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AQP5 enriches for stem cells and cancer origins in the distal stomach.

Tan SH, Swathi Y, Tan S, Goh J, Seishima R, Murakami K, Oshima M, Tsuji T, Phuah P, Tan LT, Wong E, Fatehullah A, Sheng T, Ho SWT, Grabsch HI, Srivastava S, Teh M, Denil SLIJ, Mustafah S, Tan P, Shabbir A, So J, Yeoh KG, Barker N.

Nature. 2020 Feb;578(7795):437-443. doi: 10.1038/s41586-020-1973-x. Epub 2020 Feb 5.


Proximal Tibial Stress Fractures: A Diagnostic Challenge.

Wu C, Ho SW, Tan LT.

Ann Acad Med Singapore. 2019 Oct;48(10):338-340. No abstract available.


Cardiac manifestations and gene mutations of patients with RASopathies in Taiwan.

Lee CL, Tan LTH, Lin HY, Hwu WL, Lee NC, Chien YH, Chuang CK, Wu MH, Wang JK, Chu SY, Lin JL, Lo FS, Su PH, Hsu CC, Ko YY, Chen MR, Chiu HC, Lin SP.

Am J Med Genet A. 2020 Feb;182(2):357-364. doi: 10.1002/ajmg.a.61429. Epub 2019 Dec 14.


Epinecidin-1, an Antimicrobial Peptide Derived From Grouper (Epinephelus coioides): Pharmacological Activities and Applications.

Chee PY, Mang M, Lau ES, Tan LT, He YW, Lee WL, Pusparajah P, Chan KG, Lee LH, Goh BH.

Front Microbiol. 2019 Nov 20;10:2631. doi: 10.3389/fmicb.2019.02631. eCollection 2019. Review.


Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development.

Seishima R, Leung C, Yada S, Murad KBA, Tan LT, Hajamohideen A, Tan SH, Itoh H, Murakami K, Ishida Y, Nakamizo S, Yoshikawa Y, Wong E, Barker N.

Nat Commun. 2019 Nov 26;10(1):5378. doi: 10.1038/s41467-019-13363-3.


Trikoramide A, a Prenylated Cyanobactin from the Marine Cyanobacterium Symploca hydnoides.

Phyo MY, Ding CYG, Goh HC, Goh JX, Ong JFM, Chan SH, Yung PYM, Candra H, Tan LT.

J Nat Prod. 2019 Dec 27;82(12):3482-3488. doi: 10.1021/acs.jnatprod.9b00675. Epub 2019 Nov 25.


Overexpression of oxyR Increases Phenazine-1-Carboxylic Acid Biosynthesis via Small RNA phrS in the Rhizobacterium Strain Pseudomonas PA1201.

Sun S, Tan LT, Fang YL, Jin ZJ, Zhou L, Goh BH, Lee LH, Zhou J, He YW.

Mol Plant Microbe Interact. 2020 Mar;33(3):488-498. doi: 10.1094/MPMI-09-19-0264-R. Epub 2020 Jan 7.


Streptomyces sp. MUM256: A Source for Apoptosis Inducing and Cell Cycle-Arresting Bioactive Compounds against Colon Cancer Cells.

Tan LT, Chan CK, Chan KG, Pusparajah P, Khan TM, Ser HL, Lee LH, Goh BH.

Cancers (Basel). 2019 Nov 6;11(11). pii: E1742. doi: 10.3390/cancers11111742.


Effect of (R)-salbutamol on the switch of phenotype and metabolic pattern in LPS-induced macrophage cells.

Wang S, Liu F, Tan KS, Ser HL, Tan LT, Lee LH, Tan W.

J Cell Mol Med. 2020 Jan;24(1):722-736. doi: 10.1111/jcmm.14780. Epub 2019 Nov 3.


Draft Genome Sequence of Mycolicibacterium sp. Strain 018/SC-01/001, Isolated from the Marine Sponge Iotrochota sp.

Ong JFM, Tan LT.

Microbiol Resour Announc. 2019 Oct 17;8(42). pii: e01019-19. doi: 10.1128/MRA.01019-19.


[The cell cycle pathway regulates chicken abdominal fat deposition as revealed by transcriptome sequencing].

