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A Systematic Review and Meta-Analyses of the Association Between Anti-Hypertensive Classes and the Risk of Falls Among Older Adults.

Ang HT, Lim KK, Kwan YH, Tan PS, Yap KZ, Banu Z, Tan CS, Fong W, Thumboo J, Ostbye T, Low LL.

Drugs Aging. 2018 Jun 23. doi: 10.1007/s40266-018-0561-3. [Epub ahead of print] Review.


Addition of abiraterone, docetaxel, bisphosphonate, celecoxib or combinations to androgen-deprivation therapy (ADT) for metastatic hormone-sensitive prostate cancer (mHSPC): a network meta-analysis.

Tan PS, Aguiar P Jr, Haaland B, Lopes G.

Prostate Cancer Prostatic Dis. 2018 Jun 6. doi: 10.1038/s41391-018-0055-8. [Epub ahead of print]


Comparison of Caesarean sections and instrumental deliveries at full cervical dilatation: a retrospective review.

Tan PS, Tan JKH, Tan EL, Tan LK.

Singapore Med J. 2018 Apr 19. doi: 10.11622/smedj.2018040. [Epub ahead of print]


Two Differential Binding Mechanisms of FG-Nucleoporins and Nuclear Transport Receptors.

Tan PS, Aramburu IV, Mercadante D, Tyagi S, Chowdhury A, Spitz D, Shammas SL, Gräter F, Lemke EA.

Cell Rep. 2018 Mar 27;22(13):3660-3671. doi: 10.1016/j.celrep.2018.03.022.


Overview of systematic reviews assessing the evidence for shorter versus longer duration antibiotic treatment for bacterial infections in secondary care.

Onakpoya IJ, Walker AS, Tan PS, Spencer EA, Gbinigie OA, Cook J, Llewelyn MJ, Butler CC.

PLoS One. 2018 Mar 28;13(3):e0194858. doi: 10.1371/journal.pone.0194858. eCollection 2018.


Comparative effectiveness of immune-checkpoint inhibitors for previously treated advanced non-small cell lung cancer - A systematic review and network meta-analysis of 3024 participants.

Tan PS, Aguiar P Jr, Haaland B, Lopes G.

Lung Cancer. 2018 Jan;115:84-88. doi: 10.1016/j.lungcan.2017.11.017. Epub 2017 Nov 22.


Editorial: hepatocellular carcinoma risk in the era of direct-acting anti-virals-is the case closed?

Tan PS, Lim SG.

Aliment Pharmacol Ther. 2018 Jan;47(2):308-309. doi: 10.1111/apt.14437. No abstract available.


Enhancing vaccine antibody responses by targeting Clec9A on dendritic cells.

Park HY, Tan PS, Kavishna R, Ker A, Lu J, Chan CEZ, Hanson BJ, MacAry PA, Caminschi I, Shortman K, Alonso S, Lahoud MH.

NPJ Vaccines. 2017 Nov 6;2:31. doi: 10.1038/s41541-017-0033-5. eCollection 2017.


Acute-on-chronic liver failure in a multi-ethnic Asian city: A comparison of patients identified by Asia-Pacific Association for the Study of the Liver and European Association for the Study of the Liver definitions.

Selva Rajoo A, Lim SG, Phyo WW, Tun T, Dan YY, Lee YM, Low HC, Lim K, Tan PS, Lee GH.

World J Hepatol. 2017 Oct 8;9(28):1133-1140. doi: 10.4254/wjh.v9.i28.1133.


Monomeric Huntingtin Exon 1 Has Similar Overall Structural Features for Wild-Type and Pathological Polyglutamine Lengths.

Warner JB 4th, Ruff KM, Tan PS, Lemke EA, Pappu RV, Lashuel HA.

J Am Chem Soc. 2017 Oct 18;139(41):14456-14469. doi: 10.1021/jacs.7b06659. Epub 2017 Oct 9.


Clinician-targeted interventions to influence antibiotic prescribing behaviour for acute respiratory infections in primary care: an overview of systematic reviews.

Tonkin-Crine SK, Tan PS, van Hecke O, Wang K, Roberts NW, McCullough A, Hansen MP, Butler CC, Del Mar CB.

