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Items: 1 to 50 of 487

1.

Mechanically and chemically defined hydrogel matrices for patient-derived colorectal tumor organoid culture.

Ng S, Tan WJ, Pek MMX, Tan MH, Kurisawa M.

Biomaterials. 2019 Oct;219:119400. doi: 10.1016/j.biomaterials.2019.119400. Epub 2019 Jul 31.

PMID:
31398570
2.

Effect of niobium content on the microstructure and Young's modulus of Ti-xNb-7Zr alloys for medical implants.

Tan MHC, Baghi AD, Ghomashchi R, Xiao W, Oskouei RH.

J Mech Behav Biomed Mater. 2019 Nov;99:78-85. doi: 10.1016/j.jmbbm.2019.07.014. Epub 2019 Jul 19.

PMID:
31344525
3.

Comparative mitogenomics of the Decapoda reveals evolutionary heterogeneity in architecture and composition.

Tan MH, Gan HM, Lee YP, Bracken-Grissom H, Chan TY, Miller AD, Austin CM.

Sci Rep. 2019 Jul 24;9(1):10756. doi: 10.1038/s41598-019-47145-0.

4.

Carrier-Enhanced Anticancer Efficacy of Sunitinib-Loaded Green Tea-Based Micellar Nanocomplex beyond Tumor-Targeted Delivery.

Yongvongsoontorn N, Chung JE, Gao SJ, Bae KH, Yamashita A, Tan MH, Ying JY, Kurisawa M.

ACS Nano. 2019 Jul 23;13(7):7591-7602. doi: 10.1021/acsnano.9b00467. Epub 2019 Jul 8.

PMID:
31262169
5.

Assessment of PARP4 as a candidate breast cancer susceptibility gene.

Prawira A, Munusamy P, Yuan J, Chan CHT, Koh GL, Shuen TWH, Hu J, Yap YS, Tan MH, Ang P, Lee ASG.

Breast Cancer Res Treat. 2019 Aug;177(1):145-153. doi: 10.1007/s10549-019-05286-w. Epub 2019 May 22.

PMID:
31119570
6.

Local and regional scale habitat heterogeneity contribute to genetic adaptation in a commercially important marine mollusc (Haliotis rubra) from southeastern Australia.

Miller AD, Hoffmann AA, Tan MH, Young M, Ahrens C, Cocomazzo M, Rattray A, Ierodiaconou DA, Treml E, Sherman CDH.

Mol Ecol. 2019 Jun;28(12):3053-3072. doi: 10.1111/mec.15128. Epub 2019 Jun 9.

PMID:
31077479
7.

Cohort study to determine the risk of pressure ulcers and developing a care bundle within a paediatric intensive care unit setting.

Smith HA, Moore Z, Tan MH.

Intensive Crit Care Nurs. 2019 Aug;53:68-72. doi: 10.1016/j.iccn.2019.04.008. Epub 2019 Apr 26.

PMID:
31036423
8.

Genome Editing in Mammalian Cell Lines using CRISPR-Cas.

Liu KI, Sutrisnoh NB, Wang Y, Tan MH.

J Vis Exp. 2019 Apr 11;(146). doi: 10.3791/59086.

PMID:
31033959
9.

De Novo assembly and characterisation of the greentail prawn (Metapenaeus bennettae) hepatopancreas transcriptome - identification of stress response and detoxification transcripts.

Armstrong EK, Miller AD, Mondon JA, Greenfield PA, Stephenson SA, Tan MH, Gan HM, Hook SE.

Mar Genomics. 2019 Apr 12. pii: S1874-7787(18)30272-1. doi: 10.1016/j.margen.2019.04.002. [Epub ahead of print]

PMID:
30987888
10.

Predicting individual knee range of motion, knee pain, and walking limitation outcomes following total knee arthroplasty.

Pua YH, Poon CL, Seah FJ, Thumboo J, Clark RA, Tan MH, Chong HC, Tan JW, Chew ES, Yeo SJ.

Acta Orthop. 2019 Apr;90(2):179-186. doi: 10.1080/17453674.2018.1560647.