Chen JH, Ren XY, Li LM, Lu SY, Cheng T, Tan LT, Liang SD, He DL, Luo QB, Nie QH, Zhang XQ, Luo W.

Yi Chuan. 2019 Oct 20;41(10):962-973. doi: 10.16288/j.yczz.19-098. Chinese.


Draft Genome Sequence of Bacillus sp. Strain 007/AIA-02/001, Isolated from the Marine Sponge Coelocarteria singaporensis.

Ong JFM, Goh HC, Tan LT.

Microbiol Resour Announc. 2019 Aug 29;8(35). pii: e00389-19. doi: 10.1128/MRA.00389-19.


Safety and Efficacy of Pneumococcal Vaccination in Pediatric Nephrotic Syndrome.

Goonewardene ST, Tang C, Tan LT, Chan KG, Lingham P, Lee LH, Goh BH, Pusparajah P.

Front Pediatr. 2019 Aug 13;7:339. doi: 10.3389/fped.2019.00339. eCollection 2019. Review.


Formononetin: A Review of Its Anticancer Potentials and Mechanisms.

Tay KC, Tan LT, Chan CK, Hong SL, Chan KG, Yap WH, Pusparajah P, Lee LH, Goh BH.

Front Pharmacol. 2019 Jul 26;10:820. doi: 10.3389/fphar.2019.00820. eCollection 2019. Review.


Clinical Outcome of Exclusively Radiographer-led Delivery of Postoperative Vaginal Vault Brachytherapy for Endometrial Cancer - The Addenbrooke's Experience.

Buckley H, Bradshaw K, Gregory D, Prewett S, Tan LT.

Clin Oncol (R Coll Radiol). 2019 Dec;31(12):844-849. doi: 10.1016/j.clon.2019.06.018. Epub 2019 Jul 13.


Nobiletin and Derivatives: Functional Compounds from Citrus Fruit Peel for Colon Cancer Chemoprevention.

Goh JXH, Tan LT, Goh JK, Chan KG, Pusparajah P, Lee LH, Goh BH.

Cancers (Basel). 2019 Jun 21;11(6). pii: E867. doi: 10.3390/cancers11060867. Review.


Streptomyces sp. MUM273b: A mangrove-derived potential source for antioxidant and UVB radiation protectants.

Tan LT, Mahendra CK, Yow YY, Chan KG, Khan TM, Lee LH, Goh BH.

Microbiologyopen. 2019 Oct;8(10):e859. doi: 10.1002/mbo3.859. Epub 2019 Jun 14.


Change in Patterns of Failure After Image-Guided Brachytherapy for Cervical Cancer: Analysis From the RetroEMBRACE Study.

Tan LT, Pötter R, Sturdza A, Fokdal L, Haie-Meder C, Schmid M, Gregory D, Petric P, Jürgenliemk-Schulz I, Gillham C, Van Limbergen E, Hoskin P, Tharavichitkul E, Villafranca E, Mahantshetty U, Kirisits C, Lindegaard J, Kirchheiner K, Tanderup K.

Int J Radiat Oncol Biol Phys. 2019 Jul 15;104(4):895-902. doi: 10.1016/j.ijrobp.2019.03.038. Epub 2019 Mar 30.


Importance of training in external beam treatment planning for locally advanced cervix cancer: Report from the EMBRACE II dummy run.

Seppenwoolde Y, Assenholt MS, Georg D, Nout R, Tan LT, Rumpold T, de Leeuw A, Jürgenliemk-Schulz I, Kirisits C, Pötter R, Lindegaard JC, Tanderup K; EMBRACE Collaborative Group.

Radiother Oncol. 2019 Apr;133:149-155. doi: 10.1016/j.radonc.2019.01.012. Epub 2019 Jan 28.


Importance of Technique, Target Selection, Contouring, Dose Prescription, and Dose-Planning in External Beam Radiation Therapy for Cervical Cancer: Evolution of Practice From EMBRACE-I to II.

