosis dysregulation using survivin inhibitor in nasopharyngeal cancer.

Shi J, Tan SY, Lee AZE, Zhang S, Sasidharan SL, Wong B, Tan MH, Lim CM.

Head Neck. 2020 Jan 11. doi: 10.1002/hed.26068. [Epub ahead of print]


A humanized mouse model to study mast cells mediated cutaneous adverse drug reactions.

Mencarelli A, Gunawan M, Yong KSM, Bist P, Tan WWS, Tan SY, Liu M, Huang EK, Fan Y, Chan JKY, Choi HW, Abraham SN, Chen Q.

J Leukoc Biol. 2020 Jan 10. doi: 10.1002/JLB.3MA1219-210RR. [Epub ahead of print]


Non-nutritive sweeteners are in concomitant with the formation of endogenous and exogenous advanced glycation end-products.

Deo P, Chern C, Peake B, Tan SY.

Int J Food Sci Nutr. 2020 Jan 9:1-9. doi: 10.1080/09637486.2020.1712683. [Epub ahead of print]


Recreating Physiological Environments In Vitro: Design Rules for Microfluidic-Based Vascularized Tissue Constructs.

Tan SY, Leung Z, Wu AR.

Small. 2020 Mar;16(9):e1905055. doi: 10.1002/smll.201905055. Epub 2020 Jan 8. Review.


Late-onset renal hypertrophy and dysfunction in mice lacking CTRP1.

Rodriguez S, Little HC, Daneshpajouhnejad P, Shepard BD, Tan SY, Wolfe A, Cheema MU, Jandu S, Woodward OM, Talbot CC Jr, Berkowitz DE, Rosenberg AZ, Pluznick JL, Wong GW.

FASEB J. 2020 Feb;34(2):2657-2676. doi: 10.1096/fj.201900558RR. Epub 2019 Dec 26.


Switching from Ticagrelor to Clopidogrel in Asian Patients with ST-Elevated Myocardial Infarction - A Time Dependent Analysis Study.

Koh L, Kim JH, Tan SYD, Leong WQ, Syed SI, Leow KL, Wee WLE.

Acta Cardiol Sin. 2020 Jan;36(1):8-15. doi: 10.6515/ACS.202001_36(1).20190627A.


Long-term Pulpal and Restorative Outcomes of Pulpotomy in Mature Permanent Teeth.

Tan SY, Yu VSH, Lim KC, Tan BCK, Neo CLJ, Shen L, Messer HH.

J Endod. 2020 Mar;46(3):383-390. doi: 10.1016/j.joen.2019.11.009. Epub 2020 Jan 2.


C-MYC, BCL2 and BCL6 Translocation in B-cell Non-Hodgkin Lymphoma Cases.

Salam DSDA, Thit EE, Teoh SH, Tan SY, Peh SC, Cheah SC.

J Cancer. 2020 Jan 1;11(1):190-198. doi: 10.7150/jca.36954. eCollection 2020.


Genetic risk of extranodal natural killer T-cell lymphoma: a genome-wide association study in multiple populations.

Lin GW, Xu C, Chen K, Huang HQ, Chen J, Song B, Chan JKC, Li W, Liu W, Shih LY, Chuang WY, Kim WS, Tan W, Peng RJ, Laurensia Y, Cheah DMZ, Huang D, Cheng CL, Su YJ, Tan SY, Ng SB, Tang TPL, Han K, Wang VY, Jia WH, Pei Z, Li YJ, Gao S, Shi Y, Hu Z, Zhang F, Zhang B, Zeng YX, Shen H, He L, Ong CK, Lim ST, Chanock S, Kwong YL, Lin D, Rothman N, Khor CC, Lan Q, Bei JX; International NKTCL Working Group.

Lancet Oncol. 2020 Feb;21(2):306-316. doi: 10.1016/S1470-2045(19)30799-5. Epub 2019 Dec 23.


Cutaneous Eruptions from Ibrutinib Resembling EGFR Inhibitor-Induced Dermatologic Adverse Events.

Singer S, Tan SY, Dewan AK, Davids M, LaCasce AS, Treon SP, LeBoeuf NR.

J Am Acad Dermatol. 2019 Dec 20. pii: S0190-9622(19)33308-0. doi: 10.1016/j.jaad.2019.12.031. [Epub ahead of print]


Autophagic Degradation of Misfolded Nuclear Receptor Co-repressor (NCoR) Is Linked to the Growth of Tumor Cells in HBX Positive Hepatocellular Carcinoma (HCC).

Tan SY, Visvanathan S, Abu Hassan R, Khan M.

Front Oncol. 2019 Dec 3;9:1335. doi: 10.3389/fonc.2019.01335. eCollection 2019.


Decreased expression of SorCS1 in colorectal cancer: An independent predictor of poor prognosis.

Huang PZ, Peng SY, Yu HC, Huang L, Yao Q, Wang XL, Tan SY, Zhou JM, Wang PN, Huang AP, Bai LL, Luo YX, Huang MJ.