11.

An Expanded Synthetic Biology Toolkit for Gene Expression Control in Acetobacteraceae.

Teh MY, Ooi KH, Danny Teo SX, Bin Mansoor ME, Shaun Lim WZ, Tan MH.

ACS Synth Biol. 2019 Apr 19;8(4):708-723. doi: 10.1021/acssynbio.8b00168. Epub 2019 Mar 22.

PMID:
30865830
12.

Factors associated with false-positive mammography at first screen in an Asian population.

Ho PJ, Bok CM, Ishak HMM, Lim LY, Liu J, Wong FY, Chia KS, Tan MH, Chay WY, Hartman M, Li J.

PLoS One. 2019 Mar 11;14(3):e0213615. doi: 10.1371/journal.pone.0213615. eCollection 2019.

13.

Cost-Effectiveness Analysis of Sunitinib versus Interferon-Alfa for First-Line Treatment of Advanced and/or Metastatic Renal Cell Carcinoma in Singapore.

Pruis SL, Aziz MIA, Pearce F, Tan MH, Wu DB, Ng K.

Int J Technol Assess Health Care. 2019 Jan;35(2):126-133. doi: 10.1017/S0266462319000059. Epub 2019 Mar 11.

PMID:
30854989
14.

Comparative sequence and methylation analysis of chloroplast and amyloplast genomes from rice.

Muniandy K, Tan MH, Song BK, Ayub Q, Rahman S.

Plant Mol Biol. 2019 May;100(1-2):33-46. doi: 10.1007/s11103-019-00841-x. Epub 2019 Feb 20.

PMID:
30788769
15.

Polymers with distinctive anticancer mechanism that kills MDR cancer cells and inhibits tumor metastasis.

Zhong G, Yang C, Liu S, Zheng Y, Lou W, Teo JY, Bao C, Cheng W, Tan JPK, Gao S, Park N, Venkataraman S, Huang Y, Tan MH, Wang X, Hedrick JL, Fan W, Yang YY.

Biomaterials. 2019 Apr;199:76-87. doi: 10.1016/j.biomaterials.2019.01.036. Epub 2019 Jan 25.

PMID:
30771551
16.

Spectrum of immune checkpoint inhibitors-induced endocrinopathies in cancer patients: a scoping review of case reports.

Tan MH, Iyengar R, Mizokami-Stout K, Yentz S, MacEachern MP, Shen LY, Redman B, Gianchandani R.

Clin Diabetes Endocrinol. 2019 Jan 22;5:1. doi: 10.1186/s40842-018-0073-4. eCollection 2019. Review.

17.

Automated Renal Cancer Grading Using Nuclear Pleomorphic Patterns.

Holdbrook DA, Singh M, Choudhury Y, Kalaw EM, Koh V, Tan HS, Kanesvaran R, Tan PH, Peng JYS, Tan MH, Lee HK.

JCO Clin Cancer Inform. 2018 Dec;2:1-12. doi: 10.1200/CCI.17.00100.

18.

Stress and burnout syndrome in health-care providers treating dengue infection: A cross-sectional study.

Boo YL, Liam CCK, Lim SY, Look ML, Tan MH, Ching SM, Wan JL, Chin PW, Hoo FK.

Med J Malaysia. 2018 Dec;73(6):371-375.

19.

Generation of mature kupffer cells from human induced pluripotent stem cells.

Tasnim F, Xing J, Huang X, Mo S, Wei X, Tan MH, Yu H.

Biomaterials. 2019 Feb;192:377-391. doi: 10.1016/j.biomaterials.2018.11.016. Epub 2018 Nov 16.

PMID:
30497023
20.

Reproductive factors, obesity and risk of colorectal cancer in a cohort of Asian women.

Wong TS, Chay WY, Tan MH, Chow KY, Lim WY.

Cancer Epidemiol. 2019 Feb;58:33-43. doi: 10.1016/j.canep.2018.10.016. Epub 2018 Nov 15.

PMID:
30448606
21.

Author Correction: Reference component analysis of single-cell transcriptomes elucidates cellular heterogeneity in human colorectal tumors.