Cochrane Database Syst Rev. 2017 Sep 7;9:CD012252. doi: 10.1002/14651858.CD012252.pub2. Review.


Predictors of Non-adherence to Immunosuppressive Therapy in Asian Liver Transplant Recipients.

Hartono JL, Koh T, Lee GH, Tan PS, Muthiah M, Aw MM, Madhavan K, Kow A, Lim KB.

Transplant Proc. 2017 Jul - Aug;49(6):1419-1424. doi: 10.1016/j.transproceed.2017.02.049. Erratum in: Transplant Proc. 2017 Dec;49(10 ):2422.


Meta-analysis of first-line therapies with maintenance regimens for advanced non-small-cell lung cancer (NSCLC) in molecularly and clinically selected populations.

Tan PS, Bilger M, de Lima Lopes G, Acharyya S, Haaland B.

Cancer Med. 2017 Aug;6(8):1847-1860. doi: 10.1002/cam4.1101. Epub 2017 Jul 3. Review.


Imaging-based surrogate markers of transcriptome subclasses and signatures in hepatocellular carcinoma: preliminary results.

Taouli B, Hoshida Y, Kakite S, Chen X, Tan PS, Sun X, Kihira S, Kojima K, Toffanin S, Fiel MI, Hirschfield H, Wagner M, Llovet JM.

Eur Radiol. 2017 Nov;27(11):4472-4481. doi: 10.1007/s00330-017-4844-6. Epub 2017 Apr 24.


Genetic code expansion for multiprotein complex engineering.

Koehler C, Sauter PF, Wawryszyn M, Girona GE, Gupta K, Landry JJ, Fritz MH, Radic K, Hoffmann JE, Chen ZA, Zou J, Tan PS, Galik B, Junttila S, Stolt-Bergner P, Pruneri G, Gyenesei A, Schultz C, Biskup MB, Besir H, Benes V, Rappsilber J, Jechlinger M, Korbel JO, Berger I, Braese S, Lemke EA.

Nat Methods. 2016 Dec;13(12):997-1000. doi: 10.1038/nmeth.4032. Epub 2016 Oct 17.


Liver-Resident Memory CD8+ T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection.

Fernandez-Ruiz D, Ng WY, Holz LE, Ma JZ, Zaid A, Wong YC, Lau LS, Mollard V, Cozijnsen A, Collins N, Li J, Davey GM, Kato Y, Devi S, Skandari R, Pauley M, Manton JH, Godfrey DI, Braun A, Tay SS, Tan PS, Bowen DG, Koch-Nolte F, Rissiek B, Carbone FR, Crabb BS, Lahoud M, Cockburn IA, Mueller SN, Bertolino P, McFadden GI, Caminschi I, Heath WR.

Immunity. 2016 Oct 18;45(4):889-902. doi: 10.1016/j.immuni.2016.08.011. Epub 2016 Sep 27.


Distinctive expression of interleukin-23 receptor subunits on human Th17 and γδ T cells.

Wines BD, Yap ML, Powell MS, Tan PS, Ko KK, Orlowski E, Hogarth PM.

Immunol Cell Biol. 2017 Mar;95(3):272-279. doi: 10.1038/icb.2016.93. Epub 2016 Sep 20.


Targeting CLEC9A delivers antigen to human CD141+ DC for CD4+ and CD8+T cell recognition.

Tullett KM, Leal Rojas IM, Minoda Y, Tan PS, Zhang JG, Smith C, Khanna R, Shortman K, Caminschi I, Lahoud MH, Radford KJ.

JCI Insight. 2016 May 19;1(7):e87102.


Ten-year survival in women with primary stage IV breast cancer.

Eng LG, Dawood S, Sopik V, Haaland B, Tan PS, Bhoo-Pathy N, Warner E, Iqbal J, Narod SA, Dent R.

Breast Cancer Res Treat. 2016 Nov;160(1):145-152. Epub 2016 Sep 14.


The high-affinity receptor for IgG, FcγRI, of humans and non-human primates.

Chenoweth AM, Trist HM, Tan PS, Wines BD, Hogarth PM.

