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Items: 1 to 50 of 81

1.

EZH2 promotes neoplastic transformation through VAV interaction-dependent extranuclear mechanisms.

Venkatesan N, Wong JF, Tan KP, Chung HH, Yau YH, Cukuroglu E, Allahverdi A, Nordenskiöld L, Göke J, Geifman-Shochat S, Lin VCL, Madhusudhan MS, Su IH.

Oncogene. 2018 Jan 25;37(4):461-477. doi: 10.1038/onc.2017.309. Epub 2017 Oct 2.

PMID:
28967906
2.

Use of Human Pluripotent Stem Cell Derived-Cardiomyocytes to Study Drug-Induced Cardiotoxicity.

Maillet A, Tan KP, Brunham LR.

Curr Protoc Toxicol. 2017 Aug 4;73:22.5.1-22.5.22. doi: 10.1002/cptx.30.

PMID:
28777443
3.

Depth dependent amino acid substitution matrices and their use in predicting deleterious mutations.

Farheen N, Sen N, Nair S, Tan KP, Madhusudhan MS.

Prog Biophys Mol Biol. 2017 Sep;128:14-23. doi: 10.1016/j.pbiomolbio.2017.02.004. Epub 2017 Feb 15.

PMID:
28212855
4.

Fucosylation of LAMP-1 and LAMP-2 by FUT1 correlates with lysosomal positioning and autophagic flux of breast cancer cells.

Tan KP, Ho MY, Cho HC, Yu J, Hung JT, Yu AL.

Cell Death Dis. 2016 Aug 25;7(8):e2347. doi: 10.1038/cddis.2016.243.

5.

Identification, synthesis and evaluation of SARS-CoV and MERS-CoV 3C-like protease inhibitors.

Kumar V, Tan KP, Wang YM, Lin SW, Liang PH.

Bioorg Med Chem. 2016 Jul 1;24(13):3035-3042. doi: 10.1016/j.bmc.2016.05.013. Epub 2016 May 12.

PMID:
27240464
6.

Advancing Understanding of Acculturation for Adolescents of Asian Immigrants: Person-Oriented Analysis of Acculturation Strategy Among Korean American Youth.

Choi Y, Tan KP, Yasui M, Hahm HC.

J Youth Adolesc. 2016 Jul;45(7):1380-95. doi: 10.1007/s10964-016-0496-0. Epub 2016 May 4.

7.

Dynamic change in natural killer cell type in the human ocular mucosa in situ as means of immune evasion by adenovirus infection.

Yawata N, Selva KJ, Liu YC, Tan KP, Lee AW, Siak J, Lan W, Vania M, Arundhati A, Tong L, Li J, Mehta JS, Yawata M.

Mucosal Immunol. 2016 Jan;9(1):159-70. doi: 10.1038/mi.2015.47. Epub 2015 Jun 17.

PMID:
26080707
8.

The comparative accuracy of ultrasound and mammography in the detection of breast cancer.

Tan KP, Mohamad Azlan Z, Rumaisa MP, Siti Aisyah Murni MR, Radhika S, Nurismah MI, Norlia A, Zulfiqar MA.

Med J Malaysia. 2014 Apr;69(2):79-85.

9.

Identification, synthesis, and evaluation of new neuraminidase inhibitors.

Kumar V, Chang CK, Tan KP, Jung YS, Chen SH, Cheng YS, Liang PH.

Org Lett. 2014 Oct 3;16(19):5060-3. doi: 10.1021/ol502410x. Epub 2014 Sep 17.

PMID:
25229881
10.

TSpred: a web server for the rational design of temperature-sensitive mutants.

Tan KP, Khare S, Varadarajan R, Madhusudhan MS.

Nucleic Acids Res. 2014 Jul;42(Web Server issue):W277-84. doi: 10.1093/nar/gku319. Epub 2014 Apr 29.

11.
12.

Gene selection for cancer identification: a decision tree model empowered by particle swarm optimization algorithm.

Chen KH, Wang KJ, Tsai ML, Wang KM, Adrian AM, Cheng WC, Yang TS, Teng NC, Tan KP, Chang KS.

BMC Bioinformatics. 2014 Feb 20;15:49. doi: 10.1186/1471-2105-15-49.

13.

Comparative effects of plant growth regulators on leaf and stem explants of Labisia pumila var. alata.

Ling AP, Tan KP, Hussein S.

J Zhejiang Univ Sci B. 2013 Jul;14(7):621-31. doi: 10.1631/jzus.B1200135.

14.
15.

Depth: a web server to compute depth, cavity sizes, detect potential small-molecule ligand-binding cavities and predict the pKa of ionizable residues in proteins.

