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MEMRI-based imaging pipeline for guiding preclinical studies in mouse models of sporadic medulloblastoma.

Rallapalli H, Tan IL, Volkova E, Wojcinski A, Darwin BC, Lerch JP, Joyner AL, Turnbull DH.

Magn Reson Med. 2019 Aug 12. doi: 10.1002/mrm.27904. [Epub ahead of print]


Therapeutic outcomes in non-small cell lung cancer with BRAF mutations: a single institution, retrospective cohort study.

Tan I, Stinchcombe TE, Ready NE, Crawford J, Datto MB, Nagy RJ, Lanman RB, Gu L, Clarke JM.

Transl Lung Cancer Res. 2019 Jun;8(3):258-267. doi: 10.21037/tlcr.2019.04.03.


Germline Pathogenic Variants in Homologous Recombination and DNA Repair Genes in an Asian Cohort of Young-Onset Colorectal Cancer.

Toh MR, Chiang JB, Chong ST, Chan SH, Ishak NDB, Courtney E, Lee WH, Syed Abdillah Al SMFB, Carson Allen J Jr, Lim KH, Davila S, Tan P, Lim WK, Tan IBH, Ngeow J.

JNCI Cancer Spectr. 2018 Dec 10;2(4):pky054. doi: 10.1093/jncics/pky054. eCollection 2018 Oct.


CSF-1 controls cerebellar microglia and is required for motor function and social interaction.

Kana V, Desland FA, Casanova-Acebes M, Ayata P, Badimon A, Nabel E, Yamamuro K, Sneeboer M, Tan IL, Flanigan ME, Rose SA, Chang C, Leader A, Le Bourhis H, Sweet ES, Tung N, Wroblewska A, Lavin Y, See P, Baccarini A, Ginhoux F, Chitu V, Stanley ER, Russo SJ, Yue Z, Brown BD, Joyner AL, De Witte LD, Morishita H, Schaefer A, Merad M.

J Exp Med. 2019 Jul 26. pii: jem.20182037. doi: 10.1084/jem.20182037. [Epub ahead of print]


Progressive multifocal leukoencephalopathy in a patient with systemic lupus erythematosus: Clues to early diagnosis.

Law LY, Tan I, Prowse M, Sean Riminton D, Reddel SW.

J Clin Neurosci. 2019 Sep;67:261-263. doi: 10.1016/j.jocn.2019.06.030. Epub 2019 Jul 2.


Quantitative ultrasound for monitoring bone status in institutionalized adults with refractory epilepsy and intellectual disability: A 7-year follow-up study.

Cornelissen SLS, Berkvens JJL, Tan IY, Beerhorst K, Verschuure P, Mergler S, Majoie HJM, van den Bergh JPW.

Seizure. 2019 Jun 7;71:35-41. doi: 10.1016/j.seizure.2019.06.006. [Epub ahead of print]


PRL3-zumab as an immunotherapy to inhibit tumors expressing PRL3 oncoprotein.

Thura M, Al-Aidaroos AQ, Gupta A, Chee CE, Lee SC, Hui KM, Li J, Guan YK, Yong WP, So J, Chng WJ, Ng CH, Zhou J, Wang LZ, Yuen JSP, Ho HSS, Yi SM, Chiong E, Choo SP, Ngeow J, Ng MCH, Chua C, Yeo ESA, Tan IBH, Sng JXE, Tan NYZ, Thiery JP, Goh BC, Zeng Q.

Nat Commun. 2019 Jun 6;10(1):2484. doi: 10.1038/s41467-019-10127-x.


ADAMTS1 Promotes Adhesion to Extracellular Matrix Proteins and Predicts Prognosis in Early Stage Breast Cancer Patients.

Tan IA, Frewin K, Ricciardelli C, Russell DL.

Cell Physiol Biochem. 2019;52(6):1553-1568. doi: 10.33594/000000108.


Easy conversion of cardio-ankle vascular index into CAVI0: influence of scale coefficients.

Spronck B, Mestanik M, Tonhajzerova I, Jurko A, Tan I, Butlin M, Avolio AP.

J Hypertens. 2019 Sep;37(9):1913-1914. doi: 10.1097/HJH.0000000000002166. No abstract available.


Analytical Validation of Multiplex Biomarker Assay to Stratify Colorectal Cancer into Molecular Subtypes.

