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RIG-I Activation by a Designer Short RNA Ligand Protects Human Immune Cells against Dengue Virus Infection without Causing Cytotoxicity.

Ho V, Yong HY, Chevrier M, Narang V, Lum J, Toh YX, Lee B, Chen J, Tan EY, Luo D, Fink K.

J Virol. 2019 Jun 28;93(14). pii: e00102-19. doi: 10.1128/JVI.00102-19. Print 2019 Jul 15.


Importance of Social Support Within the Nursing Staff on Agitation in Residents With Dementia.

Tan EYL, de Vugt ME, Köhler S, Verhey FRJ, Schols JMGA.

J Am Med Dir Assoc. 2019 Jun;20(6):785-786. doi: 10.1016/j.jamda.2019.03.002. Epub 2019 Apr 16. No abstract available.


Breast-conserving surgery versus mastectomy in young women with breast cancer in Asian settings.

Sinnadurai S, Kwong A, Hartman M, Tan EY, Bhoo-Pathy NT, Dahlui M, See MH, Yip CH, Taib NA, Bhoo-Pathy N.

BJS Open. 2018 Oct 18;3(1):48-55. doi: 10.1002/bjs5.50111. eCollection 2019 Feb.


Depressive Symptoms in Mild Cognitive Impairment and the Risk of Dementia: A Systematic Review and Comparative Meta-Analysis of Clinical and Community-Based Studies.

Tan EYL, Köhler S, Hamel REG, Muñoz-Sánchez JL, Verhey FRJ, Ramakers IHGB.

J Alzheimers Dis. 2019;67(4):1319-1329. doi: 10.3233/JAD-180513.


A cross-sectional survey on cold chain management of vaccines in Cebu, Philippines.

Maglasang PL, Butalid ML, Pastoril MF, Pratama AN, Tan EY.

Pharm Pract (Granada). 2018 Apr-Jun;16(2):1167. doi: 10.18549/PharmPract.2018.02.1167. Epub 2018 Jun 22.


Hypoxic tumor microenvironment activates GLI2 via HIF-1α and TGF-β2 to promote chemoresistance in colorectal cancer.

Tang YA, Chen YF, Bao Y, Mahara S, Yatim SMJM, Oguz G, Lee PL, Feng M, Cai Y, Tan EY, Fong SS, Yang ZH, Lan P, Wu XJ, Yu Q.

Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):E5990-E5999. doi: 10.1073/pnas.1801348115. Epub 2018 Jun 11.


Improved Bioavailability of Levodopa Using Floatable Spray-Coated Microcapsules for the Management of Parkinson's Disease.

Baek JS, Tee JK, Pang YY, Tan EY, Lim KL, Ho HK, Loo SCJ.

Neuromolecular Med. 2018 Jun;20(2):262-270. doi: 10.1007/s12017-018-8491-0. Epub 2018 Apr 25.


Erratum: Publisher Correction: A potent neutralizing antibody with therapeutic potential against all four serotypes of dengue virus.

Xu M, Zuest R, Velumani S, Tukijan F, Toh YX, Appanna R, Tan EY, Cerny D, MacAry P, Wang CI, Fink K.

NPJ Vaccines. 2018 Feb 1;3:7. doi: 10.1038/s41541-018-0044-x. eCollection 2018.


A potent neutralizing antibody with therapeutic potential against all four serotypes of dengue virus.

Xu M, Zuest R, Velumani S, Tukijan F, Toh YX, Appanna R, Tan EY, Cerny D, MacAry P, Wang CI, Fink K.

NPJ Vaccines. 2017 Jan 23;2:2. doi: 10.1038/s41541-016-0003-3. eCollection 2017. Erratum in: NPJ Vaccines. 2018 Feb 1;3:7.


GNA13 expression promotes drug resistance and tumor-initiating phenotypes in squamous cell cancers.

Rasheed SAK, Leong HS, Lakshmanan M, Raju A, Dadlani D, Chong FT, Shannon NB, Rajarethinam R, Skanthakumar T, Tan EY, Hwang JSG, Lim KH, Tan DS, Ceppi P, Wang M, Tergaonkar V, Casey PJ, Iyer NG.