Immunol Rev. 2015 Nov;268(1):175-91. doi: 10.1111/imr.12366. Review.


Molecular subclasses of hepatocellular carcinoma predict sensitivity to fibroblast growth factor receptor inhibition.

Schmidt B, Wei L, DePeralta DK, Hoshida Y, Tan PS, Sun X, Sventek JP, Lanuti M, Tanabe KK, Fuchs BC.

Int J Cancer. 2016 Mar 15;138(6):1494-505. doi: 10.1002/ijc.29893. Epub 2015 Nov 9.


Progenitor cell markers predict outcome of patients with hepatocellular carcinoma beyond Milan criteria undergoing liver transplantation.

Miltiadous O, Sia D, Hoshida Y, Fiel MI, Harrington AN, Thung SN, Tan PS, Dong H, Revill K, Chang CY, Roayaie S, Byrne TJ, Mazzaferro V, Rakela J, Florman S, Schwartz M, Llovet JM.

J Hepatol. 2015 Dec;63(6):1368-77. doi: 10.1016/j.jhep.2015.07.025. Epub 2015 Jul 26.


Clinicopathological indices to predict hepatocellular carcinoma molecular classification.

Tan PS, Nakagawa S, Goossens N, Venkatesh A, Huang T, Ward SC, Sun X, Song WM, Koh A, Canasto-Chibuque C, Deshmukh M, Nair V, Mahajan M, Zhang B, Fiel MI, Kobayashi M, Kumada H, Hoshida Y.

Liver Int. 2016 Jan;36(1):108-18. doi: 10.1111/liv.12889. Epub 2015 Jun 29.


Sedation scoring and managing abilities of intensive care nurses post educational intervention.

Ramoo V, Abdullah KL, Tan PS, Wong LP, Chua YP, Tang LY.

Nurs Crit Care. 2017 May;22(3):141-149. doi: 10.1111/nicc.12180. Epub 2015 Apr 24.


Decreased miR122 in hepatocellular carcinoma leads to chemoresistance with increased arginine.

Kishikawa T, Otsuka M, Tan PS, Ohno M, Sun X, Yoshikawa T, Shibata C, Takata A, Kojima K, Takehana K, Ohishi M, Ota S, Noyama T, Kondo Y, Sato M, Soga T, Hoshida Y, Koike K.

Oncotarget. 2015 Apr 10;6(10):8339-52.


DNA hypomethylation induces a DNA replication-associated cell cycle arrest to block hepatic outgrowth in uhrf1 mutant zebrafish embryos.

Jacob V, Chernyavskaya Y, Chen X, Tan PS, Kent B, Hoshida Y, Sadler KC.

Development. 2015 Feb 1;142(3):510-21. doi: 10.1242/dev.115980. Epub 2015 Jan 6.


A Simple and Fast Hypervolume Indicator-Based Multiobjective Evolutionary Algorithm.

Jiang S, Zhang J, Ong YS, Zhang AN, Tan PS.

IEEE Trans Cybern. 2015 Oct;45(10):2202-13. doi: 10.1109/TCYB.2014.2367526. Epub 2014 Dec 2.


Intervention to improve intensive care nurses' knowledge of sedation assessment and management.

Ramoo V, Abdullah KL, Tan PS, Wong LP, Chua PY.

Nurs Crit Care. 2016 Sep;21(5):287-94. doi: 10.1111/nicc.12105. Epub 2014 Oct 1.


A genomic and clinical prognostic index for hepatitis C-related early-stage cirrhosis that predicts clinical deterioration.

King LY, Canasto-Chibuque C, Johnson KB, Yip S, Chen X, Kojima K, Deshmukh M, Venkatesh A, Tan PS, Sun X, Villanueva A, Sangiovanni A, Nair V, Mahajan M, Kobayashi M, Kumada H, Iavarone M, Colombo M, Fiel MI, Friedman SL, Llovet JM, Chung RT, Hoshida Y.

Gut. 2015 Aug;64(8):1296-302. doi: 10.1136/gutjnl-2014-307862. Epub 2014 Aug 20.


SERPINB3 is associated with TGF-β1 and cytoplasmic β-catenin expression in hepatocellular carcinomas with poor prognosis.