Berger T, Seppenwoolde Y, Pötter R, Assenholt MS, Lindegaard JC, Nout RA, de Leeuw A, Jürgenliemk-Schulz I, Tan LT, Georg D, Kirisits C, Dumas I, Nesvacil N, Swamidas J, Hudej R, Lowe G, Hellebust TP, Menon G, Fokdal L, Tanderup K; EMBRACE Collaborative Group.

Int J Radiat Oncol Biol Phys. 2019 Jul 15;104(4):885-894. doi: 10.1016/j.ijrobp.2019.03.020. Epub 2019 Mar 21.


Symptoms, Sites, and Significance of Mycoplasma genitalium in Men Who Have Sex with Men.

Read TRH, Murray GL, Danielewski JA, Fairley CK, Doyle M, Worthington K, Su J, Mokany E, Tan LT, Lee D, Vodstrcil LA, Chow EPF, Garland SM, Chen MY, Bradshaw CS.

Emerg Infect Dis. 2019 Apr;25(4):719-727. doi: 10.3201/eid2504.181258.


Mangrove derived Streptomyces sp. MUM265 as a potential source of antioxidant and anticolon-cancer agents.

Tan LT, Chan KG, Pusparajah P, Yin WF, Khan TM, Lee LH, Goh BH.

BMC Microbiol. 2019 Feb 13;19(1):38. doi: 10.1186/s12866-019-1409-7.


Integrated Genomic and Metabolomic Approach to the Discovery of Potential Anti-Quorum Sensing Natural Products from Microbes Associated with Marine Samples from Singapore.

Ong JFM, Goh HC, Lim SC, Pang LM, Chin JSF, Tan KS, Liang ZX, Yang L, Glukhov E, Gerwick WH, Tan LT.

Mar Drugs. 2019 Jan 21;17(1). pii: E72. doi: 10.3390/md17010072.


Magnetic cellulose nanocrystal stabilized Pickering emulsions for enhanced bioactive release and human colon cancer therapy.

Low LE, Tan LT, Goh BH, Tey BT, Ong BH, Tang SY.

Int J Biol Macromol. 2019 Apr 15;127:76-84. doi: 10.1016/j.ijbiomac.2019.01.037. Epub 2019 Jan 9.


A type III effector XopLXcc8004 is vital for Xanthomonas campestris pathovar campestris to regulate plant immunity.

Yan X, Tao J, Luo HL, Tan LT, Rong W, Li HP, He CZ.

Res Microbiol. 2019 Apr - May;170(3):138-146. doi: 10.1016/j.resmic.2018.12.001. Epub 2018 Dec 27.


MS/MS-Based Molecular Networking Approach for the Detection of Aplysiatoxin-Related Compounds in Environmental Marine Cyanobacteria.

Ding CYG, Pang LM, Liang ZX, Goh KKK, Glukhov E, Gerwick WH, Tan LT.

Mar Drugs. 2018 Dec 13;16(12). pii: E505. doi: 10.3390/md16120505.


Risk Factors for Ureteral Stricture After Radiochemotherapy Including Image Guided Adaptive Brachytherapy in Cervical Cancer: Results From the EMBRACE Studies.

Fokdal L, Tanderup K, Pötter R, Sturdza A, Kirchheiner K, Chargari C, Jürgenliemk-Schulz IM, Segedin B, Tan LT, Hoskin P, Mahantshetty U, Bruheim K, Rai B, Kirisits C, Lindegaard JC; EMBRACE Collaborative Group.

Int J Radiat Oncol Biol Phys. 2019 Mar 15;103(4):887-894. doi: 10.1016/j.ijrobp.2018.11.006. Epub 2018 Nov 10.


Benderamide A, a Cyclic Depsipeptide from a Singapore Collection of Marine Cyanobacterium cf. Lyngbya sp.

Ding CYG, Ong JFM, Goh HC, Coffill CR, Tan LT.

Mar Drugs. 2018 Oct 26;16(11). pii: E409. doi: 10.3390/md16110409.


Streptomyces as a Prominent Resource of Future Anti-MRSA Drugs.

Kemung HM, Tan LT, Khan TM, Chan KG, Pusparajah P, Goh BH, Lee LH.

Front Microbiol. 2018 Sep 24;9:2221. doi: 10.3389/fmicb.2018.02221. eCollection 2018. Review.