Oncogene. 2018 Mar;37(10):1340-1353. doi: 10.1038/s41388-017-0038-6. Epub 2017 Dec 19.


A highly printable and biocompatible hydrogel composite for direct printing of soft and perfusable vasculature-like structures.

Suntornnond R, Tan EYS, An J, Chua CK.

Sci Rep. 2017 Dec 4;7(1):16902. doi: 10.1038/s41598-017-17198-0.


Majority of flat epithelial atypia diagnosed on biopsy do not require surgical excision.

Chan PMY, Chotai N, Lai ES, Sin PY, Chen J, Lu SQ, Goh MH, Chong BK, Ho BCS, Tan EY.

Breast. 2018 Feb;37:13-17. doi: 10.1016/j.breast.2017.10.005. Epub 2017 Oct 15.


Chromosome 1q21.3 amplification is a trackable biomarker and actionable target for breast cancer recurrence.

Goh JY, Feng M, Wang W, Oguz G, Yatim SMJM, Lee PL, Bao Y, Lim TH, Wang P, Tam WL, Kodahl AR, Lyng MB, Sarma S, Lin SY, Lezhava A, Yap YS, Lim AST, Hoon DSB, Ditzel HJ, Lee SC, Tan EY, Yu Q.

Nat Med. 2017 Nov;23(11):1319-1330. doi: 10.1038/nm.4405. Epub 2017 Sep 25.


A Mathematical Model on the Resolution of Extrusion Bioprinting for the Development of New Bioinks.

Suntornnond R, Tan EYS, An J, Chua CK.

Materials (Basel). 2016 Sep 6;9(9). pii: E756. doi: 10.3390/ma9090756.


Outcome after neoadjuvant chemotherapy in Asian breast cancer patients.

Lim LY, Miao H, Lim JS, Lee SC, Bhoo-Pathy N, Yip CH, Taib NA, Chan P, Tan EY, Lim SH, Lim GH, Woo E, Tan YS, Lee JA, Wong M, Tan PH, Ong KW, Wong FY, Yap YS, Hartman M.

Cancer Med. 2017 Jan;6(1):173-185. doi: 10.1002/cam4.985. Epub 2016 Dec 20.


Significant Effect of Polymorphisms in CYP2D6 on Response to Tamoxifen Therapy for Breast Cancer: A Prospective Multicenter Study.

Zembutsu H, Nakamura S, Akashi-Tanaka S, Kuwayama T, Watanabe C, Takamaru T, Takei H, Ishikawa T, Miyahara K, Matsumoto H, Hasegawa Y, Kutomi G, Shima H, Satomi F, Okazaki M, Zaha H, Onomura M, Matsukata A, Sagara Y, Baba S, Yamada A, Shimada K, Shimizu D, Tsugawa K, Shimo A, Tan EY, Hartman M, Chan CW, Lee SC, Nakamura Y.

Clin Cancer Res. 2017 Apr 15;23(8):2019-2026. doi: 10.1158/1078-0432.CCR-16-1779. Epub 2016 Oct 19.


Validation of the CancerMath prognostic tool for breast cancer in Southeast Asia.

Miao H, Hartman M, Verkooijen HM, Taib NA, Wong HS, Subramaniam S, Yip CH, Tan EY, Chan P, Lee SC, Bhoo-Pathy N.

BMC Cancer. 2016 Oct 21;16(1):820.


Telomerase reverse transcriptase promotes cancer cell proliferation by augmenting tRNA expression.

Khattar E, Kumar P, Liu CY, Akıncılar SC, Raju A, Lakshmanan M, Maury JJ, Qiang Y, Li S, Tan EY, Hui KM, Shi M, Loh YH, Tergaonkar V.

J Clin Invest. 2016 Oct 3;126(10):4045-4060. doi: 10.1172/JCI86042. Epub 2016 Sep 19.


A High-Dimensional Atlas of Human T Cell Diversity Reveals Tissue-Specific Trafficking and Cytokine Signatures.