Ragulan C, Eason K, Fontana E, Nyamundanda G, Tarazona N, Patil Y, Poudel P, Lawlor RT, Del Rio M, Koo SL, Tan WS, Sclafani F, Begum R, Teixeira Mendes LS, Martineau P, Scarpa A, Cervantes A, Tan IB, Cunningham D, Sadanandam A.

Sci Rep. 2019 May 21;9(1):7665. doi: 10.1038/s41598-019-43492-0.


The chromatin structuring protein HMGA2 influences human subtelomere stability and cancer chemosensitivity.

Ahmed SM, Ramani PD, Wong SQR, Zhao X, Ivanyi-Nagy R, Leong TC, Chua C, Li Z, Hentze H, Tan IB, Yan J, DasGupta R, Dröge P.

PLoS One. 2019 May 8;14(5):e0215696. doi: 10.1371/journal.pone.0215696. eCollection 2019.


BDNF and NGF gene polymorphisms and urine BDNF-NGF levels in children with primary monosymptomatic nocturnal enuresis.

Ece A, Coşkun S, Şahin C, Tan I, Karabel D, Çim A.

J Pediatr Urol. 2019 May;15(3):255.e1-255.e7. doi: 10.1016/j.jpurol.2019.03.010. Epub 2019 Mar 20.


Update on Imaging of Knee Arthroplasties: Normal Findings and Hardware Complications.

Mar WA, Tan I, Song A, Omar IM, Taljanovic MS, Stacy GS.

Semin Musculoskelet Radiol. 2019 Apr;23(2):e20-e35. doi: 10.1055/s-0039-1677697. Epub 2019 Mar 29. Review.


Mood, anxiety, and perceived quality of life in adults with epilepsy and intellectual disability.

Snoeijen-Schouwenaars FM, van Ool JS, Tan IY, Aldenkamp AP, Schelhaas HJ, Hendriksen JGM.

Acta Neurol Scand. 2019 Jun;139(6):519-525. doi: 10.1111/ane.13085. Epub 2019 Mar 21.


27PDetection of genomic alterations in breast cancer (BC) patients with paired plasma and tumour specimens.

Yap YS, Ho D, Ng RC, Chan CH, Lee AS, Tan IB, Ng SBH.

Ann Oncol. 2019 Feb 1;30(Supplement_1). pii: mdz030.002. doi: 10.1093/annonc/mdz030.002. No abstract available.


Multicenter randomized crossover trial evaluating the provox luna in laryngectomized subjects.

Ratnayake CBB, Fles R, Tan IB, Baijens LWJ, Pilz W, Meeuwis CA, Janssen-van Det PHE, van Son R, Van den Brekel MWM.

Laryngoscope. 2019 Feb 20. doi: 10.1002/lary.27839. [Epub ahead of print]


Osteoporosis is inversely associated with arterial stiffness in the elderly: An investigation using the Osteoporosis Self-assessment Tool for Asians index in an elderly Chinese cohort.

Xuan Y, Wang W, Zhang H, Tan I, Butlin M, Avolio A, Zuo J.

J Clin Hypertens (Greenwich). 2019 Mar;21(3):405-411. doi: 10.1111/jch.13493. Epub 2019 Feb 7.


Parkin inhibits BAK and BAX apoptotic function by distinct mechanisms during mitophagy.

Bernardini JP, Brouwer JM, Tan IK, Sandow JJ, Huang S, Stafford CA, Bankovacki A, Riffkin CD, Wardak AZ, Czabotar PE, Lazarou M, Dewson G.

EMBO J. 2019 Jan 15;38(2). pii: e99916. doi: 10.15252/embj.201899916. Epub 2018 Dec 20.


Central aortic pressure improves prediction of cardiovascular events compared to peripheral blood pressure in short-term follow-up of a hypertensive cohort.

Zuo J, Chang G, Tan I, Butlin M, Chu SL, Avolio A.

Clin Exp Hypertens. 2018 Dec 16:1-8. doi: 10.1080/10641963.2018.1557682. [Epub ahead of print]


Diagnostic exome sequencing in 100 consecutive patients with both epilepsy and intellectual disability.