Biosorption of copper by endophytic fungi isolated from Nepenthes ampullaria.

Wong C, Tan LT, Mujahid A, Lihan S, Wee JLS, Ting LF, Müller M.

Lett Appl Microbiol. 2018 Oct;67(4):384-391. doi: 10.1111/lam.13049. Epub 2018 Aug 22.


Efficacy and Safety of Cyclosporine in Acute Myocardial Infarction: A Systematic Review and Meta-Analysis.

Rahman FA, Abdullah SS, Manan WZWA, Tan LT, Neoh CF, Ming LC, Chan KG, Lee LH, Goh BH, Salmasi S, Wu DB, Khan TM.

Front Pharmacol. 2018 Jun 19;9:238. doi: 10.3389/fphar.2018.00238. eCollection 2018. Review.


Antioxidative Potential of a Streptomyces sp. MUM292 Isolated from Mangrove Soil.

Tan LT, Chan KG, Chan CK, Khan TM, Lee LH, Goh BH.

Biomed Res Int. 2018 Apr 1;2018:4823126. doi: 10.1155/2018/4823126. eCollection 2018.


Image-guided Adaptive Brachytherapy for Cervix Cancer - A Story of Successful Collaboration within the GEC-ESTRO GYN Network and the EMBRACE Studies.

Tan LT, Tanderup K, Hoskin P, Cooper R, Pötter R.

Clin Oncol (R Coll Radiol). 2018 Jul;30(7):397-399. doi: 10.1016/j.clon.2018.04.005. Epub 2018 May 3. No abstract available.


The EMBRACE II study: The outcome and prospect of two decades of evolution within the GEC-ESTRO GYN working group and the EMBRACE studies.

Pötter R, Tanderup K, Kirisits C, de Leeuw A, Kirchheiner K, Nout R, Tan LT, Haie-Meder C, Mahantshetty U, Segedin B, Hoskin P, Bruheim K, Rai B, Huang F, Van Limbergen E, Schmid M, Nesvacil N, Sturdza A, Fokdal L, Jensen NBK, Georg D, Assenholt M, Seppenwoolde Y, Nomden C, Fortin I, Chopra S, van der Heide U, Rumpold T, Lindegaard JC, Jürgenliemk-Schulz I; EMBRACE Collaborative Group.

Clin Transl Radiat Oncol. 2018 Jan 11;9:48-60. doi: 10.1016/j.ctro.2018.01.001. eCollection 2018 Feb. Review.


Resveratrol-Potential Antibacterial Agent against Foodborne Pathogens.

Ma DSL, Tan LT, Chan KG, Yap WH, Pusparajah P, Chuah LH, Ming LC, Khan TM, Lee LH, Goh BH.

Front Pharmacol. 2018 Feb 19;9:102. doi: 10.3389/fphar.2018.00102. eCollection 2018. Review.


Novel use of a balloon dilatation catheter to enable mechanical lithotripsy of difficult common bile duct stones after initial failed attempt: A case report.

Loh WL, Tung JYM, Tan THY, Tan LT, Tan S, Ngoi SS.

Int J Surg Case Rep. 2018;43:9-12. doi: 10.1016/j.ijscr.2018.01.005. Epub 2018 Jan 28.


[Evaluation and treatment of children's laryngeal clefts].

Chen C, Tan LT, Xu ZM.

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2018 Jan 7;53(1):9-15. doi: 10.3760/cma.j.issn.1673-0860.2018.01.003. Chinese.


Focused Review: Cytotoxic and Antioxidant Potentials of Mangrove-Derived Streptomyces.

Ser HL, Tan LT, Law JW, Chan KG, Duangjai A, Saokaew S, Pusparajah P, Ab Mutalib NS, Khan TM, Goh BH, Lee LH.

Front Microbiol. 2017 Nov 1;8:2065. doi: 10.3389/fmicb.2017.02065. eCollection 2017. Review.


Challenges for Quality Assurance of Target Volume Delineation in Clinical Trials.

Chang ATY, Tan LT, Duke S, Ng WT.

Front Oncol. 2017 Sep 25;7:221. doi: 10.3389/fonc.2017.00221. eCollection 2017. Review.