Wong MT, Ong DE, Lim FS, Teng KW, McGovern N, Narayanan S, Ho WQ, Cerny D, Tan HK, Anicete R, Tan BK, Lim TK, Chan CY, Cheow PC, Lee SY, Takano A, Tan EH, Tam JK, Tan EY, Chan JK, Fink K, Bertoletti A, Ginhoux F, Curotto de Lafaille MA, Newell EW.

Immunity. 2016 Aug 16;45(2):442-56. doi: 10.1016/j.immuni.2016.07.007. Epub 2016 Aug 9.


High expression of MnSOD promotes survival of circulating breast cancer cells and increases their resistance to doxorubicin.

Fu A, Ma S, Wei N, Tan BX, Tan EY, Luo KQ.

Oncotarget. 2016 Aug 2;7(31):50239-50257. doi: 10.18632/oncotarget.10360.


Corrigendum: IRAK1 is a therapeutic target that drives breast cancer metastasis and resistance to paclitaxel.

Wee ZN, Yatim SMJM, Kohlabauer VK, Feng M, Goh JY, Bao Y, Lee PL, Zhang S, Wang PP, Lim E, Tam WL, Cai Y, Ditzel HJ, Hoon DSB, Tan EY, Yu Q.

Nat Commun. 2015 Nov 20;6:10054. doi: 10.1038/ncomms10054. No abstract available.


Mastectomy rates remain high in Singapore and are not associated with poorer survival after adjusting for age.

Chan PM, Choo BA, Zhang T, Seah MD, Chen JJ, Lu SQ, Tan EY.

Springerplus. 2015 Nov 10;4:685. doi: 10.1186/s40064-015-1460-2. eCollection 2015.


Trends in presentation, management and survival of patients with de novo metastatic breast cancer in a Southeast Asian setting.

Bhoo-Pathy N, Verkooijen HM, Tan EY, Miao H, Taib NA, Brand JS, Dent RA, See MH, Subramaniam S, Chan P, Lee SC, Hartman M, Yip CH.

Sci Rep. 2015 Nov 5;5:16252. doi: 10.1038/srep16252.


IRAK1 is a therapeutic target that drives breast cancer metastasis and resistance to paclitaxel.

Wee ZN, Yatim SM, Kohlbauer VK, Feng M, Goh JY, Bao Y, Lee PL, Zhang S, Wang PP, Lim E, Tam WL, Cai Y, Ditzel HJ, Hoon DS, Tan EY, Yu Q.

Nat Commun. 2015 Oct 27;6:8746. doi: 10.1038/ncomms9746. Erratum in: Nat Commun. 2015;6:10054. Yi, Bao [Corrected to Bao, Yi].


Delivery of doxorubicin and paclitaxel from double-layered microparticles: The effects of layer thickness and dual-drug vs. single-drug loading.

Lee WL, Guo WM, Ho VHB, Saha A, Chong HC, Tan NS, Tan EY, Loo SCJ.

Acta Biomater. 2015 Nov;27:53-65. doi: 10.1016/j.actbio.2015.08.051. Epub 2015 Sep 1.


Prognostic role of adjuvant radiotherapy in triple-negative breast cancer: A historical cohort study.

Bhoo-Pathy N, Verkooijen HM, Wong FY, Pignol JP, Kwong A, Tan EY, Aishah Taib N, Nei WL, Ho GF, Tan B, Chan P, Lee SC, Hartman M, Yip CH, Dent R.

Int J Cancer. 2015 Nov 15;137(10):2504-12. doi: 10.1002/ijc.29617. Epub 2015 Jul 14.


Extent of margin involvement, lymphovascular invasion, and extensive intraductal component predict for residual disease after wide local excision for breast cancer.

Alrahbi S, Chan PM, Ho BC, Seah MD, Chen JJ, Tan EY.

Clin Breast Cancer. 2015 Jun;15(3):219-26. doi: 10.1016/j.clbc.2014.12.004. Epub 2014 Dec 24.


Selective susceptibility of human skin antigen presenting cells to productive dengue virus infection.