Snoeijen-Schouwenaars FM, van Ool JS, Verhoeven JS, van Mierlo P, Braakman HMH, Smeets EE, Nicolai J, Schoots J, Teunissen MWA, Rouhl RPW, Tan IY, Yntema HG, Brunner HG, Pfundt R, Stegmann AP, Kamsteeg EJ, Schelhaas HJ, Willemsen MH.

Epilepsia. 2019 Jan;60(1):155-164. doi: 10.1111/epi.14618. Epub 2018 Dec 7.


Effect of increasing heart rate on finger photoplethysmography fitness index (PPGF) in subjects with implanted cardiac pacemakers.

Aminuddin A, Tan I, Butlin M, Avolio AP, Kiat H, Barin E, Megat Mohd Nordin NA, Chellappan K.

PLoS One. 2018 Nov 28;13(11):e0207301. doi: 10.1371/journal.pone.0207301. eCollection 2018.


A seven-Gene Signature assay improves prognostic risk stratification of perioperative chemotherapy treated gastroesophageal cancer patients from the MAGIC trial.

Smyth EC, Nyamundanda G, Cunningham D, Fontana E, Ragulan C, Tan IB, Lin SJ, Wotherspoon A, Nankivell M, Fassan M, Lampis A, Hahne JC, Davies AR, Lagergren J, Gossage JA, Maisey N, Green M, Zylstra JL, Allum WH, Langley RE, Tan P, Valeri N, Sadanandam A.

Ann Oncol. 2018 Dec 1;29(12):2356-2362. doi: 10.1093/annonc/mdy407.


VDAC2 enables BAX to mediate apoptosis and limit tumor development.

Chin HS, Li MX, Tan IKL, Ninnis RL, Reljic B, Scicluna K, Dagley LF, Sandow JJ, Kelly GL, Samson AL, Chappaz S, Khaw SL, Chang C, Morokoff A, Brinkmann K, Webb A, Hockings C, Hall CM, Kueh AJ, Ryan MT, Kluck RM, Bouillet P, Herold MJ, Gray DHD, Huang DCS, van Delft MF, Dewson G.

Nat Commun. 2018 Nov 26;9(1):4976. doi: 10.1038/s41467-018-07309-4.


How often does computed tomography (CT) of the brain demonstrate a cause for psychosis? A 7-year retrospective study at a tertiary metropolitan hospital.

Harris G, Xiang H, Tan I, Randhawa V.

Australas Psychiatry. 2019 Apr;27(2):183-186. doi: 10.1177/1039856218815761. Epub 2018 Nov 26.


Sensitivity of Video-Based Pulse Arrival Time to Dynamic Blood Pressure Changes.

Shirbani F, Blackmore C, Kazzi C, Tan I, Butlin M, Avolio AP.

Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:3639-3641. doi: 10.1109/EMBC.2018.8513058.


Effects of instructed meditation augmented by computer-rendered artificial virtual environment on heart rate variability.

Kazzi C, Blackmore C, Shirbani F, Tan I, Butlin M, Avolio AP, Barin E.

Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:2768-2771. doi: 10.1109/EMBC.2018.8512816.


Author Correction: Reference component analysis of single-cell transcriptomes elucidates cellular heterogeneity in human colorectal tumors.

Li H, Courtois ET, Sengupta D, Tan Y, Chen KH, Goh JJL, Kong SL, Chua C, Hon LK, Tan WS, Wong M, Cima I, Tan MH, Wee LJK, Hillmer AM, Tan IB, Robson P, Prabhakar S.

Nat Genet. 2018 Dec;50(12):1754. doi: 10.1038/s41588-018-0299-1.


Spectrum of Voriconazole-Induced Periostitis With Review of the Differential Diagnosis.

Tan I, Lomasney L, Stacy GS, Lazarus M, Mar WA.

AJR Am J Roentgenol. 2019 Jan;212(1):157-165. doi: 10.2214/AJR.18.19991. Epub 2018 Nov 7.


Ultrasound measurement of central pulse pressure from carotid diameter: two for the price of one?

Avolio A, Tan I, Butlin M.

J Hypertens. 2018 Dec;36(12):2310-2311. doi: 10.1097/HJH.0000000000001889. No abstract available.


Classification of intellectual disability according to domains of adaptive functioning and between-domains discrepancy in adults with epilepsy.

van Ool JS, Snoeijen-Schouwenaars FM, Tan IY, Schelhaas HJ, Aldenkamp AP, Hendriksen JGM.