Tan KP, Nguyen TB, Patel S, Varadarajan R, Madhusudhan MS.

Nucleic Acids Res. 2013 Jul;41(Web Server issue):W314-21. doi: 10.1093/nar/gkt503. Epub 2013 Jun 12.

16.

In vivo biocompatibility of two PEG/PAA interpenetrating polymer networks as corneal inlays following deep stromal pocket implantation.

Tan XW, Hartman L, Tan KP, Poh R, Myung D, Zheng LL, Waters D, Noolandi J, Beuerman RW, Frank CW, Ta CN, Tan DT, Mehta JS.

J Mater Sci Mater Med. 2013 Apr;24(4):967-77. doi: 10.1007/s10856-012-4848-3. Epub 2013 Jan 26.

17.

Recent development of 3C and 3CL protease inhibitors for anti-coronavirus and anti-picornavirus drug discovery.

Ramajayam R, Tan KP, Liang PH.

Biochem Soc Trans. 2011 Oct;39(5):1371-5. doi: 10.1042/BST0391371. Review.

PMID:
21936817
18.

CLICK--topology-independent comparison of biomolecular 3D structures.

Nguyen MN, Tan KP, Madhusudhan MS.

Nucleic Acids Res. 2011 Jul;39(Web Server issue):W24-8. doi: 10.1093/nar/gkr393. Epub 2011 May 20.

19.

DEPTH: a web server to compute depth and predict small-molecule binding cavities in proteins.

Tan KP, Varadarajan R, Madhusudhan MS.

Nucleic Acids Res. 2011 Jul;39(Web Server issue):W242-8. doi: 10.1093/nar/gkr356. Epub 2011 May 16.

20.

Hypertension in a residential home for the elderly in Penang, Malaysia.

Ong HT, Oung LS, Ong LM, Tan KP.

Med J Malaysia. 2010 Mar;65(1):18-20.

21.

Participation of nuclear factor (erythroid 2-related), factor 2 in ameliorating lithocholic acid-induced cholestatic liver injury in mice.

Tan KP, Wood GA, Yang M, Ito S.

Br J Pharmacol. 2010 Nov;161(5):1111-21. doi: 10.1111/j.1476-5381.2010.00953.x.

22.

Synthesis and evaluation of pyrazolone compounds as SARS-coronavirus 3C-like protease inhibitors.

Ramajayam R, Tan KP, Liu HG, Liang PH.

Bioorg Med Chem. 2010 Nov 15;18(22):7849-54. doi: 10.1016/j.bmc.2010.09.050. Epub 2010 Sep 25.

PMID:
20947359
23.

Synthesis, docking studies, and evaluation of pyrimidines as inhibitors of SARS-CoV 3CL protease.

Ramajayam R, Tan KP, Liu HG, Liang PH.

Bioorg Med Chem Lett. 2010 Jun 15;20(12):3569-72. doi: 10.1016/j.bmcl.2010.04.118. Epub 2010 May 20.

PMID:
20494577
24.

Aryl hydrocarbon receptor is a transcriptional activator of the human breast cancer resistance protein (BCRP/ABCG2).

Tan KP, Wang B, Yang M, Boutros PC, Macaulay J, Xu H, Chuang AI, Kosuge K, Yamamoto M, Takahashi S, Wu AM, Ross DD, Harper PA, Ito S.

Mol Pharmacol. 2010 Aug;78(2):175-85. doi: 10.1124/mol.110.065078. Epub 2010 May 11.

25.
26.

NRF2 as a determinant of cellular resistance in retinoic acid cytotoxicity.

Tan KP, Kosuge K, Yang M, Ito S.

Free Radic Biol Med. 2008 Dec 15;45(12):1663-73. doi: 10.1016/j.freeradbiomed.2008.09.010. Epub 2008 Sep 23.

PMID:
18845239
28.
29.
30.

Investigation of class characteristics in English handwriting of the three main racial groups: Chinese, Malay and Indian in Singapore.

Cheng N, Lee GK, Yap BS, Lee LT, Tan SK, Tan KP.

J Forensic Sci. 2005 Jan;50(1):177-84.

PMID:
15831016
31.

Bilateral optic neuropathy due to amiodarone with recurrence.

Clement CI, Myers P, Tan KP.

Clin Exp Ophthalmol. 2005 Apr;33(2):222-5. Review. No abstract available.

PMID:
15807838
32.

Phased-array magnetic resonance imaging of the prostate with correlation to radical prostatectomy specimens: local experience.

Kwek JW, Thng CH, Tan PH, Yuen JS, Khoo JB, Quek ST, Ho JT, Tan KP, Cheng CW.