Neoplasma. 2020 Jan;67(1):119-128. doi: 10.4149/neo_2019_190221N146. Epub 2019 Dec 9.


Epstein-Barr virus-associated T- and NK-cell lymphoproliferative diseases: an update and diagnostic approach.

Hue SS, Oon ML, Wang S, Tan SY, Ng SB.

Pathology. 2020 Jan;52(1):111-127. doi: 10.1016/j.pathol.2019.09.011. Epub 2019 Nov 22. Review.


Harnessing technology and molecular analysis to understand the development of cardiovascular diseases in Asia: a prospective cohort study (SingHEART).

Yap J, Lim WK, Sahlén A, Chin CW, Chew KMY, Davila S, Allen J, Goh V, Tan SY, Tan P, Lam CSP, Cook SA, Yeo KK.

BMC Cardiovasc Disord. 2019 Nov 21;19(1):259. doi: 10.1186/s12872-019-1248-3.


Clinical significance of aberrant microRNAs expression in predicting disease relapse/refractoriness to treatment in diffuse large B-cell lymphoma: A meta-analysis.

Ting CY, Liew SM, Price A, Gan GG, Bee-Lan Ong D, Tan SY, Bee PC.

Crit Rev Oncol Hematol. 2019 Dec;144:102818. doi: 10.1016/j.critrevonc.2019.102818. Epub 2019 Nov 1. Review.


Establishment of a new genus for Nudina xizangensis Fang, 2000 (Lepidoptera, Erebidae, Arctiinae, Lithosiini).

Huang SY, Tan SY, Wang M, Fan XL.

Zootaxa. 2019 Oct 8;4683(2):zootaxa.4683.2.5. doi: 10.11646/zootaxa.4683.2.5.


Is partial nephrectomy worthwhile over radical nephrectomy for localised renal cortical tumours less than 7 cm in geriatric patients?

Lam JKJ, Tan SY, Chong KT.

Singapore Med J. 2019 Nov 4. doi: 10.11622/smedj.2019136. [Epub ahead of print]


Christiaan Barnard (1922-2001): First heart transplant surgeon.

Tan SY, Linskey K.

Singapore Med J. 2019 Oct;60(10):495-496. doi: 10.11622/smedj.2019127. No abstract available.


Digital phenotyping by consumer wearables identifies sleep-associated markers of cardiovascular disease risk and biological aging.

Teo JX, Davila S, Yang C, Hii AA, Pua CJ, Yap J, Tan SY, Sahlén A, Chin CW, Teh BT, Rozen SG, Cook SA, Yeo KK, Tan P, Lim WK.

Commun Biol. 2019 Oct 4;2:361. doi: 10.1038/s42003-019-0605-1. eCollection 2019.


Lifestyle intervention for gastroesophageal reflux disease: a national multicenter survey of lifestyle factor effects on gastroesophageal reflux disease in China.

Yuan LZ, Yi P, Wang GS, Tan SY, Huang GM, Qi LZ, Jia Y, Wang F.

Therap Adv Gastroenterol. 2019 Sep 25;12:1756284819877788. doi: 10.1177/1756284819877788. eCollection 2019.


Clinical impact of the cell-of-origin classification based on immunohistochemistry criteria and Lymph2Cx of diffuse large B-Cell lymphoma patients in a South-east Asian population: a single center experience and review of the literature.

Lee J, Hue SS, Ko SQ, Tan SY, Liu X, Girard LP, Chan EHL, De Mel S, Jeyasekharan A, Chee YL, Koh LP, Poon LM.

Expert Rev Hematol. 2019 Dec;12(12):1095-1105. doi: 10.1080/17474086.2019.1677152. Epub 2019 Oct 19.


Orbital-Selective Kondo Entanglement and Antiferromagnetic Order in USb_{2}.

Chen QY, Luo XB, Xie DH, Li ML, Ji XY, Zhou R, Huang YB, Zhang W, Feng W, Zhang Y, Huang L, Hao QQ, Liu Q, Zhu XG, Liu Y, Zhang P, Lai XC, Si Q, Tan SY.

Phys Rev Lett. 2019 Sep 6;123(10):106402. doi: 10.1103/PhysRevLett.123.106402.


RNA-Binding Protein ZFP36L1 Suppresses Hypoxia and Cell-Cycle Signaling.

Loh XY, Sun QY, Ding LW, Mayakonda A, Venkatachalam N, Yeo MS, Silva TC, Xiao JF, Doan NB, Said JW, Ran XB, Zhou SQ, Dakle P, Shyamsunder P, Koh AP, Huang RY, Berman BP, Tan SY, Yang H, Lin DC, Koeffler HP.

Cancer Res. 2020 Jan 15;80(2):219-233. doi: 10.1158/0008-5472.CAN-18-2796. Epub 2019 Sep 24.


Gonadal Tissue Cryopreservation for Children with Differences of Sex Development.