Cerny D, Haniffa M, Shin A, Bigliardi P, Tan BK, Lee B, Poidinger M, Tan EY, Ginhoux F, Fink K.

PLoS Pathog. 2014 Dec 4;10(12):e1004548. doi: 10.1371/journal.ppat.1004548. eCollection 2014 Dec.


RASAL2 activates RAC1 to promote triple-negative breast cancer progression.

Feng M, Bao Y, Li Z, Li J, Gong M, Lam S, Wang J, Marzese DM, Donovan N, Tan EY, Hoon DS, Yu Q.

J Clin Invest. 2014 Dec;124(12):5291-304. doi: 10.1172/JCI76711. Epub 2014 Nov 10.


Limiting the use of primary endocrine therapy in elderly women with breast cancer.

Chan SW, Chan PM, Seah MD, Chen JJ, Tan EY.

Ann Acad Med Singapore. 2014 Sep;43(9):469-72.


Adopting ambulatory breast cancer surgery as the standard of care in an asian population.

Ng YY, Chan PM, Chen JJ, Seah MD, Teo C, Tan EY.

Int J Breast Cancer. 2014;2014:672743. doi: 10.1155/2014/672743. Epub 2014 Aug 12.


Inhibition of 3-D tumor spheroids by timed-released hydrophilic and hydrophobic drugs from multilayered polymeric microparticles.

Lee WL, Guo WM, Ho VH, Saha A, Chong HC, Tan NS, Widjaja E, Tan EY, Loo SC.

Small. 2014 Oct 15;10(19):3986-96. doi: 10.1002/smll.201400536. Epub 2014 Jun 20.


Development of a magnetic 3D spheroid platform with potential application for high-throughput drug screening.

Guo WM, Loh XJ, Tan EY, Loo JS, Ho VH.

Mol Pharm. 2014 Jul 7;11(7):2182-9. doi: 10.1021/mp5000604. Epub 2014 May 29.


Predicting survival of de novo metastatic breast cancer in Asian women: systematic review and validation study.

Miao H, Hartman M, Bhoo-Pathy N, Lee SC, Taib NA, Tan EY, Chan P, Moons KG, Wong HS, Goh J, Rahim SM, Yip CH, Verkooijen HM.

PLoS One. 2014 Apr 2;9(4):e93755. doi: 10.1371/journal.pone.0093755. eCollection 2014. Review.


The use of traditional Chinese medicine among breast cancer patients: implications for the clinician.

Wong KY, Tan EY, Chen JJ, Teo C, Chan PM.

Ann Acad Med Singapore. 2014 Feb;43(2):74-8.


Blue dye is sufficient for sentinel lymph node biopsy in breast cancer.

Ang CH, Tan MY, Teo C, Seah DW, Chen JC, Chan MY, Tan EY.

Br J Surg. 2014 Mar;101(4):383-9; discussion 389. doi: 10.1002/bjs.9390. Epub 2014 Feb 3.


Sentinel Lymph Node Biopsy Should Be Included with the Initial Surgery for High-Risk Ductal Carcinoma-In-Situ.

Tan EY, Lo ZW, Ang CH, Teo C, Seah MD, Chen JJ, Chan PM.

Int Sch Res Notices. 2014 Oct 29;2014:624185. doi: 10.1155/2014/624185. eCollection 2014.


ALDH1 expression is enriched in breast cancers arising in young women but does not predict outcome.

Tan EY, Thike AA; Breast Surgical Team at Outram, Tan PH.

Br J Cancer. 2013 Jul 9;109(1):109-13. doi: 10.1038/bjc.2013.297. Epub 2013 Jun 20.


Protein tyrosine phosphatase UBASH3B is overexpressed in triple-negative breast cancer and promotes invasion and metastasis.

Lee ST, Feng M, Wei Y, Li Z, Qiao Y, Guan P, Jiang X, Wong CH, Huynh K, Wang J, Li J, Karuturi KM, Tan EY, Hoon DS, Kang Y, Yu Q.

Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):11121-6. doi: 10.1073/pnas.1300873110. Epub 2013 Jun 19.


Manipulating magnetic 3D spheroids in hanging drops for applications in tissue engineering and drug screening.

Ho VH, Guo WM, Huang CL, Ho SF, Chaw SY, Tan EY, Ng KW, Loo JS.

Adv Healthc Mater. 2013 Nov;2(11):1430-4. doi: 10.1002/adhm.201200408. Epub 2013 Apr 19.


Achieving breast cancer surgery in a single setting with intraoperative frozen section analysis of the sentinel lymph node.

Lu Q, Tan EY, Ho B, Teo C, Seah MD, Chen JJ, Chan PM.

Clin Breast Cancer. 2013 Apr;13(2):140-5. doi: 10.1016/j.clbc.2012.11.005. Epub 2012 Dec 5.


Advanced breast cancer-are we doing enough?

Pek CH, Tan EY, Chen JJ, Ho PW, Teo C, Earnest A, Chan PM.

Breast J. 2012 Nov-Dec;18(6):644-6. doi: 10.1111/tbj.12020. Epub 2012 Sep 26. No abstract available.


Non-demyelinating, reversible conduction failure in Fisher syndrome and related disorders.

Umapathi T, Tan EY, Kokubun N, Verma K, Yuki N.

J Neurol Neurosurg Psychiatry. 2012 Sep;83(9):941-8. doi: 10.1136/jnnp-2012-303079. Epub 2012 Jul 5.


Surgical excision of intraductal breast papilloma diagnosed on core biopsy.

Lu Q, Tan EY, Ho B, Chen JJ, Chan PM.

ANZ J Surg. 2012 Mar;82(3):168-72. doi: 10.1111/j.1445-2197.2011.05969.x. Epub 2012 Jan 17.


The role of morbidity and mortality meetings in interventional radiology.

Mok PS, Tan EY, Baerlocher MO, Athreya S.

Eur J Radiol. 2012 Nov;81(11):3344-7. doi: 10.1016/j.ejrad.2012.01.005. Epub 2012 Jan 31.


Predictors of nonsentinel nodal involvement to aid intraoperative decision making in breast cancer patients with positive sentinel lymph nodes.

Tan EY, Ho B, Chen JJ, Ho PW, Teo C, Earnest A, Chan PM.

ISRN Oncol. 2011;2011:539503. doi: 10.5402/2011/539503. Epub 2011 Aug 16.


Comparison of Canadian medical graduates and international medical graduates in Canada: 1989-2007.

Mok PS, Baerlocher MO, Abrahams C, Tan EY, Slade S, Verma S.

Acad Med. 2011 Aug;86(8):962-7. doi: 10.1097/ACM.0b013e318222e314.


On the utility of diagnostic instruments for pediatric delirium in critical illness: an evaluation of the Pediatric Anesthesia Emergence Delirium Scale, the Delirium Rating Scale 88, and the Delirium Rating Scale-Revised R-98.

Janssen NJ, Tan EY, Staal M, Janssen EP, Leroy PL, Lousberg R, van Os J, Schieveld JN.

Intensive Care Med. 2011 Aug;37(8):1331-7. doi: 10.1007/s00134-011-2244-y. Epub 2011 May 13.


Pharmacokinetics and antitumor activity of patupilone combined with midazolam or omeprazole in patients with advanced cancer.

Tsimberidou AM, Lewis N, Reid T, Burris H, Urban P, Tan EY, Anand S, Uehara C, Kurzrock R.

Cancer Chemother Pharmacol. 2011 Dec;68(6):1507-16. doi: 10.1007/s00280-011-1635-7. Epub 2011 Apr 17.


Effects of imatinib mesylate on the pharmacokinetics of paracetamol (acetaminophen) in Korean patients with chronic myelogenous leukaemia.

Kim DW, Tan EY, Jin Y, Park S, Hayes M, Demirhan E, Schran H, Wang Y.

Br J Clin Pharmacol. 2011 Feb;71(2):199-206. doi: 10.1111/j.1365-2125.2010.03810.x.

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