Li H, Courtois ET, Sengupta D, Tan Y, Chen KH, Goh JJL, Kong SL, Chua C, Hon LK, Tan WS, Wong M, Cima I, Tan MH, Wee LJK, Hillmer AM, Tan IB, Robson P, Prabhakar S.

Nat Genet. 2018 Dec;50(12):1754. doi: 10.1038/s41588-018-0299-1.

PMID:
30420650
22.

Regulating transcriptional activity by phosphorylation: A new mechanism for the ARX homeodomain transcription factor.

Mattiske T, Tan MH, Dearsley O, Cloosterman D, Hii CS, Gécz J, Shoubridge C.

PLoS One. 2018 Nov 12;13(11):e0206914. doi: 10.1371/journal.pone.0206914. eCollection 2018.

23.

Pre-operative pressure pain thresholds do not meaningfully explain satisfaction or improvement in pain after knee replacement: a cohort study.

Leung YY, Lim Z, Fan Q, Wylde V, Xiong S, Yeo SJ, Lo NN, Chong HC, Yeo W, Tan MH, Chakraborty B, Bak-Siew Wong S, Thumboo J.

Osteoarthritis Cartilage. 2019 Jan;27(1):49-58. doi: 10.1016/j.joca.2018.09.003. Epub 2018 Sep 19.

24.

Association between the effect of controlled fluid resuscitation on massive hemorrhage and expression of human neutrophil lipocalin.

Yu JY, Peng JH, Hui L, Huang HQ, Tan MH, Jian G.

Exp Ther Med. 2018 Oct;16(4):3534-3538. doi: 10.3892/etm.2018.6591. Epub 2018 Aug 9.

25.

Association between preoperative anaemia and blood transfusion with long-term functional and quality of life outcomes amongst patients undergoing primary total knee arthroplasty in Singapore: a single-centre retrospective study.

Abdullah HR, Ranjakunalan N, Yeo W, Tan MH, Poopalalingam R, Sim YE.

Qual Life Res. 2019 Jan;28(1):85-98. doi: 10.1007/s11136-018-1996-z. Epub 2018 Sep 10.

PMID:
30203301
26.

Biological significance and prognostic relevance of peripheral blood neutrophil-to-lymphocyte ratio in soft tissue sarcoma.

Chan JY, Zhang Z, Chew W, Tan GF, Lim CL, Zhou L, Goh WL, Poon E, Somasundaram N, Selvarajan S, Sittampalam K, Chin F, Teh J, Tan MH, Soo KC, Teo M, Farid M, Quek R.

Sci Rep. 2018 Aug 10;8(1):11959. doi: 10.1038/s41598-018-30442-5.

27.

The journey continues in Clinical Diabetes and Endocrinology.

Barkan A, Gianchandani R, Tan MH.

Clin Diabetes Endocrinol. 2018 Jul 31;4:17. doi: 10.1186/s40842-018-0067-2. eCollection 2018. No abstract available.

28.

Sacral chordoma: clinical experience of a series of 11 patients over 18 years.

Lim JBT, Soeharno H, Tan MH.

Eur J Orthop Surg Traumatol. 2019 Jan;29(1):9-15. doi: 10.1007/s00590-018-2284-x. Epub 2018 Jul 31.

PMID:
30066091
29.

Gap difference in navigated TKA: a measure of the imbalanced flexion-extension gap.

Chia ZY, Pang HN, Tan MH, Yeo SJ.

SICOT J. 2018;4:30. doi: 10.1051/sicotj/2018007. Epub 2018 Jul 13.

30.

SRSF9 selectively represses ADAR2-mediated editing of brain-specific sites in primates.

Shanmugam R, Zhang F, Srinivasan H, Charles Richard JL, Liu KI, Zhang X, Woo CWA, Chua ZHM, Buschdorf JP, Meaney MJ, Tan MH.

Nucleic Acids Res. 2018 Aug 21;46(14):7379-7395. doi: 10.1093/nar/gky615.

31.

Appropriateness of vancomycin therapeutic drug monitoring and its outcomes among non-dialysis patients in a tertiary hospital in Singapore.