J Intellect Disabil Res. 2019 Jan;63(1):40-48. doi: 10.1111/jir.12556. Epub 2018 Oct 14.


Adult-onset leukoencephalopathy with neuroaxonal spheroids and pigmented glia mimicking systemic lupus erythematosus cerebral vasculitis.

Lubomski M, Buckland ME, Sy J, Wei H, Tan IYL, Kane B, Spring PJ.

J Neurol Sci. 2018 Dec 15;395:25-28. doi: 10.1016/j.jns.2018.09.025. Epub 2018 Sep 22. No abstract available.


Implementing the comprehensive unit-based safety program model to improve the management of mechanically ventilated patients in Saudi Arabia.

Khan RM, Al-Juaid M, Al-Mutairi H, Bibin G, Alchin J, Matroud A, Burrows V, Tan I, Zayer S, Naidv B, Kalantan B, Arabi YM.

Am J Infect Control. 2019 Jan;47(1):51-58. doi: 10.1016/j.ajic.2018.06.022. Epub 2018 Sep 5.


Challenging behavior in adults with epilepsy and intellectual disability: An analysis of epilepsy characteristics.

van Ool JS, Snoeijen-Schouwenaars FM, Tan IY, Jurgen Schelhaas H, Aldenkamp AP, Hendriksen JGM.

Epilepsy Behav. 2018 Sep;86:72-78. doi: 10.1016/j.yebeh.2018.06.028. Epub 2018 Jul 6.


Delayed onset of neurosarcoidosis after concurrent ipilimumab/nivolumab therapy.

Tan I, Malinzak M, Salama AKS.

J Immunother Cancer. 2018 Jul 31;6(1):77. doi: 10.1186/s40425-018-0390-2.


Real-Time Tumor Gene Expression Profiling to Direct Gastric Cancer Chemotherapy: Proof-of-Concept "3G" Trial.

Yong WP, Rha SY, Tan IB, Choo SP, Syn NL, Koh V, Tan SH, Asuncion BR, Sundar R, So JB, Shabbir A, Tan CS, Kim HS, Jung M, Chung HC, Ng MCH, Tai DW, Lee MH, Wu J, Yeoh KG, Tan P; Singapore Gastric Cancer Consortium (SGCC).

Clin Cancer Res. 2018 Nov 1;24(21):5272-5281. doi: 10.1158/1078-0432.CCR-18-0193. Epub 2018 Jul 25.


Systolic time intervals assessed from analysis of the carotid pressure waveform.

Salvi P, Grillo A, Tan I, Simon G, Salvi L, Gao L, Rovina M, Butlin M, Yang Y, Meneghin E, Meng L, Faini A, Barin E, Pini A, Carretta R, Huo Y, Avolio A, Parati G.

Physiol Meas. 2018 Aug 20;39(8):084002. doi: 10.1088/1361-6579/aad51b.


Cuffless Estimation of Blood Pressure: Importance of Variability in Blood Pressure Dependence of Arterial Stiffness Across Individuals and Measurement Sites.

Butlin M, Shirbani F, Barin E, Tan I, Spronck B, Avolio AP.

IEEE Trans Biomed Eng. 2018 Nov;65(11):2377-2383. doi: 10.1109/TBME.2018.2823333. Epub 2018 Apr 5.


Breast cancer in women with neurofibromatosis type 1 (NF1): a comprehensive case series with molecular insights into its aggressive phenotype.

Yap YS, Munusamy P, Lim C, Chan CHT, Prawira A, Loke SY, Lim SH, Ong KW, Yong WS, Ng SBH, Tan IBH, Callen DF, Lim JCT, Thike AA, Tan PH, Lee ASG.

Breast Cancer Res Treat. 2018 Oct;171(3):719-735. doi: 10.1007/s10549-018-4851-6. Epub 2018 Jun 21.


HER2 positive rates are enriched amongst colorectal cancer brain metastases: a study amongst 1920 consecutive patients.

Tan RYC, Camat MD, Ng M, Lim TH, Lim AST, Lim KH, Tan IBH.

Ann Oncol. 2018 Jul 1;29(7):1598-1603. doi: 10.1093/annonc/mdy156. No abstract available.


N-Point Moving Average: A Special Generalized Transfer Function Method for Estimation of Central Aortic Blood Pressure.