Johnson EK, Finlayson C, Finney EL, Harris CJ, Tan SY, Laronda MM, Lockart BA, Chen D, Rowell EE, Cheng EY, Yerkes EB.

Horm Res Paediatr. 2019;92(2):84-91. doi: 10.1159/000502644. Epub 2019 Sep 11.


Synthesis and Characterization of Iron Phthalocyanine Supported on Graphene Oxide and Catalysis of Adrenaline.

Peng C, Tan SY, Li MT.

J Nanosci Nanotechnol. 2020 Apr 1;20(4):2195-2204. doi: 10.1166/jnn.2020.17202.


An unintended consequence of provider payment reform: The case of capitation grants in the National Health Insurance reform of Indonesia.

Tan SY, Qian J.

Int J Health Plann Manage. 2019 Oct;34(4):e1688-e1710. doi: 10.1002/hpm.2883. Epub 2019 Aug 18.


Rosalyn Yalow (1921-2011): Madame Curie from the Bronx.

Tan SY, Bracha A.

Singapore Med J. 2019 Jul;60(7):337-338. doi: 10.11622/smedj.2019073. No abstract available.


Differentiating Parkinson's disease motor subtypes using automated volume-based morphometry incorporating white matter and deep gray nuclear lesion load.

Fang E, Ann CN, Maréchal B, Lim JX, Tan SYZ, Li H, Gan J, Tan EK, Chan LL.

J Magn Reson Imaging. 2020 Mar;51(3):748-756. doi: 10.1002/jmri.26887. Epub 2019 Jul 31.


When West Meets East: The Origins and Spread of Weedy Rice Between Continental and Island Southeast Asia.

Neik TX, Chai JY, Tan SY, Sudo MPS, Cui Y, Jayaraj J, Teo SS, Olsen KM, Song BK.

G3 (Bethesda). 2019 Sep 4;9(9):2941-2950. doi: 10.1534/g3.119.400021.


The contribution of MYC and PLK1 expression to proliferative capacity in diffuse large B-cell lymphoma.

Oon ML, Hoppe MM, Fan S, Phyu T, Phuong HM, Tan SY, Hue SS, Wang S, Poon LM, Chan HLE, Lee J, Chee YL, Chng WJ, de Mel S, Liu X, Jeyasekharan AD, Ng SB.

Leuk Lymphoma. 2019 Dec;60(13):3214-3224. doi: 10.1080/10428194.2019.1633629. Epub 2019 Jul 1.


Diagnosis of obstructive coronary artery disease using computed tomography angiography in patients with stable chest pain depending on clinical probability and in clinically important subgroups: meta-analysis of individual patient data.

Haase R, Schlattmann P, Gueret P, Andreini D, Pontone G, Alkadhi H, Hausleiter J, Garcia MJ, Leschka S, Meijboom WB, Zimmermann E, Gerber B, Schoepf UJ, Shabestari AA, Nørgaard BL, Meijs MFL, Sato A, Ovrehus KA, Diederichsen ACP, Jenkins SMM, Knuuti J, Hamdan A, Halvorsen BA, Mendoza-Rodriguez V, Rochitte CE, Rixe J, Wan YL, Langer C, Bettencourt N, Martuscelli E, Ghostine S, Buechel RR, Nikolaou K, Mickley H, Yang L, Zhang Z, Chen MY, Halon DA, Rief M, Sun K, Hirt-Moch B, Niinuma H, Marcus RP, Muraglia S, Jakamy R, Chow BJ, Kaufmann PA, Tardif JC, Nomura C, Kofoed KF, Laissy JP, Arbab-Zadeh A, Kitagawa K, Laham R, Jinzaki M, Hoe J, Rybicki FJ, Scholte A, Paul N, Tan SY, Yoshioka K, Röhle R, Schuetz GM, Schueler S, Coenen MH, Wieske V, Achenbach S, Budoff MJ, Laule M, Newby DE, Dewey M; COME-CCT Consortium.

BMJ. 2019 Jun 12;365:l1945. doi: 10.1136/bmj.l1945.


[Paying attention to the prevention and treatment of hepatic injury induced by anti-tuberculosis drugs].

Tan SY.

Zhonghua Jie He He Hu Xi Za Zhi. 2019 May 12;42(5):326-329. doi: 10.3760/cma.j.issn.1001-0939.2019.05.003. Chinese.


Insecticidal Activity of a Vip3Ab1 Chimera Is Conferred by Improved Protein Stability in the Midgut of Spodoptera eridania.

Bowling AJ, Sopko MS, Tan SY, Larsen CM, Pence HE, Zack MD.

Toxins (Basel). 2019 May 16;11(5). pii: E276. doi: 10.3390/toxins11050276.


Joseph Murray (1919-2012): First transplant surgeon.

Tan SY, Merchant J.

Singapore Med J. 2019 Apr;60(4):162-163. doi: 10.11622/smedj.2019032. No abstract available.

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