Seng JJB, Yong MHA, Peh ZX, Soong JL, Tan MH.

Int J Clin Pharm. 2018 Oct;40(5):977-981. doi: 10.1007/s11096-018-0670-4. Epub 2018 Jun 12.

PMID:
29948742
32.

LIM kinase1 regulates mitotic centrosome integrity via its activity on dynein light intermediate chains.

Ou S, Tan MH, Weng T, Li H, Koh CG.

Open Biol. 2018 Jun;8(6). pii: 170202. doi: 10.1098/rsob.170202.

33.

Systematic evaluation of CRISPR-Cas systems reveals design principles for genome editing in human cells.

Wang Y, Liu KI, Sutrisnoh NB, Srinivasan H, Zhang J, Li J, Zhang F, Lalith CRJ, Xing H, Shanmugam R, Foo JN, Yeo HT, Ooi KH, Bleckwehl T, Par YYR, Lee SM, Ismail NNB, Sanwari NAB, Lee STV, Lew J, Tan MH.

Genome Biol. 2018 May 29;19(1):62. doi: 10.1186/s13059-018-1445-x.

34.

Aspergoterpenins A⁻D: Four New Antimicrobial Bisabolane Sesquiterpenoid Derivatives from an Endophytic Fungus Aspergillus versicolor.

Guo ZY, Tan MH, Liu CX, Lv MM, Deng ZS, Cao F, Zou K, Proksch P.

Molecules. 2018 May 28;23(6). pii: E1291. doi: 10.3390/molecules23061291.

35.

ORDER within the chaos: Insights into phylogenetic relationships within the Anomura (Crustacea: Decapoda) from mitochondrial sequences and gene order rearrangements.

Tan MH, Gan HM, Lee YP, Linton S, Grandjean F, Bartholomei-Santos ML, Miller AD, Austin CM.

Mol Phylogenet Evol. 2018 Oct;127:320-331. doi: 10.1016/j.ympev.2018.05.015. Epub 2018 May 23.

PMID:
29800651
36.
37.

Rapid Control of Genome Editing in Human Cells by Chemical-Inducible CRISPR-Cas Systems.

Liu KI, Ramli MNB, Sutrisnoh NB, Tan MH.

Methods Mol Biol. 2018;1772:267-288. doi: 10.1007/978-1-4939-7795-6_15.

PMID:
29754234
38.

World Cancer Day.

Tan MH.

Ann Acad Med Singapore. 2018 Mar;47(3):88-89. No abstract available.

39.

Evaluation of three polygenic risk score models for the prediction of breast cancer risk in Singapore Chinese.

Chan CHT, Munusamy P, Loke SY, Koh GL, Yang AZY, Law HY, Yoon CS, Wong CY, Yong WS, Wong NS, Ng RCH, Ong KW, Madhukumar P, Oey CL, Ho GH, Tan PH, Tan MH, Ang P, Yap YS, Lee ASG.

Oncotarget. 2018 Jan 31;9(16):12796-12804. doi: 10.18632/oncotarget.24374. eCollection 2018 Feb 27.

40.

Size-Based Enrichment Technologies for Non-cancerous Tumor-Derived Cells in Blood.

Mong J, Tan MH.

Trends Biotechnol. 2018 May;36(5):511-522. doi: 10.1016/j.tibtech.2018.02.010. Epub 2018 Mar 17. Review.

PMID:
29559166
41.

Laboratory and Benchtop Performance of a Mealtime Insulin-Delivery System.

Dreon DM, Hannon TM, Cross B, Carter BJ, Mercer NS, Nguyen JH, Tran A, Melendez PA, Morales N, Nelson JE, Tan MH.

J Diabetes Sci Technol. 2018 Jul;12(4):817-827. doi: 10.1177/1932296818760633. Epub 2018 Feb 28.

42.

Colchicine lack of effectiveness in symptom and inflammation modification in knee osteoarthritis (COLKOA): a randomized controlled trial.

Leung YY, Haaland B, Huebner JL, Wong SBS, Tjai M, Wang C, Chowbay B, Thumboo J, Chakraborty B, Tan MH, Kraus VB.