Xiao H, Butlin M, Qasem A, Tan I, Li D, Avolio AP.

IEEE Trans Biomed Eng. 2018 Jun;65(6):1226-1234. doi: 10.1109/TBME.2017.2710622.


Bystander CD8+ T cells are abundant and phenotypically distinct in human tumour infiltrates.

Simoni Y, Becht E, Fehlings M, Loh CY, Koo SL, Teng KWW, Yeong JPS, Nahar R, Zhang T, Kared H, Duan K, Ang N, Poidinger M, Lee YY, Larbi A, Khng AJ, Tan E, Fu C, Mathew R, Teo M, Lim WT, Toh CK, Ong BH, Koh T, Hillmer AM, Takano A, Lim TKH, Tan EH, Zhai W, Tan DSW, Tan IB, Newell EW.

Nature. 2018 May;557(7706):575-579. doi: 10.1038/s41586-018-0130-2. Epub 2018 May 16.


Human Innate Lymphoid Cell Subsets Possess Tissue-Type Based Heterogeneity in Phenotype and Frequency.

Simoni Y, Fehlings M, Kløverpris HN, McGovern N, Koo SL, Loh CY, Lim S, Kurioka A, Fergusson JR, Tang CL, Kam MH, Dennis K, Lim TKH, Fui ACY, Hoong CW, Chan JKY, Curotto de Lafaille M, Narayanan S, Baig S, Shabeer M, Toh SES, Tan HKK, Anicete R, Tan EH, Takano A, Klenerman P, Leslie A, Tan DSW, Tan IB, Ginhoux F, Newell EW.

Immunity. 2018 May 15;48(5):1060. doi: 10.1016/j.immuni.2018.04.028. No abstract available.


Association of Haemodynamic Indices of Central and Peripheral Pressure with Subclinical Target Organ Damage.

Zuo J, Chu S, Tan I, Butlin M, Zhao J, Avolio A.

Pulse (Basel). 2018 Mar;5(1-4):133-143. doi: 10.1159/000484441. Epub 2017 Nov 25.


Psychogenic nonepileptic seizures in adults with epilepsy and intellectual disability: A neglected area.

van Ool JS, Haenen AI, Snoeijen-Schouwenaars FM, Aldenkamp AP, Hendriksen JGM, Schelhaas HJ, Tan IY, Lazeron RHC, Bodde NMG.

Seizure. 2018 Jul;59:67-71. doi: 10.1016/j.seizure.2018.05.002. Epub 2018 May 4.


Beautiful Terraced Rice Fields in China.

Tan IK.

Clin Chem. 2018 May;64(5):877-878. doi: 10.1373/clinchem.2017.284182. No abstract available.


Quantitative and Label-Free Detection of Protein Kinase A Activity Based on Surface-Enhanced Raman Spectroscopy with Gold Nanostars.

He S, Kyaw YME, Tan EKM, Bekale L, Kang MWC, Kim SS, Tan I, Lam KP, Kah JCY.

Anal Chem. 2018 May 15;90(10):6071-6080. doi: 10.1021/acs.analchem.7b05417. Epub 2018 Apr 26.


A Case of IgG4-related Sclerosing Mesenteritis.

Butt Z, Alam SH, Semeniuk O, Singh S, Chhabra GS, Tan IJ.

Cureus. 2018 Feb 3;10(2):e2147. doi: 10.7759/cureus.2147.


Support values through the eyes of the patient: An exploratory study into long-term support of persons with refractory epilepsy.

Buntinx WHE, Tan IY, Aldenkamp AP.

Epilepsy Behav. 2018 May;82:155-163. doi: 10.1016/j.yebeh.2018.02.031. Epub 2018 Apr 4.


Does increase in arterial stiffness and wave reflection precede development of placental-mediated complications in pregnancy?

Tan I, Butlin M, Avolio A.

J Hypertens. 2018 May;36(5):1029-1031. doi: 10.1097/HJH.0000000000001669. No abstract available.


Cerebral Haemodynamics: Effects of Systemic Arterial Pulsatile Function and Hypertension.

Avolio A, Kim MO, Adji A, Gangoda S, Avadhanam B, Tan I, Butlin M.

Curr Hypertens Rep. 2018 Mar 19;20(3):20. doi: 10.1007/s11906-018-0822-x. Review.


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