Dental extractions for preradiation dental clearance and incidence of osteoradionecrosis in patients with nasopharyngeal carcinoma treated with intensity-modulated radiotherapy.

See Toh YL, Soong YL, Chim YX, Tan LT, Lye WK, Teoh KH.

J Investig Clin Dent. 2018 May;9(2):e12295. doi: 10.1111/jicd.12295. Epub 2017 Sep 1.


Anti-neuroinflammatory Activity of Elephantopus scaber L. via Activation of Nrf2/HO-1 Signaling and Inhibition of p38 MAPK Pathway in LPS-Induced Microglia BV-2 Cells.

Chan CK, Tan LT, Andy SN, Kamarudin MNA, Goh BH, Kadir HA.

Front Pharmacol. 2017 Jun 21;8:397. doi: 10.3389/fphar.2017.00397. eCollection 2017.


Ectopic orbital meningioma: Fact or fiction?

Tan LT, Stewart CM, Sheerin F, MacDonald B, Silva P, Norris JH.

Orbit. 2017 Jun;36(3):144-146. doi: 10.1080/01676830.2017.1279663. Epub 2017 Mar 3.


Lgr5-expressing chief cells drive epithelial regeneration and cancer in the oxyntic stomach.

Leushacke M, Tan SH, Wong A, Swathi Y, Hajamohideen A, Tan LT, Goh J, Wong E, Denil SLIJ, Murakami K, Barker N.

Nat Cell Biol. 2017 Jul;19(7):774-786. doi: 10.1038/ncb3541. Epub 2017 Jun 5.


Streptomyces sp. MUM212 as a Source of Antioxidants with Radical Scavenging and Metal Chelating Properties.

Tan LT, Chan KG, Khan TM, Bukhari SI, Saokaew S, Duangjai A, Pusparajah P, Lee LH, Goh BH.

Front Pharmacol. 2017 May 17;8:276. doi: 10.3389/fphar.2017.00276. eCollection 2017.


Trigonometry-Integrated 'Lift' Technique (TILT) for Restoring Volar Tilt in Distal Radius Fractures: Description of Technique and Preliminary Results.

Sechachalam S, Satku M, Wong JH, Tan LT, Yong FC.

J Hand Surg Asian Pac Vol. 2017 Mar;22(1):53-58. doi: 10.1142/S0218810417500095.


Targeting Membrane Lipid a Potential Cancer Cure?

Tan LT, Chan KG, Pusparajah P, Lee WL, Chuah LH, Khan TM, Lee LH, Goh BH.

Front Pharmacol. 2017 Jan 23;8:12. doi: 10.3389/fphar.2017.00012. eCollection 2017.


The Effectiveness and Safety of Topical Capsaicin in Postherpetic Neuralgia: A Systematic Review and Meta-analysis.

Yong YL, Tan LT, Ming LC, Chan KG, Lee LH, Goh BH, Khan TM.

Front Pharmacol. 2017 Jan 10;7:538. doi: 10.3389/fphar.2016.00538. eCollection 2016. Review.


Golden Needle Mushroom: A Culinary Medicine with Evidenced-Based Biological Activities and Health Promoting Properties.

Tang C, Hoo PC, Tan LT, Pusparajah P, Khan TM, Lee LH, Goh BH, Chan KG.

Front Pharmacol. 2016 Dec 7;7:474. doi: 10.3389/fphar.2016.00474. eCollection 2016. Review.


Streptomyces antioxidans sp. nov., a Novel Mangrove Soil Actinobacterium with Antioxidative and Neuroprotective Potentials.

Ser HL, Tan LT, Palanisamy UD, Abd Malek SN, Yin WF, Chan KG, Goh BH, Lee LH.

Front Microbiol. 2016 Jun 16;7:899. doi: 10.3389/fmicb.2016.00899. eCollection 2016.


Key Issues When Reconstructing Extensive Upper Eyelid Defects With Description of a Dynamic, Frontalis Turnover Flap.

Stewart CM, Tan LT, Johnson D, Norris JH.

Ophthalmic Plast Reconstr Surg. 2016 Jul-Aug;32(4):249-51. doi: 10.1097/IOP.0000000000000721. Review.


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