Osteoarthritis Cartilage. 2018 May;26(5):631-640. doi: 10.1016/j.joca.2018.01.026. Epub 2018 Feb 7.

43.

Determinants of breast size in Asian women.

Lim LY, Ho PJ, Liu J, Chay WY, Tan MH, Hartman M, Li J.

Sci Rep. 2018 Jan 19;8(1):1201. doi: 10.1038/s41598-018-19437-4.

44.

Finding Nemo: hybrid assembly with Oxford Nanopore and Illumina reads greatly improves the clownfish (Amphiprion ocellaris) genome assembly.

Tan MH, Austin CM, Hammer MP, Lee YP, Croft LJ, Gan HM.

Gigascience. 2018 Mar 1;7(3):1-6. doi: 10.1093/gigascience/gix137.

45.

Patient Perceptions and Preferences for a Mealtime Insulin Delivery Patch.

Peyrot M, Dreon D, Zraick V, Cross B, Tan MH.

Diabetes Ther. 2018 Feb;9(1):297-307. doi: 10.1007/s13300-017-0365-1. Epub 2018 Jan 11.

46.

Gene Therapy for Bone Repair Using Human Cells: Superior Osteogenic Potential of Bone Morphogenetic Protein 2-Transduced Mesenchymal Stem Cells Derived from Adipose Tissue Compared to Bone Marrow.

Bougioukli S, Sugiyama O, Pannell W, Ortega B, Tan MH, Tang AH, Yoho R, Oakes DA, Lieberman JR.

Hum Gene Ther. 2018 Apr;29(4):507-519. doi: 10.1089/hum.2017.097. Epub 2018 Mar 14.

47.

An Atypical Localized Form of Hidradenitis Suppurativa of the Jawline and Neck Mimicking Severe Cystic Acne on Presentation.

Castrillón Velásquez MA, Kim M, Tan MH, Tran K, Murrell DF.

Skin Appendage Disord. 2017 Oct;3(4):215-218. doi: 10.1159/000477412. Epub 2017 Jun 14.

48.
49.

Treatment and outcomes of melanoma in Asia: Results from the National Cancer Centre Singapore.

Teh YL, Goh WL, Tan SH, Yong G, Sairi ANH, Soo KC, Ong J, Chia C, Tan G, Soeharno H, Tan MH, Chan M, Sathiyamoorthy S, Sittampalam K, Teh J, Chin F, Sethi V, Teo M, Quek R, Farid M.

Asia Pac J Clin Oncol. 2018 Apr;14(2):e95-e102. doi: 10.1111/ajco.12802. Epub 2017 Oct 20.

PMID:
29052960
50.

Dynamic landscape and regulation of RNA editing in mammals.

Tan MH, Li Q, Shanmugam R, Piskol R, Kohler J, Young AN, Liu KI, Zhang R, Ramaswami G, Ariyoshi K, Gupte A, Keegan LP, George CX, Ramu A, Huang N, Pollina EA, Leeman DS, Rustighi A, Goh YPS; GTEx Consortium; Laboratory, Data Analysis &Coordinating Center (LDACC)—Analysis Working Group; Statistical Methods groups—Analysis Working Group; Enhancing GTEx (eGTEx) groups; NIH Common Fund; NIH/NCI; NIH/NHGRI; NIH/NIMH; NIH/NIDA; Biospecimen Collection Source Site—NDRI; Biospecimen Collection Source Site—RPCI; Biospecimen Core Resource—VARI; Brain Bank Repository—University of Miami Brain Endowment Bank; Leidos Biomedical—Project Management; ELSI Study; Genome Browser Data Integration &Visualization—EBI; Genome Browser Data Integration &Visualization—UCSC Genomics Institute, University of California Santa Cruz, Chawla A, Del Sal G, Peltz G, Brunet A, Conrad DF, Samuel CE, O'Connell MA, Walkley CR, Nishikura K, Li JB.

Nature. 2017 Oct 11;550(7675):249-254. doi: 10.1038/nature24041.

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