Turato C, Vitale A, Fasolato S, Ruvoletto M, Terrin L, Quarta S, Ramirez Morales R, Biasiolo A, Zanus G, Zali N, Tan PS, Hoshida Y, Gatta A, Cillo U, Pontisso P.

Br J Cancer. 2014 May 27;110(11):2708-15. doi: 10.1038/bjc.2014.246. Epub 2014 May 8.


Meta-analysis of first-line therapies in advanced non-small-cell lung cancer harboring EGFR-activating mutations.

Haaland B, Tan PS, de Castro G Jr, Lopes G.

J Thorac Oncol. 2014 Jun;9(6):805-11. doi: 10.1097/JTO.0000000000000156.


Hormonal Therapeutics Enzalutamide and Abiraterone Acetate in the Treatment of Metastatic Castration-Resistant Prostate Cancer (mCRPC) Post-docetaxel-an Indirect Comparison.

Tan PS, Haaland B, Montero AJ, Kyriakopoulos CE, Lopes G.

Clin Med Insights Oncol. 2014 Mar 16;8:29-36. doi: 10.4137/CMO.S13671. eCollection 2014.


Transcriptome profiling of archived sectioned formalin-fixed paraffin-embedded (AS-FFPE) tissue for disease classification.

Kojima K, April C, Canasto-Chibuque C, Chen X, Deshmukh M, Venkatesh A, Tan PS, Kobayashi M, Kumada H, Fan JB, Hoshida Y.

PLoS One. 2014 Jan 30;9(1):e86961. doi: 10.1371/journal.pone.0086961. eCollection 2014.


Polymorphisms and interspecies differences of the activating and inhibitory FcγRII of Macaca nemestrina influence the binding of human IgG subclasses.

Trist HM, Tan PS, Wines BD, Ramsland PA, Orlowski E, Stubbs J, Gardiner EE, Pietersz GA, Kent SJ, Stratov I, Burton DR, Hogarth PM.

J Immunol. 2014 Jan 15;192(2):792-803. doi: 10.4049/jimmunol.1301554. Epub 2013 Dec 16.


Spectrally coded optical nanosectioning (SpecON) with biocompatible metal-dielectric-coated substrates.

Elsayad K, Urich A, Tan PS, Nemethova M, Small JV, Unterrainer K, Heinze KG.

Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):20069-74. doi: 10.1073/pnas.1307222110. Epub 2013 Nov 25.


C-terminal β9-strand of the cyclic nucleotide-binding homology domain stabilizes activated states of Kv11.1 channels.

Ng CA, Ke Y, Perry MD, Tan PS, Hill AP, Vandenberg JI.

PLoS One. 2013 Oct 25;8(10):e77032. doi: 10.1371/journal.pone.0077032. eCollection 2013.


Childhood drowning in Malaysia.

Hss AS, Tan PS, Hashim L.

Int J Inj Contr Saf Promot. 2014;21(1):75-80. doi: 10.1080/17457300.2013.792284. Epub 2013 May 7.


Incidence and phenotype of inflammatory bowel disease based on results from the Asia-pacific Crohn's and colitis epidemiology study.

Ng SC, Tang W, Ching JY, Wong M, Chow CM, Hui AJ, Wong TC, Leung VK, Tsang SW, Yu HH, Li MF, Ng KK, Kamm MA, Studd C, Bell S, Leong R, de Silva HJ, Kasturiratne A, Mufeena MN, Ling KL, Ooi CJ, Tan PS, Ong D, Goh KL, Hilmi I, Pisespongsa P, Manatsathit S, Rerknimitr R, Aniwan S, Wang YF, Ouyang Q, Zeng Z, Zhu Z, Chen MH, Hu PJ, Wu K, Wang X, Simadibrata M, Abdullah M, Wu JC, Sung JJ, Chan FK; Asia–Pacific Crohn's and Colitis Epidemiologic Study (ACCESS) Study Group.

Gastroenterology. 2013 Jul;145(1):158-165.e2. doi: 10.1053/j.gastro.2013.04.007. Epub 2013 Apr 9.


A meta-analysis of anastrozole in combination with fulvestrant in the first line treatment of hormone receptor positive advanced breast cancer.