Asian J Surg. 2004 Jul;27(3):219-24; discussion 225-6.

33.

Audit of diagnostic and interventional craniocervical catheter angiographic procedures at the Singapore General Hospital.

Low AS, Lim WE, Chan LL, Tan HM, Tan KP.

Ann Acad Med Singapore. 2004 Sep;33(5):607-13.

35.

Mammary gland morphogenesis is enhanced by exposure to flaxseed or its major lignan during suckling in rats.

Tan KP, Chen J, Ward WE, Thompson LU.

Exp Biol Med (Maywood). 2004 Feb;229(2):147-57.

PMID:
14734793
36.

Exposure to flaxseed or its purified lignan during suckling inhibits chemically induced rat mammary tumorigenesis.

Chen J, Tan KP, Ward WE, Thompson LU.

Exp Biol Med (Maywood). 2003 Sep;228(8):951-8.

PMID:
12968067
37.

Is myo-inositol a measure of glial swelling after stroke? A magnetic resonance study.

Rumpel H, Lim WE, Chang HM, Chan LL, Ho GL, Wong MC, Tan KP.

J Magn Reson Imaging. 2003 Jan;17(1):11-9.

PMID:
12500270
38.

Diffusion weighted MR imaging in acute stroke: the SGH experience.

Chan LL, Khoo JB, Thng CH, Lim WE, Tay KH, Tan EK, Chang HM, Chen C, Wong MC, Tan KP.

Singapore Med J. 2002 Mar;43(3):118-23.

PMID:
12005336
39.
40.

Correlation of the apparent diffusion coefficient and the creatine level in early ischemic stroke: a comparison of different patterns by magnetic resonance.

Rumpel H, Khoo JB, Chang HM, Lim WE, Chen C, Wong MC, Tan KP.

J Magn Reson Imaging. 2001 Mar;13(3):335-43.

PMID:
11241804
41.

Chronic isolated vertigo.

Chan LL, Tan EK, Tan KP.

Int J Clin Pract. 2000 Jul-Aug;54(6):407-8.

PMID:
11092118
42.

Spectrum of abnormal mammographic findings and their predictive value for malignancy in Singaporean women from a population screening trial.

Sng KW, Ng EH, Ng FC, Tan PH, Low SC, Chiang G, Ho GH, Ng LT, Wilde C, Tan KP.

Ann Acad Med Singapore. 2000 Jul;29(4):457-62.

PMID:
11056775
43.

Magnetic resonance imaging of brain metastases: magnetisation transfer or triple dose gadolinium?

Thng CH, Tay KH, Chan LL, Lim EH, Khoo BK, Huin EL, Tan KP.

Ann Acad Med Singapore. 1999 Jul;28(4):529-33.

PMID:
10561767
44.

Role of magnetic resonance imaging and magnetic resonance angiography in patients with hemifacial spasm.

Tan EK, Chan LL, Lim SH, Lim WE, Khoo JB, Tan KP.

Ann Acad Med Singapore. 1999 Mar;28(2):169-73.

PMID:
10497660
45.

X-linked adrenoleukodystrophy: spinocerebellar variant.

Tan EK, Lim SH, Chan LL, Wong MC, Tan KP.

Clin Neurol Neurosurg. 1999 Jun;101(2):137-40.

PMID:
10467913
46.

Reduction in retake rates and radiation dosage through computed radiography.

Polunin N, Lim TA, Tan KP.

Ann Acad Med Singapore. 1998 Nov;27(6):805-7.

PMID:
10101554
47.

Case report: Meningioma presenting as an aural polyp.

Huin E, Tan KP.

Clin Radiol. 1998 Aug;53(8):619-22. No abstract available.

PMID:
9744594
48.

Portable chest radiography: comparison of high-resolution digital displays with laser printed digital film.

Wong SK, Polunin N, Tan KP.

Ann Acad Med Singapore. 1998 Mar;27(2):178-81.

PMID:
9663305
49.

Results of intermediate measures from a population-based, randomized trial of mammographic screening prevalence and detection of breast carcinoma among Asian women: the Singapore Breast Screening Project.

Ng EH, Ng FC, Tan PH, Low SC, Chiang G, Tan KP, Seow A, Emmanuel S, Tan CH, Ho GH, Ng LT, Wilde CC.

Cancer. 1998 Apr 15;82(8):1521-8. Erratum in: Cancer 1998 Jul 1;83(1):191.

PMID:
9554530
50.

Radiological features in a patient with Kimura's disease.

Lim WE, Tan NG, Tan KP.

Singapore Med J. 1997 Mar;38(3):125-8. Review.

PMID:
9269381

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