Tan PS, Haaland B, Montero AJ, Lopes G.

Breast Cancer Res Treat. 2013 Apr;138(3):961-5. doi: 10.1007/s10549-013-2495-0. Epub 2013 Mar 31.


Resolution of adefovir-related nephrotoxicity by adefovir dose-reduction in patients with chronic hepatitis B.

Hartono JL, Aung MO, Dan YY, Gowans M, Lim K, Lee YM, Lee GH, Low HC, Tan PS, Thwin MA, Soon C, Chiu LL, Khoo MJ, Koay E, Lim SG.

Aliment Pharmacol Ther. 2013 Apr;37(7):710-9. doi: 10.1111/apt.12251. Epub 2013 Feb 21.


Liver disease progression and virological response: entecavir rescue still possible in the setting of rtM204I lamivudine-resistant mutation.

Tan PS, Aung MO, Dan YY, Lee YM, Lim K, Low HC, Lee GH, Thwin MA, Soon C, Lim SG.

Gut. 2013 May;62(5):801-2. doi: 10.1136/gutjnl-2012-303647. Epub 2012 Nov 9. No abstract available.


Do different lamivudine-resistant hepatitis B genotypes carry the same risk of entecavir resistance?

Lee GH, Aung MO, Dan YY, Lee YM, Mak B, Low HC, Lim K, Thwin MA, Tan PS, Lim SG.

J Med Virol. 2013 Jan;85(1):26-33. doi: 10.1002/jmv.23392. Epub 2012 Sep 28.


A dynamic plasmonic manipulation technique assisted by phase modulation of an incident optical vortex beam.

Yuan GH, Wang Q, Tan PS, Lin J, Yuan XC.

Nanotechnology. 2012 Sep 28;23(38):385204. doi: 10.1088/0957-4484/23/38/385204. Epub 2012 Sep 5.


Voltage-sensing domain mode shift is coupled to the activation gate by the N-terminal tail of hERG channels.

Tan PS, Perry MD, Ng CA, Vandenberg JI, Hill AP.

J Gen Physiol. 2012 Sep;140(3):293-306. doi: 10.1085/jgp.201110761. Epub 2012 Aug 13.


Uterine leiomyosarcoma in asian patients: validation of the revised Federation of gynecology and obstetrics staging system and identification of prognostic classifiers.

Tan PS, Koh E, Pang C, Ong WS, Ngo L, Soh LT, Quek R, Chay WY, Ho TH, Tay SK, Chew SH, Lim-Tan SK, Khoo-Tan H, Lim SL, Busmanis I, Goh LK, Chia YN, Chia WK, Lim T.

Oncologist. 2012;17(10):1286-93. doi: 10.1634/theoncologist.2012-0124. Epub 2012 Jul 24.


Exploring the meaning of hypoglycaemia to community-dwelling Singaporean Chinese adults living with type 2 diabetes mellitus.

Tan PS, Chen HC, Taylor BJ, Hegney DG.

Int J Nurs Pract. 2012 Jun;18(3):252-9. doi: 10.1111/j.1440-172X.2012.02031.x.


A comparison of surgery versus transcatheter angiographic embolization in the treatment of nonvariceal upper gastrointestinal bleeding uncontrolled by endoscopy.

Ang D, Teo EK, Tan A, Ibrahim S, Tan PS, Ang TL, Fock KM.

Eur J Gastroenterol Hepatol. 2012 Aug;24(8):929-38. doi: 10.1097/MEG.0b013e32835463bc.


The S4-S5 linker acts as a signal integrator for HERG K+ channel activation and deactivation gating.

Ng CA, Perry MD, Tan PS, Hill AP, Kuchel PW, Vandenberg JI.

PLoS One. 2012;7(2):e31640. doi: 10.1371/journal.pone.0031640. Epub 2012 Feb 16.


A study on pregnant adolescents residing in a government home: common characteristics and their views on the pregnancy.

Tan P, Tohid H, Su X, Tan K, Azimah M, Khairani O.

Malays Fam Physician. 2012 Apr 30;7(1):11-5. doi: 10.4066/MFP.2012.1710. eCollection 2012.

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